US company withdraws ALS drug after it fails in trial

An MRI with increased signal in the posterior part of the internal capsule which can be tracked to the motor cortex consistent with the diagnosis of ALS. Credit: Frank Gaillard/WikipediaAmylyx Pharmac

Updated on: April 06,2024

US company withdraws ALS drug after it fails in trial

An MRI with increased signal in the posterior part of the internal capsule which can be tracked to the motor cortex consistent with the diagnosis of ALS. Credit: Frank Gaillard/WikipediaAmylyx Pharmac

Updated on:April 06,2024

Mifepristone access is coming before the US Supreme Court. How safe is this abortion pill?

by LAURA UNGAR and MATTHEW PERRONEBoxes of the drug mifepristone sit on a shelf at the West Alabama Women's Center in Tuscaloosa, Ala., on March 16, 2022. On Tuesday, March 26, 2024, the U.S. Supr

Updated on: March 28,2024

Mifepristone access is coming before the US Supreme Court. How safe is this abortion pill?

by LAURA UNGAR and MATTHEW PERRONEBoxes of the drug mifepristone sit on a shelf at the West Alabama Women's Center in Tuscaloosa, Ala., on March 16, 2022. On Tuesday, March 26, 2024, the U.S. Supr

Updated on:March 28,2024

Comparing human and mouse Purkinje cells to better understand human brain complexity

by Bob Yirka , Medical XpressHuman and mouse PC morphological properties. a Morphological reconstructions of a mouse and a human PC obtained from fluorescent confocal images of postmortem fixated brai

Updated on: January 09,2024

Comparing human and mouse Purkinje cells to better understand human brain complexity

by Bob Yirka , Medical XpressHuman and mouse PC morphological properties. a Morphological reconstructions of a mouse and a human PC obtained from fluorescent confocal images of postmortem fixated brai

Updated on:January 09,2024

Researchers identify a potential target for reversing poor metabolic traits

by Brandon Chase,Massachusetts General HospitalGraphical abstract. Credit:Cell Metabolism(2023). DOI: 10.1016/j.cmet.2023.11.010During oxidative stress, excess production of reactive

Updated on: December 26,2023

Researchers identify a potential target for reversing poor metabolic traits

by Brandon Chase,Massachusetts General HospitalGraphical abstract. Credit:Cell Metabolism(2023). DOI: 10.1016/j.cmet.2023.11.010During oxidative stress, excess production of reactive

Updated on:December 26,2023

Melatonin and carcinogenesis in mice: The 50th anniversary of relationships

by Impact Journals LLCTrends in the annual numbers of publications. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.28537A new research perspective titled "Melatonin and carcinogene

Updated on: December 30,2023

Melatonin and carcinogenesis in mice: The 50th anniversary of relationships

by Impact Journals LLCTrends in the annual numbers of publications. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.28537A new research perspective titled "Melatonin and carcinogene

Updated on:December 30,2023

Lifespan increases in mice when specific brain cells are activated, study finds

by Julia Evangelou Strait,Washington University School of MedicineWith age, the researchers found that the protein Ppp1r17 tends to leave the nucleus of the neurons, and when that happens, the n

Updated on: January 09,2024

Lifespan increases in mice when specific brain cells are activated, study finds

by Julia Evangelou Strait,Washington University School of MedicineWith age, the researchers found that the protein Ppp1r17 tends to leave the nucleus of the neurons, and when that happens, the n

Updated on:January 09,2024

Study discovers novel biomarker for vascular aging and neurodegeneration

by Melissa Rohman and Olivia Dimmer,Northwestern UniversityNotch3 deficiency results in vascular dysfunction due to impaired contractility. Immunofluorescence of phosphorylated myosin light chai

Updated on: December 28,2023

Study discovers novel biomarker for vascular aging and neurodegeneration

by Melissa Rohman and Olivia Dimmer,Northwestern UniversityNotch3 deficiency results in vascular dysfunction due to impaired contractility. Immunofluorescence of phosphorylated myosin light chai

Updated on:December 28,2023

New platform streamlines epitope comparison in antibody research

by Tokyo Institute of TechnologyThe novel Epitope Binning-seq technology streamlines antibody epitope mapping and enables the simultaneous evaluation of large numbers of genetically encoded antib

Updated on: June 15,2024

New platform streamlines epitope comparison in antibody research

by Tokyo Institute of TechnologyThe novel Epitope Binning-seq technology streamlines antibody epitope mapping and enables the simultaneous evaluation of large numbers of genetically encoded antib

Updated on:June 15,2024

Improving the diagnosis of infection: A prospective study clarifies the role of an innovative metagenomic tool

byPasteur InstituteCharacteristics of samples analyzed by mNGS(A) Distribution of sample types among the 742 samples analyzed by mNGS in the present study. (B) Distribution of the sample origins

Updated on: December 30,2023

Improving the diagnosis of infection: A prospective study clarifies the role of an innovative metagenomic tool

byPasteur InstituteCharacteristics of samples analyzed by mNGS(A) Distribution of sample types among the 742 samples analyzed by mNGS in the present study. (B) Distribution of the sample origins

Updated on:December 30,2023

Researchers develop innovative and flexible method to study immune cell capabilities

byNational University of SingaporeSchematic of PAINTKiller assay. a, Preparation of affinity matrix on effector cells. Effector cells were first labeled with anti-CD45 conjugated with streptavid

Updated on: December 30,2023

Researchers develop innovative and flexible method to study immune cell capabilities

byNational University of SingaporeSchematic of PAINTKiller assay. a, Preparation of affinity matrix on effector cells. Effector cells were first labeled with anti-CD45 conjugated with streptavid

Updated on:December 30,2023

In the drive to deprescribe, heartburn drug study teaches key lessons

byUniversity of MichiganCredit: Pixabay/CC0 Public DomainWhether it's costs, safety risks, or "pill fatigue" they're trying to reduce, many health systems and clinics have star

Updated on: April 28,2024

In the drive to deprescribe, heartburn drug study teaches key lessons

byUniversity of MichiganCredit: Pixabay/CC0 Public DomainWhether it's costs, safety risks, or "pill fatigue" they're trying to reduce, many health systems and clinics have star

Updated on:April 28,2024

Targeting the racial disparity in kidney disease

Some people of West African descent face a higher risk of renal failure. New drugs based on gene research may help right the ship — if they can reach everyone who needs them.

Updated on: September 21,2024

Targeting the racial disparity in kidney disease

Some people of West African descent face a higher risk of renal failure. New drugs based on gene research may help right the ship — if they can reach everyone who needs them.

Updated on:September 21,2024