Skin cells from frontotemporal dementia patients may reveal disease mechanisms and biomarkers for drug research

by University of Eastern FinlandFibroblasts of C9-HRE carriers show unaltered C9orf72 levels, express RNA foci, but do not display DPR proteins. a TaqMan assay from fibroblast RNA for C9orf72 all

Updated on: May 28,2024 3

Skin cells from frontotemporal dementia patients may reveal disease mechanisms and biomarkers for drug research

by University of Eastern FinlandFibroblasts of C9-HRE carriers show unaltered C9orf72 levels, express RNA foci, but do not display DPR proteins. a TaqMan assay from fibroblast RNA for C9orf72 all

Updated on:May 28,2024 3

Largest-ever genetic study of epilepsy finds possible therapeutic targets

by Ari Navetta,Broad Institute of MIT and HarvardEpilepsy genetic architecture from large-scale genetic association studies. Credit:Nature Neuroscience(2024). DOI: 10.1038/s41593-024

Updated on: October 09,2024 0

Largest-ever genetic study of epilepsy finds possible therapeutic targets

by Ari Navetta,Broad Institute of MIT and HarvardEpilepsy genetic architecture from large-scale genetic association studies. Credit:Nature Neuroscience(2024). DOI: 10.1038/s41593-024

Updated on:October 09,2024 0

Oxytocin: The love hormone that holds the key to better memory

byTokyo University of ScienceResearchers discovered that activating a specific group of oxytocin neurons in the mouse brain improves performance in novel object recognition tasks. Credit: Akiyos

Updated on: March 13,2024 6

Oxytocin: The love hormone that holds the key to better memory

byTokyo University of ScienceResearchers discovered that activating a specific group of oxytocin neurons in the mouse brain improves performance in novel object recognition tasks. Credit: Akiyos

Updated on:March 13,2024 6

Single-cell dissection of Alzheimer's vascular changes across six brain regions

by Rachel Gordon, MIT Computer Science & Artificial Intelligence LabExperimental validation of adDEGs. a. Chromogenic RNAscope for ABCC9 and SLC6A1. Prefrontal cortex brain sections (n = 4 for AD

Updated on: April 20,2024 20

Single-cell dissection of Alzheimer's vascular changes across six brain regions

by Rachel Gordon, MIT Computer Science & Artificial Intelligence LabExperimental validation of adDEGs. a. Chromogenic RNAscope for ABCC9 and SLC6A1. Prefrontal cortex brain sections (n = 4 for AD

Updated on:April 20,2024 20

Study shows glucose levels affect cognitive performance in people with type 1 diabetes differently

byMcLean HospitalCredit: Wikimedia CommonsA new study led by researchers at McLean Hospital (a member of Mass General Brigham) and Washington State University used advances in digital testing to

Updated on: March 28,2024 0

Study shows glucose levels affect cognitive performance in people with type 1 diabetes differently

byMcLean HospitalCredit: Wikimedia CommonsA new study led by researchers at McLean Hospital (a member of Mass General Brigham) and Washington State University used advances in digital testing to

Updated on:March 28,2024 0

Consistent gene changes in Alzheimer's disease across studies

by Society for NeuroscienceTop 20 up and down-regulated genes for late phase Alzheimer's disease. Credit: Zhuang et al.,eNeuro2019A comparison of mouse Alzheimer's disease mod

Updated on: April 16,2024 10

Consistent gene changes in Alzheimer's disease across studies

by Society for NeuroscienceTop 20 up and down-regulated genes for late phase Alzheimer's disease. Credit: Zhuang et al.,eNeuro2019A comparison of mouse Alzheimer's disease mod

Updated on:April 16,2024 10

Alzheimer's brain barrier damage theory could pave way for new treatments

by University of ReadingCredit: Pixabay/CC0 Public DomainAlzheimer's Disease could be caused by damage to a protective barrier in the body that allows fatty substances to build up in the brai

Updated on: April 07,2024 12

Alzheimer's brain barrier damage theory could pave way for new treatments

by University of ReadingCredit: Pixabay/CC0 Public DomainAlzheimer's Disease could be caused by damage to a protective barrier in the body that allows fatty substances to build up in the brai

Updated on:April 07,2024 12

Neuroscientists discover interactions between brain waves and nerve cells during human memory processes

by University Hospital of BonnIllustration of the hypothesis that human associative object–location memory is linked to the coactivity of object cells and place cells during hippocampal ripples. We pr

Updated on: March 13,2024 8

Neuroscientists discover interactions between brain waves and nerve cells during human memory processes

by University Hospital of BonnIllustration of the hypothesis that human associative object–location memory is linked to the coactivity of object cells and place cells during hippocampal ripples. We pr

Updated on:March 13,2024 8

Partially sighted may be at higher risk of dementia

by Anglia Ruskin UniversityCredit: CC0 Public DomainOlder people with vision loss are significantly more likely to suffer mild cognitive impairment, which can be a precursor to dementia, accordin

Updated on: May 05,2024 12

Partially sighted may be at higher risk of dementia

by Anglia Ruskin UniversityCredit: CC0 Public DomainOlder people with vision loss are significantly more likely to suffer mild cognitive impairment, which can be a precursor to dementia, accordin

Updated on:May 05,2024 12

Brain imaging of tau protein in patients with various forms of dementia

by Cell PressThis figure shows associations between the Clinical Disease Severity and the Extent of Areas Showing Increased 18F-PM-PBB3 Binding in the AD Spectrum. Credit: Tagai, Ono, and Kubota

Updated on: May 05,2024 18

Brain imaging of tau protein in patients with various forms of dementia

by Cell PressThis figure shows associations between the Clinical Disease Severity and the Extent of Areas Showing Increased 18F-PM-PBB3 Binding in the AD Spectrum. Credit: Tagai, Ono, and Kubota

Updated on:May 05,2024 18

'New' ALS gene destabilizes neuron's structure and chokes off its nucleus

byNorthwestern UniversityCredit: Pixabay/CC0 Public DomainThe viral ALS Ice Bucket Challenge a few years ago raised major funding that resulted in the discovery of new genes connected to the dis

Updated on: April 23,2024 0

'New' ALS gene destabilizes neuron's structure and chokes off its nucleus

byNorthwestern UniversityCredit: Pixabay/CC0 Public DomainThe viral ALS Ice Bucket Challenge a few years ago raised major funding that resulted in the discovery of new genes connected to the dis

Updated on:April 23,2024 0

Household and family ties significant in staving off dementia

by University of AdelaideCredit: Unsplash/CC0 Public DomainIn a global study, researchers in evolutionary medicine at the University of Adelaide have found that people living in larger households

Updated on: June 20,2024 8

Household and family ties significant in staving off dementia

by University of AdelaideCredit: Unsplash/CC0 Public DomainIn a global study, researchers in evolutionary medicine at the University of Adelaide have found that people living in larger households

Updated on:June 20,2024 8