Energy storehouses in the brain may be source of Alzheimer's, targets of new therapy

by Arizona State UniversityDiego Mastroeni is a researcher in the ASU-Banner Neurodegenerative Disease Research Center. Credit: Biodesign Institute at Arizona State UniversityAlzheimer's dise

Updated on: May 18,2024

Energy storehouses in the brain may be source of Alzheimer's, targets of new therapy

by Arizona State UniversityDiego Mastroeni is a researcher in the ASU-Banner Neurodegenerative Disease Research Center. Credit: Biodesign Institute at Arizona State UniversityAlzheimer's dise

Updated on:May 18,2024

New Alzheimer's disease pathways identified

by University of LübeckPath model of main findings. This path model summarizes the main-effect mediation model. Circles indicate principal components or latent variables, rectangles represent observed

Updated on: March 02,2024

New Alzheimer's disease pathways identified

by University of LübeckPath model of main findings. This path model summarizes the main-effect mediation model. Circles indicate principal components or latent variables, rectangles represent observed

Updated on:March 02,2024

Study reveals key role of TRIO gene in epileptic encephalopathies

byUniversity of MontrealDefective migration of MGE-derived cortical INs inTrio–/–embryos. Credit:Molecular Psychiatry(2024). DOI: 10.1038/s41380-024-02742-yWhat are the m

Updated on: October 09,2024

Study reveals key role of TRIO gene in epileptic encephalopathies

byUniversity of MontrealDefective migration of MGE-derived cortical INs inTrio–/–embryos. Credit:Molecular Psychiatry(2024). DOI: 10.1038/s41380-024-02742-yWhat are the m

Updated on:October 09,2024

Discovery of cellular mechanism to maintain brain's energy could benefit late-life brain health

byUniversity College LondonDeletion of A2B receptors in hippocampal astrocytes. Credit:Nature(2024). DOI: 10.1038/s41586-024-07611-wA key mechanism which detects when the brain needs

Updated on: July 05,2024

Discovery of cellular mechanism to maintain brain's energy could benefit late-life brain health

byUniversity College LondonDeletion of A2B receptors in hippocampal astrocytes. Credit:Nature(2024). DOI: 10.1038/s41586-024-07611-wA key mechanism which detects when the brain needs

Updated on:July 05,2024

'Lack of cleaning' in brain cells is central to Alzheimer's disease

by University of CopenhagenCredit: CC0 Public DomainAn international research team with representation from the University of Copenhagen has created a better understanding of Alzheimer's. The

Updated on: May 18,2024

'Lack of cleaning' in brain cells is central to Alzheimer's disease

by University of CopenhagenCredit: CC0 Public DomainAn international research team with representation from the University of Copenhagen has created a better understanding of Alzheimer's. The

Updated on:May 18,2024

Protein experts show altered ubiquitin signaling induces hallmarks of sporadic Alzheimer's disease

by Technion - Israel Institute of TechnologyUBB+1accumulates in the early stages of AD postmortem tissue.aImmunofluorescence staining of human tissue (ER = hippocampal complex,

Updated on: March 02,2024

Protein experts show altered ubiquitin signaling induces hallmarks of sporadic Alzheimer's disease

by Technion - Israel Institute of TechnologyUBB+1accumulates in the early stages of AD postmortem tissue.aImmunofluorescence staining of human tissue (ER = hippocampal complex,

Updated on:March 02,2024

Not just a 'bad guy': Researchers discover neuroprotective function of Tau protein

by Rajalaxmi Natarajan,Baylor College of MedicineOverexpression of hTau in glia disrupts LDs and glial cell morphology in response to neuronal ROS. Credit:Nature Neuroscience(2024).

Updated on: September 06,2024

Not just a 'bad guy': Researchers discover neuroprotective function of Tau protein

by Rajalaxmi Natarajan,Baylor College of MedicineOverexpression of hTau in glia disrupts LDs and glial cell morphology in response to neuronal ROS. Credit:Nature Neuroscience(2024).

Updated on:September 06,2024

Traditional foods can bring joy to dementia patients

(HealthDay)—For patients with dementia, traditional dishes can create joy and boost patients' sense of well-being, according to research published online Jan. 11 in theJournal of Clinical Nu

Updated on: February 27,2024

Traditional foods can bring joy to dementia patients

(HealthDay)—For patients with dementia, traditional dishes can create joy and boost patients' sense of well-being, according to research published online Jan. 11 in theJournal of Clinical Nu

Updated on:February 27,2024

Global effort to map the human brain releases first data

byAllen Institute for Brain ScienceBrain slice being prepared for analysis and study. Credit: Erik Dinnel / Allen InstituteThe BRAIN Initiative Cell Atlas Network (BICAN) has launched its first

Updated on: October 16,2024

Global effort to map the human brain releases first data

byAllen Institute for Brain ScienceBrain slice being prepared for analysis and study. Credit: Erik Dinnel / Allen InstituteThe BRAIN Initiative Cell Atlas Network (BICAN) has launched its first

Updated on:October 16,2024

People living with dementia boosted by new guide to care

by Flinders UniversityCredit: Flinders UniversityPeople with dementia and their carers can ask for the care they deserve with confidence after the launch of a new guide to their care rights.The C

Updated on: May 08,2024

People living with dementia boosted by new guide to care

by Flinders UniversityCredit: Flinders UniversityPeople with dementia and their carers can ask for the care they deserve with confidence after the launch of a new guide to their care rights.The C

Updated on:May 08,2024

Lecanemab: Experimental drug is a ray of hope for Alzheimer's disease

by Frederic Calon and Étienne Aumont,The ConversationCredit: AI-generated imageOn Nov. 30, Eisai and Biogen announced theresults of their latest phase 3 clinical trial in Alzheimer's d

Updated on: March 30,2024

Lecanemab: Experimental drug is a ray of hope for Alzheimer's disease

by Frederic Calon and Étienne Aumont,The ConversationCredit: AI-generated imageOn Nov. 30, Eisai and Biogen announced theresults of their latest phase 3 clinical trial in Alzheimer's d

Updated on:March 30,2024

How a gene for obesity affects the brain

byUniversity of MichiganPVHSH2B1→DRN neurocircuit inhibits food intake and obesity. Credit:Advanced Science(2024). DOI: 10.1002/advs.202400437Obesity is a complicated condition, caus

Updated on: July 17,2024

How a gene for obesity affects the brain

byUniversity of MichiganPVHSH2B1→DRN neurocircuit inhibits food intake and obesity. Credit:Advanced Science(2024). DOI: 10.1002/advs.202400437Obesity is a complicated condition, caus

Updated on:July 17,2024