A new treatment reduces inflammation in multiple sclerosis mice models

by Autonomous University of BarcelonaMaR1 reduces pro-inflammatory cytokines in the spinal cord of EAE mice. Plot showing the fold change in cytokine protein levels of different cytokines in the

Updated on: March 25,2024 18

A new treatment reduces inflammation in multiple sclerosis mice models

by Autonomous University of BarcelonaMaR1 reduces pro-inflammatory cytokines in the spinal cord of EAE mice. Plot showing the fold change in cytokine protein levels of different cytokines in the

Updated on:March 25,2024 18

A novel immunotherapy proves effective in animal models of multiple sclerosis

by Thomas Jefferson UniversityThe purified oligodendrocyte extracellular vesicles under an electron microscope. Credit: G. Casella et al., Science Translational Medicine (2020)Multiple sclerosis

Updated on: March 25,2024 14

A novel immunotherapy proves effective in animal models of multiple sclerosis

by Thomas Jefferson UniversityThe purified oligodendrocyte extracellular vesicles under an electron microscope. Credit: G. Casella et al., Science Translational Medicine (2020)Multiple sclerosis

Updated on:March 25,2024 14

Molecular clusters on glial cells show they are more than our brain's 'glue'

FEBRUARY 28, 2024byFred Hutchinson Cancer CenterGraphical abstract. Credit:Cell Reports(2024). DOI: 10.1016/j.celrep.2024.113844Neuroscientists at Fred Hutchinson Cancer Center have

Updated on: March 25,2024 11

Molecular clusters on glial cells show they are more than our brain's 'glue'

FEBRUARY 28, 2024byFred Hutchinson Cancer CenterGraphical abstract. Credit:Cell Reports(2024). DOI: 10.1016/j.celrep.2024.113844Neuroscientists at Fred Hutchinson Cancer Center have

Updated on:March 25,2024 11

Neurobiologists successfully test novel drug principle in a mouse model and in brain organoids of ALS patients

FEBRUARY 8, 2024by Marietta Fuhrmann-Koch,Heidelberg UniversityGraphical abstract. Credit:Cell Reports Medicine(2024). DOI: 10.1016/j.xcrm.2024.101413A research team led by Prof. Dr.

Updated on: March 25,2024 13

Neurobiologists successfully test novel drug principle in a mouse model and in brain organoids of ALS patients

FEBRUARY 8, 2024by Marietta Fuhrmann-Koch,Heidelberg UniversityGraphical abstract. Credit:Cell Reports Medicine(2024). DOI: 10.1016/j.xcrm.2024.101413A research team led by Prof. Dr.

Updated on:March 25,2024 13

Cell engineering team links cancer drug to potential therapy for Alzheimer's disease

FEBRUARY 23, 2024byJohns Hopkins UniversityNeurons that express Lag3 proteins (grey/white) can take in Tau proteins (red) compared with neighboring neurons that do not express Lag3. Credit: Xiao

Updated on: March 25,2024 11

Cell engineering team links cancer drug to potential therapy for Alzheimer's disease

FEBRUARY 23, 2024byJohns Hopkins UniversityNeurons that express Lag3 proteins (grey/white) can take in Tau proteins (red) compared with neighboring neurons that do not express Lag3. Credit: Xiao

Updated on:March 25,2024 11

New drugs cross blood-brain barrier to slow progression and even reverse symptoms of Huntington's disease

FEBRUARY 26, 2024byWeizmann Institute of ScienceCredit:EMBO Molecular Medicine(2024). DOI: 10.1038/s44321-023-00020-yWeizmann Institute scientists have discovered two small molecules

Updated on: March 25,2024 6

New drugs cross blood-brain barrier to slow progression and even reverse symptoms of Huntington's disease

FEBRUARY 26, 2024byWeizmann Institute of ScienceCredit:EMBO Molecular Medicine(2024). DOI: 10.1038/s44321-023-00020-yWeizmann Institute scientists have discovered two small molecules

Updated on:March 25,2024 6

Early-life stress can disrupt maturation of brain's reward circuits, promoting disorders

by University of California, IrvineA projection of CRH/GABA neurons in the medial BLA to the medial NAc shell.a–cRetrograde tracing of CRH+neuronal inputs to medial NAc shell of

Updated on: March 26,2024 14

Early-life stress can disrupt maturation of brain's reward circuits, promoting disorders

by University of California, IrvineA projection of CRH/GABA neurons in the medial BLA to the medial NAc shell.a–cRetrograde tracing of CRH+neuronal inputs to medial NAc shell of

Updated on:March 26,2024 14

A TREM2 activating antibody with a transport vehicle that could boost the metabolism and function of brain microglia

by Ingrid Fadelli , Medical XpressImages showing the architecture of our ATV:TREM2 molecule (a) images showing elevation of microglia proliferation in the brain of mice treated with ATV:TREM2 (b) a su

Updated on: March 26,2024 15

A TREM2 activating antibody with a transport vehicle that could boost the metabolism and function of brain microglia

by Ingrid Fadelli , Medical XpressImages showing the architecture of our ATV:TREM2 molecule (a) images showing elevation of microglia proliferation in the brain of mice treated with ATV:TREM2 (b) a su

Updated on:March 26,2024 15

APOE E2/E2 genotype offers some protection from cognitive decline

by Boston University School of MedicineCredit: Public DomainThe APOE gene—coding for a protein involved in lipid transport and implicated in the clearance of amyloid-beta, one of the proteins tha

Updated on: March 26,2024 13

APOE E2/E2 genotype offers some protection from cognitive decline

by Boston University School of MedicineCredit: Public DomainThe APOE gene—coding for a protein involved in lipid transport and implicated in the clearance of amyloid-beta, one of the proteins tha

Updated on:March 26,2024 13

COVID-19: Advice for caring for people with Alzheimer's disease, mild cognitive impairment

by From Mayo Clinic News NetworkCredit: CC0 Public DomainWith the COVID-19 pandemic at the forefront of daily life, how much information should you share with a loved one who has Alzheimer's disea

Updated on: March 26,2024 14

COVID-19: Advice for caring for people with Alzheimer's disease, mild cognitive impairment

by From Mayo Clinic News NetworkCredit: CC0 Public DomainWith the COVID-19 pandemic at the forefront of daily life, how much information should you share with a loved one who has Alzheimer's disea

Updated on:March 26,2024 14

COVID-19 sees prescriptions increase for dementia drugs linked with serious side-effects

by Alzheimer's Research UKCredit: CC0 Public DomainNew research published inThe Lancetonline finds that not only are dementia deaths up 79% (ONS figures—19th Oct) compared to prev

Updated on: March 26,2024 19

COVID-19 sees prescriptions increase for dementia drugs linked with serious side-effects

by Alzheimer's Research UKCredit: CC0 Public DomainNew research published inThe Lancetonline finds that not only are dementia deaths up 79% (ONS figures—19th Oct) compared to prev

Updated on:March 26,2024 19

Aduhelm: Will Medicare cover the controversial Alzheimer's drug?

by Dennis Thompson(HealthDay)—Following a months-long and unprecedented review, Medicare officials expect to announce within the next couple of weeks whether the program will cover the controversial A

Updated on: March 26,2024 20

Aduhelm: Will Medicare cover the controversial Alzheimer's drug?

by Dennis Thompson(HealthDay)—Following a months-long and unprecedented review, Medicare officials expect to announce within the next couple of weeks whether the program will cover the controversial A

Updated on:March 26,2024 20