Understanding the genetic roots of rare mutations in Alzheimer's disease

byVIB (the Flanders Institute for Biotechnology)Hippocampal neurons with staining for endosomes (turquoise and purple) and lysosomes (yellow). When the PSEN2 gene is absent or carries a familial

Updated on: December 11,2024

Understanding the genetic roots of rare mutations in Alzheimer's disease

byVIB (the Flanders Institute for Biotechnology)Hippocampal neurons with staining for endosomes (turquoise and purple) and lysosomes (yellow). When the PSEN2 gene is absent or carries a familial

Updated on:December 11,2024

How aggression-promoting brain peptide works in fruit flies

by Salk InstituteA fruit fly brain showing male-specific tachykininergic neurons (magenta), which make the neuropeptide tachykinin, and neurons that express TkR86C (green), which receive tachykin

Updated on: February 18,2024

How aggression-promoting brain peptide works in fruit flies

by Salk InstituteA fruit fly brain showing male-specific tachykininergic neurons (magenta), which make the neuropeptide tachykinin, and neurons that express TkR86C (green), which receive tachykin

Updated on:February 18,2024

Alzheimer's disease: Sex affects tau accumulation in the brain

by Society of Nuclear Medicine and Molecular ImagingSex Modulates the ApoE ε4 Effect on 18F-AV-1451 Tau PET. Credit: Paranjpe M, Liu M, Paranjpe I, et al.The strongest genetic risk factor for Alzheime

Updated on: April 10,2024

Alzheimer's disease: Sex affects tau accumulation in the brain

by Society of Nuclear Medicine and Molecular ImagingSex Modulates the ApoE ε4 Effect on 18F-AV-1451 Tau PET. Credit: Paranjpe M, Liu M, Paranjpe I, et al.The strongest genetic risk factor for Alzheime

Updated on:April 10,2024

Study indicates possible link between chronic stress and Alzheimer's disease

by Karolinska InstitutetCredit: Unsplash/CC0 Public DomainResearchers from Karolinska Institutet have publisheda studyinAlzheimer's Research & Therapythat addresse

Updated on: March 02,2024

Study indicates possible link between chronic stress and Alzheimer's disease

by Karolinska InstitutetCredit: Unsplash/CC0 Public DomainResearchers from Karolinska Institutet have publisheda studyinAlzheimer's Research & Therapythat addresse

Updated on:March 02,2024

Early-life stress can disrupt maturation of brain's reward circuits, promoting disorders

by University of California, IrvineA projection of CRH/GABA neurons in the medial BLA to the medial NAc shell.a–cRetrograde tracing of CRH+neuronal inputs to medial NAc shell of

Updated on: March 26,2024

Early-life stress can disrupt maturation of brain's reward circuits, promoting disorders

by University of California, IrvineA projection of CRH/GABA neurons in the medial BLA to the medial NAc shell.a–cRetrograde tracing of CRH+neuronal inputs to medial NAc shell of

Updated on:March 26,2024

New proteins involved in spinocerebellar ataxia provide insight into selective neuronal vulnerability

by Molly Chiu,Baylor College of MedicineGraphical abstract. Credit:Neuron(2022). DOI: 10.1016/j.neuron.2022.11.016Neurodegenerative disorders like Alzheimer's and Parkinson's

Updated on: February 05,2024

New proteins involved in spinocerebellar ataxia provide insight into selective neuronal vulnerability

by Molly Chiu,Baylor College of MedicineGraphical abstract. Credit:Neuron(2022). DOI: 10.1016/j.neuron.2022.11.016Neurodegenerative disorders like Alzheimer's and Parkinson's

Updated on:February 05,2024

Injuries to primary visual cortex cause long-term dysfunction of neural circuits

by Marcin Powęska,Polish Academy of SciencesInjuries to primary visual cortex cause long-term dysfunction of neural circuits. Credit: ICTER / Grzegorz KrzyzewskiEven mild head injuries can mean

Updated on: February 05,2024

Injuries to primary visual cortex cause long-term dysfunction of neural circuits

by Marcin Powęska,Polish Academy of SciencesInjuries to primary visual cortex cause long-term dysfunction of neural circuits. Credit: ICTER / Grzegorz KrzyzewskiEven mild head injuries can mean

Updated on:February 05,2024

Microscopic blood vessel disease in the brain's white matter associated with worse cognition in Alzheimer's

by Medical College of Georgia at Augusta UniversityDr. Zsolt Bagi with coauthors Katie Anne Fopiano, AU graduate student, and Dr. Yanna Tian, who just earned her graduate degree from AU and has s

Updated on: April 20,2024

Microscopic blood vessel disease in the brain's white matter associated with worse cognition in Alzheimer's

by Medical College of Georgia at Augusta UniversityDr. Zsolt Bagi with coauthors Katie Anne Fopiano, AU graduate student, and Dr. Yanna Tian, who just earned her graduate degree from AU and has s

Updated on:April 20,2024

Connections between addictive drugs and brain function in mice

by John Spizzirri,Argonne National LaboratoryFigure 1. Experimental design for dopamine connectomics. (A) Adeno-associated viruses (AAVs) expressing Cre-dependent Apex2 were bilaterally injected

Updated on: February 05,2024

Connections between addictive drugs and brain function in mice

by John Spizzirri,Argonne National LaboratoryFigure 1. Experimental design for dopamine connectomics. (A) Adeno-associated viruses (AAVs) expressing Cre-dependent Apex2 were bilaterally injected

Updated on:February 05,2024

Brain stimulation improves motor skill learning at older age

by Ecole Polytechnique Federale de LausanneA visual summary of the study. Credit: Pablo Maceira-Elvira (EPFL)Even though we don't think about it, every movement we make in our daily life esse

Updated on: February 21,2024

Brain stimulation improves motor skill learning at older age

by Ecole Polytechnique Federale de LausanneA visual summary of the study. Credit: Pablo Maceira-Elvira (EPFL)Even though we don't think about it, every movement we make in our daily life esse

Updated on:February 21,2024

Molecular alterations in neuronal trophic regulation in Alzheimer's pathology

by Jason Clement,McGill UniversityCredit: Unsplash/CC0 Public DomainFor decades researchers have known that Alzheimer's disease (AD) causes the atrophy of a system of neurons and synapses hi

Updated on: April 02,2024

Molecular alterations in neuronal trophic regulation in Alzheimer's pathology

by Jason Clement,McGill UniversityCredit: Unsplash/CC0 Public DomainFor decades researchers have known that Alzheimer's disease (AD) causes the atrophy of a system of neurons and synapses hi

Updated on:April 02,2024

New research explains how brain blood vessels are formed

by Université libre de BruxellesMmp25 as a regulator of brain-specific angiogenesis.a, The TC genotype in mosaic sprouts during brain vascular invasion (36 hpf,n = 23 sprouts) and tru

Updated on: April 06,2024

New research explains how brain blood vessels are formed

by Université libre de BruxellesMmp25 as a regulator of brain-specific angiogenesis.a, The TC genotype in mosaic sprouts during brain vascular invasion (36 hpf,n = 23 sprouts) and tru

Updated on:April 06,2024