Protein experts show altered ubiquitin signaling induces hallmarks of sporadic Alzheimer's disease

by Technion - Israel Institute of TechnologyUBB+1accumulates in the early stages of AD postmortem tissue.aImmunofluorescence staining of human tissue (ER = hippocampal complex,

Updated on: March 02,2024 12

Protein experts show altered ubiquitin signaling induces hallmarks of sporadic Alzheimer's disease

by Technion - Israel Institute of TechnologyUBB+1accumulates in the early stages of AD postmortem tissue.aImmunofluorescence staining of human tissue (ER = hippocampal complex,

Updated on:March 02,2024 12

Opinion: New Alzheimer's drugs don't deserve the hype—here's why

by Sebastian Walsh,The ConversationCredit: AI-generated imageA prominent childhood memory is of my grandparents living with and then dying from dementia. As is universal with dementia, there was

Updated on: March 02,2024 20

Opinion: New Alzheimer's drugs don't deserve the hype—here's why

by Sebastian Walsh,The ConversationCredit: AI-generated imageA prominent childhood memory is of my grandparents living with and then dying from dementia. As is universal with dementia, there was

Updated on:March 02,2024 20

Specialized T cells in the brain found to slow progression of Alzheimer's disease

by St. Jude Children's Research HospitalCD8+T cells accumulate in AD and protect mice from AD-associated pathologies.a–c, scRNA-seq analysis of CD45int/+CD11b+(primarily mic

Updated on: March 02,2024 10

Specialized T cells in the brain found to slow progression of Alzheimer's disease

by St. Jude Children's Research HospitalCD8+T cells accumulate in AD and protect mice from AD-associated pathologies.a–c, scRNA-seq analysis of CD45int/+CD11b+(primarily mic

Updated on:March 02,2024 10

'Anti-tangle' molecule could aid search for new dementia treatments, say scientists

by Vicky Just,University of BathThe solution NMR structure of αS1–25(A) The average structure of αS1–25derived from the 20 lowest-energy structures. Charged (blue: positive, red: negative)

Updated on: March 02,2024 20

'Anti-tangle' molecule could aid search for new dementia treatments, say scientists

by Vicky Just,University of BathThe solution NMR structure of αS1–25(A) The average structure of αS1–25derived from the 20 lowest-energy structures. Charged (blue: positive, red: negative)

Updated on:March 02,2024 20

Care home study highlights poor care for dementia residents with hearing problems

by Mike Addelman,University of ManchesterCredit: Unsplash/CC0 Public DomainHard of hearing people with dementia are not receiving the care they desperately need, according to a new study by Univ

Updated on: March 02,2024 11

Care home study highlights poor care for dementia residents with hearing problems

by Mike Addelman,University of ManchesterCredit: Unsplash/CC0 Public DomainHard of hearing people with dementia are not receiving the care they desperately need, according to a new study by Univ

Updated on:March 02,2024 11

New Alzheimer's disease pathways identified

by University of LübeckPath model of main findings. This path model summarizes the main-effect mediation model. Circles indicate principal components or latent variables, rectangles represent observed

Updated on: March 02,2024 11

New Alzheimer's disease pathways identified

by University of LübeckPath model of main findings. This path model summarizes the main-effect mediation model. Circles indicate principal components or latent variables, rectangles represent observed

Updated on:March 02,2024 11

Examining dementia risk in adults with intellectual disability

by Okayama UniversityLittle is known about the risk factors of dementia in people diagnosed with intellectual disabilities. Researchers at Okayama University Hospital, Okayama University, and Asa

Updated on: March 02,2024 19

Examining dementia risk in adults with intellectual disability

by Okayama UniversityLittle is known about the risk factors of dementia in people diagnosed with intellectual disabilities. Researchers at Okayama University Hospital, Okayama University, and Asa

Updated on:March 02,2024 19

Public health initiatives can support caregivers of people with Alzheimer's and related dementia

by University of MinnesotaConceptual model: Intersection of social determinants of health and dementia caregiving. Credit:Alzheimer's & Dementia(2023). DOI: 10.1002/alz.13437U

Updated on: March 02,2024 19

Public health initiatives can support caregivers of people with Alzheimer's and related dementia

by University of MinnesotaConceptual model: Intersection of social determinants of health and dementia caregiving. Credit:Alzheimer's & Dementia(2023). DOI: 10.1002/alz.13437U

Updated on:March 02,2024 19

Telecare found to cut costs, boost quality of life for dementia patients

by University of California, San FranciscoCredit: CC0 Public DomainA UCSF telecare program that improves outcomes for patients with dementia and lightens the load for unpaid caregivers also has t

Updated on: March 02,2024 18

Telecare found to cut costs, boost quality of life for dementia patients

by University of California, San FranciscoCredit: CC0 Public DomainA UCSF telecare program that improves outcomes for patients with dementia and lightens the load for unpaid caregivers also has t

Updated on:March 02,2024 18

Study reports on contributions to white matter injury in Alzheimer's disease

by Impact Journals LLCA vicious cycle generating WM injury driven by mixed vascular and ADNC in the aging human white matter. Diagnostic challenges for IHC and neuroimaging. Credit:Aging(2

Updated on: March 02,2024 19

Study reports on contributions to white matter injury in Alzheimer's disease

by Impact Journals LLCA vicious cycle generating WM injury driven by mixed vascular and ADNC in the aging human white matter. Diagnostic challenges for IHC and neuroimaging. Credit:Aging(2

Updated on:March 02,2024 19

Panel of 48 CSF proteins complements existing Alzheimer biomarkers

by Elana GotkineA panel of 48 proteins in the cerebrospinal fluid (CSF 48 panel) complements existing CSF biomarkers for Alzheimer disease (AD), according to a study published in the Sept. 6 issue of&

Updated on: March 02,2024 15

Panel of 48 CSF proteins complements existing Alzheimer biomarkers

by Elana GotkineA panel of 48 proteins in the cerebrospinal fluid (CSF 48 panel) complements existing CSF biomarkers for Alzheimer disease (AD), according to a study published in the Sept. 6 issue of&

Updated on:March 02,2024 15

New perspectives on understanding, preventing and treating vascular dementia

by Hôpitaux Universitaires de GenèveCCR5 expression in response to oxidative stress is mediated by NF-κB. (A)Upper: Schematic overview of the murineCcr5gene. Blue boxes represent int

Updated on: March 02,2024 12

New perspectives on understanding, preventing and treating vascular dementia

by Hôpitaux Universitaires de GenèveCCR5 expression in response to oxidative stress is mediated by NF-κB. (A)Upper: Schematic overview of the murineCcr5gene. Blue boxes represent int

Updated on:March 02,2024 12