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Researchers develop innovative and flexible method to study immune cell capabilities

Researchers develop innovative and flexible method to study immune cell capabilities

byNational University of SingaporeSchematic of PAINTKiller assay. a, Preparation of affinity matrix on effector cells. Effector cells were first labeled with anti-CD45 conjugated with streptavid

Researchers develop innovative and flexible method to study immune cell capabilities

byNational University of SingaporeSchematic of PAINTKiller assay. a, Preparation of affinity matrix on effector cells. Effector cells were first labeled with anti-CD45 conjugated with streptavid
New insight into the protein mutations that cause Rett syndrome

New insight into the protein mutations that cause Rett syndrome

byRockefeller UniversityWorking model for normal MeCP2 function on chromatin and its dysregulation in disease. Credit:Nature Structural & Molecular Biology(2024). DOI: 10.1038/s4

New insight into the protein mutations that cause Rett syndrome

byRockefeller UniversityWorking model for normal MeCP2 function on chromatin and its dysregulation in disease. Credit:Nature Structural & Molecular Biology(2024). DOI: 10.1038/s4
Improving the diagnosis of infection: A prospective study clarifies the role of an innovative metagenomic tool

Improving the diagnosis of infection: A prospective study clarifies the role of an innovative metagenomic tool

byPasteur InstituteCharacteristics of samples analyzed by mNGS(A) Distribution of sample types among the 742 samples analyzed by mNGS in the present study. (B) Distribution of the sample origins

Improving the diagnosis of infection: A prospective study clarifies the role of an innovative metagenomic tool

byPasteur InstituteCharacteristics of samples analyzed by mNGS(A) Distribution of sample types among the 742 samples analyzed by mNGS in the present study. (B) Distribution of the sample origins
Targeting the racial disparity in kidney disease

Targeting the racial disparity in kidney disease

Some people of West African descent face a higher risk of renal failure. New drugs based on gene research may help right the ship — if they can reach everyone who needs them.

Targeting the racial disparity in kidney disease

Some people of West African descent face a higher risk of renal failure. New drugs based on gene research may help right the ship — if they can reach everyone who needs them.
Study discovers novel biomarker for vascular aging and neurodegeneration

Study discovers novel biomarker for vascular aging and neurodegeneration

by Melissa Rohman and Olivia Dimmer,Northwestern UniversityNotch3 deficiency results in vascular dysfunction due to impaired contractility. Immunofluorescence of phosphorylated myosin light chai

Study discovers novel biomarker for vascular aging and neurodegeneration

by Melissa Rohman and Olivia Dimmer,Northwestern UniversityNotch3 deficiency results in vascular dysfunction due to impaired contractility. Immunofluorescence of phosphorylated myosin light chai
New platform streamlines epitope comparison in antibody research

New platform streamlines epitope comparison in antibody research

by Tokyo Institute of TechnologyThe novel Epitope Binning-seq technology streamlines antibody epitope mapping and enables the simultaneous evaluation of large numbers of genetically encoded antib

New platform streamlines epitope comparison in antibody research

by Tokyo Institute of TechnologyThe novel Epitope Binning-seq technology streamlines antibody epitope mapping and enables the simultaneous evaluation of large numbers of genetically encoded antib
Melatonin and carcinogenesis in mice: The 50th anniversary of relationships

Melatonin and carcinogenesis in mice: The 50th anniversary of relationships

by Impact Journals LLCTrends in the annual numbers of publications. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.28537A new research perspective titled "Melatonin and carcinogene

Melatonin and carcinogenesis in mice: The 50th anniversary of relationships

by Impact Journals LLCTrends in the annual numbers of publications. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.28537A new research perspective titled "Melatonin and carcinogene
Lifespan increases in mice when specific brain cells are activated, study finds

Lifespan increases in mice when specific brain cells are activated, study finds

by Julia Evangelou Strait,Washington University School of MedicineWith age, the researchers found that the protein Ppp1r17 tends to leave the nucleus of the neurons, and when that happens, the n

Lifespan increases in mice when specific brain cells are activated, study finds

by Julia Evangelou Strait,Washington University School of MedicineWith age, the researchers found that the protein Ppp1r17 tends to leave the nucleus of the neurons, and when that happens, the n
Mifepristone access is coming before the US Supreme Court. How safe is this abortion pill?

Mifepristone access is coming before the US Supreme Court. How safe is this abortion pill?

by LAURA UNGAR and MATTHEW PERRONEBoxes of the drug mifepristone sit on a shelf at the West Alabama Women's Center in Tuscaloosa, Ala., on March 16, 2022. On Tuesday, March 26, 2024, the U.S. Supr

Mifepristone access is coming before the US Supreme Court. How safe is this abortion pill?

by LAURA UNGAR and MATTHEW PERRONEBoxes of the drug mifepristone sit on a shelf at the West Alabama Women's Center in Tuscaloosa, Ala., on March 16, 2022. On Tuesday, March 26, 2024, the U.S. Supr
Comparing human and mouse Purkinje cells to better understand human brain complexity

Comparing human and mouse Purkinje cells to better understand human brain complexity

by Bob Yirka , Medical XpressHuman and mouse PC morphological properties. a Morphological reconstructions of a mouse and a human PC obtained from fluorescent confocal images of postmortem fixated brai

Comparing human and mouse Purkinje cells to better understand human brain complexity

by Bob Yirka , Medical XpressHuman and mouse PC morphological properties. a Morphological reconstructions of a mouse and a human PC obtained from fluorescent confocal images of postmortem fixated brai
Researchers identify a potential target for reversing poor metabolic traits

Researchers identify a potential target for reversing poor metabolic traits

by Brandon Chase,Massachusetts General HospitalGraphical abstract. Credit:Cell Metabolism(2023). DOI: 10.1016/j.cmet.2023.11.010During oxidative stress, excess production of reactive

Researchers identify a potential target for reversing poor metabolic traits

by Brandon Chase,Massachusetts General HospitalGraphical abstract. Credit:Cell Metabolism(2023). DOI: 10.1016/j.cmet.2023.11.010During oxidative stress, excess production of reactive