Trial begins of nasal vaccine for Alzheimer's disease

(HealthDay)—The first human clinical trial of a nasal vaccine to slow the progression of Alzheimer's disease is set to begin after nearly 20 years of research.This is a "remarkable milestone,

Updated on: April 02,2024 16

Trial begins of nasal vaccine for Alzheimer's disease

(HealthDay)—The first human clinical trial of a nasal vaccine to slow the progression of Alzheimer's disease is set to begin after nearly 20 years of research.This is a "remarkable milestone,

Updated on:April 02,2024 16

Alzheimer's disease – don't give up on plaque-busting drugs just yet

by Davide Bruno,The ConversationCredit: AI-generated imageAlzheimer's disease is associated with abuild-up of plaquesin the brain called amyloid beta. These plaques are thought t

Updated on: April 02,2024 18

Alzheimer's disease – don't give up on plaque-busting drugs just yet

by Davide Bruno,The ConversationCredit: AI-generated imageAlzheimer's disease is associated with abuild-up of plaquesin the brain called amyloid beta. These plaques are thought t

Updated on:April 02,2024 18

Tau PET: A window into the future of Alzheimer's patients

by University of GenevaTau imaging with 18F-Flortaucipir PET in Alzheimer’s disease. The figure shows a prototypical tau accumulation pattern, obtained by comparing tau load of patients with Alzh

Updated on: April 02,2024 10

Tau PET: A window into the future of Alzheimer's patients

by University of GenevaTau imaging with 18F-Flortaucipir PET in Alzheimer’s disease. The figure shows a prototypical tau accumulation pattern, obtained by comparing tau load of patients with Alzh

Updated on:April 02,2024 10

Alzheimer's disease: Reduced signals in the brain's forgotten cells

by University of OsloAssociate Professor Rune Enger at the Institute of Basic Medical Sciences at the University of Oslo. Credit: Cecilie Bakken Høstmark, UiOAlzheimer's disease is associated

Updated on: April 02,2024 18

Alzheimer's disease: Reduced signals in the brain's forgotten cells

by University of OsloAssociate Professor Rune Enger at the Institute of Basic Medical Sciences at the University of Oslo. Credit: Cecilie Bakken Høstmark, UiOAlzheimer's disease is associated

Updated on:April 02,2024 18

New information on the pathological mechanisms of Alzheimer's disease

by University of HelsinkiImmunoelectron microscopy image of accumulated tau protein on cell membrane. Credit: Henri HuttunenResearchers at the University of Helsinki have discovered a mechanism b

Updated on: April 02,2024 18

New information on the pathological mechanisms of Alzheimer's disease

by University of HelsinkiImmunoelectron microscopy image of accumulated tau protein on cell membrane. Credit: Henri HuttunenResearchers at the University of Helsinki have discovered a mechanism b

Updated on:April 02,2024 18

Study reveals a driver of brain cell damage in neurodegeneration

by Leah Eisenstadt,Broad Institute of MIT and HarvardA section of brain from a mouse model of neurodegeneration, showing a control protein in green, Nptx2 in red, and glial cells in white. Boost

Updated on: April 02,2024 12

Study reveals a driver of brain cell damage in neurodegeneration

by Leah Eisenstadt,Broad Institute of MIT and HarvardA section of brain from a mouse model of neurodegeneration, showing a control protein in green, Nptx2 in red, and glial cells in white. Boost

Updated on:April 02,2024 12

Alzheimer's: Protective immune cells active decades before symptom onset

by German Center for Neurodegenerative DiseasesCredit: Pixabay/CC0 Public DomainIn individuals with a genetic predisposition to Alzheimer's disease, the immune cells of the brain—the "mi

Updated on: April 02,2024 19

Alzheimer's: Protective immune cells active decades before symptom onset

by German Center for Neurodegenerative DiseasesCredit: Pixabay/CC0 Public DomainIn individuals with a genetic predisposition to Alzheimer's disease, the immune cells of the brain—the "mi

Updated on:April 02,2024 19

The danger of Z-drugs for dementia patients

by University of East AngliaCredit: CC0 Public DomainStrong sleeping pills known as 'Z-drugs' are linked with an increased risk of falls, fractures and stroke among people with dementia—a

Updated on: April 02,2024 15

The danger of Z-drugs for dementia patients

by University of East AngliaCredit: CC0 Public DomainStrong sleeping pills known as 'Z-drugs' are linked with an increased risk of falls, fractures and stroke among people with dementia—a

Updated on:April 02,2024 15

Tau hot spots open new avenues of discovery into dementia

by Queensland Brain InstituteRepresentative diffraction-limited image of a neuroblastoma cell expressing Tau-mEos3.2 molecules acquired in the green channel before single-molecule imaging. Credit: Dr

Updated on: April 02,2024 20

Tau hot spots open new avenues of discovery into dementia

by Queensland Brain InstituteRepresentative diffraction-limited image of a neuroblastoma cell expressing Tau-mEos3.2 molecules acquired in the green channel before single-molecule imaging. Credit: Dr

Updated on:April 02,2024 20

Solanezumab does not slow cognitive decline in preclinical Alzheimer disease

by Elana GotkineFor patients with preclinical Alzheimer disease, solanezumab does not slow cognitive decline, according to a study published online July 17 in theNew England Journal of Medicine&

Updated on: April 02,2024 19

Solanezumab does not slow cognitive decline in preclinical Alzheimer disease

by Elana GotkineFor patients with preclinical Alzheimer disease, solanezumab does not slow cognitive decline, according to a study published online July 17 in theNew England Journal of Medicine&

Updated on:April 02,2024 19

Tau-regulating protein identified as a promising target for developing Alzheimer's disease treatment

by Perelman School of Medicine at the University of PennsylvaniaIndividuals with Alzheimer’s disease (AD) have increased neurofibrillary tangles (NFTs) of tau proteins but reduced TRIM11, as show

Updated on: April 02,2024 19

Tau-regulating protein identified as a promising target for developing Alzheimer's disease treatment

by Perelman School of Medicine at the University of PennsylvaniaIndividuals with Alzheimer’s disease (AD) have increased neurofibrillary tangles (NFTs) of tau proteins but reduced TRIM11, as show

Updated on:April 02,2024 19

New insight into role of amyloid beta in Alzheimer's disease

by Tamara Bhandari,Washington University School of Medicine in St. LouisA new technique for measuring levels in the brain of amyloid beta, a key protein associated with Alzheimer’s disease, woul

Updated on: April 02,2024 16

New insight into role of amyloid beta in Alzheimer's disease

by Tamara Bhandari,Washington University School of Medicine in St. LouisA new technique for measuring levels in the brain of amyloid beta, a key protein associated with Alzheimer’s disease, woul

Updated on:April 02,2024 16