IL-21 protein a key part of immune response to central nervous system infections

by Zachary Sweger,Pennsylvania State UniversityT cells infiltrating brains of MuPyV-infected mice captured in the Lukacher lab. Credit: Penn StateResearchers at Penn State College of Medicine no

Updated on: April 16,2024

IL-21 protein a key part of immune response to central nervous system infections

by Zachary Sweger,Pennsylvania State UniversityT cells infiltrating brains of MuPyV-infected mice captured in the Lukacher lab. Credit: Penn StateResearchers at Penn State College of Medicine no

Updated on:April 16,2024

Patients with Alzheimer's dementia and related disorders who also have delirium incur greater health care costs

by Brigham and Women's HospitalCredit: Pixabay/CC0 Public DomainAlzheimer's Dementia and Related Disorders (ADRD) affects upwards of 5 million people in the United States, with no known t

Updated on: June 07,2024

Patients with Alzheimer's dementia and related disorders who also have delirium incur greater health care costs

by Brigham and Women's HospitalCredit: Pixabay/CC0 Public DomainAlzheimer's Dementia and Related Disorders (ADRD) affects upwards of 5 million people in the United States, with no known t

Updated on:June 07,2024

Study confirms cognitive deficits in people with the rare disease MOGAD

by Stefan Zorn, Medizinische Hochschule HannoverMean z-scores of neuropsychological tests at baseline (patients <60 years). PASAT, Paced Auditory Serial Addition Task; SDMT, Symbol Digit Modalities

Updated on: November 12,2024

Study confirms cognitive deficits in people with the rare disease MOGAD

by Stefan Zorn, Medizinische Hochschule HannoverMean z-scores of neuropsychological tests at baseline (patients <60 years). PASAT, Paced Auditory Serial Addition Task; SDMT, Symbol Digit Modalities

Updated on:November 12,2024

Blood vessel breakdown linked with Alzheimer's disease

by Centenary InstituteSGP expression in mouse models of AD. Representative images of SGP expression in APP/PS1 (A) and APP23 (B) compared to wildtype (WT) mice over different stages of plaque dev

Updated on: March 02,2024

Blood vessel breakdown linked with Alzheimer's disease

by Centenary InstituteSGP expression in mouse models of AD. Representative images of SGP expression in APP/PS1 (A) and APP23 (B) compared to wildtype (WT) mice over different stages of plaque dev

Updated on:March 02,2024

Super ager brains contain 'super neurons'

by Northwestern UniversityCredit: Pixabay/CC0 Public DomainNeurons in an area of the brain responsible for memory (known as the entorhinal cortex) were significantly larger in super agers (80 yea

Updated on: February 03,2024

Super ager brains contain 'super neurons'

by Northwestern UniversityCredit: Pixabay/CC0 Public DomainNeurons in an area of the brain responsible for memory (known as the entorhinal cortex) were significantly larger in super agers (80 yea

Updated on:February 03,2024

Memory may be preserved in condition with brain changes similar to Alzheimer's disease

by American Academy of NeurologyCredit: Unsplash/CC0 Public DomainPrimary progressive aphasia is a rare neurodegenerative condition characterized by prominent language problems that worsen over t

Updated on: June 18,2024

Memory may be preserved in condition with brain changes similar to Alzheimer's disease

by American Academy of NeurologyCredit: Unsplash/CC0 Public DomainPrimary progressive aphasia is a rare neurodegenerative condition characterized by prominent language problems that worsen over t

Updated on:June 18,2024

Epigenetics blood markers can help understand dementia risk

byUniversity of ExeterOverview of the model generation. The model generation workflow consists of model training in the EXTEND and EMIF-AD cohorts using two different approaches. Credit:Al

Updated on: September 03,2024

Epigenetics blood markers can help understand dementia risk

byUniversity of ExeterOverview of the model generation. The model generation workflow consists of model training in the EXTEND and EMIF-AD cohorts using two different approaches. Credit:Al

Updated on:September 03,2024

ALS and dementia attacked by an RNA-hunting compound that recruits cell's own virus fighter

by The Scripps Research InstituteTo study the effectiveness of their compounds, the scientists directed cells from patients with ALS to become stem cells and then specialize into nerve cells. Cre

Updated on: June 14,2024

ALS and dementia attacked by an RNA-hunting compound that recruits cell's own virus fighter

by The Scripps Research InstituteTo study the effectiveness of their compounds, the scientists directed cells from patients with ALS to become stem cells and then specialize into nerve cells. Cre

Updated on:June 14,2024

Unexpected link found between 2 schizophrenia risk proteins

by Emily Caldwell,The Ohio State UniversityBehavioral alterations in MAP6−/−and Kv3.1−/−mice. Adult (3–6 months old) WT B6 (black bars), MAP6−/−(red bars), and Kv3.1−/−(g

Updated on: January 12,2024

Unexpected link found between 2 schizophrenia risk proteins

by Emily Caldwell,The Ohio State UniversityBehavioral alterations in MAP6−/−and Kv3.1−/−mice. Adult (3–6 months old) WT B6 (black bars), MAP6−/−(red bars), and Kv3.1−/−(g

Updated on:January 12,2024

First U.S. clinical trial using adult allogeneic stem cells to treat Alzheimer's disease

by Emory UniversityA new study to assess the safety, tolerability and preliminary efficacy of allogeneic stem cells in persons with mild to moderate dementia due to Alzheimer's disease (AD) i

Updated on: March 07,2024

First U.S. clinical trial using adult allogeneic stem cells to treat Alzheimer's disease

by Emory UniversityA new study to assess the safety, tolerability and preliminary efficacy of allogeneic stem cells in persons with mild to moderate dementia due to Alzheimer's disease (AD) i

Updated on:March 07,2024

How do we decide what to look at next? A computational model has the answer

byTechnical University of BerlinObject-based scanpath simulation in dynamic scenes. Credit: The image is derived from a frame of the field03 video of the VidCom dataset (Permission to Publish Co

Updated on: January 11,2024

How do we decide what to look at next? A computational model has the answer

byTechnical University of BerlinObject-based scanpath simulation in dynamic scenes. Credit: The image is derived from a frame of the field03 video of the VidCom dataset (Permission to Publish Co

Updated on:January 11,2024

Largest-ever genetic study of epilepsy finds possible therapeutic targets

by Ari Navetta,Broad Institute of MIT and HarvardEpilepsy genetic architecture from large-scale genetic association studies. Credit:Nature Neuroscience(2024). DOI: 10.1038/s41593-024

Updated on: October 09,2024

Largest-ever genetic study of epilepsy finds possible therapeutic targets

by Ari Navetta,Broad Institute of MIT and HarvardEpilepsy genetic architecture from large-scale genetic association studies. Credit:Nature Neuroscience(2024). DOI: 10.1038/s41593-024

Updated on:October 09,2024