Largest-ever genetic study of epilepsy finds possible therapeutic targets

by Ari Navetta,Broad Institute of MIT and HarvardEpilepsy genetic architecture from large-scale genetic association studies. Credit:Nature Neuroscience(2024). DOI: 10.1038/s41593-024

Updated on: October 09,2024

Largest-ever genetic study of epilepsy finds possible therapeutic targets

by Ari Navetta,Broad Institute of MIT and HarvardEpilepsy genetic architecture from large-scale genetic association studies. Credit:Nature Neuroscience(2024). DOI: 10.1038/s41593-024

Updated on:October 09,2024

Super ager brains contain 'super neurons'

by Northwestern UniversityCredit: Pixabay/CC0 Public DomainNeurons in an area of the brain responsible for memory (known as the entorhinal cortex) were significantly larger in super agers (80 yea

Updated on: February 03,2024

Super ager brains contain 'super neurons'

by Northwestern UniversityCredit: Pixabay/CC0 Public DomainNeurons in an area of the brain responsible for memory (known as the entorhinal cortex) were significantly larger in super agers (80 yea

Updated on:February 03,2024

Unexpected link found between 2 schizophrenia risk proteins

by Emily Caldwell,The Ohio State UniversityBehavioral alterations in MAP6−/−and Kv3.1−/−mice. Adult (3–6 months old) WT B6 (black bars), MAP6−/−(red bars), and Kv3.1−/−(g

Updated on: January 12,2024

Unexpected link found between 2 schizophrenia risk proteins

by Emily Caldwell,The Ohio State UniversityBehavioral alterations in MAP6−/−and Kv3.1−/−mice. Adult (3–6 months old) WT B6 (black bars), MAP6−/−(red bars), and Kv3.1−/−(g

Updated on:January 12,2024

Aging reduces the ability of regulatory T cells to enhance myelin regeneration, study finds

byMiguel Hernandez University of ElcheA Diagram explaining the experimental design of in vivo Treg depletion, Treg adoptive transfer and spinal cord demyelination. Representative images of immun

Updated on: March 28,2024

Aging reduces the ability of regulatory T cells to enhance myelin regeneration, study finds

byMiguel Hernandez University of ElcheA Diagram explaining the experimental design of in vivo Treg depletion, Treg adoptive transfer and spinal cord demyelination. Representative images of immun

Updated on:March 28,2024

IL-21 protein a key part of immune response to central nervous system infections

by Zachary Sweger,Pennsylvania State UniversityT cells infiltrating brains of MuPyV-infected mice captured in the Lukacher lab. Credit: Penn StateResearchers at Penn State College of Medicine no

Updated on: April 16,2024

IL-21 protein a key part of immune response to central nervous system infections

by Zachary Sweger,Pennsylvania State UniversityT cells infiltrating brains of MuPyV-infected mice captured in the Lukacher lab. Credit: Penn StateResearchers at Penn State College of Medicine no

Updated on:April 16,2024

Epigenetics blood markers can help understand dementia risk

byUniversity of ExeterOverview of the model generation. The model generation workflow consists of model training in the EXTEND and EMIF-AD cohorts using two different approaches. Credit:Al

Updated on: September 03,2024

Epigenetics blood markers can help understand dementia risk

byUniversity of ExeterOverview of the model generation. The model generation workflow consists of model training in the EXTEND and EMIF-AD cohorts using two different approaches. Credit:Al

Updated on:September 03,2024

How do we decide what to look at next? A computational model has the answer

byTechnical University of BerlinObject-based scanpath simulation in dynamic scenes. Credit: The image is derived from a frame of the field03 video of the VidCom dataset (Permission to Publish Co

Updated on: January 11,2024

How do we decide what to look at next? A computational model has the answer

byTechnical University of BerlinObject-based scanpath simulation in dynamic scenes. Credit: The image is derived from a frame of the field03 video of the VidCom dataset (Permission to Publish Co

Updated on:January 11,2024

Memory may be preserved in condition with brain changes similar to Alzheimer's disease

by American Academy of NeurologyCredit: Unsplash/CC0 Public DomainPrimary progressive aphasia is a rare neurodegenerative condition characterized by prominent language problems that worsen over t

Updated on: June 18,2024

Memory may be preserved in condition with brain changes similar to Alzheimer's disease

by American Academy of NeurologyCredit: Unsplash/CC0 Public DomainPrimary progressive aphasia is a rare neurodegenerative condition characterized by prominent language problems that worsen over t

Updated on:June 18,2024

Tau protein changes correlate with Alzheimer's disease dementia stage

by Alice McCarthy,Children's Hospital BostonPET scan of a human brain with Alzheimer's disease. Credit: public domainResearch into Alzheimer's disease has long focused on understandi

Updated on: April 02,2024

Tau protein changes correlate with Alzheimer's disease dementia stage

by Alice McCarthy,Children's Hospital BostonPET scan of a human brain with Alzheimer's disease. Credit: public domainResearch into Alzheimer's disease has long focused on understandi

Updated on:April 02,2024

Phase I clinical trial shows treatment designed to clear senescent cells in Alzheimer's disease is safe

by Atrium Health Wake Forest BaptistSenescent neurons are represented by areas of blue, red and white. Senescent cells are old, sick cells that cannot properly repair themselves and don't die

Updated on: March 02,2024

Phase I clinical trial shows treatment designed to clear senescent cells in Alzheimer's disease is safe

by Atrium Health Wake Forest BaptistSenescent neurons are represented by areas of blue, red and white. Senescent cells are old, sick cells that cannot properly repair themselves and don't die

Updated on:March 02,2024

Pandemic adds to challenge of caring for loved one with dementia

by Amy NortonBefore the COVID-19 outbreak, Annette Adams-Brown's 87-year-old mother was an avid follower of TV news. Now Adams-Brown has to channel-surf for a less stressful pastime.Her mother, Be

Updated on: May 13,2024

Pandemic adds to challenge of caring for loved one with dementia

by Amy NortonBefore the COVID-19 outbreak, Annette Adams-Brown's 87-year-old mother was an avid follower of TV news. Now Adams-Brown has to channel-surf for a less stressful pastime.Her mother, Be

Updated on:May 13,2024

How gut bacteria influence the effects of cocaine in mice

by Cell PressThis photo represents Cuesta et al.'s demonstration that cocaine exposure increases norepinephrine in the gut facilitating γ-Proteobacteria colonization. This gut microbiota shif

Updated on: February 03,2024

How gut bacteria influence the effects of cocaine in mice

by Cell PressThis photo represents Cuesta et al.'s demonstration that cocaine exposure increases norepinephrine in the gut facilitating γ-Proteobacteria colonization. This gut microbiota shif

Updated on:February 03,2024