Researchers find genetic variant coding for tubulin protein that may be partially responsible for left-handedness

by Bob Yirka , Medical XpressExome-wide, gene-based association testing in 38,043 left-handed and 313,271 right-handed individuals, based on rare protein-altering variants. Top: the strict variant set

Updated on: April 06,2024

Researchers find genetic variant coding for tubulin protein that may be partially responsible for left-handedness

by Bob Yirka , Medical XpressExome-wide, gene-based association testing in 38,043 left-handed and 313,271 right-handed individuals, based on rare protein-altering variants. Top: the strict variant set

Updated on:April 06,2024

Study with over 11,000 individuals of African descent finds genetic variants linked to glaucoma

byCell PressDiscovery of known and previously undescribed loci from the discovery mega-analysis of African ancestry individuals. Credit: Cell/Verma et al.Glaucoma is the leading cause of irrever

Updated on: March 14,2024

Study with over 11,000 individuals of African descent finds genetic variants linked to glaucoma

byCell PressDiscovery of known and previously undescribed loci from the discovery mega-analysis of African ancestry individuals. Credit: Cell/Verma et al.Glaucoma is the leading cause of irrever

Updated on:March 14,2024

The dual role of well-known protein sheds light on Parkinson's disease mechanisms

NOVEMBER 6, 2023by Lisbeth Heilesen,Aarhus UniversityNew research from Aarhus University with international collaborations has revealed that natural aSN activates an important calcium pump in th

Updated on: March 30,2024

The dual role of well-known protein sheds light on Parkinson's disease mechanisms

NOVEMBER 6, 2023by Lisbeth Heilesen,Aarhus UniversityNew research from Aarhus University with international collaborations has revealed that natural aSN activates an important calcium pump in th

Updated on:March 30,2024

Researchers identify potential way to treat genetic epilepsy by replacing 'lost' enzyme

byThe Francis Crick InstituteCredit: Pixabay/CC0 Public DomainScientists at the Francis Crick Institute have found a new treatment target for CDKL5 deficiency disorder (CDD), one of the most com

Updated on: March 13,2024

Researchers identify potential way to treat genetic epilepsy by replacing 'lost' enzyme

byThe Francis Crick InstituteCredit: Pixabay/CC0 Public DomainScientists at the Francis Crick Institute have found a new treatment target for CDKL5 deficiency disorder (CDD), one of the most com

Updated on:March 13,2024

Study identifies molecular mechanisms of rare neurodevelopmental disorder

by Melissa Rohman,Northwestern UniversityNeurons cultured for 65 days from healthy cells and those containing the PACS1 syndrome variant both have complex morphology and express neuronal microtu

Updated on: March 13,2024

Study identifies molecular mechanisms of rare neurodevelopmental disorder

by Melissa Rohman,Northwestern UniversityNeurons cultured for 65 days from healthy cells and those containing the PACS1 syndrome variant both have complex morphology and express neuronal microtu

Updated on:March 13,2024

Researchers identify peptides produced by the proteasome that degrade damaged proteins

FEBRUARY 14, 2024by Carmen Rotte,Max Planck SocietyUsing innovative computer programs and biochemical experiments, researchers identified and quantified fragments that the cellular garbage dispo

Updated on: March 28,2024

Researchers identify peptides produced by the proteasome that degrade damaged proteins

FEBRUARY 14, 2024by Carmen Rotte,Max Planck SocietyUsing innovative computer programs and biochemical experiments, researchers identified and quantified fragments that the cellular garbage dispo

Updated on:March 28,2024

Research uncovers mechanism behind stubborn memories

BRAIN HEALTHMEDICAL SCIENCESMENTAL HEALTHNEUROSCIENCERESEARCH18 January 2024Researchers from the Medical Research Council Brain Network Dynamics Unit at the University of Oxford and the Nuffield Depar

Updated on: March 11,2024

Research uncovers mechanism behind stubborn memories

BRAIN HEALTHMEDICAL SCIENCESMENTAL HEALTHNEUROSCIENCERESEARCH18 January 2024Researchers from the Medical Research Council Brain Network Dynamics Unit at the University of Oxford and the Nuffield Depar

Updated on:March 11,2024

First health care device powered by body heat made possible by liquid based metals

by Kaitlyn Landram,Carnegie Mellon University Mechanical EngineeringCredit: Carnegie Mellon Unviersity, College of EngineeringIn the age of technology everywhere, we are all too familiar with th

Updated on: July 23,2024

First health care device powered by body heat made possible by liquid based metals

by Kaitlyn Landram,Carnegie Mellon University Mechanical EngineeringCredit: Carnegie Mellon Unviersity, College of EngineeringIn the age of technology everywhere, we are all too familiar with th

Updated on:July 23,2024

Study: PR55α-controlled PP2A inhibits p16 expression and blocks cellular senescence induction

by Impact Journals LLCPR55α level is much lower in human normal tissue specimens of older individuals compared to younger individuals and inversely correlates with p16 levels. Human normal tissue spec

Updated on: March 27,2024

Study: PR55α-controlled PP2A inhibits p16 expression and blocks cellular senescence induction

by Impact Journals LLCPR55α level is much lower in human normal tissue specimens of older individuals compared to younger individuals and inversely correlates with p16 levels. Human normal tissue spec

Updated on:March 27,2024

Examining the potential of the common bovine as a potential therapeutic research model

by Tom Fleischman,Cornell UniversityGraphical Abstract. Credit:iScience(2024). DOI: 10.1016/j.isci.2024.108886Research involving animal models—for purposes such as developing new vac

Updated on: March 30,2024

Examining the potential of the common bovine as a potential therapeutic research model

by Tom Fleischman,Cornell UniversityGraphical Abstract. Credit:iScience(2024). DOI: 10.1016/j.isci.2024.108886Research involving animal models—for purposes such as developing new vac

Updated on:March 30,2024

Experimental compound extends life in amyotrophic lateral sclerosis mouse model

FEBRUARY 6, 2024byUT Southwestern Medical CenterMAP4K interactome and the effect on RANGAP1 subcellular distribution.AWestern-blotting analysis of proteins after proximity labeling i

Updated on: March 25,2024

Experimental compound extends life in amyotrophic lateral sclerosis mouse model

FEBRUARY 6, 2024byUT Southwestern Medical CenterMAP4K interactome and the effect on RANGAP1 subcellular distribution.AWestern-blotting analysis of proteins after proximity labeling i

Updated on:March 25,2024

Familial Alzheimer's disease transferred via bone marrow transplant in mice

byCell PressA painting representing Alzheimer's transmissibility as reported in thisStem Cell Reportsstudy. Credit: Chaahat SinghFamilial Alzheimer's disease can be transferr

Updated on: March 30,2024

Familial Alzheimer's disease transferred via bone marrow transplant in mice

byCell PressA painting representing Alzheimer's transmissibility as reported in thisStem Cell Reportsstudy. Credit: Chaahat SinghFamilial Alzheimer's disease can be transferr

Updated on:March 30,2024