Drug discovery paradigm targets Tau protein aggregation linked to the Alzheimer's disease

by Bentham Science PublishersDementia and other tauopathies, most notably Alzheimer's disease, embody a class of neurodegenerative diseases associated with the aggregation of the Tau protein in th

Updated on: February 28,2024

Drug discovery paradigm targets Tau protein aggregation linked to the Alzheimer's disease

by Bentham Science PublishersDementia and other tauopathies, most notably Alzheimer's disease, embody a class of neurodegenerative diseases associated with the aggregation of the Tau protein in th

Updated on:February 28,2024

Women may keep verbal memory skills longer than men in the early stages of Alzheimer's

by American Academy of NeurologyDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.Women may have a better memory for words than men despite evidence o

Updated on: February 28,2024

Women may keep verbal memory skills longer than men in the early stages of Alzheimer's

by American Academy of NeurologyDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.Women may have a better memory for words than men despite evidence o

Updated on:February 28,2024

P-glycoprotein removes Alzheimer's-associated toxin from the brain

by Southern Methodist University(A) The first frame of SMU's simulation shows amyloid-β bound to the drug binding domains of P-gp. (B) The final frame of the same simulation shows P-gp pushin

Updated on: April 01,2024

P-glycoprotein removes Alzheimer's-associated toxin from the brain

by Southern Methodist University(A) The first frame of SMU's simulation shows amyloid-β bound to the drug binding domains of P-gp. (B) The final frame of the same simulation shows P-gp pushin

Updated on:April 01,2024

Review finds no benefit to aspirin for preserving cognitive function

by WileyCoated aspirin tablets. Image: Wikimedia Commons.An analysis of published studies found no evidence that low- dose aspirin buffers against cognitive decline or dementia or improves cognit

Updated on: March 09,2024

Review finds no benefit to aspirin for preserving cognitive function

by WileyCoated aspirin tablets. Image: Wikimedia Commons.An analysis of published studies found no evidence that low- dose aspirin buffers against cognitive decline or dementia or improves cognit

Updated on:March 09,2024

Investigating plasma levels as a biomarker for Alzheimer's disease

by Bentham Science PublishersA Centre for Healthy Brain Ageing (CHeBA) paper published inCurrent Alzheimer Researchpresents the first detailed study of the relationship between plasma leve

Updated on: February 28,2024

Investigating plasma levels as a biomarker for Alzheimer's disease

by Bentham Science PublishersA Centre for Healthy Brain Ageing (CHeBA) paper published inCurrent Alzheimer Researchpresents the first detailed study of the relationship between plasma leve

Updated on:February 28,2024

New cases of dementia in the UK fall by 20 percent over two decades

by University of CambridgeThe UK has seen a 20% fall in the incidence of dementia over the past two decades, according to new research from England, led by the University of Cambridge, leading to

Updated on: February 28,2024

New cases of dementia in the UK fall by 20 percent over two decades

by University of CambridgeThe UK has seen a 20% fall in the incidence of dementia over the past two decades, according to new research from England, led by the University of Cambridge, leading to

Updated on:February 28,2024

Alzheimer's disease: How amyloid aggregates alter neuronal function

by CNRSRat hippocampal neurons in primary culture, showing a fluorescent soluble protein (left) and trajectories corresponding to the movement of the glutamate receptors on its surface, measured

Updated on: April 08,2024

Alzheimer's disease: How amyloid aggregates alter neuronal function

by CNRSRat hippocampal neurons in primary culture, showing a fluorescent soluble protein (left) and trajectories corresponding to the movement of the glutamate receptors on its surface, measured

Updated on:April 08,2024

Advanced infant brain development may not always be a good thing

by Mallory Locklear,Yale UniversityOverview of study design. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-54657-5The human brain undergoes significant development duri

Updated on: December 16,2024

Advanced infant brain development may not always be a good thing

by Mallory Locklear,Yale UniversityOverview of study design. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-54657-5The human brain undergoes significant development duri

Updated on:December 16,2024

Facial expressions of pain can be predicted from brain activity, researchers show

by Béatrice St-Cyr-Leroux,University of MontrealSpatial similarity between the FEPS and other pain-related signatures. Credit:(2024). DOI: 10.7554/eLife.87962.2Stubbing your toe on a table

Updated on: December 17,2024

Facial expressions of pain can be predicted from brain activity, researchers show

by Béatrice St-Cyr-Leroux,University of MontrealSpatial similarity between the FEPS and other pain-related signatures. Credit:(2024). DOI: 10.7554/eLife.87962.2Stubbing your toe on a table

Updated on:December 17,2024

Degrading modified proteins could treat Alzheimer's, other 'undruggable' diseases

by American Chemical SocietyGraphical abstract. Credit:ACS Central Science(2023). DOI: 10.1021/acscentsci.2c01369Certain diseases, including Alzheimer's, are currently considered

Updated on: June 24,2024

Degrading modified proteins could treat Alzheimer's, other 'undruggable' diseases

by American Chemical SocietyGraphical abstract. Credit:ACS Central Science(2023). DOI: 10.1021/acscentsci.2c01369Certain diseases, including Alzheimer's, are currently considered

Updated on:June 24,2024

FAU site for first US clinical trial for Lewy Body dementia

by Florida Atlantic UniversityThe South Florida clinical trial is directed by one of the world's leading neuroscientists and an expert on LBD, James E. Galvin, M.D., M.P.H., a professor of cl

Updated on: February 28,2024

FAU site for first US clinical trial for Lewy Body dementia

by Florida Atlantic UniversityThe South Florida clinical trial is directed by one of the world's leading neuroscientists and an expert on LBD, James E. Galvin, M.D., M.P.H., a professor of cl

Updated on:February 28,2024

Holiday stress can lead Alzheimer's patients and those with dementia to go missing

by Shelia PooleCredit: Pixabay/CC0 Public DomainHolidays are a time for families and friends to gather, but for older people with Alzheimer's disease and other dementias, it can cause so much stre

Updated on: February 01,2025

Holiday stress can lead Alzheimer's patients and those with dementia to go missing

by Shelia PooleCredit: Pixabay/CC0 Public DomainHolidays are a time for families and friends to gather, but for older people with Alzheimer's disease and other dementias, it can cause so much stre

Updated on:February 01,2025