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Breakthroughs
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Genetic testing pinpoints cardiovascular risk in patients with aortic disorders

Genetic testing pinpoints cardiovascular risk in patients with aortic disorders

by Vincent Jacobbi,Mayo ClinicCredit: Pixabay/CC0 Public DomainA new Mayo Clinic systematicreview, published in theJournal of Vascular Surgeryhas shed light on genetically inhe

Genetic testing pinpoints cardiovascular risk in patients with aortic disorders

by Vincent Jacobbi,Mayo ClinicCredit: Pixabay/CC0 Public DomainA new Mayo Clinic systematicreview, published in theJournal of Vascular Surgeryhas shed light on genetically inhe
New monoclonal antibody for treating cerebral ischemia injury

New monoclonal antibody for treating cerebral ischemia injury

FEBRUARY 27, 2024byThe University of Hong KongProfessor Ruby Hoo Lai-chong (first, right), Department of Pharmacology and Pharmacy of HKUMed, and her research team have successfully developed a

New monoclonal antibody for treating cerebral ischemia injury

FEBRUARY 27, 2024byThe University of Hong KongProfessor Ruby Hoo Lai-chong (first, right), Department of Pharmacology and Pharmacy of HKUMed, and her research team have successfully developed a
Experimental compound extends life in amyotrophic lateral sclerosis mouse model

Experimental compound extends life in amyotrophic lateral sclerosis mouse model

FEBRUARY 6, 2024byUT Southwestern Medical CenterMAP4K interactome and the effect on RANGAP1 subcellular distribution.AWestern-blotting analysis of proteins after proximity labeling i

Experimental compound extends life in amyotrophic lateral sclerosis mouse model

FEBRUARY 6, 2024byUT Southwestern Medical CenterMAP4K interactome and the effect on RANGAP1 subcellular distribution.AWestern-blotting analysis of proteins after proximity labeling i
Interactions between flu subtypes found to predict epidemic severity more than virus evolution

Interactions between flu subtypes found to predict epidemic severity more than virus evolution

by Emily PackerEmily Packer,eLifeAntigenic and genetic evolution of seasonal influenza A(H3N2) viruses, 1997—2019. A-B.Temporal phylogenies of hemagglutinin (H3) and neuraminidase (N2) gene segm

Interactions between flu subtypes found to predict epidemic severity more than virus evolution

by Emily PackerEmily Packer,eLifeAntigenic and genetic evolution of seasonal influenza A(H3N2) viruses, 1997—2019. A-B.Temporal phylogenies of hemagglutinin (H3) and neuraminidase (N2) gene segm
Research harnesses machine learning and imaging to give insight into stem cell behavior

Research harnesses machine learning and imaging to give insight into stem cell behavior

by Greta Harrison,University of Southern CaliforniaSingle hematopoietic stem cells dividing metabolically (m) symmetrically and asymmetrically, measured by the research team’s imaging technique.

Research harnesses machine learning and imaging to give insight into stem cell behavior

by Greta Harrison,University of Southern CaliforniaSingle hematopoietic stem cells dividing metabolically (m) symmetrically and asymmetrically, measured by the research team’s imaging technique.
Disruption of mitochondrial unfolded protein response yields shortening of telomeres in mouse oocytes, somatic cells

Disruption of mitochondrial unfolded protein response yields shortening of telomeres in mouse oocytes, somatic cells

FEBRUARY 21, 2024by Impact Journals LLCRepresentative confocal images of TRF1 expression and TRF/H2AX co-localization in cumulus oophorus isolated from 6-month-old wild-type and Clpp−/−mice. Cre

Disruption of mitochondrial unfolded protein response yields shortening of telomeres in mouse oocytes, somatic cells

FEBRUARY 21, 2024by Impact Journals LLCRepresentative confocal images of TRF1 expression and TRF/H2AX co-localization in cumulus oophorus isolated from 6-month-old wild-type and Clpp−/−mice. Cre
Team develops a single-nucleus resolution atlas of white adipose tissue in different depots

Team develops a single-nucleus resolution atlas of white adipose tissue in different depots

FEBRUARY 5, 2024by Higher Education PressWorkflow to perform snRNA-seq of different WAT depots. The nuclei were derived from subcutaneous (S), epididymal (E), mesenteric (M), peri-nephritic (N), and p

Team develops a single-nucleus resolution atlas of white adipose tissue in different depots

FEBRUARY 5, 2024by Higher Education PressWorkflow to perform snRNA-seq of different WAT depots. The nuclei were derived from subcutaneous (S), epididymal (E), mesenteric (M), peri-nephritic (N), and p
Examining the potential of the common bovine as a potential therapeutic research model

Examining the potential of the common bovine as a potential therapeutic research model

by Tom Fleischman,Cornell UniversityGraphical Abstract. Credit:iScience(2024). DOI: 10.1016/j.isci.2024.108886Research involving animal models—for purposes such as developing new vac

Examining the potential of the common bovine as a potential therapeutic research model

by Tom Fleischman,Cornell UniversityGraphical Abstract. Credit:iScience(2024). DOI: 10.1016/j.isci.2024.108886Research involving animal models—for purposes such as developing new vac
Systematic review links outdoor air pollution to differences in children's brains

Systematic review links outdoor air pollution to differences in children's brains

by Alex Russell,UC DavisCredit: Pixabay/CC0 Public DomainOutdoor air pollution from power plants, fires and cars continues to degrade human, animal and environmental health around the globe. New

Systematic review links outdoor air pollution to differences in children's brains

by Alex Russell,UC DavisCredit: Pixabay/CC0 Public DomainOutdoor air pollution from power plants, fires and cars continues to degrade human, animal and environmental health around the globe. New
Team assesses biological functions, diseases and therapeutic targets of heat shock protein 90

Team assesses biological functions, diseases and therapeutic targets of heat shock protein 90

by Sichuan International Medical Exchange and Promotion AssociationHSP90 chaperone undergoes dynamic cycling process: HSP90 transits between open and closed states to promote maturation of polypeptide

Team assesses biological functions, diseases and therapeutic targets of heat shock protein 90

by Sichuan International Medical Exchange and Promotion AssociationHSP90 chaperone undergoes dynamic cycling process: HSP90 transits between open and closed states to promote maturation of polypeptide
Extra fingers and hearts: Pinpointing changes to our genetic instructions that disrupt development

Extra fingers and hearts: Pinpointing changes to our genetic instructions that disrupt development

by Mario Aguilera,University of California - San DiegoChanging the instructions for development: Single-letter changes to genomes led to the formation of an extra digit (right). Credit: Fabian L

Extra fingers and hearts: Pinpointing changes to our genetic instructions that disrupt development

by Mario Aguilera,University of California - San DiegoChanging the instructions for development: Single-letter changes to genomes led to the formation of an extra digit (right). Credit: Fabian L
Prairie voles display signs of human-like depression, show promise as animal model

Prairie voles display signs of human-like depression, show promise as animal model

by University of Texas at El PasoSergio Iñiguez, Ph.D., a professor of psychology at The University of Texas at El Paso, points out the symptoms of depression in voles to doctoral student Minerva

Prairie voles display signs of human-like depression, show promise as animal model

by University of Texas at El PasoSergio Iñiguez, Ph.D., a professor of psychology at The University of Texas at El Paso, points out the symptoms of depression in voles to doctoral student Minerva