Study finds tumor growth fueled by nucleotide salvage

byUTSouthwestern Medical CenterGraphical abstract. Credit:Cell(2024). DOI: 10.1016/j.cell.2024.05.011Cancer cells salvage purine nucleotides to fuel tumor growth, including pur

Updated on: August 01,2024

Study finds tumor growth fueled by nucleotide salvage

byUTSouthwestern Medical CenterGraphical abstract. Credit:Cell(2024). DOI: 10.1016/j.cell.2024.05.011Cancer cells salvage purine nucleotides to fuel tumor growth, including pur

Updated on:August 01,2024

Alzheimer's missing link ID'd, answering what tips brain's decline

by Washington University School of MedicineIn Alzheimer's, amyloid clumps (blue) develop first in the brain, followed by tangles of the protein tau (red). Tau is associated with memory loss a

Updated on: April 20,2024

Alzheimer's missing link ID'd, answering what tips brain's decline

by Washington University School of MedicineIn Alzheimer's, amyloid clumps (blue) develop first in the brain, followed by tangles of the protein tau (red). Tau is associated with memory loss a

Updated on:April 20,2024

A toxic byproduct of hemoglobin could provide treatments for Creutzfeldt-Jakob Disease

by Case Western Reserve UniversityScientists at Case Western Reserve University School of Medicine have identified a novel mechanism that could be used to protect the brain from damage due to str

Updated on: February 28,2024

A toxic byproduct of hemoglobin could provide treatments for Creutzfeldt-Jakob Disease

by Case Western Reserve UniversityScientists at Case Western Reserve University School of Medicine have identified a novel mechanism that could be used to protect the brain from damage due to str

Updated on:February 28,2024

Fructose made in the brain could be a mechanism driving Alzheimer's disease

by CU Anschutz Medical CampusCredit: Pixabay/CC0 Public DomainNew research released from the University of Colorado Anschutz Medical Campus proposes that Alzheimer's disease may be driven by

Updated on: May 18,2024

Fructose made in the brain could be a mechanism driving Alzheimer's disease

by CU Anschutz Medical CampusCredit: Pixabay/CC0 Public DomainNew research released from the University of Colorado Anschutz Medical Campus proposes that Alzheimer's disease may be driven by

Updated on:May 18,2024

New drug targets for Alzheimer's identified from cerebrospinal fluid

by Mark Reynolds,Washington University School of MedicineCellular localization of immune and lysosomal proteins. Credit:Nature Genetics(2024). DOI: 10.1038/s41588-024-01972-8A multit

Updated on: November 22,2024

New drug targets for Alzheimer's identified from cerebrospinal fluid

by Mark Reynolds,Washington University School of MedicineCellular localization of immune and lysosomal proteins. Credit:Nature Genetics(2024). DOI: 10.1038/s41588-024-01972-8A multit

Updated on:November 22,2024

Old drug offers new hope to treat Alzheimer's disease

by Gladstone InstitutesVarious pills. Credit: WikipediaScientists from the Gladstone Institutes have discovered that salsalate, a drug used to treat rheumatoid arthritis, effectively reversed tau

Updated on: February 26,2024

Old drug offers new hope to treat Alzheimer's disease

by Gladstone InstitutesVarious pills. Credit: WikipediaScientists from the Gladstone Institutes have discovered that salsalate, a drug used to treat rheumatoid arthritis, effectively reversed tau

Updated on:February 26,2024

Does fungus cause Alzheimer's?

Diagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.Traces of fungus have been discovered in the brains of Alzheimer's sufferers, researchers said Thursd

Updated on: February 26,2024

Does fungus cause Alzheimer's?

Diagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.Traces of fungus have been discovered in the brains of Alzheimer's sufferers, researchers said Thursd

Updated on:February 26,2024

Researchers identify 'neurostatin' that may reduce the risk of Alzheimer's disease

by University of CambridgeDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.Researchers have identified a drug that targets the first step in the toxi

Updated on: February 28,2024

Researchers identify 'neurostatin' that may reduce the risk of Alzheimer's disease

by University of CambridgeDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.Researchers have identified a drug that targets the first step in the toxi

Updated on:February 28,2024

Alzheimer's: New study supports amyloid hypothesis but suggests alternative treatment

by Columbia UniversityCREB3L2-ATF4 up-regulation in β-amyloid pathology 5xFAD model. In vivo detection and quantification of CREB3L2-ATF4 dimers by PLA in the dentate gyrus of 10-week-old 5xFAD o

Updated on: April 10,2024

Alzheimer's: New study supports amyloid hypothesis but suggests alternative treatment

by Columbia UniversityCREB3L2-ATF4 up-regulation in β-amyloid pathology 5xFAD model. In vivo detection and quantification of CREB3L2-ATF4 dimers by PLA in the dentate gyrus of 10-week-old 5xFAD o

Updated on:April 10,2024

How Alzheimer's disease spreads throughout the brain – new study

by Thomas E Cope,The ConversationHarmful tau protein spreads through networks.Alzheimer's disease is a devastating brain illness that affects anestimated 47m peopleworldwide. It

Updated on: April 10,2024

How Alzheimer's disease spreads throughout the brain – new study

by Thomas E Cope,The ConversationHarmful tau protein spreads through networks.Alzheimer's disease is a devastating brain illness that affects anestimated 47m peopleworldwide. It

Updated on:April 10,2024

How developing neurons build 'mini-computers' for increased computational power

by Netherlands Institute for Neuroscience - KNAWFigure dendritic domains. Credit: Netherlands Institute for NeuroscienceA new mouse study from the Netherlands Institute for Neuroscience (NIN) reveals

Updated on: July 31,2024

How developing neurons build 'mini-computers' for increased computational power

by Netherlands Institute for Neuroscience - KNAWFigure dendritic domains. Credit: Netherlands Institute for NeuroscienceA new mouse study from the Netherlands Institute for Neuroscience (NIN) reveals

Updated on:July 31,2024

Essential nutrient may help fight Alzheimer's across generations

by Richard Harth,Arizona State UniversityMice with AD-like symptoms receiving supplemental levels of choline in the womb improved their spatial memory. A second generation bred from these cholin

Updated on: April 29,2024

Essential nutrient may help fight Alzheimer's across generations

by Richard Harth,Arizona State UniversityMice with AD-like symptoms receiving supplemental levels of choline in the womb improved their spatial memory. A second generation bred from these cholin

Updated on:April 29,2024