Tau does not stabilize microtubules, challenges approach to treating Alzheimer's

by Drexel UniversityThis image represents the role of tau and MAP6 in regulating the stable (green) and dynamic (red) parts of a neuron's microtubules. Depleting tau from cultured rat neurons

Updated on: April 02,2024 16

Tau does not stabilize microtubules, challenges approach to treating Alzheimer's

by Drexel UniversityThis image represents the role of tau and MAP6 in regulating the stable (green) and dynamic (red) parts of a neuron's microtubules. Depleting tau from cultured rat neurons

Updated on:April 02,2024 16

Patients with Alzheimer's disease, dementia face twice the risk of dying after ICU discharge

by American Association of Critical-Care Nurses (AACN)Outcomes after a stay in the intensive care unit for patients in cohorts with versus without Alzheimer disease and related dementia (ADRD). Credit

Updated on: April 02,2024 11

Patients with Alzheimer's disease, dementia face twice the risk of dying after ICU discharge

by American Association of Critical-Care Nurses (AACN)Outcomes after a stay in the intensive care unit for patients in cohorts with versus without Alzheimer disease and related dementia (ADRD). Credit

Updated on:April 02,2024 11

Seeing Alzheimer's disease

by University of MinnesotaCredit: University of MinnesotaWhat if we could diagnose early-stage Alzheimer's disease (AD) by looking into a person's eyes?A retinal scan technique, developed

Updated on: April 02,2024 15

Seeing Alzheimer's disease

by University of MinnesotaCredit: University of MinnesotaWhat if we could diagnose early-stage Alzheimer's disease (AD) by looking into a person's eyes?A retinal scan technique, developed

Updated on:April 02,2024 15

New insight into role of amyloid beta in Alzheimer's disease

by Tamara Bhandari,Washington University School of Medicine in St. LouisA new technique for measuring levels in the brain of amyloid beta, a key protein associated with Alzheimer’s disease, woul

Updated on: April 02,2024 16

New insight into role of amyloid beta in Alzheimer's disease

by Tamara Bhandari,Washington University School of Medicine in St. LouisA new technique for measuring levels in the brain of amyloid beta, a key protein associated with Alzheimer’s disease, woul

Updated on:April 02,2024 16

Tau-regulating protein identified as a promising target for developing Alzheimer's disease treatment

by Perelman School of Medicine at the University of PennsylvaniaIndividuals with Alzheimer’s disease (AD) have increased neurofibrillary tangles (NFTs) of tau proteins but reduced TRIM11, as show

Updated on: April 02,2024 19

Tau-regulating protein identified as a promising target for developing Alzheimer's disease treatment

by Perelman School of Medicine at the University of PennsylvaniaIndividuals with Alzheimer’s disease (AD) have increased neurofibrillary tangles (NFTs) of tau proteins but reduced TRIM11, as show

Updated on:April 02,2024 19

Solanezumab does not slow cognitive decline in preclinical Alzheimer disease

by Elana GotkineFor patients with preclinical Alzheimer disease, solanezumab does not slow cognitive decline, according to a study published online July 17 in theNew England Journal of Medicine&

Updated on: April 02,2024 19

Solanezumab does not slow cognitive decline in preclinical Alzheimer disease

by Elana GotkineFor patients with preclinical Alzheimer disease, solanezumab does not slow cognitive decline, according to a study published online July 17 in theNew England Journal of Medicine&

Updated on:April 02,2024 19

Tau hot spots open new avenues of discovery into dementia

by Queensland Brain InstituteRepresentative diffraction-limited image of a neuroblastoma cell expressing Tau-mEos3.2 molecules acquired in the green channel before single-molecule imaging. Credit: Dr

Updated on: April 02,2024 20

Tau hot spots open new avenues of discovery into dementia

by Queensland Brain InstituteRepresentative diffraction-limited image of a neuroblastoma cell expressing Tau-mEos3.2 molecules acquired in the green channel before single-molecule imaging. Credit: Dr

Updated on:April 02,2024 20

The danger of Z-drugs for dementia patients

by University of East AngliaCredit: CC0 Public DomainStrong sleeping pills known as 'Z-drugs' are linked with an increased risk of falls, fractures and stroke among people with dementia—a

Updated on: April 02,2024 15

The danger of Z-drugs for dementia patients

by University of East AngliaCredit: CC0 Public DomainStrong sleeping pills known as 'Z-drugs' are linked with an increased risk of falls, fractures and stroke among people with dementia—a

Updated on:April 02,2024 15

Alzheimer's: Protective immune cells active decades before symptom onset

by German Center for Neurodegenerative DiseasesCredit: Pixabay/CC0 Public DomainIn individuals with a genetic predisposition to Alzheimer's disease, the immune cells of the brain—the "mi

Updated on: April 02,2024 19

Alzheimer's: Protective immune cells active decades before symptom onset

by German Center for Neurodegenerative DiseasesCredit: Pixabay/CC0 Public DomainIn individuals with a genetic predisposition to Alzheimer's disease, the immune cells of the brain—the "mi

Updated on:April 02,2024 19

Study reveals a driver of brain cell damage in neurodegeneration

by Leah Eisenstadt,Broad Institute of MIT and HarvardA section of brain from a mouse model of neurodegeneration, showing a control protein in green, Nptx2 in red, and glial cells in white. Boost

Updated on: April 02,2024 12

Study reveals a driver of brain cell damage in neurodegeneration

by Leah Eisenstadt,Broad Institute of MIT and HarvardA section of brain from a mouse model of neurodegeneration, showing a control protein in green, Nptx2 in red, and glial cells in white. Boost

Updated on:April 02,2024 12

New information on the pathological mechanisms of Alzheimer's disease

by University of HelsinkiImmunoelectron microscopy image of accumulated tau protein on cell membrane. Credit: Henri HuttunenResearchers at the University of Helsinki have discovered a mechanism b

Updated on: April 02,2024 18

New information on the pathological mechanisms of Alzheimer's disease

by University of HelsinkiImmunoelectron microscopy image of accumulated tau protein on cell membrane. Credit: Henri HuttunenResearchers at the University of Helsinki have discovered a mechanism b

Updated on:April 02,2024 18

Alzheimer's disease: Reduced signals in the brain's forgotten cells

by University of OsloAssociate Professor Rune Enger at the Institute of Basic Medical Sciences at the University of Oslo. Credit: Cecilie Bakken Høstmark, UiOAlzheimer's disease is associated

Updated on: April 02,2024 18

Alzheimer's disease: Reduced signals in the brain's forgotten cells

by University of OsloAssociate Professor Rune Enger at the Institute of Basic Medical Sciences at the University of Oslo. Credit: Cecilie Bakken Høstmark, UiOAlzheimer's disease is associated

Updated on:April 02,2024 18