Scientists uncover new molecular drivers of Alzheimer's

by The Scripps Research InstituteA tiny glass tube (top left) represents the electrode recording from an excitatory human Alzheimer's neuron, generated using modern stem cell techniques (dark

Updated on: June 15,2024 3

Scientists uncover new molecular drivers of Alzheimer's

by The Scripps Research InstituteA tiny glass tube (top left) represents the electrode recording from an excitatory human Alzheimer's neuron, generated using modern stem cell techniques (dark

Updated on:June 15,2024 3

Primary cilia in medulloblastoma: Mechanisms provide treatment opportunity

by St. Jude Children's Research HospitalThe primary cilium is an appendage located on the surface of cells. Here you can see samples of human medulloblastoma representing SHH, WNT, Group 3 an

Updated on: June 15,2024 6

Primary cilia in medulloblastoma: Mechanisms provide treatment opportunity

by St. Jude Children's Research HospitalThe primary cilium is an appendage located on the surface of cells. Here you can see samples of human medulloblastoma representing SHH, WNT, Group 3 an

Updated on:June 15,2024 6

Study uncovers new insights into alternative splicing and disease associations

by Tokyo Medical and Dental UniversityStudy design to create a database of transcripts, called TRAILS (TRAnscriptomic resource of Immune cells using Long-read Sequencing), from different human im

Updated on: June 15,2024 6

Study uncovers new insights into alternative splicing and disease associations

by Tokyo Medical and Dental UniversityStudy design to create a database of transcripts, called TRAILS (TRAnscriptomic resource of Immune cells using Long-read Sequencing), from different human im

Updated on:June 15,2024 6

Multi-omics analysis identifies molecularly defined Alzheimer's disease subtypes

by Jacqueline Mitchell,Beth Israel Deaconess Medical CenterStudy design. Credit:PLOS Biology(2024). DOI: 10.1371/journal.pbio.3002607Omics analysis is the process of analyzing large

Updated on: June 15,2024 7

Multi-omics analysis identifies molecularly defined Alzheimer's disease subtypes

by Jacqueline Mitchell,Beth Israel Deaconess Medical CenterStudy design. Credit:PLOS Biology(2024). DOI: 10.1371/journal.pbio.3002607Omics analysis is the process of analyzing large

Updated on:June 15,2024 7

Possible mechanism for fold formation in the cerebral cortex discovered

by Elena Garrido,Miguel Hernandez University of ElcheImage of a ferret brain showing the altered folding pattern (left) mediated by the Cux2 protein. Credit: IN-CSIC-UMH.Determining the genetic

Updated on: June 15,2024 7

Possible mechanism for fold formation in the cerebral cortex discovered

by Elena Garrido,Miguel Hernandez University of ElcheImage of a ferret brain showing the altered folding pattern (left) mediated by the Cux2 protein. Credit: IN-CSIC-UMH.Determining the genetic

Updated on:June 15,2024 7

Risk factors for Parkinson's disease: Study proves the protective function of the RIT2 gene

by Eurac ResearchIn vivo aSyn overexpression increases endogenous LRRK2 activity, which is prevented by Rit2 co-expression.aPLA analysis of AAV-GFP, AAV-A53T-aSyn and AAV-A53T-aSyn + AAV-R

Updated on: June 17,2024 6

Risk factors for Parkinson's disease: Study proves the protective function of the RIT2 gene

by Eurac ResearchIn vivo aSyn overexpression increases endogenous LRRK2 activity, which is prevented by Rit2 co-expression.aPLA analysis of AAV-GFP, AAV-A53T-aSyn and AAV-A53T-aSyn + AAV-R

Updated on:June 17,2024 6

Can a calculator predict your risk of dementia?

by The Ottawa HospitalResearchers have built and validated an online calculator that empowers individuals 55 and over to better understand the health of their brain and how they can reduce their risk

Updated on: June 18,2024 5

Can a calculator predict your risk of dementia?

by The Ottawa HospitalResearchers have built and validated an online calculator that empowers individuals 55 and over to better understand the health of their brain and how they can reduce their risk

Updated on:June 18,2024 5

Is memory loss mild cognitive impairment, Alzheimer's or just aging? When to get tested

by Eric AdlerCredit: CC0 Public DomainFor people of a certain age, it takes only a few "senior moments"—struggling for words, names or memories—to cause worry.Is this normal aging ormi

Updated on: June 18,2024 4

Is memory loss mild cognitive impairment, Alzheimer's or just aging? When to get tested

by Eric AdlerCredit: CC0 Public DomainFor people of a certain age, it takes only a few "senior moments"—struggling for words, names or memories—to cause worry.Is this normal aging ormi

Updated on:June 18,2024 4

Blood-based multiplexed diagnostic sensor helps to accurately detect Alzheimer's disease

by The Korea Advanced Institute of Science and Technology (KAIST)Figure: A schematic diagram of a high-density aligned carbon nanotube-based resistive sensor that distinguishes patients with Alzh

Updated on: June 18,2024 5

Blood-based multiplexed diagnostic sensor helps to accurately detect Alzheimer's disease

by The Korea Advanced Institute of Science and Technology (KAIST)Figure: A schematic diagram of a high-density aligned carbon nanotube-based resistive sensor that distinguishes patients with Alzh

Updated on:June 18,2024 5

Memory may be preserved in condition with brain changes similar to Alzheimer's disease

by American Academy of NeurologyCredit: Unsplash/CC0 Public DomainPrimary progressive aphasia is a rare neurodegenerative condition characterized by prominent language problems that worsen over t

Updated on: June 18,2024 4

Memory may be preserved in condition with brain changes similar to Alzheimer's disease

by American Academy of NeurologyCredit: Unsplash/CC0 Public DomainPrimary progressive aphasia is a rare neurodegenerative condition characterized by prominent language problems that worsen over t

Updated on:June 18,2024 4

Computational techniques explore 'the dark side of amyloid aggregation in the brain'

by Jianhan Chen,University of Massachusetts AmherstPET scan of a human brain with Alzheimer's disease. Credit: public domainAs physicians and families know too well, though Alzheimer's d

Updated on: June 18,2024 7

Computational techniques explore 'the dark side of amyloid aggregation in the brain'

by Jianhan Chen,University of Massachusetts AmherstPET scan of a human brain with Alzheimer's disease. Credit: public domainAs physicians and families know too well, though Alzheimer's d

Updated on:June 18,2024 7

Emergency/urgent hospitalizations linked to accelerated cognitive decline in older adults

by Rush University Medical CenterCredit: CC0 Public DomainEmergency and urgent hospitalizations are associated with an increased rate of cognitive decline in older adults, report researchers at R

Updated on: June 18,2024 3

Emergency/urgent hospitalizations linked to accelerated cognitive decline in older adults

by Rush University Medical CenterCredit: CC0 Public DomainEmergency and urgent hospitalizations are associated with an increased rate of cognitive decline in older adults, report researchers at R

Updated on:June 18,2024 3