Researchers report on the effectiveness of skin biopsy to detect Parkinson's and related neurodegenerative diseases

byBeth Israel Deaconess Medical CenterCredit: Pixabay/CC0 Public DomainIn a paper published in theJournal of the American Medical Association(JAMA), neurologists at Beth Israel Deaco

Updated on: March 28,2024 0

Researchers report on the effectiveness of skin biopsy to detect Parkinson's and related neurodegenerative diseases

byBeth Israel Deaconess Medical CenterCredit: Pixabay/CC0 Public DomainIn a paper published in theJournal of the American Medical Association(JAMA), neurologists at Beth Israel Deaco

Updated on:March 28,2024 0

Transcriptomic analysis of rat brain response to alternating current electrical stimulation

by Sichuan International Medical Exchange and Promotion AssociationCerebellum of CIVM postnatal rat brain atlas. Credit: NeurolexA new studyappearinginMedCommhas been led by Dr

Updated on: March 28,2024 0

Transcriptomic analysis of rat brain response to alternating current electrical stimulation

by Sichuan International Medical Exchange and Promotion AssociationCerebellum of CIVM postnatal rat brain atlas. Credit: NeurolexA new studyappearinginMedCommhas been led by Dr

Updated on:March 28,2024 0

Novel method facilitates study of oxidized lipids involved in neurodegenerative diseases

NOVEMBER 15, 2023byFAPESPGraphical abstract. Credit:Free Radical Biology and Medicine(2023). DOI: 10.1016/j.freeradbiomed.2023.08.019Lipids are a diversified class of biomolecules wi

Updated on: March 28,2024 4

Novel method facilitates study of oxidized lipids involved in neurodegenerative diseases

NOVEMBER 15, 2023byFAPESPGraphical abstract. Credit:Free Radical Biology and Medicine(2023). DOI: 10.1016/j.freeradbiomed.2023.08.019Lipids are a diversified class of biomolecules wi

Updated on:March 28,2024 4

Promising pathways to simplified Alzheimer's diagnosis unveiled in new study

FEBRUARY 28, 2024by Global Alzheimer's Platform FoundationROC curves for prediction of brain PET or CSF amyloid positivity adjusted for age and apoE ε4 status with imputed values. Credit:Alz

Updated on: March 28,2024 3

Promising pathways to simplified Alzheimer's diagnosis unveiled in new study

FEBRUARY 28, 2024by Global Alzheimer's Platform FoundationROC curves for prediction of brain PET or CSF amyloid positivity adjusted for age and apoE ε4 status with imputed values. Credit:Alz

Updated on:March 28,2024 3

Research overturns previous findings on potential Parkinson's disease target

JANUARY 22, 2024byWalter and Eliza Hall Institute of Medical ResearchDetermining nucleotide-bound PhPINK1 structures. Credit:Science Advances(2024). DOI: 10.1126/sciadv.adj7408A new

Updated on: March 28,2024 3

Research overturns previous findings on potential Parkinson's disease target

JANUARY 22, 2024byWalter and Eliza Hall Institute of Medical ResearchDetermining nucleotide-bound PhPINK1 structures. Credit:Science Advances(2024). DOI: 10.1126/sciadv.adj7408A new

Updated on:March 28,2024 3

Study finds repetitive high concentration capsaicin patch applications beneficial for nerve pain

FEBRUARY 7, 2024byWileyCredit: CC0 Public DomainCapsaicin, derived from hot chili pepper plants, has been used to treat various types of pain, and a high concentration capsaicin patch (HCCP) is

Updated on: March 28,2024 4

Study finds repetitive high concentration capsaicin patch applications beneficial for nerve pain

FEBRUARY 7, 2024byWileyCredit: CC0 Public DomainCapsaicin, derived from hot chili pepper plants, has been used to treat various types of pain, and a high concentration capsaicin patch (HCCP) is

Updated on:March 28,2024 4

Study finds frexalimab has favorable effect on relapsing multiple sclerosis

FEBRUARY 15, 2024by Elana GotkineFor patients with relapsing multiple sclerosis, the anti-CD40L monoclonal antibody frexalimab has a favorable effect on the number of new gadolinium-enhancing T1-weigh

Updated on: March 28,2024 2

Study finds frexalimab has favorable effect on relapsing multiple sclerosis

FEBRUARY 15, 2024by Elana GotkineFor patients with relapsing multiple sclerosis, the anti-CD40L monoclonal antibody frexalimab has a favorable effect on the number of new gadolinium-enhancing T1-weigh

Updated on:March 28,2024 2

Researchers make key improvements to Parkinson's disease cell therapies

JULY 13, 2023byMass General BrighamCredit: Pixabay/CC0 Public DomainCell therapy holds promise as a new treatment for Parkinson's disease but, in many trials to date, most transplanted dopam

Updated on: March 28,2024 2

Researchers make key improvements to Parkinson's disease cell therapies

JULY 13, 2023byMass General BrighamCredit: Pixabay/CC0 Public DomainCell therapy holds promise as a new treatment for Parkinson's disease but, in many trials to date, most transplanted dopam

Updated on:March 28,2024 2

Researchers find enzyme plays much larger role in preventing neurodegenerative diseases

JANUARY 31, 2024byIndiana UniversityDeleting NMNAT2 in cortical glutamatergic neurons results in age-dependent axonal degeneration.ABody weight of cKO and their littermate control (c

Updated on: March 28,2024 4

Researchers find enzyme plays much larger role in preventing neurodegenerative diseases

JANUARY 31, 2024byIndiana UniversityDeleting NMNAT2 in cortical glutamatergic neurons results in age-dependent axonal degeneration.ABody weight of cKO and their littermate control (c

Updated on:March 28,2024 4

First gene therapy for children with metachromatic leukodystrophy approved by FDA

by Lori SolomonThe U.S. Food and Drug Administration has approved Orchard Therapeutics' Lenmeldy (atidarsagene autotemcel) as the first gene therapy for the treatment of children with metachromati

Updated on: March 27,2024 0

First gene therapy for children with metachromatic leukodystrophy approved by FDA

by Lori SolomonThe U.S. Food and Drug Administration has approved Orchard Therapeutics' Lenmeldy (atidarsagene autotemcel) as the first gene therapy for the treatment of children with metachromati

Updated on:March 27,2024 0

Study reveals new details about Argonaute syndromes, a class of neurodevelopmental disorders

byUniversity of Massachusetts Medical SchoolVictor Ambros, PhD, and Ye Duan, PhD, show that amino acid changes in the AGO1 protein globally disrupt the RNA silencing process. Credit: University

Updated on: March 27,2024 0

Study reveals new details about Argonaute syndromes, a class of neurodevelopmental disorders

byUniversity of Massachusetts Medical SchoolVictor Ambros, PhD, and Ye Duan, PhD, show that amino acid changes in the AGO1 protein globally disrupt the RNA silencing process. Credit: University

Updated on:March 27,2024 0

Newly discovered beneficial mutation in mitochondrial DNA seems to help Alzheimer's gene carriers live longer

byUniversity of Southern CaliforniaThe humanin variant P3S is enriched inAPOE4centenarians. (a) Mitochondrial genomic location of the humanin smORF and the P3S mutation. The frequenc

Updated on: March 27,2024 0

Newly discovered beneficial mutation in mitochondrial DNA seems to help Alzheimer's gene carriers live longer

byUniversity of Southern CaliforniaThe humanin variant P3S is enriched inAPOE4centenarians. (a) Mitochondrial genomic location of the humanin smORF and the P3S mutation. The frequenc

Updated on:March 27,2024 0