Protein experts show altered ubiquitin signaling induces hallmarks of sporadic Alzheimer's disease

by Technion - Israel Institute of TechnologyUBB+1accumulates in the early stages of AD postmortem tissue.aImmunofluorescence staining of human tissue (ER = hippocampal complex,

Updated on: March 02,2024

Protein experts show altered ubiquitin signaling induces hallmarks of sporadic Alzheimer's disease

by Technion - Israel Institute of TechnologyUBB+1accumulates in the early stages of AD postmortem tissue.aImmunofluorescence staining of human tissue (ER = hippocampal complex,

Updated on:March 02,2024

Alzheimer's protein is likely held together with many weak chemical interactions

by University of TokyoCredit: CC0 Public DomainThe chemical interactions that give proteins their shape may be weaker and more numerous than previously recognized. These weak connections provide

Updated on: April 18,2024

Alzheimer's protein is likely held together with many weak chemical interactions

by University of TokyoCredit: CC0 Public DomainThe chemical interactions that give proteins their shape may be weaker and more numerous than previously recognized. These weak connections provide

Updated on:April 18,2024

A new approach to treating amyotrophic lateral sclerosis and frontotemporal dementia

by Academia SinicaSchematic representation of mechanisms involved in poly-GR/-PR-induced neuronal degradation and the potential therapeutic action of the sulfated disaccharide SOS. Credit: Academia Si

Updated on: March 28,2024

A new approach to treating amyotrophic lateral sclerosis and frontotemporal dementia

by Academia SinicaSchematic representation of mechanisms involved in poly-GR/-PR-induced neuronal degradation and the potential therapeutic action of the sulfated disaccharide SOS. Credit: Academia Si

Updated on:March 28,2024

Link found between chronic inflammation and risk for Alzheimer's disease

by Boston University School of MedicineWhile it is widely shown that possessing the ApoE4 gene is the major genetic risk factor of Alzheimer's disease (AD), not all ApoE4 carriers develop AD.

Updated on: March 07,2024

Link found between chronic inflammation and risk for Alzheimer's disease

by Boston University School of MedicineWhile it is widely shown that possessing the ApoE4 gene is the major genetic risk factor of Alzheimer's disease (AD), not all ApoE4 carriers develop AD.

Updated on:March 07,2024

Genetic 'hotspots' that speed up and slow down brain aging could provide new targets for Alzheimer's drugs

by University of Southern CaliforniaCredit: CC0 Public DomainResearchers from a USC-led consortium have discovered 15 "hotspots" in the genome that either speed up brain aging or slow i

Updated on: June 20,2024

Genetic 'hotspots' that speed up and slow down brain aging could provide new targets for Alzheimer's drugs

by University of Southern CaliforniaCredit: CC0 Public DomainResearchers from a USC-led consortium have discovered 15 "hotspots" in the genome that either speed up brain aging or slow i

Updated on:June 20,2024

Unusual mechanism in rare mutation associated with Alzheimer's uncovered

by University of Chicago Medical CenterPET scan of a human brain with Alzheimer's disease. Credit: public domainA novel mechanism has been identified that might explain why a rare mutation is

Updated on: June 01,2024

Unusual mechanism in rare mutation associated with Alzheimer's uncovered

by University of Chicago Medical CenterPET scan of a human brain with Alzheimer's disease. Credit: public domainA novel mechanism has been identified that might explain why a rare mutation is

Updated on:June 01,2024

New clues to early development of schizophrenia

byElsevierDerivation and characterization of hCSs. (A) Experimental design of the study. (B) Main growth factors and media used for neural induction and differentiation. DM and SB are SMAD inhib

Updated on: January 12,2024

New clues to early development of schizophrenia

byElsevierDerivation and characterization of hCSs. (A) Experimental design of the study. (B) Main growth factors and media used for neural induction and differentiation. DM and SB are SMAD inhib

Updated on:January 12,2024

Brain's 'appetite control center' found to be different in people who are overweight or living with obesity

by University of CambridgeCredit: CC0 Public DomainCambridge scientists have shown that the hypothalamus, a key region of the brain involved in controlling appetite, is different in the brains of

Updated on: February 05,2024

Brain's 'appetite control center' found to be different in people who are overweight or living with obesity

by University of CambridgeCredit: CC0 Public DomainCambridge scientists have shown that the hypothalamus, a key region of the brain involved in controlling appetite, is different in the brains of

Updated on:February 05,2024

New Alzheimer trial to use epilepsy drug that calms brain activity

by Scott Dance, The Baltimore SunWhat could be one of the first treatments to delay or prevent Alzheimer's disease received a big boost from the National Institute on Aging, which is putting up $7

Updated on: February 26,2024

New Alzheimer trial to use epilepsy drug that calms brain activity

by Scott Dance, The Baltimore SunWhat could be one of the first treatments to delay or prevent Alzheimer's disease received a big boost from the National Institute on Aging, which is putting up $7

Updated on:February 26,2024

New biomarker for dementia diagnosis

by Flinders UniversityProfessor Arduino Mangoni, Head of Clinical Pharmacology at Flinders University, in his research laboratory in South Australia. Credit: Flinders UniversityMedical researcher

Updated on: May 11,2024

New biomarker for dementia diagnosis

by Flinders UniversityProfessor Arduino Mangoni, Head of Clinical Pharmacology at Flinders University, in his research laboratory in South Australia. Credit: Flinders UniversityMedical researcher

Updated on:May 11,2024

Chatbots for dementia patients and caregivers need more work

by Holly Ober,University of California - RiversideCredit: CC0 Public DomainChatbots hold promise for dementia patient or caregiver support, but are still in their infancy, finds a paper publishe

Updated on: May 08,2024

Chatbots for dementia patients and caregivers need more work

by Holly Ober,University of California - RiversideCredit: CC0 Public DomainChatbots hold promise for dementia patient or caregiver support, but are still in their infancy, finds a paper publishe

Updated on:May 08,2024

COVID-19 pneumonia increases dementia risk

by University of MissouriUniversity of Missouri Health Care COVID-19 progressive care unit. Credit: Justin Kelley/MU Health CareA new study from the from the University of Missouri School of Medi

Updated on: March 26,2024

COVID-19 pneumonia increases dementia risk

by University of MissouriUniversity of Missouri Health Care COVID-19 progressive care unit. Credit: Justin Kelley/MU Health CareA new study from the from the University of Missouri School of Medi

Updated on:March 26,2024