Alzheimer's disease: How amyloid aggregates alter neuronal function

by CNRSRat hippocampal neurons in primary culture, showing a fluorescent soluble protein (left) and trajectories corresponding to the movement of the glutamate receptors on its surface, measured

Updated on: April 08,2024

Alzheimer's disease: How amyloid aggregates alter neuronal function

by CNRSRat hippocampal neurons in primary culture, showing a fluorescent soluble protein (left) and trajectories corresponding to the movement of the glutamate receptors on its surface, measured

Updated on:April 08,2024

Image: Neurologist creates image of Alzheimer's plaque in neurons

by Bill Hathaway,Yale UniversityThe effects of the plaques on the brains of Alzheimer's patients are devastating.But when postdoctoral associate Peng Yuan and Dr. Jaime Grutzendler, associat

Updated on: February 28,2024

Image: Neurologist creates image of Alzheimer's plaque in neurons

by Bill Hathaway,Yale UniversityThe effects of the plaques on the brains of Alzheimer's patients are devastating.But when postdoctoral associate Peng Yuan and Dr. Jaime Grutzendler, associat

Updated on:February 28,2024

Degrading modified proteins could treat Alzheimer's, other 'undruggable' diseases

by American Chemical SocietyGraphical abstract. Credit:ACS Central Science(2023). DOI: 10.1021/acscentsci.2c01369Certain diseases, including Alzheimer's, are currently considered

Updated on: June 24,2024

Degrading modified proteins could treat Alzheimer's, other 'undruggable' diseases

by American Chemical SocietyGraphical abstract. Credit:ACS Central Science(2023). DOI: 10.1021/acscentsci.2c01369Certain diseases, including Alzheimer's, are currently considered

Updated on:June 24,2024

FAU site for first US clinical trial for Lewy Body dementia

by Florida Atlantic UniversityThe South Florida clinical trial is directed by one of the world's leading neuroscientists and an expert on LBD, James E. Galvin, M.D., M.P.H., a professor of cl

Updated on: February 28,2024

FAU site for first US clinical trial for Lewy Body dementia

by Florida Atlantic UniversityThe South Florida clinical trial is directed by one of the world's leading neuroscientists and an expert on LBD, James E. Galvin, M.D., M.P.H., a professor of cl

Updated on:February 28,2024

Advanced infant brain development may not always be a good thing

by Mallory Locklear,Yale UniversityOverview of study design. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-54657-5The human brain undergoes significant development duri

Updated on: December 16,2024

Advanced infant brain development may not always be a good thing

by Mallory Locklear,Yale UniversityOverview of study design. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-54657-5The human brain undergoes significant development duri

Updated on:December 16,2024

Tdap vaccination tied to lower dementia risk in older adults

Tetanus, diphtheria, pertussis (Tdap) vaccination in older adults is associated with a 42 percent lower dementia risk, according to a study recently published inTheJournals of Gerontology,

Updated on: July 01,2024

Tdap vaccination tied to lower dementia risk in older adults

Tetanus, diphtheria, pertussis (Tdap) vaccination in older adults is associated with a 42 percent lower dementia risk, according to a study recently published inTheJournals of Gerontology,

Updated on:July 01,2024

P-glycoprotein removes Alzheimer's-associated toxin from the brain

by Southern Methodist University(A) The first frame of SMU's simulation shows amyloid-β bound to the drug binding domains of P-gp. (B) The final frame of the same simulation shows P-gp pushin

Updated on: April 01,2024

P-glycoprotein removes Alzheimer's-associated toxin from the brain

by Southern Methodist University(A) The first frame of SMU's simulation shows amyloid-β bound to the drug binding domains of P-gp. (B) The final frame of the same simulation shows P-gp pushin

Updated on:April 01,2024

Among the oldest adults, poor balance may signal higher risk for dementia

by American Geriatrics SocietyThis research summary was developed as a public education tool by the Health in Aging Foundation. The Foundation is a national non-profit established in 1999 by the Ameri

Updated on: March 09,2024

Among the oldest adults, poor balance may signal higher risk for dementia

by American Geriatrics SocietyThis research summary was developed as a public education tool by the Health in Aging Foundation. The Foundation is a national non-profit established in 1999 by the Ameri

Updated on:March 09,2024

Drug discovery paradigm targets Tau protein aggregation linked to the Alzheimer's disease

by Bentham Science PublishersDementia and other tauopathies, most notably Alzheimer's disease, embody a class of neurodegenerative diseases associated with the aggregation of the Tau protein in th

Updated on: February 28,2024

Drug discovery paradigm targets Tau protein aggregation linked to the Alzheimer's disease

by Bentham Science PublishersDementia and other tauopathies, most notably Alzheimer's disease, embody a class of neurodegenerative diseases associated with the aggregation of the Tau protein in th

Updated on:February 28,2024

Body's immune system may play larger role in Alzheimer's disease than thought

by University of California, IrvineMicroglia (green) surround an amyloid plaque (blue) in the brain of an Alzheimer's disease mouse model. UCI researchers have shown that endogenous mouse ant

Updated on: February 28,2024

Body's immune system may play larger role in Alzheimer's disease than thought

by University of California, IrvineMicroglia (green) surround an amyloid plaque (blue) in the brain of an Alzheimer's disease mouse model. UCI researchers have shown that endogenous mouse ant

Updated on:February 28,2024

Facial expressions of pain can be predicted from brain activity, researchers show

by Béatrice St-Cyr-Leroux,University of MontrealSpatial similarity between the FEPS and other pain-related signatures. Credit:(2024). DOI: 10.7554/eLife.87962.2Stubbing your toe on a table

Updated on: December 17,2024

Facial expressions of pain can be predicted from brain activity, researchers show

by Béatrice St-Cyr-Leroux,University of MontrealSpatial similarity between the FEPS and other pain-related signatures. Credit:(2024). DOI: 10.7554/eLife.87962.2Stubbing your toe on a table

Updated on:December 17,2024

Review finds no benefit to aspirin for preserving cognitive function

by WileyCoated aspirin tablets. Image: Wikimedia Commons.An analysis of published studies found no evidence that low- dose aspirin buffers against cognitive decline or dementia or improves cognit

Updated on: March 09,2024

Review finds no benefit to aspirin for preserving cognitive function

by WileyCoated aspirin tablets. Image: Wikimedia Commons.An analysis of published studies found no evidence that low- dose aspirin buffers against cognitive decline or dementia or improves cognit

Updated on:March 09,2024