Degrading modified proteins could treat Alzheimer's, other 'undruggable' diseases

by American Chemical SocietyGraphical abstract. Credit:ACS Central Science(2023). DOI: 10.1021/acscentsci.2c01369Certain diseases, including Alzheimer's, are currently considered

Updated on: June 24,2024 7

Degrading modified proteins could treat Alzheimer's, other 'undruggable' diseases

by American Chemical SocietyGraphical abstract. Credit:ACS Central Science(2023). DOI: 10.1021/acscentsci.2c01369Certain diseases, including Alzheimer's, are currently considered

Updated on:June 24,2024 7

How dementia quality registries can contribute to better dementia care

by Austrian Institute for Health Technology Assessment GmbHCredit: Pixabay/CC0 Public DomainThe Austrian Institute for Health Technology Assessment (AIHTA) has investigated which key factors are essen

Updated on: May 11,2024 3

How dementia quality registries can contribute to better dementia care

by Austrian Institute for Health Technology Assessment GmbHCredit: Pixabay/CC0 Public DomainThe Austrian Institute for Health Technology Assessment (AIHTA) has investigated which key factors are essen

Updated on:May 11,2024 3

Pioneering surgical approach set to pave the way for hearing loss treatment

byUniversity of SheffieldDrawing showing the trajectory for injection to the cochlear nerve in the internal auditory meatus via the round window. Image by Karin Lodin. Credit:Scientific Re

Updated on: November 27,2024 0

Pioneering surgical approach set to pave the way for hearing loss treatment

byUniversity of SheffieldDrawing showing the trajectory for injection to the cochlear nerve in the internal auditory meatus via the round window. Image by Karin Lodin. Credit:Scientific Re

Updated on:November 27,2024 0

Study finds no uniform brain shrinkage pattern in Alzheimer's

byUniversity College LondonMapped is the proportion of participants with a high rate of atrophy in cortical (left) and subcortical (right) areas. AD, Alzheimer's disease; MCI, mild cognitive

Updated on: October 16,2024 0

Study finds no uniform brain shrinkage pattern in Alzheimer's

byUniversity College LondonMapped is the proportion of participants with a high rate of atrophy in cortical (left) and subcortical (right) areas. AD, Alzheimer's disease; MCI, mild cognitive

Updated on:October 16,2024 0

Identification of a central regulator

by Ludwig Maximilian University of MunichC1q (green) and ApoE (red) proteins form deposits in the choroid plexus, as the researchers revealed by super-resolution microscopy. Bar 1 µm. Credit: C.

Updated on: March 09,2024 15

Identification of a central regulator

by Ludwig Maximilian University of MunichC1q (green) and ApoE (red) proteins form deposits in the choroid plexus, as the researchers revealed by super-resolution microscopy. Bar 1 µm. Credit: C.

Updated on:March 09,2024 15

Early abnormalities of Alzheimer's disease: It takes two (proteins) to tango

by McGill UniversityCredit: McGill UniversityFor years, neuroscientists have puzzled over how two abnormal proteins, called amyloid and tau, accumulate in the brain and damage it to cause Alzheim

Updated on: February 28,2024 19

Early abnormalities of Alzheimer's disease: It takes two (proteins) to tango

by McGill UniversityCredit: McGill UniversityFor years, neuroscientists have puzzled over how two abnormal proteins, called amyloid and tau, accumulate in the brain and damage it to cause Alzheim

Updated on:February 28,2024 19

New therapy may rapidly reverse life-changing sepsis-induced brain injury, animal study suggests

by Florey Institute of Neuroscience and Mental HealthCredit: Florey Institute of Neuroscience and Mental HealthFlorey researchers have shown that an extremely large "megadose" of sodium asco

Updated on: July 05,2024 0

New therapy may rapidly reverse life-changing sepsis-induced brain injury, animal study suggests

by Florey Institute of Neuroscience and Mental HealthCredit: Florey Institute of Neuroscience and Mental HealthFlorey researchers have shown that an extremely large "megadose" of sodium asco

Updated on:July 05,2024 0

Alzheimer's disease may cause vicious circle between brain network and immune cell dysfunctions

by Sarah C.p. Williams,Gladstone InstitutesA new study by Gladstone scientists suggests that certain anti-epileptic or tau-reducing treatments could be promising for people in the early stages o

Updated on: April 10,2024 20

Alzheimer's disease may cause vicious circle between brain network and immune cell dysfunctions

by Sarah C.p. Williams,Gladstone InstitutesA new study by Gladstone scientists suggests that certain anti-epileptic or tau-reducing treatments could be promising for people in the early stages o

Updated on:April 10,2024 20

Genetic technique reverses Alzheimer's processes in mice

by Alzheimer's Research UKResearchers in the US have used genetic techniques to slow the progression of Alzheimer's in mice that show features of the disease. The study, which centered ar

Updated on: March 07,2024 20

Genetic technique reverses Alzheimer's processes in mice

by Alzheimer's Research UKResearchers in the US have used genetic techniques to slow the progression of Alzheimer's in mice that show features of the disease. The study, which centered ar

Updated on:March 07,2024 20

Llama nanobodies: New therapy can neutralize a wide variety of HIV-1 strains

by Noelle Toumey Reetz,Georgia State UniversityCryo-EM structures of nanobodies R27 and G36 in complex with HIV-1 Env trimer reveal modes of recognition similar to J3. Credit:Advanced Scie

Updated on: August 01,2024 0

Llama nanobodies: New therapy can neutralize a wide variety of HIV-1 strains

by Noelle Toumey Reetz,Georgia State UniversityCryo-EM structures of nanobodies R27 and G36 in complex with HIV-1 Env trimer reveal modes of recognition similar to J3. Credit:Advanced Scie

Updated on:August 01,2024 0

Brain blood flow resistance more common in older adults with cognitive problems

byAmerican Physiological SocietyComparisons of cerebrovascular impedance coherence (top) and modulus (Z, bottom) between cognitive normal subjects (CN) and patients with amnestic mild cognitive

Updated on: November 05,2024 0

Brain blood flow resistance more common in older adults with cognitive problems

byAmerican Physiological SocietyComparisons of cerebrovascular impedance coherence (top) and modulus (Z, bottom) between cognitive normal subjects (CN) and patients with amnestic mild cognitive

Updated on:November 05,2024 0

Minimally invasive neural interface allows brain access without skull opening

byRice UniversityEndocisternal neural interface in human and sheep models. Credit:Nature Biomedical Engineering(2024). DOI: 10.1038/s41551-024-01281-9A team of researchers led by Ric

Updated on: November 28,2024 0

Minimally invasive neural interface allows brain access without skull opening

byRice UniversityEndocisternal neural interface in human and sheep models. Credit:Nature Biomedical Engineering(2024). DOI: 10.1038/s41551-024-01281-9A team of researchers led by Ric

Updated on:November 28,2024 0