New vaccine against fatal tropical disease and potential bioterror weapon demonstrates efficacy in animal studies

by Marcus Horwitz,University of California, Los AngelesBurkholderia pseudomallei infecting a human cell. The bacteria (red) are polymerizing actin (green). Credit: Christopher T. FrenchIn a mous

Updated on: March 28,2024

New vaccine against fatal tropical disease and potential bioterror weapon demonstrates efficacy in animal studies

by Marcus Horwitz,University of California, Los AngelesBurkholderia pseudomallei infecting a human cell. The bacteria (red) are polymerizing actin (green). Credit: Christopher T. FrenchIn a mous

Updated on:March 28,2024

Vosoritide beneficial for children younger than 5 years with achondroplasia

by Elana GotkineFor children with achondroplasia, vosoritide is associated with a gain in the change in height Z score from baseline and a mild adverse event profile, according to a study published in

Updated on: January 26,2024

Vosoritide beneficial for children younger than 5 years with achondroplasia

by Elana GotkineFor children with achondroplasia, vosoritide is associated with a gain in the change in height Z score from baseline and a mild adverse event profile, according to a study published in

Updated on:January 26,2024

FoxO6-mediated ApoC3 upregulation promotes hepatic steatosis and hyperlipidemia in HFD aged rats: Study

by Impact Journals LLCAging-related serum changes in insulin resistance and lipogenesis. (A) Glucose levels, (B) insulin levels, and (C) HOMA-IR scores were determined. (D) FFA (free fatty acid), (E)

Updated on: March 28,2024

FoxO6-mediated ApoC3 upregulation promotes hepatic steatosis and hyperlipidemia in HFD aged rats: Study

by Impact Journals LLCAging-related serum changes in insulin resistance and lipogenesis. (A) Glucose levels, (B) insulin levels, and (C) HOMA-IR scores were determined. (D) FFA (free fatty acid), (E)

Updated on:March 28,2024

New species of bacteria discovered in unusual human infection

JANUARY 18, 2024byKing's College LondonHalf body FDG PET aorto – bi – iliac graft with uptake in the left periureteric region. Credit:Clinical Infection in Practice(2023). DOI: 1

Updated on: March 30,2024

New species of bacteria discovered in unusual human infection

JANUARY 18, 2024byKing's College LondonHalf body FDG PET aorto – bi – iliac graft with uptake in the left periureteric region. Credit:Clinical Infection in Practice(2023). DOI: 1

Updated on:March 30,2024

Researchers help design easy-to-open, child-resistant medicine bottle

by Abby Robinson,Georgia Institute of TechnologyEquipment used by Georgia Tech Research Institute (GTRI) product design researchers measures the forces required to open prescription medicine con

Updated on: March 24,2024

Researchers help design easy-to-open, child-resistant medicine bottle

by Abby Robinson,Georgia Institute of TechnologyEquipment used by Georgia Tech Research Institute (GTRI) product design researchers measures the forces required to open prescription medicine con

Updated on:March 24,2024

Scientists develop novel plug-and-play test to evaluate T cell immunotherapy effectiveness

byDuke-NUS Medical SchoolT cells are removed from the patient's body, engineered to fight disease, then infused back into the patient's bloodstream. At the point of infusion, and at vari

Updated on: December 04,2024

Scientists develop novel plug-and-play test to evaluate T cell immunotherapy effectiveness

byDuke-NUS Medical SchoolT cells are removed from the patient's body, engineered to fight disease, then infused back into the patient's bloodstream. At the point of infusion, and at vari

Updated on:December 04,2024

Genetic mosaicism more common than thought, study shows

Updated on: May 30,2024

Genetic mosaicism more common than thought, study shows

Updated on:May 30,2024

Poor trial results may prompt maker to pull ALS drug from market

by Robin FosterFollowing disappointing trial results, the maker of a controversial ALS drug may pull the medication off the market.In astatementissued Friday, Amylyx Pharmaceuticals said t

Updated on: March 20,2024

Poor trial results may prompt maker to pull ALS drug from market

by Robin FosterFollowing disappointing trial results, the maker of a controversial ALS drug may pull the medication off the market.In astatementissued Friday, Amylyx Pharmaceuticals said t

Updated on:March 20,2024

Unlocking the human genome: Innovative machine learning tool predicts functional consequences of genetic variants

byThe Mount Sinai HospitalLoGoFunc identifies harmful (left) and harmless (right) genetic variations in the Vasopressin V2 receptor protein using a structure predicted by AlphaFold2. This helps

Updated on: January 02,2024

Unlocking the human genome: Innovative machine learning tool predicts functional consequences of genetic variants

byThe Mount Sinai HospitalLoGoFunc identifies harmful (left) and harmless (right) genetic variations in the Vasopressin V2 receptor protein using a structure predicted by AlphaFold2. This helps

Updated on:January 02,2024

Wound healing checked in real time with electronic suture

by DGIST (Daegu Gyeongbuk Institute of Science and Technology)Schematic illustrations of (a) the Au-based fiber electrode serves as a base electrode for the working and reference electrodes, (c) the P

Updated on: August 08,2024

Wound healing checked in real time with electronic suture

by DGIST (Daegu Gyeongbuk Institute of Science and Technology)Schematic illustrations of (a) the Au-based fiber electrode serves as a base electrode for the working and reference electrodes, (c) the P

Updated on:August 08,2024

A new weapon against the super-tough C diff bacteria tested in phase-one human trial

by Laurie Fickman,University of HoustonFecal drug concentrations of omadacycline and vancomycin. Credit:The Journal of Infectious Diseases(2023). DOI: 10.1093/infdis/jiad537In a phas

Updated on: December 30,2023

A new weapon against the super-tough C diff bacteria tested in phase-one human trial

by Laurie Fickman,University of HoustonFecal drug concentrations of omadacycline and vancomycin. Credit:The Journal of Infectious Diseases(2023). DOI: 10.1093/infdis/jiad537In a phas

Updated on:December 30,2023

Researchers shed light on the molecular causes of different functions of opioid receptors

by Anne Grimm,Leipzig UniversityLigand-dependent activation of the µOR.a, Binding of agonist to the µOR activates two downstream signaling pathways: the G-protein pathway and the β-arresti

Updated on: April 28,2024

Researchers shed light on the molecular causes of different functions of opioid receptors

by Anne Grimm,Leipzig UniversityLigand-dependent activation of the µOR.a, Binding of agonist to the µOR activates two downstream signaling pathways: the G-protein pathway and the β-arresti

Updated on:April 28,2024