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Study identifies epigenetic 'switches' that regulate the developmental trajectories of single cells

Study identifies epigenetic 'switches' that regulate the developmental trajectories of single cells

by Ingrid Fadelli , Medical XpressAnalysis of the developmental cell atlas. a, Workflow to obtain single-cell RNA (scRNA) expression and CUT&Tag data for three histone modifications (H3K27me3, H3K

Study identifies epigenetic 'switches' that regulate the developmental trajectories of single cells

by Ingrid Fadelli , Medical XpressAnalysis of the developmental cell atlas. a, Workflow to obtain single-cell RNA (scRNA) expression and CUT&Tag data for three histone modifications (H3K27me3, H3K
Researchers identify peptides produced by the proteasome that degrade damaged proteins

Researchers identify peptides produced by the proteasome that degrade damaged proteins

FEBRUARY 14, 2024by Carmen Rotte,Max Planck SocietyUsing innovative computer programs and biochemical experiments, researchers identified and quantified fragments that the cellular garbage dispo

Researchers identify peptides produced by the proteasome that degrade damaged proteins

FEBRUARY 14, 2024by Carmen Rotte,Max Planck SocietyUsing innovative computer programs and biochemical experiments, researchers identified and quantified fragments that the cellular garbage dispo
New technique for revealing genetic repeats yields surprising insights into Huntington's disease

New technique for revealing genetic repeats yields surprising insights into Huntington's disease

byRockefeller UniversityCredit:Neuron(2024). DOI: 10.1016/j.neuron.2023.12.009Neurodegenerative diseases are among the most complex human ailments, and their exact causes and mechani

New technique for revealing genetic repeats yields surprising insights into Huntington's disease

byRockefeller UniversityCredit:Neuron(2024). DOI: 10.1016/j.neuron.2023.12.009Neurodegenerative diseases are among the most complex human ailments, and their exact causes and mechani
Danish study could pave the way for better diagnosis of rare genetic diseases

Danish study could pave the way for better diagnosis of rare genetic diseases

byAarhus UniversityGraphical abstract. Credit:The American Journal of Human Genetics(2024). DOI: 10.1016/j.ajhg.2023.12.024There are over 7,000 different rare genetic diseases, and o

Danish study could pave the way for better diagnosis of rare genetic diseases

byAarhus UniversityGraphical abstract. Credit:The American Journal of Human Genetics(2024). DOI: 10.1016/j.ajhg.2023.12.024There are over 7,000 different rare genetic diseases, and o
Zebrafish's eye muscles give hope for people with muscular dystrophy diseases

Zebrafish's eye muscles give hope for people with muscular dystrophy diseases

by Claes Björnberg,Umea UniversityAxon and NMJ integrity is partially rescued by overexpression of fhl2b in trunk muscle of 5 dpf dmd-/-zebrafish larvae. Credit: https://umu.diva-portal.or

Zebrafish's eye muscles give hope for people with muscular dystrophy diseases

by Claes Björnberg,Umea UniversityAxon and NMJ integrity is partially rescued by overexpression of fhl2b in trunk muscle of 5 dpf dmd-/-zebrafish larvae. Credit: https://umu.diva-portal.or
Transmission risk of multidrug-resistant bacteria appears highest in hospital sinks

Transmission risk of multidrug-resistant bacteria appears highest in hospital sinks

by Association for Professionals in Infection ControlCredit: CC0 Public DomainA newstudypublished today in theAmerican Journal of Infection Control (AJIC)reports the infection

Transmission risk of multidrug-resistant bacteria appears highest in hospital sinks

by Association for Professionals in Infection ControlCredit: CC0 Public DomainA newstudypublished today in theAmerican Journal of Infection Control (AJIC)reports the infection
Study uses metabolomics to identify novel diagnostic markers for chronic obstructive pulmonary disease

Study uses metabolomics to identify novel diagnostic markers for chronic obstructive pulmonary disease

by Cactus CommunicationsAlterations in metabolism of lipids, amino acids, glucose, nucleotides, and pulmonary and gut microbiome play a crucial role in COPD development. These metabolites have great p

Study uses metabolomics to identify novel diagnostic markers for chronic obstructive pulmonary disease

by Cactus CommunicationsAlterations in metabolism of lipids, amino acids, glucose, nucleotides, and pulmonary and gut microbiome play a crucial role in COPD development. These metabolites have great p
Study shows that the way the brain learns is different from the way that artificial intelligence systems learn

Study shows that the way the brain learns is different from the way that artificial intelligence systems learn

ARTIFICIAL INTELLIGENCEMEDICAL SCIENCESNEUROSCIENCERESEARCHSCIENCEResearchers from theMRC Brain Network Dynamics Unit and Oxford University’sDepartment of Computer Sciencehave set ou

Study shows that the way the brain learns is different from the way that artificial intelligence systems learn

ARTIFICIAL INTELLIGENCEMEDICAL SCIENCESNEUROSCIENCERESEARCHSCIENCEResearchers from theMRC Brain Network Dynamics Unit and Oxford University’sDepartment of Computer Sciencehave set ou
Research harnesses machine learning and imaging to give insight into stem cell behavior

Research harnesses machine learning and imaging to give insight into stem cell behavior

by Greta Harrison,University of Southern CaliforniaSingle hematopoietic stem cells dividing metabolically (m) symmetrically and asymmetrically, measured by the research team’s imaging technique.

Research harnesses machine learning and imaging to give insight into stem cell behavior

by Greta Harrison,University of Southern CaliforniaSingle hematopoietic stem cells dividing metabolically (m) symmetrically and asymmetrically, measured by the research team’s imaging technique.
Novel pre-clinical models help advance therapeutic development for antibiotic-resistant bacterial infections

Novel pre-clinical models help advance therapeutic development for antibiotic-resistant bacterial infections

by Agency for Science, Technology and Research (A*STAR), SingaporeGraphical abstract. Credit:iScience(2024). DOI: 10.1016/j.isci.2024.108875The A*STAR Infectious Diseases Labs (A*STAR

Novel pre-clinical models help advance therapeutic development for antibiotic-resistant bacterial infections

by Agency for Science, Technology and Research (A*STAR), SingaporeGraphical abstract. Credit:iScience(2024). DOI: 10.1016/j.isci.2024.108875The A*STAR Infectious Diseases Labs (A*STAR
Chemical and computational advances enable 2D proteomics measurements of spatial signals

Chemical and computational advances enable 2D proteomics measurements of spatial signals

FEBRUARY 5, 2024byPacific Northwest National LaboratoryMicroPOTS is a chip-based approach developed by Pacific Northwest National Laboratory that allows sample processing in a microliter droplet

Chemical and computational advances enable 2D proteomics measurements of spatial signals

FEBRUARY 5, 2024byPacific Northwest National LaboratoryMicroPOTS is a chip-based approach developed by Pacific Northwest National Laboratory that allows sample processing in a microliter droplet