Protein experts show altered ubiquitin signaling induces hallmarks of sporadic Alzheimer's disease

by Technion - Israel Institute of TechnologyUBB+1accumulates in the early stages of AD postmortem tissue.aImmunofluorescence staining of human tissue (ER = hippocampal complex,

Updated on: March 02,2024

Protein experts show altered ubiquitin signaling induces hallmarks of sporadic Alzheimer's disease

by Technion - Israel Institute of TechnologyUBB+1accumulates in the early stages of AD postmortem tissue.aImmunofluorescence staining of human tissue (ER = hippocampal complex,

Updated on:March 02,2024

New clues to early development of schizophrenia

byElsevierDerivation and characterization of hCSs. (A) Experimental design of the study. (B) Main growth factors and media used for neural induction and differentiation. DM and SB are SMAD inhib

Updated on: January 12,2024

New clues to early development of schizophrenia

byElsevierDerivation and characterization of hCSs. (A) Experimental design of the study. (B) Main growth factors and media used for neural induction and differentiation. DM and SB are SMAD inhib

Updated on:January 12,2024

Gout strongly associated with reduced gray matter and increased neurodegenerative disease

by Justin Jackson , Medical XpressDifferences in regional gray matter volume between participants with gout (n = 1,165) and controls (n = 32,202), as analyzed by voxel-based morphometry. Blue regions

Updated on: May 13,2024

Gout strongly associated with reduced gray matter and increased neurodegenerative disease

by Justin Jackson , Medical XpressDifferences in regional gray matter volume between participants with gout (n = 1,165) and controls (n = 32,202), as analyzed by voxel-based morphometry. Blue regions

Updated on:May 13,2024

Can Mediterranean diet help people with MS preserve thinking skills?

by American Academy of NeurologyCredit: Pixabay/CC0 Public DomainPeople with multiple sclerosis (MS) who follow a Mediterranean diet may have a lower risk for problems with memory and thinking sk

Updated on: May 20,2024

Can Mediterranean diet help people with MS preserve thinking skills?

by American Academy of NeurologyCredit: Pixabay/CC0 Public DomainPeople with multiple sclerosis (MS) who follow a Mediterranean diet may have a lower risk for problems with memory and thinking sk

Updated on:May 20,2024

Discovery of cellular mechanism to maintain brain's energy could benefit late-life brain health

byUniversity College LondonDeletion of A2B receptors in hippocampal astrocytes. Credit:Nature(2024). DOI: 10.1038/s41586-024-07611-wA key mechanism which detects when the brain needs

Updated on: July 05,2024

Discovery of cellular mechanism to maintain brain's energy could benefit late-life brain health

byUniversity College LondonDeletion of A2B receptors in hippocampal astrocytes. Credit:Nature(2024). DOI: 10.1038/s41586-024-07611-wA key mechanism which detects when the brain needs

Updated on:July 05,2024

Epigenetics blood markers can help understand dementia risk

byUniversity of ExeterOverview of the model generation. The model generation workflow consists of model training in the EXTEND and EMIF-AD cohorts using two different approaches. Credit:Al

Updated on: September 03,2024

Epigenetics blood markers can help understand dementia risk

byUniversity of ExeterOverview of the model generation. The model generation workflow consists of model training in the EXTEND and EMIF-AD cohorts using two different approaches. Credit:Al

Updated on:September 03,2024

Lack of brain shrinkage may help predict who develops dementia with Lewy bodies

by Mayo ClinicDementia with Lewy bodies is a progressive disease that causes hallucinations, decline in mental abilities, rigid muscles, slow movement and tremors. With symptoms similar to Alzhei

Updated on: March 07,2024

Lack of brain shrinkage may help predict who develops dementia with Lewy bodies

by Mayo ClinicDementia with Lewy bodies is a progressive disease that causes hallucinations, decline in mental abilities, rigid muscles, slow movement and tremors. With symptoms similar to Alzhei

Updated on:March 07,2024

Case study showcases effectiveness of multimodality approaches for diagnosing hydrocephalus

by Beijing Institute of Technology Press Co., LtdThis case demonstrates the efficacy of using multimodality approaches for iNPH diagnosis, which saves the patient time and clinical costs, worthy of fu

Updated on: September 05,2024

Case study showcases effectiveness of multimodality approaches for diagnosing hydrocephalus

by Beijing Institute of Technology Press Co., LtdThis case demonstrates the efficacy of using multimodality approaches for iNPH diagnosis, which saves the patient time and clinical costs, worthy of fu

Updated on:September 05,2024

A&E attendance for people with dementia is common and increasing

by King's College LondonCredit: CC0 Public DomainA new paper published today in the journalAlzheimer's & Dementia: The Journal of the Alzheimer's Associationfound that

Updated on: May 09,2024

A&E attendance for people with dementia is common and increasing

by King's College LondonCredit: CC0 Public DomainA new paper published today in the journalAlzheimer's & Dementia: The Journal of the Alzheimer's Associationfound that

Updated on:May 09,2024

Oxytocin: The love hormone that holds the key to better memory

byTokyo University of ScienceResearchers discovered that activating a specific group of oxytocin neurons in the mouse brain improves performance in novel object recognition tasks. Credit: Akiyos

Updated on: March 13,2024

Oxytocin: The love hormone that holds the key to better memory

byTokyo University of ScienceResearchers discovered that activating a specific group of oxytocin neurons in the mouse brain improves performance in novel object recognition tasks. Credit: Akiyos

Updated on:March 13,2024

How a common food ingredient can take a wrong turn, leading to arthritis

by Mark Harden,CU Anschutz Medical CampusGraphical abstract. Credit:Journal of Clinical Investigation(2023). DOI: 10.1172/JCI167671A University of Colorado Department of Medicine fac

Updated on: March 19,2024

How a common food ingredient can take a wrong turn, leading to arthritis

by Mark Harden,CU Anschutz Medical CampusGraphical abstract. Credit:Journal of Clinical Investigation(2023). DOI: 10.1172/JCI167671A University of Colorado Department of Medicine fac

Updated on:March 19,2024

Alzheimer's beginnings prove to be a sticky situation

by Layne Cameron , Lisa Lapidus,Michigan State UniversityMSU's Lisa Lapidus uses lasers to reveal a common trait of Alzheimer's beginnings. Credit: G.L. KohuthLaser technology has reveal

Updated on: April 18,2024

Alzheimer's beginnings prove to be a sticky situation

by Layne Cameron , Lisa Lapidus,Michigan State UniversityMSU's Lisa Lapidus uses lasers to reveal a common trait of Alzheimer's beginnings. Credit: G.L. KohuthLaser technology has reveal

Updated on:April 18,2024