Study finds tumor growth fueled by nucleotide salvage

byUTSouthwestern Medical CenterGraphical abstract. Credit:Cell(2024). DOI: 10.1016/j.cell.2024.05.011Cancer cells salvage purine nucleotides to fuel tumor growth, including pur

Updated on: August 01,2024

Study finds tumor growth fueled by nucleotide salvage

byUTSouthwestern Medical CenterGraphical abstract. Credit:Cell(2024). DOI: 10.1016/j.cell.2024.05.011Cancer cells salvage purine nucleotides to fuel tumor growth, including pur

Updated on:August 01,2024

Cardiometabolic diseases may influence both risk and progression of motor neuron diseases

Cardiometabolic diseases may influence both risk and progression of motor neuron diseasesbyKarolinska InstitutetCredit: PixabayA new study from the Institute of Environmental Medicine (IMM),&nbs

Updated on: January 15,2025

Cardiometabolic diseases may influence both risk and progression of motor neuron diseases

Cardiometabolic diseases may influence both risk and progression of motor neuron diseasesbyKarolinska InstitutetCredit: PixabayA new study from the Institute of Environmental Medicine (IMM),&nbs

Updated on:January 15,2025

Combining cell therapy with approved drug shows promise for treating multiple sclerosis

byJosep Carreras Leukaemia Research InstituteCredit: Pixabay/CC0 Public DomainMultiple sclerosis (MS) is a long-term disease where the immune system mistakenly attacks the protective layer aroun

Updated on: October 14,2024

Combining cell therapy with approved drug shows promise for treating multiple sclerosis

byJosep Carreras Leukaemia Research InstituteCredit: Pixabay/CC0 Public DomainMultiple sclerosis (MS) is a long-term disease where the immune system mistakenly attacks the protective layer aroun

Updated on:October 14,2024

Researchers identify 'neurostatin' that may reduce the risk of Alzheimer's disease

by University of CambridgeDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.Researchers have identified a drug that targets the first step in the toxi

Updated on: February 28,2024

Researchers identify 'neurostatin' that may reduce the risk of Alzheimer's disease

by University of CambridgeDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.Researchers have identified a drug that targets the first step in the toxi

Updated on:February 28,2024

Brain's 'speedometer' could help solve part of dementia puzzle

by University of ExeterCredit: Unsplash/CC0 Public DomainNearly one million people in the UK have dementia. People living with the most common form, Alzheimer's disease, can experience diffic

Updated on: May 18,2024

Brain's 'speedometer' could help solve part of dementia puzzle

by University of ExeterCredit: Unsplash/CC0 Public DomainNearly one million people in the UK have dementia. People living with the most common form, Alzheimer's disease, can experience diffic

Updated on:May 18,2024

Understanding the genetic roots of rare mutations in Alzheimer's disease

byVIB (the Flanders Institute for Biotechnology)Hippocampal neurons with staining for endosomes (turquoise and purple) and lysosomes (yellow). When the PSEN2 gene is absent or carries a familial

Updated on: December 11,2024

Understanding the genetic roots of rare mutations in Alzheimer's disease

byVIB (the Flanders Institute for Biotechnology)Hippocampal neurons with staining for endosomes (turquoise and purple) and lysosomes (yellow). When the PSEN2 gene is absent or carries a familial

Updated on:December 11,2024

Old drug offers new hope to treat Alzheimer's disease

by Gladstone InstitutesVarious pills. Credit: WikipediaScientists from the Gladstone Institutes have discovered that salsalate, a drug used to treat rheumatoid arthritis, effectively reversed tau

Updated on: February 26,2024

Old drug offers new hope to treat Alzheimer's disease

by Gladstone InstitutesVarious pills. Credit: WikipediaScientists from the Gladstone Institutes have discovered that salsalate, a drug used to treat rheumatoid arthritis, effectively reversed tau

Updated on:February 26,2024

A toxic byproduct of hemoglobin could provide treatments for Creutzfeldt-Jakob Disease

by Case Western Reserve UniversityScientists at Case Western Reserve University School of Medicine have identified a novel mechanism that could be used to protect the brain from damage due to str

Updated on: February 28,2024

A toxic byproduct of hemoglobin could provide treatments for Creutzfeldt-Jakob Disease

by Case Western Reserve UniversityScientists at Case Western Reserve University School of Medicine have identified a novel mechanism that could be used to protect the brain from damage due to str

Updated on:February 28,2024

Faults in the blood-brain barrier implicated in dementia

by Alzheimer's Research UKCalifornia based researchers have found that damage to cells known as pericytes, which surround small blood vessels in the brain, may trigger a chain of events that

Updated on: March 07,2024

Faults in the blood-brain barrier implicated in dementia

by Alzheimer's Research UKCalifornia based researchers have found that damage to cells known as pericytes, which surround small blood vessels in the brain, may trigger a chain of events that

Updated on:March 07,2024

New review suggests evaluating Tibetan medicinal herb as potential treatment for mild cognitive impairment

by Stephanie Baum , Medical XpressCredit:Frontiers in Pharmacology(2024). DOI: 10.3389/fphar.2024.1484040Within Tibetan medicine, the medicinal herb Terminalia chebula (T. chebula) is well

Updated on: November 07,2024

New review suggests evaluating Tibetan medicinal herb as potential treatment for mild cognitive impairment

by Stephanie Baum , Medical XpressCredit:Frontiers in Pharmacology(2024). DOI: 10.3389/fphar.2024.1484040Within Tibetan medicine, the medicinal herb Terminalia chebula (T. chebula) is well

Updated on:November 07,2024

Driving behaviors harbor early signals of dementia

by Columbia University's Mailman School of Public HealthCredit: CC0 Public DomainUsing naturalistic driving data and machine learning techniques, researchers at Columbia University Mailman Sc

Updated on: June 20,2024

Driving behaviors harbor early signals of dementia

by Columbia University's Mailman School of Public HealthCredit: CC0 Public DomainUsing naturalistic driving data and machine learning techniques, researchers at Columbia University Mailman Sc

Updated on:June 20,2024

P-glycoprotein removes Alzheimer's-associated toxin from the brain

by Southern Methodist University(A) The first frame of SMU's simulation shows amyloid-β bound to the drug binding domains of P-gp. (B) The final frame of the same simulation shows P-gp pushin

Updated on: April 01,2024

P-glycoprotein removes Alzheimer's-associated toxin from the brain

by Southern Methodist University(A) The first frame of SMU's simulation shows amyloid-β bound to the drug binding domains of P-gp. (B) The final frame of the same simulation shows P-gp pushin

Updated on:April 01,2024