Alzheimer's risk gene undermines insulation of brain's 'wiring'

by Massachusetts Institute of TechnologyBlack gold staining in postmortem human brain samples from three individuals reveals significantly less myelination in people carrying a copy of the APOE4

Updated on: April 20,2024 18

Alzheimer's risk gene undermines insulation of brain's 'wiring'

by Massachusetts Institute of TechnologyBlack gold staining in postmortem human brain samples from three individuals reveals significantly less myelination in people carrying a copy of the APOE4

Updated on:April 20,2024 18

Is Alzheimer's caused by disruptions to the brain's energy supply?

by Kira Shaw And Orla Bonnar,The ConversationCredit: AI-generated imageIt is well known that Alzheimer's disease, the most common form of dementia, involves the accumulation of sticky protei

Updated on: April 20,2024 0

Is Alzheimer's caused by disruptions to the brain's energy supply?

by Kira Shaw And Orla Bonnar,The ConversationCredit: AI-generated imageIt is well known that Alzheimer's disease, the most common form of dementia, involves the accumulation of sticky protei

Updated on:April 20,2024 0

Diagnosis of Alzheimer's and related dementias reduces social activity

by Rutgers UniversityCredit: Pixabay/CC0 Public DomainDespite the belief that early diagnosis of Alzheimer's disease and other dementias is crucial, a new Rutgers study found that the diagnos

Updated on: April 20,2024 18

Diagnosis of Alzheimer's and related dementias reduces social activity

by Rutgers UniversityCredit: Pixabay/CC0 Public DomainDespite the belief that early diagnosis of Alzheimer's disease and other dementias is crucial, a new Rutgers study found that the diagnos

Updated on:April 20,2024 18

Understanding genetic risk could save sight and predict multiple sclerosis earlier in young people

byUniversity of ExeterCredit: CC0 Public DomainYoung people could be spared from going blind by a new genetic risk tool that could also help diagnose multiple sclerosis (MS) earlier, to start ef

Updated on: April 22,2024 0

Understanding genetic risk could save sight and predict multiple sclerosis earlier in young people

byUniversity of ExeterCredit: CC0 Public DomainYoung people could be spared from going blind by a new genetic risk tool that could also help diagnose multiple sclerosis (MS) earlier, to start ef

Updated on:April 22,2024 0

Scientists identify mutated gene behind mirror movement disorder

byUniversity of MontrealArhgef7 is required for Netrin-1–mediated commissural axon guidance. (A) The mean mRNA expression, fragments per kilobase of transcript per million mapped reads (fpkm), (

Updated on: April 22,2024 0

Scientists identify mutated gene behind mirror movement disorder

byUniversity of MontrealArhgef7 is required for Netrin-1–mediated commissural axon guidance. (A) The mean mRNA expression, fragments per kilobase of transcript per million mapped reads (fpkm), (

Updated on:April 22,2024 0

Caffeine intake interacts with Asian gene variants in Parkinson's disease, may lower risk

bySingHealthComparing ORs for PD stratified by genetic carrier status at LRRK2 risk loci and caffeine consumption. a. Comparing ORs for PD stratified by genetic carrier status at S1647T loci and

Updated on: April 22,2024 0

Caffeine intake interacts with Asian gene variants in Parkinson's disease, may lower risk

bySingHealthComparing ORs for PD stratified by genetic carrier status at LRRK2 risk loci and caffeine consumption. a. Comparing ORs for PD stratified by genetic carrier status at S1647T loci and

Updated on:April 22,2024 0

Scientists identify new 'regulatory' function of learning and memory gene common to all mammalian brain cells

byJohns Hopkins University School of MedicineNeuron showing SynGAP (green) binding to PSD-95 at synapses. Credit: Yoichi Araki and Rick Huganir, Johns Hopkins MedicineJohns Hopkins Medicine neur

Updated on: April 22,2024 0

Scientists identify new 'regulatory' function of learning and memory gene common to all mammalian brain cells

byJohns Hopkins University School of MedicineNeuron showing SynGAP (green) binding to PSD-95 at synapses. Credit: Yoichi Araki and Rick Huganir, Johns Hopkins MedicineJohns Hopkins Medicine neur

Updated on:April 22,2024 0

S1P transporter could be crucial in the development of therapeutics for the treatment of multiple sclerosis

by National University of SingaporeSpns2 deletion affects lymphocyte confinement and the vascular structures of the lymph nodes. A Representative confocal images of T cell zone (CD3-green) and B

Updated on: April 22,2024 13

S1P transporter could be crucial in the development of therapeutics for the treatment of multiple sclerosis

by National University of SingaporeSpns2 deletion affects lymphocyte confinement and the vascular structures of the lymph nodes. A Representative confocal images of T cell zone (CD3-green) and B

Updated on:April 22,2024 13

'New' ALS gene destabilizes neuron's structure and chokes off its nucleus

byNorthwestern UniversityCredit: Pixabay/CC0 Public DomainThe viral ALS Ice Bucket Challenge a few years ago raised major funding that resulted in the discovery of new genes connected to the dis

Updated on: April 23,2024 0

'New' ALS gene destabilizes neuron's structure and chokes off its nucleus

byNorthwestern UniversityCredit: Pixabay/CC0 Public DomainThe viral ALS Ice Bucket Challenge a few years ago raised major funding that resulted in the discovery of new genes connected to the dis

Updated on:April 23,2024 0

Breakthrough in understanding the cause of a rare and life-threatening condition related to sleep apnea

byBen-Gurion University of the NegevGraphical abstract. Credit:The EMBO Journal(2024). DOI: 10.1038/s44318-023-00018-9Ben-Gurion University (BGU) of the Negev's Prof. Gad Vatine

Updated on: April 23,2024 0

Breakthrough in understanding the cause of a rare and life-threatening condition related to sleep apnea

byBen-Gurion University of the NegevGraphical abstract. Credit:The EMBO Journal(2024). DOI: 10.1038/s44318-023-00018-9Ben-Gurion University (BGU) of the Negev's Prof. Gad Vatine

Updated on:April 23,2024 0

Low oxygen levels restore balance and coordination in a mouse model of a movement disorder

by Allessandra DiCorato,Broad Institute of MIT and HarvardCredit: Susanna Hamilton, Broad CommunicationsFriedreich's ataxia is a rare, inherited disease that causes progressive nervous syste

Updated on: April 23,2024 0

Low oxygen levels restore balance and coordination in a mouse model of a movement disorder

by Allessandra DiCorato,Broad Institute of MIT and HarvardCredit: Susanna Hamilton, Broad CommunicationsFriedreich's ataxia is a rare, inherited disease that causes progressive nervous syste

Updated on:April 23,2024 0

Carriers of Alzheimer's genetic marker have greater difficulty harnessing past knowledge

by Baycrest Centre for Geriatric CareDr. Claude Alain, a senior author on the paper and senior scientist at Baycrest's Rotman Research Institute. Credit: Provided by Baycrest.Adults carrying

Updated on: April 23,2024 19

Carriers of Alzheimer's genetic marker have greater difficulty harnessing past knowledge

by Baycrest Centre for Geriatric CareDr. Claude Alain, a senior author on the paper and senior scientist at Baycrest's Rotman Research Institute. Credit: Provided by Baycrest.Adults carrying

Updated on:April 23,2024 19