Experimental gene therapy for giant axonal neuropathy shows promise in clinical trial

by Erin Bryant,National Institutes of HealthBiopsy of a sensory nerve from a participant in the GAN gene therapy trial (arrows indicate giant axons; regenerating nerve cluster in upper left). So

Updated on: March 27,2024 0

Experimental gene therapy for giant axonal neuropathy shows promise in clinical trial

by Erin Bryant,National Institutes of HealthBiopsy of a sensory nerve from a participant in the GAN gene therapy trial (arrows indicate giant axons; regenerating nerve cluster in upper left). So

Updated on:March 27,2024 0

Consistently exercising 2–3 times a week over the long term linked to lower current insomnia risk

byBritish Medical JournalCredit: Unsplash/CC0 Public DomainConsistently exercising 2–3 times a week over the long term is linked to a lower current risk of insomnia as well as the ability to clo

Updated on: March 27,2024 0

Consistently exercising 2–3 times a week over the long term linked to lower current insomnia risk

byBritish Medical JournalCredit: Unsplash/CC0 Public DomainConsistently exercising 2–3 times a week over the long term is linked to a lower current risk of insomnia as well as the ability to clo

Updated on:March 27,2024 0

New online study explores link between healthy brains and bodies

by Jeff Renaud,University of Western OntarioCredit: Ketut Subiyanto from PexelsSo little is understood about the dialogue between the body and the brain. It might seem obvious that our physical

Updated on: March 27,2024 10

New online study explores link between healthy brains and bodies

by Jeff Renaud,University of Western OntarioCredit: Ketut Subiyanto from PexelsSo little is understood about the dialogue between the body and the brain. It might seem obvious that our physical

Updated on:March 27,2024 10

Scientists identify a key driver of myelin repair

by Nicholas Weiler,Stanford UniversityActin filaments (cyan) and an actin regulatory protein (magenta) in a differentiating oligodendrocyte. Credit: Brad Zuchero and Andrew OlsonNew research fro

Updated on: March 27,2024 0

Scientists identify a key driver of myelin repair

by Nicholas Weiler,Stanford UniversityActin filaments (cyan) and an actin regulatory protein (magenta) in a differentiating oligodendrocyte. Credit: Brad Zuchero and Andrew OlsonNew research fro

Updated on:March 27,2024 0

Developmental crossroads in the brain: How proteins direct nerve cell precursors to turn into specialized neurons

byMax Planck SocietyBrain functions such as motivated behavior, reward learning and decision making are enabled by inhibitory projection neurons. Researchers now show that the protein MEIS2 play

Updated on: March 27,2024 0

Developmental crossroads in the brain: How proteins direct nerve cell precursors to turn into specialized neurons

byMax Planck SocietyBrain functions such as motivated behavior, reward learning and decision making are enabled by inhibitory projection neurons. Researchers now show that the protein MEIS2 play

Updated on:March 27,2024 0

Newly discovered beneficial mutation in mitochondrial DNA seems to help Alzheimer's gene carriers live longer

byUniversity of Southern CaliforniaThe humanin variant P3S is enriched inAPOE4centenarians. (a) Mitochondrial genomic location of the humanin smORF and the P3S mutation. The frequenc

Updated on: March 27,2024 0

Newly discovered beneficial mutation in mitochondrial DNA seems to help Alzheimer's gene carriers live longer

byUniversity of Southern CaliforniaThe humanin variant P3S is enriched inAPOE4centenarians. (a) Mitochondrial genomic location of the humanin smORF and the P3S mutation. The frequenc

Updated on:March 27,2024 0

Study reveals new details about Argonaute syndromes, a class of neurodevelopmental disorders

byUniversity of Massachusetts Medical SchoolVictor Ambros, PhD, and Ye Duan, PhD, show that amino acid changes in the AGO1 protein globally disrupt the RNA silencing process. Credit: University

Updated on: March 27,2024 0

Study reveals new details about Argonaute syndromes, a class of neurodevelopmental disorders

byUniversity of Massachusetts Medical SchoolVictor Ambros, PhD, and Ye Duan, PhD, show that amino acid changes in the AGO1 protein globally disrupt the RNA silencing process. Credit: University

Updated on:March 27,2024 0

First gene therapy for children with metachromatic leukodystrophy approved by FDA

by Lori SolomonThe U.S. Food and Drug Administration has approved Orchard Therapeutics' Lenmeldy (atidarsagene autotemcel) as the first gene therapy for the treatment of children with metachromati

Updated on: March 27,2024 0

First gene therapy for children with metachromatic leukodystrophy approved by FDA

by Lori SolomonThe U.S. Food and Drug Administration has approved Orchard Therapeutics' Lenmeldy (atidarsagene autotemcel) as the first gene therapy for the treatment of children with metachromati

Updated on:March 27,2024 0

Researchers find enzyme plays much larger role in preventing neurodegenerative diseases

JANUARY 31, 2024byIndiana UniversityDeleting NMNAT2 in cortical glutamatergic neurons results in age-dependent axonal degeneration.ABody weight of cKO and their littermate control (c

Updated on: March 28,2024 4

Researchers find enzyme plays much larger role in preventing neurodegenerative diseases

JANUARY 31, 2024byIndiana UniversityDeleting NMNAT2 in cortical glutamatergic neurons results in age-dependent axonal degeneration.ABody weight of cKO and their littermate control (c

Updated on:March 28,2024 4

Researchers make key improvements to Parkinson's disease cell therapies

JULY 13, 2023byMass General BrighamCredit: Pixabay/CC0 Public DomainCell therapy holds promise as a new treatment for Parkinson's disease but, in many trials to date, most transplanted dopam

Updated on: March 28,2024 2

Researchers make key improvements to Parkinson's disease cell therapies

JULY 13, 2023byMass General BrighamCredit: Pixabay/CC0 Public DomainCell therapy holds promise as a new treatment for Parkinson's disease but, in many trials to date, most transplanted dopam

Updated on:March 28,2024 2

Study finds frexalimab has favorable effect on relapsing multiple sclerosis

FEBRUARY 15, 2024by Elana GotkineFor patients with relapsing multiple sclerosis, the anti-CD40L monoclonal antibody frexalimab has a favorable effect on the number of new gadolinium-enhancing T1-weigh

Updated on: March 28,2024 2

Study finds frexalimab has favorable effect on relapsing multiple sclerosis

FEBRUARY 15, 2024by Elana GotkineFor patients with relapsing multiple sclerosis, the anti-CD40L monoclonal antibody frexalimab has a favorable effect on the number of new gadolinium-enhancing T1-weigh

Updated on:March 28,2024 2

Study finds repetitive high concentration capsaicin patch applications beneficial for nerve pain

FEBRUARY 7, 2024byWileyCredit: CC0 Public DomainCapsaicin, derived from hot chili pepper plants, has been used to treat various types of pain, and a high concentration capsaicin patch (HCCP) is

Updated on: March 28,2024 4

Study finds repetitive high concentration capsaicin patch applications beneficial for nerve pain

FEBRUARY 7, 2024byWileyCredit: CC0 Public DomainCapsaicin, derived from hot chili pepper plants, has been used to treat various types of pain, and a high concentration capsaicin patch (HCCP) is

Updated on:March 28,2024 4