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Breakthroughs
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Drug found to extend survival in prostate cancer with genetic mutations

Drug found to extend survival in prostate cancer with genetic mutations

by Melissa Rohman,Northwestern University(A) rPFS for patients with a germline BRCA alteration, (B) rPFS for patients with a somatic BRCA alteration, (C) OS for patients with a germline BRCA alt

Drug found to extend survival in prostate cancer with genetic mutations

by Melissa Rohman,Northwestern University(A) rPFS for patients with a germline BRCA alteration, (B) rPFS for patients with a somatic BRCA alteration, (C) OS for patients with a germline BRCA alt
Circuit-specific gene therapy brings new hope for treatment of Parkinson's disease

Circuit-specific gene therapy brings new hope for treatment of Parkinson's disease

byChinese Academy of SciencesRetrograde AAV selectively targets D1-MSNs and rescues parkinsonian symptoms with chemogenetic modulation. Credit: SIATResearchers from the Shenzhen Institute of Adv

Circuit-specific gene therapy brings new hope for treatment of Parkinson's disease

byChinese Academy of SciencesRetrograde AAV selectively targets D1-MSNs and rescues parkinsonian symptoms with chemogenetic modulation. Credit: SIATResearchers from the Shenzhen Institute of Adv
Plant compound used in traditional medicine may help fight tuberculosis

Plant compound used in traditional medicine may help fight tuberculosis

by Katie Bohn,Pennsylvania State UniversityCredit:Journal of Ethnopharmacology(2024). DOI: 10.1016/j.jep.2024.118500A compound found in African wormwood—a plant used medicinally for

Plant compound used in traditional medicine may help fight tuberculosis

by Katie Bohn,Pennsylvania State UniversityCredit:Journal of Ethnopharmacology(2024). DOI: 10.1016/j.jep.2024.118500A compound found in African wormwood—a plant used medicinally for
New insight into the protein mutations that cause Rett syndrome

New insight into the protein mutations that cause Rett syndrome

byRockefeller UniversityWorking model for normal MeCP2 function on chromatin and its dysregulation in disease. Credit:Nature Structural & Molecular Biology(2024). DOI: 10.1038/s4

New insight into the protein mutations that cause Rett syndrome

byRockefeller UniversityWorking model for normal MeCP2 function on chromatin and its dysregulation in disease. Credit:Nature Structural & Molecular Biology(2024). DOI: 10.1038/s4
Precursor of cholesterol protects cells from ferroptosis, study finds

Precursor of cholesterol protects cells from ferroptosis, study finds

JANUARY 31, 2024byUniversity of WürzburgSpace-filling model of the Cholesterol molecule. Credit: RedAndr/WikipediaIn a groundbreaking study, a team led by Würzburg Professor José Pedro Friedmann

Precursor of cholesterol protects cells from ferroptosis, study finds

JANUARY 31, 2024byUniversity of WürzburgSpace-filling model of the Cholesterol molecule. Credit: RedAndr/WikipediaIn a groundbreaking study, a team led by Würzburg Professor José Pedro Friedmann
New therapies offer effective treatment for managing Tourette syndrome

New therapies offer effective treatment for managing Tourette syndrome

byKennedy Krieger InstituteCredit: Pixabay/CC0 Public DomainResearchers at Kennedy Krieger Institute have made significant strides in improving the lives of patients with Tourette syndrome. Thei

New therapies offer effective treatment for managing Tourette syndrome

byKennedy Krieger InstituteCredit: Pixabay/CC0 Public DomainResearchers at Kennedy Krieger Institute have made significant strides in improving the lives of patients with Tourette syndrome. Thei
A more realistic artificial skin may lead to medical advances

A more realistic artificial skin may lead to medical advances

by Laurel Hamers,University of OregonA 3D printer making the extremely fine strands used to create a new generation of artificial skin. Credit: University of OregonA new bioengineered skin model

A more realistic artificial skin may lead to medical advances

by Laurel Hamers,University of OregonA 3D printer making the extremely fine strands used to create a new generation of artificial skin. Credit: University of OregonA new bioengineered skin model
Scientists harness ultrasound for drug delivery and tissue implantation

Scientists harness ultrasound for drug delivery and tissue implantation

by Technion - Israel Institute of TechnologyUltrasound mediated polymerization of acousto-sensitive biomaterials. Credit: Small Methods (2024). DOI: 10.1002/smtd.202301197Research presents an advance

Scientists harness ultrasound for drug delivery and tissue implantation

by Technion - Israel Institute of TechnologyUltrasound mediated polymerization of acousto-sensitive biomaterials. Credit: Small Methods (2024). DOI: 10.1002/smtd.202301197Research presents an advance
SGLT-2 inhibitors show mixed results after heart attack

SGLT-2 inhibitors show mixed results after heart attack

byAmerican College of CardiologyCredit: Unsplash/CC0 Public DomainWhile the composite of death and heart failure hospitalizations was not significantly reduced, empagliflozin may help reduce hea

SGLT-2 inhibitors show mixed results after heart attack

byAmerican College of CardiologyCredit: Unsplash/CC0 Public DomainWhile the composite of death and heart failure hospitalizations was not significantly reduced, empagliflozin may help reduce hea
Drug development advances in beneficial loss-of-function mutation targets validated by human genetics

Drug development advances in beneficial loss-of-function mutation targets validated by human genetics

by Sichuan International Medical Exchange and Promotion AssociationTargets primarily include PCSK9, ANGPTL3, HSD17B13, KHK, ASGR1, GPR75, CIDEB, and INHBE. Drug types primarily include small molecules

Drug development advances in beneficial loss-of-function mutation targets validated by human genetics

by Sichuan International Medical Exchange and Promotion AssociationTargets primarily include PCSK9, ANGPTL3, HSD17B13, KHK, ASGR1, GPR75, CIDEB, and INHBE. Drug types primarily include small molecules
The genomic architecture of inherited DNA variants

The genomic architecture of inherited DNA variants

by Graciela Gutierrez,Baylor College of MedicineCredit: Pixabay/CC0 Public DomainYou have your mother's eyes and your father's smile, but genetics is much more than just what's on th

The genomic architecture of inherited DNA variants

by Graciela Gutierrez,Baylor College of MedicineCredit: Pixabay/CC0 Public DomainYou have your mother's eyes and your father's smile, but genetics is much more than just what's on th