Protein experts show altered ubiquitin signaling induces hallmarks of sporadic Alzheimer's disease

by Technion - Israel Institute of TechnologyUBB+1accumulates in the early stages of AD postmortem tissue.aImmunofluorescence staining of human tissue (ER = hippocampal complex,

Updated on: March 02,2024

Protein experts show altered ubiquitin signaling induces hallmarks of sporadic Alzheimer's disease

by Technion - Israel Institute of TechnologyUBB+1accumulates in the early stages of AD postmortem tissue.aImmunofluorescence staining of human tissue (ER = hippocampal complex,

Updated on:March 02,2024

Discovery of cilia defects in ALS patients suggests new treatment path

byVIB (the Flanders Institute for Biotechnology)Motor neurons with damaged primary cilia (green) from patients with the C21orf2 mutation. Credit: VIBAmyotrophic lateral sclerosis (ALS) is a deva

Updated on: January 15,2025

Discovery of cilia defects in ALS patients suggests new treatment path

byVIB (the Flanders Institute for Biotechnology)Motor neurons with damaged primary cilia (green) from patients with the C21orf2 mutation. Credit: VIBAmyotrophic lateral sclerosis (ALS) is a deva

Updated on:January 15,2025

Expert offers perspective on experimental Alzheimer's disease drug

by Deb BalzerCredit: Pixabay/CC0 Public DomainAccording to drugmakers Eisai and Biogen, a Phase 3 clinical study on a potential new Alzheimer's disease drug shows promise. The study findings show

Updated on: April 18,2024

Expert offers perspective on experimental Alzheimer's disease drug

by Deb BalzerCredit: Pixabay/CC0 Public DomainAccording to drugmakers Eisai and Biogen, a Phase 3 clinical study on a potential new Alzheimer's disease drug shows promise. The study findings show

Updated on:April 18,2024

Team succeeds in determining the exact moment when the brain detects another person's gaze direction

byUniversity of GenevaExperimental paradigm and stimuli. Credit:NeuroImage(2024). DOI: 10.1016/j.neuroimage.2024.120659The gaze plays a central role in everyday social interactions.

Updated on: July 05,2024

Team succeeds in determining the exact moment when the brain detects another person's gaze direction

byUniversity of GenevaExperimental paradigm and stimuli. Credit:NeuroImage(2024). DOI: 10.1016/j.neuroimage.2024.120659The gaze plays a central role in everyday social interactions.

Updated on:July 05,2024

Dementia carers reassured they can – and should – call police about wandering patients

by University of PortsmouthCredit: CC0 Public DomainOnly a small proportion of cases of a person with dementia going missing are reported to police, according to a new study.Mostfamily care

Updated on: May 09,2024

Dementia carers reassured they can – and should – call police about wandering patients

by University of PortsmouthCredit: CC0 Public DomainOnly a small proportion of cases of a person with dementia going missing are reported to police, according to a new study.Mostfamily care

Updated on:May 09,2024

'Lack of cleaning' in brain cells is central to Alzheimer's disease

by University of CopenhagenCredit: CC0 Public DomainAn international research team with representation from the University of Copenhagen has created a better understanding of Alzheimer's. The

Updated on: May 18,2024

'Lack of cleaning' in brain cells is central to Alzheimer's disease

by University of CopenhagenCredit: CC0 Public DomainAn international research team with representation from the University of Copenhagen has created a better understanding of Alzheimer's. The

Updated on:May 18,2024

Research reveals link between spinal muscular atrophy and liver damage

byAgency for Science, Technology and Research (A*STAR), SingaporeGraphical abstract. Credit:Journal of Clinical Investigation(2024). DOI: 10.1172/JCI173702An international study has

Updated on: July 31,2024

Research reveals link between spinal muscular atrophy and liver damage

byAgency for Science, Technology and Research (A*STAR), SingaporeGraphical abstract. Credit:Journal of Clinical Investigation(2024). DOI: 10.1172/JCI173702An international study has

Updated on:July 31,2024

Odor biomarker for Alzheimer's disease

by Monell Chemical Senses CenterDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.A new study from the Monell Center, the U.S. Department of Agricultu

Updated on: February 27,2024

Odor biomarker for Alzheimer's disease

by Monell Chemical Senses CenterDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.A new study from the Monell Center, the U.S. Department of Agricultu

Updated on:February 27,2024

Converting brain immune cells into neurons helps mice recover after stroke

by Kyushu UniversityProduction of NeuroD1 in microglial cells induces their development into neurons, therefore decreasing the area of the brain with neuron loss. In scans of the mice brains, neurons

Updated on: January 12,2024

Converting brain immune cells into neurons helps mice recover after stroke

by Kyushu UniversityProduction of NeuroD1 in microglial cells induces their development into neurons, therefore decreasing the area of the brain with neuron loss. In scans of the mice brains, neurons

Updated on:January 12,2024

Alzheimer's protein is likely held together with many weak chemical interactions

by University of TokyoCredit: CC0 Public DomainThe chemical interactions that give proteins their shape may be weaker and more numerous than previously recognized. These weak connections provide

Updated on: April 18,2024

Alzheimer's protein is likely held together with many weak chemical interactions

by University of TokyoCredit: CC0 Public DomainThe chemical interactions that give proteins their shape may be weaker and more numerous than previously recognized. These weak connections provide

Updated on:April 18,2024

Time until dementia symptoms appear can be estimated via brain scan

by Tamara Bhandari,Washington University School of MedicineCredit: Pixabay/CC0 Public DomainResearchers at Washington University School of Medicine in St. Louis have developed an approach to est

Updated on: May 11,2024

Time until dementia symptoms appear can be estimated via brain scan

by Tamara Bhandari,Washington University School of MedicineCredit: Pixabay/CC0 Public DomainResearchers at Washington University School of Medicine in St. Louis have developed an approach to est

Updated on:May 11,2024

Promising Alzheimer's drug candidate prevents buildup of tau proteins in lab and fruit fly studies

byLancaster UniversityThe brain of a 7-day-old fruit fly with Tau expressed in a neuronal circuit used by the fly in olfactory memory. The green outlines the neurons, which are starting to swell

Updated on: October 21,2024

Promising Alzheimer's drug candidate prevents buildup of tau proteins in lab and fruit fly studies

byLancaster UniversityThe brain of a 7-day-old fruit fly with Tau expressed in a neuronal circuit used by the fly in olfactory memory. The green outlines the neurons, which are starting to swell

Updated on:October 21,2024