A therapeutic target for Alzheimer's disease discovered

by Laval UniversityFRET ratio is independent of laser intensity, and imaging depth was comparable between NonTg and 5xFAD mice. (A) Confocal image of the AAV2/9.CaMKIIa.SuperClomeleon (SCLM) infe

Updated on: May 28,2024 8

A therapeutic target for Alzheimer's disease discovered

by Laval UniversityFRET ratio is independent of laser intensity, and imaging depth was comparable between NonTg and 5xFAD mice. (A) Confocal image of the AAV2/9.CaMKIIa.SuperClomeleon (SCLM) infe

Updated on:May 28,2024 8

Are stressed-out brain cells the root cause of neurodegenerative disease?

byUniversity of California - BerkeleyAn illustration of a brain cell in a person with Alzheimer's disease, showing the accumulation and clumping of tau proteins (blue squiggles) in the cytop

Updated on: April 09,2024 0

Are stressed-out brain cells the root cause of neurodegenerative disease?

byUniversity of California - BerkeleyAn illustration of a brain cell in a person with Alzheimer's disease, showing the accumulation and clumping of tau proteins (blue squiggles) in the cytop

Updated on:April 09,2024 0

60 years later, high school quality may have a long-term impact on cognition

by Columbia University Irving Medical CenterCredit: Unsplash/CC0 Public DomainA study of more than 2,200 adults who attended U.S. high schools in the early 1960s found that those who attended hig

Updated on: March 24,2024 16

60 years later, high school quality may have a long-term impact on cognition

by Columbia University Irving Medical CenterCredit: Unsplash/CC0 Public DomainA study of more than 2,200 adults who attended U.S. high schools in the early 1960s found that those who attended hig

Updated on:March 24,2024 16

What happens around an Alzheimer plaque?

by VIB (the Flanders Institute for Biotechnology)PET scan of a human brain with Alzheimer's disease. Credit: public domainThe brains of people living with Alzheimer's are riddled with pla

Updated on: April 02,2024 10

What happens around an Alzheimer plaque?

by VIB (the Flanders Institute for Biotechnology)PET scan of a human brain with Alzheimer's disease. Credit: public domainThe brains of people living with Alzheimer's are riddled with pla

Updated on:April 02,2024 10

Silencing a faulty gene may uncover clues to rare forms of ALS

by National Institutes of HealthCredit: Pixabay/CC0 Public DomainUsing an experimental drug, researchers have been able to suppress a mutated amyotrophic lateral sclerosis (ALS) gene. Studies in

Updated on: February 05,2024 15

Silencing a faulty gene may uncover clues to rare forms of ALS

by National Institutes of HealthCredit: Pixabay/CC0 Public DomainUsing an experimental drug, researchers have been able to suppress a mutated amyotrophic lateral sclerosis (ALS) gene. Studies in

Updated on:February 05,2024 15

Dial for tuning dopamine, environmental signals found in Parkinson's

by University of Alabama in TuscaloosaC. elegans, seen here as hundreds living on a plate viewed through the lens of a microscope, share roughly half their genes with humans. Credit: The Universi

Updated on: February 05,2024 20

Dial for tuning dopamine, environmental signals found in Parkinson's

by University of Alabama in TuscaloosaC. elegans, seen here as hundreds living on a plate viewed through the lens of a microscope, share roughly half their genes with humans. Credit: The Universi

Updated on:February 05,2024 20

Interfering with antiviral pathway may deter Alzheimer's disease and frontotemporal dementia

by Weill Cornell Medical CollegeThe cGAS–STING pathway is activated in the hippocampi of mice with tauopathy and in human AD brains. Credit:Nature Neuroscience(2023). DOI: 10.1038/s41

Updated on: June 04,2024 3

Interfering with antiviral pathway may deter Alzheimer's disease and frontotemporal dementia

by Weill Cornell Medical CollegeThe cGAS–STING pathway is activated in the hippocampi of mice with tauopathy and in human AD brains. Credit:Nature Neuroscience(2023). DOI: 10.1038/s41

Updated on:June 04,2024 3

Cognitive function maintained among elderly who feel good about life

by University of MichiganCredit: Pixabay/CC0 Public DomainFeeling happy about life slowed the cognitive decline among older adults in China, a new 12-year study suggests.Researchers found that th

Updated on: May 26,2024 6

Cognitive function maintained among elderly who feel good about life

by University of MichiganCredit: Pixabay/CC0 Public DomainFeeling happy about life slowed the cognitive decline among older adults in China, a new 12-year study suggests.Researchers found that th

Updated on:May 26,2024 6

Piecing the puzzle together: How different brain regions contribute to visual object memory

by The National Institutes for Quantum Science and TechnologyDiagram of the ventral fronto-temporal network operations necessary for visual object memory. During perception (left), neurons in the ante

Updated on: September 06,2024 0

Piecing the puzzle together: How different brain regions contribute to visual object memory

by The National Institutes for Quantum Science and TechnologyDiagram of the ventral fronto-temporal network operations necessary for visual object memory. During perception (left), neurons in the ante

Updated on:September 06,2024 0

Modified protein can prevent Alzheimer's disease in mice

by Shi En Kim,University of ChicagoNeurons in the brain of a mouse with Alzheimer's disease. New research from UChicago shows how a modified piece of one protein can prevent the disease in m

Updated on: June 04,2024 5

Modified protein can prevent Alzheimer's disease in mice

by Shi En Kim,University of ChicagoNeurons in the brain of a mouse with Alzheimer's disease. New research from UChicago shows how a modified piece of one protein can prevent the disease in m

Updated on:June 04,2024 5

Florida researchers are giving depressed, anxious people psychedelics

by Caroline Catherman, Orlando SentinelCredit: Unsplash/CC0 Public DomainA therapy session with Patricia Brown starts like any other. She leads her clients into a peaceful, quiet room, draped in beige

Updated on: January 11,2024 9

Florida researchers are giving depressed, anxious people psychedelics

by Caroline Catherman, Orlando SentinelCredit: Unsplash/CC0 Public DomainA therapy session with Patricia Brown starts like any other. She leads her clients into a peaceful, quiet room, draped in beige

Updated on:January 11,2024 9

A TREM2 activating antibody with a transport vehicle that could boost the metabolism and function of brain microglia

by Ingrid Fadelli , Medical XpressImages showing the architecture of our ATV:TREM2 molecule (a) images showing elevation of microglia proliferation in the brain of mice treated with ATV:TREM2 (b) a su

Updated on: March 26,2024 15

A TREM2 activating antibody with a transport vehicle that could boost the metabolism and function of brain microglia

by Ingrid Fadelli , Medical XpressImages showing the architecture of our ATV:TREM2 molecule (a) images showing elevation of microglia proliferation in the brain of mice treated with ATV:TREM2 (b) a su

Updated on:March 26,2024 15