Why clinical trials stop: Researchers find a link between genetic evidence and trial outcome

by Helena Cornu,European Molecular Biology LaboratoryHierarchical clustering of stop reason similarity based on curation from Pak et al. and 447 additional stopped trials due to COVID-19. Credit

Updated on: August 26,2024 0

Why clinical trials stop: Researchers find a link between genetic evidence and trial outcome

by Helena Cornu,European Molecular Biology LaboratoryHierarchical clustering of stop reason similarity based on curation from Pak et al. and 447 additional stopped trials due to COVID-19. Credit

Updated on:August 26,2024 0

Mechanical constraints guide spatial pattern of glioblastoma cancer stem cells

by Shanghai Jiao Tong University Journal CenterOne photo from the article titled "Mechanical constraints in tumor guide emergent spatial patterns of glioblastoma cancer stem cells" Credit: N

Updated on: April 06,2024 0

Mechanical constraints guide spatial pattern of glioblastoma cancer stem cells

by Shanghai Jiao Tong University Journal CenterOne photo from the article titled "Mechanical constraints in tumor guide emergent spatial patterns of glioblastoma cancer stem cells" Credit: N

Updated on:April 06,2024 0

Scientists develop an agent capable of selectively inhibiting the body's stress response

JANUARY 22, 2024by Daniel Meierhans,ETH ZurichThe DEGs we identified upon 2 h, and 18 h of DEX treatments in A549 cells align with the other existing RNAseq and ChIP-seq datasets. Credit:N

Updated on: March 25,2024 6

Scientists develop an agent capable of selectively inhibiting the body's stress response

JANUARY 22, 2024by Daniel Meierhans,ETH ZurichThe DEGs we identified upon 2 h, and 18 h of DEX treatments in A549 cells align with the other existing RNAseq and ChIP-seq datasets. Credit:N

Updated on:March 25,2024 6

New tool improves the search for genes that cause diseases

byUniversity of ChicagoDNA, which has a double-helix structure, can have many genetic mutations and variations. Credit: NIHA new statistical tool developed by researchers at the University of Ch

Updated on: April 26,2024 0

New tool improves the search for genes that cause diseases

byUniversity of ChicagoDNA, which has a double-helix structure, can have many genetic mutations and variations. Credit: NIHA new statistical tool developed by researchers at the University of Ch

Updated on:April 26,2024 0

Researchers report encouraging first evidence of effective new gene therapy to treat multiple sulfatase deficiency

byChildren's Hospital of PhiladelphiaCredit:Molecular Therapy(2024). DOI: 10.1016/j.ymthe.2024.08.015Researchers from Children's Hospital of Philadelphia (CHOP) have tested a

Updated on: September 14,2024 0

Researchers report encouraging first evidence of effective new gene therapy to treat multiple sulfatase deficiency

byChildren's Hospital of PhiladelphiaCredit:Molecular Therapy(2024). DOI: 10.1016/j.ymthe.2024.08.015Researchers from Children's Hospital of Philadelphia (CHOP) have tested a

Updated on:September 14,2024 0

Researchers advance understanding of Parkinson's disease

byUniversity of GalwaySchematic representation of the experimental design and procedures followed in this study. The study was designed for the region-specific and temporal characterization of t

Updated on: April 28,2024 0

Researchers advance understanding of Parkinson's disease

byUniversity of GalwaySchematic representation of the experimental design and procedures followed in this study. The study was designed for the region-specific and temporal characterization of t

Updated on:April 28,2024 0

Researchers develop new tool to aid processing of spatial transcriptomic data

by Children's Hospital of PhiladelphiaThe network architecture of dependency-aware deep generative models. Credit:Nature Methods(2024). DOI: 10.1038/s41592-024-02257-yResearchers

Updated on: June 15,2024 6

Researchers develop new tool to aid processing of spatial transcriptomic data

by Children's Hospital of PhiladelphiaThe network architecture of dependency-aware deep generative models. Credit:Nature Methods(2024). DOI: 10.1038/s41592-024-02257-yResearchers

Updated on:June 15,2024 6

Researchers uncover genetic factors for severe Lassa fever

by Allessandra DiCorato,Broad Institute of MIT and HarvardScanning electron image of the Lassa virus budding off a cell. Credit: NIAID Integrated Research Facility (IRF) in Fort Detrick, Marylan

Updated on: March 13,2024 6

Researchers uncover genetic factors for severe Lassa fever

by Allessandra DiCorato,Broad Institute of MIT and HarvardScanning electron image of the Lassa virus budding off a cell. Credit: NIAID Integrated Research Facility (IRF) in Fort Detrick, Marylan

Updated on:March 13,2024 6

Drugs of the future will be easier and faster to make, thanks to mRNA—after researchers work out a few remaining kinks

JANUARY 5, 2024by Li Li,The ConversationThis is a computer graphic of an RNA molecule. Credit: Richard Feldmann/WikipediaVaccines have been reliably and affordably protecting people from disease

Updated on: March 30,2024 3

Drugs of the future will be easier and faster to make, thanks to mRNA—after researchers work out a few remaining kinks

JANUARY 5, 2024by Li Li,The ConversationThis is a computer graphic of an RNA molecule. Credit: Richard Feldmann/WikipediaVaccines have been reliably and affordably protecting people from disease

Updated on:March 30,2024 3

FDA Approves Lymphir: A New Hope for CTCL Patients

The U.S. Food and Drug Administration (FDA) had approved Lymphir (denileukin diftitox-cxdl), a novel immunotherapy for the treatment of relapsed or refractory cutaneous T-cell lymphoma (CTCL) after at least one prior systemic therapy.

Updated on: August 12,2024 0

FDA Approves Lymphir: A New Hope for CTCL Patients

The U.S. Food and Drug Administration (FDA) had approved Lymphir (denileukin diftitox-cxdl), a novel immunotherapy for the treatment of relapsed or refractory cutaneous T-cell lymphoma (CTCL) after at least one prior systemic therapy.

Updated on:August 12,2024 0

Aspirin cuts liver fat in clinical trial

by Tracy Hampton,Harvard UniversityCredit: Pixabay/CC0 Public DomainThe most common chronic liver disease—metabolic dysfunction–associated steatotic liver disease (MASLD)—is characterized by an

Updated on: March 28,2024 0

Aspirin cuts liver fat in clinical trial

by Tracy Hampton,Harvard UniversityCredit: Pixabay/CC0 Public DomainThe most common chronic liver disease—metabolic dysfunction–associated steatotic liver disease (MASLD)—is characterized by an

Updated on:March 28,2024 0

How to make mRNA therapeutics safe from the start

FEBRUARY 28, 2024by Cynthia McCormick Hibbert,Northeastern UniversityScientists eager to harness mRNA technology to fight cancer and more need to find ways to test early for safety, Northeastern

Updated on: March 25,2024 6

How to make mRNA therapeutics safe from the start

FEBRUARY 28, 2024by Cynthia McCormick Hibbert,Northeastern UniversityScientists eager to harness mRNA technology to fight cancer and more need to find ways to test early for safety, Northeastern

Updated on:March 25,2024 6