Drug discovery paradigm targets Tau protein aggregation linked to the Alzheimer's disease

by Bentham Science PublishersDementia and other tauopathies, most notably Alzheimer's disease, embody a class of neurodegenerative diseases associated with the aggregation of the Tau protein in th

Updated on: February 28,2024

Drug discovery paradigm targets Tau protein aggregation linked to the Alzheimer's disease

by Bentham Science PublishersDementia and other tauopathies, most notably Alzheimer's disease, embody a class of neurodegenerative diseases associated with the aggregation of the Tau protein in th

Updated on:February 28,2024

Dementia spreads via connected brain networks

by University of California, San FranciscoCredit: CC0 Public DomainIn a new study, UC San Francisco scientists used maps of brain connections to predict how brain atrophy would spread in individu

Updated on: May 11,2024

Dementia spreads via connected brain networks

by University of California, San FranciscoCredit: CC0 Public DomainIn a new study, UC San Francisco scientists used maps of brain connections to predict how brain atrophy would spread in individu

Updated on:May 11,2024

Possible pathway to new therapy for Alzheimer's disease

by Boston University School of MedicineResearchers have uncovered an enzyme and a biochemical pathway they believe may lead to the identification of drugs that could inhibit the production of bet

Updated on: March 07,2024

Possible pathway to new therapy for Alzheimer's disease

by Boston University School of MedicineResearchers have uncovered an enzyme and a biochemical pathway they believe may lead to the identification of drugs that could inhibit the production of bet

Updated on:March 07,2024

The brain-heart connection: Understanding a powerful tie that works both ways

Updated on: September 26,2025

The brain-heart connection: Understanding a powerful tie that works both ways

Updated on:September 26,2025

Investigating plasma levels as a biomarker for Alzheimer's disease

by Bentham Science PublishersA Centre for Healthy Brain Ageing (CHeBA) paper published inCurrent Alzheimer Researchpresents the first detailed study of the relationship between plasma leve

Updated on: February 28,2024

Investigating plasma levels as a biomarker for Alzheimer's disease

by Bentham Science PublishersA Centre for Healthy Brain Ageing (CHeBA) paper published inCurrent Alzheimer Researchpresents the first detailed study of the relationship between plasma leve

Updated on:February 28,2024

Preventing Alzheimer's in African-Americans by strengthening the brain

by Rutgers UniversityZumba class at New Hope Baptist Church in Newark, N.J. Credit: Dr. Mark GluckA major effort is underway to reduce the risk of Alzheimer's disease and other forms of demen

Updated on: February 28,2024

Preventing Alzheimer's in African-Americans by strengthening the brain

by Rutgers UniversityZumba class at New Hope Baptist Church in Newark, N.J. Credit: Dr. Mark GluckA major effort is underway to reduce the risk of Alzheimer's disease and other forms of demen

Updated on:February 28,2024

Unraveling Alzheimer's catalysts as weavers of amyloid β fibrils

by National Institutes of Natural Sciences(A) On the neuronal cell membrane, Aβ molecules adopt a "U"-shaped conformation, allining alternately on the membrane surface to form two layer

Updated on: July 01,2024

Unraveling Alzheimer's catalysts as weavers of amyloid β fibrils

by National Institutes of Natural Sciences(A) On the neuronal cell membrane, Aβ molecules adopt a "U"-shaped conformation, allining alternately on the membrane surface to form two layer

Updated on:July 01,2024

Review finds no benefit to aspirin for preserving cognitive function

by WileyCoated aspirin tablets. Image: Wikimedia Commons.An analysis of published studies found no evidence that low- dose aspirin buffers against cognitive decline or dementia or improves cognit

Updated on: March 09,2024

Review finds no benefit to aspirin for preserving cognitive function

by WileyCoated aspirin tablets. Image: Wikimedia Commons.An analysis of published studies found no evidence that low- dose aspirin buffers against cognitive decline or dementia or improves cognit

Updated on:March 09,2024

Women with ovarian removal have unique risk and resilience factors for Alzheimer disease, research finds

byUniversity of TorontoCredit: Pixabay/CC0 Public DomainResearch published by a team of researchers from the University of Toronto in collaboration with colleagues from the University of Alberta

Updated on: December 11,2024

Women with ovarian removal have unique risk and resilience factors for Alzheimer disease, research finds

byUniversity of TorontoCredit: Pixabay/CC0 Public DomainResearch published by a team of researchers from the University of Toronto in collaboration with colleagues from the University of Alberta

Updated on:December 11,2024

Potential noninvasive treatment for Alzheimer's disease

by University of QueenslandCredit: University of QueenslandUltrasound can overcome some of the detrimental effects of aging and dementia without the need to cross the blood-brain barrier, researc

Updated on: April 10,2024

Potential noninvasive treatment for Alzheimer's disease

by University of QueenslandCredit: University of QueenslandUltrasound can overcome some of the detrimental effects of aging and dementia without the need to cross the blood-brain barrier, researc

Updated on:April 10,2024

Stroke associated with accelerated long-term cognitive decline

by Helena Hudson,University of New South WalesCredit: Pixabay/CC0 Public DomainNew evidence from the Centre for Healthy Brain Ageing (CHeBA) indicates that older adults who experience a stroke f

Updated on: October 21,2024

Stroke associated with accelerated long-term cognitive decline

by Helena Hudson,University of New South WalesCredit: Pixabay/CC0 Public DomainNew evidence from the Centre for Healthy Brain Ageing (CHeBA) indicates that older adults who experience a stroke f

Updated on:October 21,2024

P-glycoprotein removes Alzheimer's-associated toxin from the brain

by Southern Methodist University(A) The first frame of SMU's simulation shows amyloid-β bound to the drug binding domains of P-gp. (B) The final frame of the same simulation shows P-gp pushin

Updated on: April 01,2024

P-glycoprotein removes Alzheimer's-associated toxin from the brain

by Southern Methodist University(A) The first frame of SMU's simulation shows amyloid-β bound to the drug binding domains of P-gp. (B) The final frame of the same simulation shows P-gp pushin

Updated on:April 01,2024