New insights into the formation of toxic protein clumps in Alzheimer's disease

byForschungszentrum JuelichSmall Aβ oligomers (left: cryo-electron microscopy) are clumps consisting of just a few Aβ molecules. They cluster together to form short, worm-like structures known a

Updated on: April 18,2024

New insights into the formation of toxic protein clumps in Alzheimer's disease

byForschungszentrum JuelichSmall Aβ oligomers (left: cryo-electron microscopy) are clumps consisting of just a few Aβ molecules. They cluster together to form short, worm-like structures known a

Updated on:April 18,2024

'New' ALS gene destabilizes neuron's structure and chokes off its nucleus

byNorthwestern UniversityCredit: Pixabay/CC0 Public DomainThe viral ALS Ice Bucket Challenge a few years ago raised major funding that resulted in the discovery of new genes connected to the dis

Updated on: April 23,2024

'New' ALS gene destabilizes neuron's structure and chokes off its nucleus

byNorthwestern UniversityCredit: Pixabay/CC0 Public DomainThe viral ALS Ice Bucket Challenge a few years ago raised major funding that resulted in the discovery of new genes connected to the dis

Updated on:April 23,2024

Clinical trial suggests new drug candidate for spinocerebellar ataxia may offer certain therapeutic benefits

byNiigata UniversityL-arginine inhibits the aggregation of polyglutamine proteins in neuronal cells. Credit: Niigata UniversityA team has conducted a trial on the efficacy and safety of L-argini

Updated on: December 18,2024

Clinical trial suggests new drug candidate for spinocerebellar ataxia may offer certain therapeutic benefits

byNiigata UniversityL-arginine inhibits the aggregation of polyglutamine proteins in neuronal cells. Credit: Niigata UniversityA team has conducted a trial on the efficacy and safety of L-argini

Updated on:December 18,2024

Lab-grown human neuron assembloids effectively model synaptic plasticity

bySt. Jude Children's Research HospitalCredit:Cell Reports(2024). DOI: 10.1016/j.celrep.2024.114503The ability to study human neurological systems depends on having viable, accur

Updated on: July 31,2024

Lab-grown human neuron assembloids effectively model synaptic plasticity

bySt. Jude Children's Research HospitalCredit:Cell Reports(2024). DOI: 10.1016/j.celrep.2024.114503The ability to study human neurological systems depends on having viable, accur

Updated on:July 31,2024

Super-resolution microscopy sheds light on how dementia protein becomes dysfunctional

by University of QueenslandThe signalling protein Fyn moving and forming clusters in living brain cells - viewed using super-resolution microscopy. Credit: Meunier Lab, University of QueenslandUn

Updated on: May 05,2024

Super-resolution microscopy sheds light on how dementia protein becomes dysfunctional

by University of QueenslandThe signalling protein Fyn moving and forming clusters in living brain cells - viewed using super-resolution microscopy. Credit: Meunier Lab, University of QueenslandUn

Updated on:May 05,2024

Genomics- and image-guided subtyping refines characterization of Alzheimer's disease

by Society of Nuclear Medicine and Molecular ImagingRight and left hemisphere brain surface plots showing the strength of the canonical vector, νƙ, for each subtype. Credit: Images created by Fan Yang

Updated on: June 14,2024

Genomics- and image-guided subtyping refines characterization of Alzheimer's disease

by Society of Nuclear Medicine and Molecular ImagingRight and left hemisphere brain surface plots showing the strength of the canonical vector, νƙ, for each subtype. Credit: Images created by Fan Yang

Updated on:June 14,2024

Alzheimer's disease risk gene APOE4 impairs function of brain immune cells

by University of Eastern FinlandThe induced pluripotent stem cell (iPSC) -derived microglia demonstrate that apolipoprotein E4 (APOE4) has a profound impact on several functions of human brain im

Updated on: April 08,2024

Alzheimer's disease risk gene APOE4 impairs function of brain immune cells

by University of Eastern FinlandThe induced pluripotent stem cell (iPSC) -derived microglia demonstrate that apolipoprotein E4 (APOE4) has a profound impact on several functions of human brain im

Updated on:April 08,2024

Lightweight, head-mounted microscope unveils brain oxygenation in freely moving mice

by TranSpreadPhotoacoustic fiberscope for cerebral imaging in the freely moving-state. Credit:Light: Science & Applications(2024). DOI: 10.1038/s41377-023-01348-3The brain consumes app

Updated on: April 06,2024

Lightweight, head-mounted microscope unveils brain oxygenation in freely moving mice

by TranSpreadPhotoacoustic fiberscope for cerebral imaging in the freely moving-state. Credit:Light: Science & Applications(2024). DOI: 10.1038/s41377-023-01348-3The brain consumes app

Updated on:April 06,2024

Improving quality of life and sleep in people with memory problems without using drugs

by University of Pennsylvania School of NursingCredit: Pixabay/CC0 Public DomainA study from the University of Pennsylvania School of Nursing (Penn Nursing), recentlypublishedin

Updated on: March 05,2024

Improving quality of life and sleep in people with memory problems without using drugs

by University of Pennsylvania School of NursingCredit: Pixabay/CC0 Public DomainA study from the University of Pennsylvania School of Nursing (Penn Nursing), recentlypublishedin

Updated on:March 05,2024

Our brains take rhythmic snapshots of the world as we walk

by Matthew Davidson,The ConversationCredit: Pixabay/CC0 Public DomainFor decades, psychology departments around the world have studied human behavior in darkened laboratories that restrict natur

Updated on: March 19,2024

Our brains take rhythmic snapshots of the world as we walk

by Matthew Davidson,The ConversationCredit: Pixabay/CC0 Public DomainFor decades, psychology departments around the world have studied human behavior in darkened laboratories that restrict natur

Updated on:March 19,2024

Decoding the genetics that drive disease

by University of South AustraliaSome human genes traditionally labeled as 'bad' are not always what they seem. Credit: Gerd Altmann from PixabayFrom Alzheimer's to obesity, life can c

Updated on: July 01,2024

Decoding the genetics that drive disease

by University of South AustraliaSome human genes traditionally labeled as 'bad' are not always what they seem. Credit: Gerd Altmann from PixabayFrom Alzheimer's to obesity, life can c

Updated on:July 01,2024

How gut neurons communicate with the brain to control thirst

by Lori Dajose,California Institute of TechnologyFig. 1: The vagus nerve responds to visceral osmolality changes. Credit: DOI: 10.1038/s41586-021-04359-5Drinking a glass of water is often suffic

Updated on: February 05,2024

How gut neurons communicate with the brain to control thirst

by Lori Dajose,California Institute of TechnologyFig. 1: The vagus nerve responds to visceral osmolality changes. Credit: DOI: 10.1038/s41586-021-04359-5Drinking a glass of water is often suffic

Updated on:February 05,2024