Alzheimer's: New study supports amyloid hypothesis but suggests alternative treatment

by Columbia UniversityCREB3L2-ATF4 up-regulation in β-amyloid pathology 5xFAD model. In vivo detection and quantification of CREB3L2-ATF4 dimers by PLA in the dentate gyrus of 10-week-old 5xFAD o

Updated on: April 10,2024

Alzheimer's: New study supports amyloid hypothesis but suggests alternative treatment

by Columbia UniversityCREB3L2-ATF4 up-regulation in β-amyloid pathology 5xFAD model. In vivo detection and quantification of CREB3L2-ATF4 dimers by PLA in the dentate gyrus of 10-week-old 5xFAD o

Updated on:April 10,2024

How Alzheimer's disease spreads throughout the brain – new study

by Thomas E Cope,The ConversationHarmful tau protein spreads through networks.Alzheimer's disease is a devastating brain illness that affects anestimated 47m peopleworldwide. It

Updated on: April 10,2024

How Alzheimer's disease spreads throughout the brain – new study

by Thomas E Cope,The ConversationHarmful tau protein spreads through networks.Alzheimer's disease is a devastating brain illness that affects anestimated 47m peopleworldwide. It

Updated on:April 10,2024

Nearly a third of Americans use gray market caregivers to aid the elderly and those with dementia

by RAND CorporationCredit: CC0 Public DomainNearly a third of Americans who arranged for paid care for an older person or someone with dementia employed workers who were not hired through a regul

Updated on: July 01,2024

Nearly a third of Americans use gray market caregivers to aid the elderly and those with dementia

by RAND CorporationCredit: CC0 Public DomainNearly a third of Americans who arranged for paid care for an older person or someone with dementia employed workers who were not hired through a regul

Updated on:July 01,2024

Study reveals link between playing contact sports and parkinsonism in individuals with chronic traumatic encephalopathy

byBoston University School of MedicineCredit: Pixabay/CC0 Public DomainThe largest study of CTE to date has found a new link between playing contact sports, chronic traumatic encephalopathy (CTE

Updated on: July 17,2024

Study reveals link between playing contact sports and parkinsonism in individuals with chronic traumatic encephalopathy

byBoston University School of MedicineCredit: Pixabay/CC0 Public DomainThe largest study of CTE to date has found a new link between playing contact sports, chronic traumatic encephalopathy (CTE

Updated on:July 17,2024

Alzheimer's missing link ID'd, answering what tips brain's decline

by Washington University School of MedicineIn Alzheimer's, amyloid clumps (blue) develop first in the brain, followed by tangles of the protein tau (red). Tau is associated with memory loss a

Updated on: April 20,2024

Alzheimer's missing link ID'd, answering what tips brain's decline

by Washington University School of MedicineIn Alzheimer's, amyloid clumps (blue) develop first in the brain, followed by tangles of the protein tau (red). Tau is associated with memory loss a

Updated on:April 20,2024

Midbrain dopamine neurons can retain short-term memories, study shows

byRIKENIdentifying midbrain dopaminergic and GABAergic neurons. Credit:(2024). DOI: 10.7554/eLife.89743.2Dopamine neurons in the midbrain are involved in storing short-term memories—a func

Updated on: July 05,2024

Midbrain dopamine neurons can retain short-term memories, study shows

byRIKENIdentifying midbrain dopaminergic and GABAergic neurons. Credit:(2024). DOI: 10.7554/eLife.89743.2Dopamine neurons in the midbrain are involved in storing short-term memories—a func

Updated on:July 05,2024

Study finds tumor growth fueled by nucleotide salvage

byUTSouthwestern Medical CenterGraphical abstract. Credit:Cell(2024). DOI: 10.1016/j.cell.2024.05.011Cancer cells salvage purine nucleotides to fuel tumor growth, including pur

Updated on: August 01,2024

Study finds tumor growth fueled by nucleotide salvage

byUTSouthwestern Medical CenterGraphical abstract. Credit:Cell(2024). DOI: 10.1016/j.cell.2024.05.011Cancer cells salvage purine nucleotides to fuel tumor growth, including pur

Updated on:August 01,2024

Personalized stem cell model offers fast, individualized drug testing for amyotrophic lateral sclerosis

by International Society for Stem Cell ResearchThe technique for inducing differentiation of human motor neurons used in this paper clearly shows neuronal electrical activity. Credit: Satoru MorimotoA

Updated on: January 18,2025

Personalized stem cell model offers fast, individualized drug testing for amyotrophic lateral sclerosis

by International Society for Stem Cell ResearchThe technique for inducing differentiation of human motor neurons used in this paper clearly shows neuronal electrical activity. Credit: Satoru MorimotoA

Updated on:January 18,2025

Study finds how Alzheimer's-associated protein tangles spread through the brain

by Massachusetts General HospitalDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.Massachusetts General Hospital (MGH) investigators have discovered

Updated on: February 26,2024

Study finds how Alzheimer's-associated protein tangles spread through the brain

by Massachusetts General HospitalDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.Massachusetts General Hospital (MGH) investigators have discovered

Updated on:February 26,2024

How developing neurons build 'mini-computers' for increased computational power

by Netherlands Institute for Neuroscience - KNAWFigure dendritic domains. Credit: Netherlands Institute for NeuroscienceA new mouse study from the Netherlands Institute for Neuroscience (NIN) reveals

Updated on: July 31,2024

How developing neurons build 'mini-computers' for increased computational power

by Netherlands Institute for Neuroscience - KNAWFigure dendritic domains. Credit: Netherlands Institute for NeuroscienceA new mouse study from the Netherlands Institute for Neuroscience (NIN) reveals

Updated on:July 31,2024

P-glycoprotein removes Alzheimer's-associated toxin from the brain

by Southern Methodist University(A) The first frame of SMU's simulation shows amyloid-β bound to the drug binding domains of P-gp. (B) The final frame of the same simulation shows P-gp pushin

Updated on: April 01,2024

P-glycoprotein removes Alzheimer's-associated toxin from the brain

by Southern Methodist University(A) The first frame of SMU's simulation shows amyloid-β bound to the drug binding domains of P-gp. (B) The final frame of the same simulation shows P-gp pushin

Updated on:April 01,2024

Study finds long-term stroke survival improving, but racial disparities remain

byUniversity of CincinnatiCredit: Pixabay/CC0 Public DomainOverall rates of long-term survival following stroke are improving, but Black individuals experience worse long-term outcomes compared

Updated on: July 17,2024

Study finds long-term stroke survival improving, but racial disparities remain

byUniversity of CincinnatiCredit: Pixabay/CC0 Public DomainOverall rates of long-term survival following stroke are improving, but Black individuals experience worse long-term outcomes compared

Updated on:July 17,2024