Study identifies novel mechanism of glucose sensing by adipocytes in regulating thermogenesis and energy metabolism

by Liu Jia,Chinese Academy of SciencesThe proposed model for glucose sensing via CREBZF in the regulation of thermogenesis and energy homeostasis in adipose tissues. Targeting CREBZF may provide

Updated on: April 28,2024

Study identifies novel mechanism of glucose sensing by adipocytes in regulating thermogenesis and energy metabolism

by Liu Jia,Chinese Academy of SciencesThe proposed model for glucose sensing via CREBZF in the regulation of thermogenesis and energy homeostasis in adipose tissues. Targeting CREBZF may provide

Updated on:April 28,2024

Systematic review links outdoor air pollution to differences in children's brains

by Alex Russell,UC DavisCredit: Pixabay/CC0 Public DomainOutdoor air pollution from power plants, fires and cars continues to degrade human, animal and environmental health around the globe. New

Updated on: October 17,2024

Systematic review links outdoor air pollution to differences in children's brains

by Alex Russell,UC DavisCredit: Pixabay/CC0 Public DomainOutdoor air pollution from power plants, fires and cars continues to degrade human, animal and environmental health around the globe. New

Updated on:October 17,2024

A step closer to treatment for severe bacterial infections and sepsis

JANUARY 10, 2024byLund UniversityThe illustration depicts how the researchers' peptide treatment (pink) binds to both receptors that can detect bacterial substances (green) and to bacterial

Updated on: March 25,2024

A step closer to treatment for severe bacterial infections and sepsis

JANUARY 10, 2024byLund UniversityThe illustration depicts how the researchers' peptide treatment (pink) binds to both receptors that can detect bacterial substances (green) and to bacterial

Updated on:March 25,2024

Research suggests fine-tuning of specific excitatory synapse traits could lead to new brain disease treatments

by DGIST (Daegu Gyeongbuk Institute of Science and Technology)Profiling of LAR-RPTP microexon expression repertoires by targeted deep RNA sequencing Credit:Nature Communications(2024). DOI

Updated on: March 30,2024

Research suggests fine-tuning of specific excitatory synapse traits could lead to new brain disease treatments

by DGIST (Daegu Gyeongbuk Institute of Science and Technology)Profiling of LAR-RPTP microexon expression repertoires by targeted deep RNA sequencing Credit:Nature Communications(2024). DOI

Updated on:March 30,2024

Recommendations to facilitate design and implementation of clinical pharmacogenomic DPYD genotyping assays

by Association for Molecular PathologyCredit: Pixabay/CC0 Public DomainThe Association for Molecular Pathology (AMP) has published consensus recommendations to aid in the design and validation of clin

Updated on: July 23,2024

Recommendations to facilitate design and implementation of clinical pharmacogenomic DPYD genotyping assays

by Association for Molecular PathologyCredit: Pixabay/CC0 Public DomainThe Association for Molecular Pathology (AMP) has published consensus recommendations to aid in the design and validation of clin

Updated on:July 23,2024

Targeting the mRNA of 'undruggable' proteins in the fight against Parkinson's disease

JANUARY 8, 2024REPORTby Justin Jackson , Medical XpressCredit: Pixabay/CC0 Public DomainResearchers at the Scripps Research Institute, Florida, have developed a new method to counteract α-synucl

Updated on: March 30,2024

Targeting the mRNA of 'undruggable' proteins in the fight against Parkinson's disease

JANUARY 8, 2024REPORTby Justin Jackson , Medical XpressCredit: Pixabay/CC0 Public DomainResearchers at the Scripps Research Institute, Florida, have developed a new method to counteract α-synucl

Updated on:March 30,2024

New approach to the design of therapies that enhance the effect of cholesterol-lowering drugs

FEBRUARY 1, 2024by Centro Nacional de Investigaciones Cardiovasculares Carlos III (F.S.P.)Graphical summary. Credit:Nature Cardiovascular Research(2024). DOI: 10.1038/s44161-023-00412-wA r

Updated on: March 25,2024

New approach to the design of therapies that enhance the effect of cholesterol-lowering drugs

FEBRUARY 1, 2024by Centro Nacional de Investigaciones Cardiovasculares Carlos III (F.S.P.)Graphical summary. Credit:Nature Cardiovascular Research(2024). DOI: 10.1038/s44161-023-00412-wA r

Updated on:March 25,2024

Coronary sinus reducer relieves angina, but how it works remains unclear

byAmerican College of CardiologyCredit: Towfiqu barbhuiya from PexelsPeople with chronic chest pain who received a coronary sinus reducer (CSR)—a stent thought to increase the amount of oxygen-r

Updated on: April 28,2024

Coronary sinus reducer relieves angina, but how it works remains unclear

byAmerican College of CardiologyCredit: Towfiqu barbhuiya from PexelsPeople with chronic chest pain who received a coronary sinus reducer (CSR)—a stent thought to increase the amount of oxygen-r

Updated on:April 28,2024

Study discovers how a magnesium cellular transport 'pump' plays a vital role in cardiac function

by Steven Lee,University of Texas Health Science Center at San AntonioCredit:Molecular Cell(2024). DOI: 10.1016/j.molcel.2024.02.033Magnesium is a mineral critical to a wide range of

Updated on: March 30,2024

Study discovers how a magnesium cellular transport 'pump' plays a vital role in cardiac function

by Steven Lee,University of Texas Health Science Center at San AntonioCredit:Molecular Cell(2024). DOI: 10.1016/j.molcel.2024.02.033Magnesium is a mineral critical to a wide range of

Updated on:March 30,2024

Biological engineers discover why a promising drug failed in clinical trials

by Anne Trafton,Massachusetts Institute of TechnologyRheumatoid arthritis, which afflicts more than 1 million Americans, is an autoimmune disorder that produces swollen and painful joints, prima

Updated on: May 08,2024

Biological engineers discover why a promising drug failed in clinical trials

by Anne Trafton,Massachusetts Institute of TechnologyRheumatoid arthritis, which afflicts more than 1 million Americans, is an autoimmune disorder that produces swollen and painful joints, prima

Updated on:May 08,2024

Innovative therapies for ischemic stroke: Novel bicarbonate-sensing G protein-coupled receptor shows promise

FEBRUARY 27, 2024by Juntendo University Research Promotion CenterGPR30 in brain microvasculature responds to bicarbonate, and its deficiency protects against ischemia-reperfusion injury, reducing neur

Updated on: March 25,2024

Innovative therapies for ischemic stroke: Novel bicarbonate-sensing G protein-coupled receptor shows promise

FEBRUARY 27, 2024by Juntendo University Research Promotion CenterGPR30 in brain microvasculature responds to bicarbonate, and its deficiency protects against ischemia-reperfusion injury, reducing neur

Updated on:March 25,2024

Trials shows bimekizumab response durable at four years for moderate-to-severe psoriasis

by Tina BrownPatients with psoriasis treated with bimekizumab rapidly achieve high levels of clinical and health-related quality-of-life responses that are durable at four years, according to research

Updated on: March 28,2024

Trials shows bimekizumab response durable at four years for moderate-to-severe psoriasis

by Tina BrownPatients with psoriasis treated with bimekizumab rapidly achieve high levels of clinical and health-related quality-of-life responses that are durable at four years, according to research

Updated on:March 28,2024