New Alzheimer's disease pathways identified

by University of LübeckPath model of main findings. This path model summarizes the main-effect mediation model. Circles indicate principal components or latent variables, rectangles represent observed

Updated on: March 02,2024

New Alzheimer's disease pathways identified

by University of LübeckPath model of main findings. This path model summarizes the main-effect mediation model. Circles indicate principal components or latent variables, rectangles represent observed

Updated on:March 02,2024

Protein experts show altered ubiquitin signaling induces hallmarks of sporadic Alzheimer's disease

by Technion - Israel Institute of TechnologyUBB+1accumulates in the early stages of AD postmortem tissue.aImmunofluorescence staining of human tissue (ER = hippocampal complex,

Updated on: March 02,2024

Protein experts show altered ubiquitin signaling induces hallmarks of sporadic Alzheimer's disease

by Technion - Israel Institute of TechnologyUBB+1accumulates in the early stages of AD postmortem tissue.aImmunofluorescence staining of human tissue (ER = hippocampal complex,

Updated on:March 02,2024

Recurrent brain trauma may increase Alzheimer's risk

by Radiological Society of North AmericaParametric maps of amyloid deposition in healthy control participants (A and B) and blast-exposed military instructors (C and D) at baseline (A and C) and

Updated on: June 01,2024

Recurrent brain trauma may increase Alzheimer's risk

by Radiological Society of North AmericaParametric maps of amyloid deposition in healthy control participants (A and B) and blast-exposed military instructors (C and D) at baseline (A and C) and

Updated on:June 01,2024

Care more expensive for dementia patients and families in last years of life

by The Mount Sinai HospitalThe cost of care over the last five years of life for patients with dementia is significantly higher than for patients who die from heart disease, cancer, or other caus

Updated on: February 26,2024

Care more expensive for dementia patients and families in last years of life

by The Mount Sinai HospitalThe cost of care over the last five years of life for patients with dementia is significantly higher than for patients who die from heart disease, cancer, or other caus

Updated on:February 26,2024

Dementia risk scores have high error rates

by Lori SolomonCurrent dementia risk scores have high error rates and limited clinical utility for estimating 10-year risk, according to a study published online June 13 inJAMA Network Open.Mika

Updated on: May 06,2024

Dementia risk scores have high error rates

by Lori SolomonCurrent dementia risk scores have high error rates and limited clinical utility for estimating 10-year risk, according to a study published online June 13 inJAMA Network Open.Mika

Updated on:May 06,2024

Epigenetics blood markers can help understand dementia risk

byUniversity of ExeterOverview of the model generation. The model generation workflow consists of model training in the EXTEND and EMIF-AD cohorts using two different approaches. Credit:Al

Updated on: September 03,2024

Epigenetics blood markers can help understand dementia risk

byUniversity of ExeterOverview of the model generation. The model generation workflow consists of model training in the EXTEND and EMIF-AD cohorts using two different approaches. Credit:Al

Updated on:September 03,2024

Link found between chronic inflammation and risk for Alzheimer's disease

by Boston University School of MedicineWhile it is widely shown that possessing the ApoE4 gene is the major genetic risk factor of Alzheimer's disease (AD), not all ApoE4 carriers develop AD.

Updated on: March 07,2024

Link found between chronic inflammation and risk for Alzheimer's disease

by Boston University School of MedicineWhile it is widely shown that possessing the ApoE4 gene is the major genetic risk factor of Alzheimer's disease (AD), not all ApoE4 carriers develop AD.

Updated on:March 07,2024

Genetic 'hotspots' that speed up and slow down brain aging could provide new targets for Alzheimer's drugs

by University of Southern CaliforniaCredit: CC0 Public DomainResearchers from a USC-led consortium have discovered 15 "hotspots" in the genome that either speed up brain aging or slow i

Updated on: June 20,2024

Genetic 'hotspots' that speed up and slow down brain aging could provide new targets for Alzheimer's drugs

by University of Southern CaliforniaCredit: CC0 Public DomainResearchers from a USC-led consortium have discovered 15 "hotspots" in the genome that either speed up brain aging or slow i

Updated on:June 20,2024

The brain pulsates differently in people suffering from Alzheimer's disease

by University of OuluIn the magnetic resonance image, a healthy brain is higher and a lower one with Alzheimer's disease. Pulsations in the brain appear as red signals at the frequency of the hear

Updated on: April 20,2024

The brain pulsates differently in people suffering from Alzheimer's disease

by University of OuluIn the magnetic resonance image, a healthy brain is higher and a lower one with Alzheimer's disease. Pulsations in the brain appear as red signals at the frequency of the hear

Updated on:April 20,2024

Thorough and ongoing neurological assessments crucial to care of patients with altered level of consciousness

by American Association of Critical-Care Nurses (AACN)Credit: Unsplash/CC0 Public DomainPatients with altered level of consciousness are among the most difficult to assess and may have subtle neurolog

Updated on: February 03,2024

Thorough and ongoing neurological assessments crucial to care of patients with altered level of consciousness

by American Association of Critical-Care Nurses (AACN)Credit: Unsplash/CC0 Public DomainPatients with altered level of consciousness are among the most difficult to assess and may have subtle neurolog

Updated on:February 03,2024

Lightweight, head-mounted microscope unveils brain oxygenation in freely moving mice

by TranSpreadPhotoacoustic fiberscope for cerebral imaging in the freely moving-state. Credit:Light: Science & Applications(2024). DOI: 10.1038/s41377-023-01348-3The brain consumes app

Updated on: April 06,2024

Lightweight, head-mounted microscope unveils brain oxygenation in freely moving mice

by TranSpreadPhotoacoustic fiberscope for cerebral imaging in the freely moving-state. Credit:Light: Science & Applications(2024). DOI: 10.1038/s41377-023-01348-3The brain consumes app

Updated on:April 06,2024

Metabolism linked to brain health

by University of South AustraliaCredit: MART PRODUCTION from PexelsEvery three seconds, someone in the world is diagnosed with dementia. And while there is no known cure, changes in the brain can

Updated on: April 01,2024

Metabolism linked to brain health

by University of South AustraliaCredit: MART PRODUCTION from PexelsEvery three seconds, someone in the world is diagnosed with dementia. And while there is no known cure, changes in the brain can

Updated on:April 01,2024