An anti-apoE4 specific monoclonal antibody counteracts the pathological effects of apoE4 in vivo

by Bentham Science PublishersThe pathological hallmarks of Alzheimer's disease (AD), viz defective Aβ and tau proteins, have been the center of AD-directed therapeutic studies. Although this appro

Updated on: March 07,2024

An anti-apoE4 specific monoclonal antibody counteracts the pathological effects of apoE4 in vivo

by Bentham Science PublishersThe pathological hallmarks of Alzheimer's disease (AD), viz defective Aβ and tau proteins, have been the center of AD-directed therapeutic studies. Although this appro

Updated on:March 07,2024

Researchers identify the 'broken gate' causing unstoppable brain signals in severe childhood epilepsy

by Florey Institute of Neuroscience and Mental Health2D transmembrane topology of the wild-type (WT) Nav1.2 channel showing 27 domains DI−DIV and amino acid residues N1662 (cytosolic side of S5DIV) an

Updated on: August 03,2024

Researchers identify the 'broken gate' causing unstoppable brain signals in severe childhood epilepsy

by Florey Institute of Neuroscience and Mental Health2D transmembrane topology of the wild-type (WT) Nav1.2 channel showing 27 domains DI−DIV and amino acid residues N1662 (cytosolic side of S5DIV) an

Updated on:August 03,2024

Experience of racism linked with poorer memory and thinking

by Alzheimer's Research UKCredit: Unsplash/CC0 Public DomainResearch presented today (Monday 1 August) at the 2022 Alzheimer's Association International Conference (AAIC) in San Diego acr

Updated on: March 09,2024

Experience of racism linked with poorer memory and thinking

by Alzheimer's Research UKCredit: Unsplash/CC0 Public DomainResearch presented today (Monday 1 August) at the 2022 Alzheimer's Association International Conference (AAIC) in San Diego acr

Updated on:March 09,2024

Experiments show untrained patient with prosthetic hand can tell objects apart by touch

Updated on: March 03,2025

Experiments show untrained patient with prosthetic hand can tell objects apart by touch

Updated on:March 03,2025

Modulation of brain cholesterol: A new line of research in Alzheimer's disease treatment?

by Institut National de la Sante et de la Recherche MedicaleFluorescent labelling of the Tau protein in a hNT human cell. Credit: ©Inserm/U837We have known for some years that Alzheimer&#39

Updated on: February 26,2024

Modulation of brain cholesterol: A new line of research in Alzheimer's disease treatment?

by Institut National de la Sante et de la Recherche MedicaleFluorescent labelling of the Tau protein in a hNT human cell. Credit: ©Inserm/U837We have known for some years that Alzheimer&#39

Updated on:February 26,2024

Degrading modified proteins could treat Alzheimer's, other 'undruggable' diseases

by American Chemical SocietyGraphical abstract. Credit:ACS Central Science(2023). DOI: 10.1021/acscentsci.2c01369Certain diseases, including Alzheimer's, are currently considered

Updated on: June 24,2024

Degrading modified proteins could treat Alzheimer's, other 'undruggable' diseases

by American Chemical SocietyGraphical abstract. Credit:ACS Central Science(2023). DOI: 10.1021/acscentsci.2c01369Certain diseases, including Alzheimer's, are currently considered

Updated on:June 24,2024

Rehabilitation approach combines spinal and hip stimulation to improve walking speed in patients with stroke

Updated on: September 02,2025

Rehabilitation approach combines spinal and hip stimulation to improve walking speed in patients with stroke

Updated on:September 02,2025

Body's immune system may play larger role in Alzheimer's disease than thought

by University of California, IrvineMicroglia (green) surround an amyloid plaque (blue) in the brain of an Alzheimer's disease mouse model. UCI researchers have shown that endogenous mouse ant

Updated on: February 28,2024

Body's immune system may play larger role in Alzheimer's disease than thought

by University of California, IrvineMicroglia (green) surround an amyloid plaque (blue) in the brain of an Alzheimer's disease mouse model. UCI researchers have shown that endogenous mouse ant

Updated on:February 28,2024

Mesh-like scaffold is disordered in Alzheimer's-affected cells

by Will Sansom,University of Texas Health Science Center at San AntonioBrain cells from a fruit fly model of Alzheimer's disease were compared to healthy brain cells to show a type of dysfun

Updated on: February 27,2024

Mesh-like scaffold is disordered in Alzheimer's-affected cells

by Will Sansom,University of Texas Health Science Center at San AntonioBrain cells from a fruit fly model of Alzheimer's disease were compared to healthy brain cells to show a type of dysfun

Updated on:February 27,2024

'Lesser of two evils' argument used to defend antipsychotic overuse for dementia

by University of ReadingCredit: University of ReadingThe increasing use of antipsychotic drugs to manage dementia in care homes has been explained by some practitioners as "the lesser of two

Updated on: March 09,2024

'Lesser of two evils' argument used to defend antipsychotic overuse for dementia

by University of ReadingCredit: University of ReadingThe increasing use of antipsychotic drugs to manage dementia in care homes has been explained by some practitioners as "the lesser of two

Updated on:March 09,2024

Extending use of existing Alzheimer's drug could delay move into nursing home

by Alzheimer's Research UKDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.Newly-released follow-up analysis from a 2012 clinical trial led by a

Updated on: February 26,2024

Extending use of existing Alzheimer's drug could delay move into nursing home

by Alzheimer's Research UKDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.Newly-released follow-up analysis from a 2012 clinical trial led by a

Updated on:February 26,2024

Flotillin is a novel diagnostic blood marker of Alzheimer's disease

by Nagoya City UniversityFlotillin in serum collected from patients with AD and non-AD cases was examined by western blot analysis. Intensity of flotillin bands was quantified using Image J. A, The re

Updated on: March 30,2024

Flotillin is a novel diagnostic blood marker of Alzheimer's disease

by Nagoya City UniversityFlotillin in serum collected from patients with AD and non-AD cases was examined by western blot analysis. Intensity of flotillin bands was quantified using Image J. A, The re

Updated on:March 30,2024