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Medical research
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Mouse study finds birth coincides with rapid changes in gene activity

Mouse study finds birth coincides with rapid changes in gene activity

FEBRUARY 15, 2024byUniversity of Washington School of MedicineTranscriptional heterogeneity in the posterior embryo during early somitogenesis.a, Re-embedded 3D UMAP of 121,118 cells from

Mouse study finds birth coincides with rapid changes in gene activity

FEBRUARY 15, 2024byUniversity of Washington School of MedicineTranscriptional heterogeneity in the posterior embryo during early somitogenesis.a, Re-embedded 3D UMAP of 121,118 cells from
Drug shows promise for slowing progression of rare, painful genetic disease

Drug shows promise for slowing progression of rare, painful genetic disease

by National Institutes of HealthCredit: CC0 Public DomainA drug used to treat certain bone diseases shows promise for slowing the progression of a rare, painful genetic condition that causes exce

Drug shows promise for slowing progression of rare, painful genetic disease

by National Institutes of HealthCredit: CC0 Public DomainA drug used to treat certain bone diseases shows promise for slowing the progression of a rare, painful genetic condition that causes exce
New study shows a role for cholesterol in pain perception

New study shows a role for cholesterol in pain perception

FEBRUARY 27, 2024byUniversity of FloridaA cell membrane is illustrated to show the surface in red. Blue objects are proteins, including ion channels, which can send electrical impulses into cell

New study shows a role for cholesterol in pain perception

FEBRUARY 27, 2024byUniversity of FloridaA cell membrane is illustrated to show the surface in red. Blue objects are proteins, including ion channels, which can send electrical impulses into cell
Re-engineered antibiotic shows potential for treatment of drug-resistant bacteria

Re-engineered antibiotic shows potential for treatment of drug-resistant bacteria

by St. Jude Children's Research HospitalResearchers led by St. Jude Children's Research Hospital scientists have developed a second-generation antibiotic that shows early effectiveness ag

Re-engineered antibiotic shows potential for treatment of drug-resistant bacteria

by St. Jude Children's Research HospitalResearchers led by St. Jude Children's Research Hospital scientists have developed a second-generation antibiotic that shows early effectiveness ag
Researchers are using RNA in a new approach to fight HIV

Researchers are using RNA in a new approach to fight HIV

FEBRUARY 20, 2024byUniversity of WaterlooGraphical abstract. Credit:Journal of Controlled Release(2024). DOI: 10.1016/j.jconrel.2023.12.043Society learned about the value of mRNA dur

Researchers are using RNA in a new approach to fight HIV

FEBRUARY 20, 2024byUniversity of WaterlooGraphical abstract. Credit:Journal of Controlled Release(2024). DOI: 10.1016/j.jconrel.2023.12.043Society learned about the value of mRNA dur
Study identifies molecular mechanisms of rare neurodevelopmental disorder

Study identifies molecular mechanisms of rare neurodevelopmental disorder

by Melissa Rohman,Northwestern UniversityNeurons cultured for 65 days from healthy cells and those containing the PACS1 syndrome variant both have complex morphology and express neuronal microtu

Study identifies molecular mechanisms of rare neurodevelopmental disorder

by Melissa Rohman,Northwestern UniversityNeurons cultured for 65 days from healthy cells and those containing the PACS1 syndrome variant both have complex morphology and express neuronal microtu
New genome editing tools unlock possibilities for precision medicine

New genome editing tools unlock possibilities for precision medicine

by Stephan Wiegand,Dresden University of TechnologyDesign of ZFDs for the loxF8 genomic locus. a, Genomic sequences flanking loxF8. Binding sites of the designed ZFDs upstream (orange, ZFL1–2) a

New genome editing tools unlock possibilities for precision medicine

by Stephan Wiegand,Dresden University of TechnologyDesign of ZFDs for the loxF8 genomic locus. a, Genomic sequences flanking loxF8. Binding sites of the designed ZFDs upstream (orange, ZFL1–2) a
Protein production glitches in Huntington's disease revealed

Protein production glitches in Huntington's disease revealed

by Shafaq Zia,Whitehead Institute for Biomedical ResearchRNAs with expanded CAG repeats (red) form regions of high concentration in the nucleus (blue) of a cell. Credit: Rachel Anderson/ Whitehe

Protein production glitches in Huntington's disease revealed

by Shafaq Zia,Whitehead Institute for Biomedical ResearchRNAs with expanded CAG repeats (red) form regions of high concentration in the nucleus (blue) of a cell. Credit: Rachel Anderson/ Whitehe
Meta-analysis of ACE inhibitor–induced angioedema identifies novel risk locus in genome

Meta-analysis of ACE inhibitor–induced angioedema identifies novel risk locus in genome

by Petra Sandow,University Hospital BonnManhattan plot of the metaEURanalysis. The −log10association P values (vertical axis) for all variants of the metaEURanalysis against th

Meta-analysis of ACE inhibitor–induced angioedema identifies novel risk locus in genome

by Petra Sandow,University Hospital BonnManhattan plot of the metaEURanalysis. The −log10association P values (vertical axis) for all variants of the metaEURanalysis against th
Study identifies factors that affect antibiotic prescribing for acne

Study identifies factors that affect antibiotic prescribing for acne

by Elana GotkineMultiple salient factors affect long-term antibiotic prescribing practices for acne, according to a studypublishedinJAMA Dermatology.Ronnie A. Festok, from the Emory

Study identifies factors that affect antibiotic prescribing for acne

by Elana GotkineMultiple salient factors affect long-term antibiotic prescribing practices for acne, according to a studypublishedinJAMA Dermatology.Ronnie A. Festok, from the Emory
A closed-loop drug-delivery system could improve chemotherapy

A closed-loop drug-delivery system could improve chemotherapy

by Anne Trafton,Massachusetts Institute of TechnologyTo make chemotherapy dosing more accurate, MIT engineers have come up with a way to continuously measure how much drug is in the patient’s sy

A closed-loop drug-delivery system could improve chemotherapy

by Anne Trafton,Massachusetts Institute of TechnologyTo make chemotherapy dosing more accurate, MIT engineers have come up with a way to continuously measure how much drug is in the patient’s sy
Researchers identify potential way to treat genetic epilepsy by replacing 'lost' enzyme

Researchers identify potential way to treat genetic epilepsy by replacing 'lost' enzyme

byThe Francis Crick InstituteCredit: Pixabay/CC0 Public DomainScientists at the Francis Crick Institute have found a new treatment target for CDKL5 deficiency disorder (CDD), one of the most com

Researchers identify potential way to treat genetic epilepsy by replacing 'lost' enzyme

byThe Francis Crick InstituteCredit: Pixabay/CC0 Public DomainScientists at the Francis Crick Institute have found a new treatment target for CDKL5 deficiency disorder (CDD), one of the most com