Waste management in the brain may shed light on dementia

by Jim Shelton,Yale UniversityFig. 1: CSF flow speed becomes hyperdynamic with severe CAA. Credit:Nature Aging(2022). DOI: 10.1038/s43587-022-00181-4A new study suggests that a contr

Updated on: May 18,2024

Waste management in the brain may shed light on dementia

by Jim Shelton,Yale UniversityFig. 1: CSF flow speed becomes hyperdynamic with severe CAA. Credit:Nature Aging(2022). DOI: 10.1038/s43587-022-00181-4A new study suggests that a contr

Updated on:May 18,2024

New Alzheimer's disease pathways identified

by University of LübeckPath model of main findings. This path model summarizes the main-effect mediation model. Circles indicate principal components or latent variables, rectangles represent observed

Updated on: March 02,2024

New Alzheimer's disease pathways identified

by University of LübeckPath model of main findings. This path model summarizes the main-effect mediation model. Circles indicate principal components or latent variables, rectangles represent observed

Updated on:March 02,2024

Study reveals key role of TRIO gene in epileptic encephalopathies

byUniversity of MontrealDefective migration of MGE-derived cortical INs inTrio–/–embryos. Credit:Molecular Psychiatry(2024). DOI: 10.1038/s41380-024-02742-yWhat are the m

Updated on: October 09,2024

Study reveals key role of TRIO gene in epileptic encephalopathies

byUniversity of MontrealDefective migration of MGE-derived cortical INs inTrio–/–embryos. Credit:Molecular Psychiatry(2024). DOI: 10.1038/s41380-024-02742-yWhat are the m

Updated on:October 09,2024

Newly discovered mechanism in mitochondria could lead to new treatment for muscle disorders

byUniversity of CopenhagenCredit:Nature Communications(2024). DOI: 10.1038/s41467-024-54183-4Researchers have discovered a mechanism in our cells that is essential to energy producti

Updated on: December 23,2024

Newly discovered mechanism in mitochondria could lead to new treatment for muscle disorders

byUniversity of CopenhagenCredit:Nature Communications(2024). DOI: 10.1038/s41467-024-54183-4Researchers have discovered a mechanism in our cells that is essential to energy producti

Updated on:December 23,2024

Converting brain immune cells into neurons helps mice recover after stroke

by Kyushu UniversityProduction of NeuroD1 in microglial cells induces their development into neurons, therefore decreasing the area of the brain with neuron loss. In scans of the mice brains, neurons

Updated on: January 12,2024

Converting brain immune cells into neurons helps mice recover after stroke

by Kyushu UniversityProduction of NeuroD1 in microglial cells induces their development into neurons, therefore decreasing the area of the brain with neuron loss. In scans of the mice brains, neurons

Updated on:January 12,2024

Hit the sleep 'sweet spot' to keep brain sharp

by Washington University School of MedicineCredit: CC0 Public DomainLike so many other good things in life, sleep is best in moderation. A multiyear study of older adults found that both short an

Updated on: May 13,2024

Hit the sleep 'sweet spot' to keep brain sharp

by Washington University School of MedicineCredit: CC0 Public DomainLike so many other good things in life, sleep is best in moderation. A multiyear study of older adults found that both short an

Updated on:May 13,2024

How does the brain know whether our actions actually make a difference?

by Champalimaud Centre for the UnknownIn "controllable houses", the door's color determines which room it leads to. In contrast, in "uncontrollable houses" the sequence of room

Updated on: February 21,2024

How does the brain know whether our actions actually make a difference?

by Champalimaud Centre for the UnknownIn "controllable houses", the door's color determines which room it leads to. In contrast, in "uncontrollable houses" the sequence of room

Updated on:February 21,2024

Publication highlights care challenges of dementia-related psychosis

by The Gerontological Society of AmericaCredit: CC0 Public DomainIt is estimated that over 2 million Americans with dementia experience delusions (false beliefs) and hallucinations (seeing or hearing

Updated on: May 11,2024

Publication highlights care challenges of dementia-related psychosis

by The Gerontological Society of AmericaCredit: CC0 Public DomainIt is estimated that over 2 million Americans with dementia experience delusions (false beliefs) and hallucinations (seeing or hearing

Updated on:May 11,2024

People living with dementia boosted by new guide to care

by Flinders UniversityCredit: Flinders UniversityPeople with dementia and their carers can ask for the care they deserve with confidence after the launch of a new guide to their care rights.The C

Updated on: May 08,2024

People living with dementia boosted by new guide to care

by Flinders UniversityCredit: Flinders UniversityPeople with dementia and their carers can ask for the care they deserve with confidence after the launch of a new guide to their care rights.The C

Updated on:May 08,2024

Experts explore new approach to vaccine trials and pandemic preparedness

byUniversity of CologneExemplary setup of a VACCELERATE APT on vaccines. Credit:Infection(2024). DOI: 10.1007/s15010-024-02347-1An international consortium of experts led by Translat

Updated on: August 01,2024

Experts explore new approach to vaccine trials and pandemic preparedness

byUniversity of CologneExemplary setup of a VACCELERATE APT on vaccines. Credit:Infection(2024). DOI: 10.1007/s15010-024-02347-1An international consortium of experts led by Translat

Updated on:August 01,2024

Protein experts show altered ubiquitin signaling induces hallmarks of sporadic Alzheimer's disease

by Technion - Israel Institute of TechnologyUBB+1accumulates in the early stages of AD postmortem tissue.aImmunofluorescence staining of human tissue (ER = hippocampal complex,

Updated on: March 02,2024

Protein experts show altered ubiquitin signaling induces hallmarks of sporadic Alzheimer's disease

by Technion - Israel Institute of TechnologyUBB+1accumulates in the early stages of AD postmortem tissue.aImmunofluorescence staining of human tissue (ER = hippocampal complex,

Updated on:March 02,2024

A common marker of neurological diseases may play a role in healthy brains

byNational Institutes of HealthLocalization of α-syn Ser129P and effects of phosphorylation on synaptic targeting. Credit:Neuron(2023). DOI: 10.1016/j.neuron.2023.11.020Researchers h

Updated on: March 13,2024

A common marker of neurological diseases may play a role in healthy brains

byNational Institutes of HealthLocalization of α-syn Ser129P and effects of phosphorylation on synaptic targeting. Credit:Neuron(2023). DOI: 10.1016/j.neuron.2023.11.020Researchers h

Updated on:March 13,2024