Clinical trial suggests new drug candidate for spinocerebellar ataxia may offer certain therapeutic benefits

byNiigata UniversityL-arginine inhibits the aggregation of polyglutamine proteins in neuronal cells. Credit: Niigata UniversityA team has conducted a trial on the efficacy and safety of L-argini

Updated on: December 18,2024

Clinical trial suggests new drug candidate for spinocerebellar ataxia may offer certain therapeutic benefits

byNiigata UniversityL-arginine inhibits the aggregation of polyglutamine proteins in neuronal cells. Credit: Niigata UniversityA team has conducted a trial on the efficacy and safety of L-argini

Updated on:December 18,2024

Towards better management of disinhibition in frontotemporal dementia

by Marie Simon,Paris Brain InstituteReconstruction of a waiting room for the ECOCAPTURE study. Credit: FrontLab, Paris Brain InstituteDisinhibition is one of the main symptoms of the behavioral

Updated on: June 05,2024

Towards better management of disinhibition in frontotemporal dementia

by Marie Simon,Paris Brain InstituteReconstruction of a waiting room for the ECOCAPTURE study. Credit: FrontLab, Paris Brain InstituteDisinhibition is one of the main symptoms of the behavioral

Updated on:June 05,2024

Super ager brains contain 'super neurons'

by Northwestern UniversityCredit: Pixabay/CC0 Public DomainNeurons in an area of the brain responsible for memory (known as the entorhinal cortex) were significantly larger in super agers (80 yea

Updated on: February 03,2024

Super ager brains contain 'super neurons'

by Northwestern UniversityCredit: Pixabay/CC0 Public DomainNeurons in an area of the brain responsible for memory (known as the entorhinal cortex) were significantly larger in super agers (80 yea

Updated on:February 03,2024

How does the brain keep calm? Insight into brain stability and the key role of NMDA receptors

byTel-Aviv UniversityGraphical abstract. Credit:Neuron(2024). DOI: 10.1016/j.neuron.2024.10.014Researchers at Tel Aviv University have made a fundamental discovery: the NMDA receptor

Updated on: November 28,2024

How does the brain keep calm? Insight into brain stability and the key role of NMDA receptors

byTel-Aviv UniversityGraphical abstract. Credit:Neuron(2024). DOI: 10.1016/j.neuron.2024.10.014Researchers at Tel Aviv University have made a fundamental discovery: the NMDA receptor

Updated on:November 28,2024

Memory may be preserved in condition with brain changes similar to Alzheimer's disease

by American Academy of NeurologyCredit: Unsplash/CC0 Public DomainPrimary progressive aphasia is a rare neurodegenerative condition characterized by prominent language problems that worsen over t

Updated on: June 18,2024

Memory may be preserved in condition with brain changes similar to Alzheimer's disease

by American Academy of NeurologyCredit: Unsplash/CC0 Public DomainPrimary progressive aphasia is a rare neurodegenerative condition characterized by prominent language problems that worsen over t

Updated on:June 18,2024

New insights into the formation of toxic protein clumps in Alzheimer's disease

byForschungszentrum JuelichSmall Aβ oligomers (left: cryo-electron microscopy) are clumps consisting of just a few Aβ molecules. They cluster together to form short, worm-like structures known a

Updated on: April 18,2024

New insights into the formation of toxic protein clumps in Alzheimer's disease

byForschungszentrum JuelichSmall Aβ oligomers (left: cryo-electron microscopy) are clumps consisting of just a few Aβ molecules. They cluster together to form short, worm-like structures known a

Updated on:April 18,2024

IL-21 protein a key part of immune response to central nervous system infections

by Zachary Sweger,Pennsylvania State UniversityT cells infiltrating brains of MuPyV-infected mice captured in the Lukacher lab. Credit: Penn StateResearchers at Penn State College of Medicine no

Updated on: April 16,2024

IL-21 protein a key part of immune response to central nervous system infections

by Zachary Sweger,Pennsylvania State UniversityT cells infiltrating brains of MuPyV-infected mice captured in the Lukacher lab. Credit: Penn StateResearchers at Penn State College of Medicine no

Updated on:April 16,2024

Disorders of consciousness: Increasing awareness of advances in brain injury medicine

by IOS PressCredit: Pixabay/CC0 Public DomainEmerging trends and new developments in the care and management of patients with disorders of consciousness (DoC) are increasingly focused on a multid

Updated on: March 19,2024

Disorders of consciousness: Increasing awareness of advances in brain injury medicine

by IOS PressCredit: Pixabay/CC0 Public DomainEmerging trends and new developments in the care and management of patients with disorders of consciousness (DoC) are increasingly focused on a multid

Updated on:March 19,2024

Study confirms cognitive deficits in people with the rare disease MOGAD

by Stefan Zorn, Medizinische Hochschule HannoverMean z-scores of neuropsychological tests at baseline (patients <60 years). PASAT, Paced Auditory Serial Addition Task; SDMT, Symbol Digit Modalities

Updated on: November 12,2024

Study confirms cognitive deficits in people with the rare disease MOGAD

by Stefan Zorn, Medizinische Hochschule HannoverMean z-scores of neuropsychological tests at baseline (patients <60 years). PASAT, Paced Auditory Serial Addition Task; SDMT, Symbol Digit Modalities

Updated on:November 12,2024

A multi-faceted approach to improve Alzheimer's diagnosis

by David Bradley,InderscienceCredit: Pixabay/CC0 Public DomainAreviewin theInternational Journal of Medical Engineering and Informaticshas surveyed current early detectio

Updated on: March 02,2024

A multi-faceted approach to improve Alzheimer's diagnosis

by David Bradley,InderscienceCredit: Pixabay/CC0 Public DomainAreviewin theInternational Journal of Medical Engineering and Informaticshas surveyed current early detectio

Updated on:March 02,2024

Alzheimer's disease risk gene APOE4 impairs function of brain immune cells

by University of Eastern FinlandThe induced pluripotent stem cell (iPSC) -derived microglia demonstrate that apolipoprotein E4 (APOE4) has a profound impact on several functions of human brain im

Updated on: April 08,2024

Alzheimer's disease risk gene APOE4 impairs function of brain immune cells

by University of Eastern FinlandThe induced pluripotent stem cell (iPSC) -derived microglia demonstrate that apolipoprotein E4 (APOE4) has a profound impact on several functions of human brain im

Updated on:April 08,2024

Can robots help care for people with dementia?

by George Wigmore,City University LondonCredit: AI-generated imageAs our populations continue to age the issue of how we deliver care to the elderly continues to be an incredibly important issue

Updated on: June 11,2024

Can robots help care for people with dementia?

by George Wigmore,City University LondonCredit: AI-generated imageAs our populations continue to age the issue of how we deliver care to the elderly continues to be an incredibly important issue

Updated on:June 11,2024