Discovery of cellular mechanism to maintain brain's energy could benefit late-life brain health

byUniversity College LondonDeletion of A2B receptors in hippocampal astrocytes. Credit:Nature(2024). DOI: 10.1038/s41586-024-07611-wA key mechanism which detects when the brain needs

Updated on: July 05,2024

Discovery of cellular mechanism to maintain brain's energy could benefit late-life brain health

byUniversity College LondonDeletion of A2B receptors in hippocampal astrocytes. Credit:Nature(2024). DOI: 10.1038/s41586-024-07611-wA key mechanism which detects when the brain needs

Updated on:July 05,2024

Energy storehouses in the brain may be source of Alzheimer's, targets of new therapy

by Arizona State UniversityDiego Mastroeni is a researcher in the ASU-Banner Neurodegenerative Disease Research Center. Credit: Biodesign Institute at Arizona State UniversityAlzheimer's dise

Updated on: May 18,2024

Energy storehouses in the brain may be source of Alzheimer's, targets of new therapy

by Arizona State UniversityDiego Mastroeni is a researcher in the ASU-Banner Neurodegenerative Disease Research Center. Credit: Biodesign Institute at Arizona State UniversityAlzheimer's dise

Updated on:May 18,2024

Protein experts show altered ubiquitin signaling induces hallmarks of sporadic Alzheimer's disease

by Technion - Israel Institute of TechnologyUBB+1accumulates in the early stages of AD postmortem tissue.aImmunofluorescence staining of human tissue (ER = hippocampal complex,

Updated on: March 02,2024

Protein experts show altered ubiquitin signaling induces hallmarks of sporadic Alzheimer's disease

by Technion - Israel Institute of TechnologyUBB+1accumulates in the early stages of AD postmortem tissue.aImmunofluorescence staining of human tissue (ER = hippocampal complex,

Updated on:March 02,2024

Not every young reader's struggle is the same

by Anne Trafton,Massachusetts Institute of TechnologyCredit: Unsplash/CC0 Public DomainMany children struggle to learn to read, and studies have shown that students from a lower socioeconomic st

Updated on: February 03,2024

Not every young reader's struggle is the same

by Anne Trafton,Massachusetts Institute of TechnologyCredit: Unsplash/CC0 Public DomainMany children struggle to learn to read, and studies have shown that students from a lower socioeconomic st

Updated on:February 03,2024

Global effort to map the human brain releases first data

byAllen Institute for Brain ScienceBrain slice being prepared for analysis and study. Credit: Erik Dinnel / Allen InstituteThe BRAIN Initiative Cell Atlas Network (BICAN) has launched its first

Updated on: October 16,2024

Global effort to map the human brain releases first data

byAllen Institute for Brain ScienceBrain slice being prepared for analysis and study. Credit: Erik Dinnel / Allen InstituteThe BRAIN Initiative Cell Atlas Network (BICAN) has launched its first

Updated on:October 16,2024

Publication highlights care challenges of dementia-related psychosis

by The Gerontological Society of AmericaCredit: CC0 Public DomainIt is estimated that over 2 million Americans with dementia experience delusions (false beliefs) and hallucinations (seeing or hearing

Updated on: May 11,2024

Publication highlights care challenges of dementia-related psychosis

by The Gerontological Society of AmericaCredit: CC0 Public DomainIt is estimated that over 2 million Americans with dementia experience delusions (false beliefs) and hallucinations (seeing or hearing

Updated on:May 11,2024

Lecanemab: Experimental drug is a ray of hope for Alzheimer's disease

by Frederic Calon and Étienne Aumont,The ConversationCredit: AI-generated imageOn Nov. 30, Eisai and Biogen announced theresults of their latest phase 3 clinical trial in Alzheimer's d

Updated on: March 30,2024

Lecanemab: Experimental drug is a ray of hope for Alzheimer's disease

by Frederic Calon and Étienne Aumont,The ConversationCredit: AI-generated imageOn Nov. 30, Eisai and Biogen announced theresults of their latest phase 3 clinical trial in Alzheimer's d

Updated on:March 30,2024

Landmark study finds dementia risk varies significantly among racial and ethnic groups

by Kaiser PermanenteDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.In the largest and longest study thus far of ethnic disparities in dementia risk

Updated on: February 27,2024

Landmark study finds dementia risk varies significantly among racial and ethnic groups

by Kaiser PermanenteDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.In the largest and longest study thus far of ethnic disparities in dementia risk

Updated on:February 27,2024

A common marker of neurological diseases may play a role in healthy brains

byNational Institutes of HealthLocalization of α-syn Ser129P and effects of phosphorylation on synaptic targeting. Credit:Neuron(2023). DOI: 10.1016/j.neuron.2023.11.020Researchers h

Updated on: March 13,2024

A common marker of neurological diseases may play a role in healthy brains

byNational Institutes of HealthLocalization of α-syn Ser129P and effects of phosphorylation on synaptic targeting. Credit:Neuron(2023). DOI: 10.1016/j.neuron.2023.11.020Researchers h

Updated on:March 13,2024

Not just a 'bad guy': Researchers discover neuroprotective function of Tau protein

by Rajalaxmi Natarajan,Baylor College of MedicineOverexpression of hTau in glia disrupts LDs and glial cell morphology in response to neuronal ROS. Credit:Nature Neuroscience(2024).

Updated on: September 06,2024

Not just a 'bad guy': Researchers discover neuroprotective function of Tau protein

by Rajalaxmi Natarajan,Baylor College of MedicineOverexpression of hTau in glia disrupts LDs and glial cell morphology in response to neuronal ROS. Credit:Nature Neuroscience(2024).

Updated on:September 06,2024

Study reveals key role of TRIO gene in epileptic encephalopathies

byUniversity of MontrealDefective migration of MGE-derived cortical INs inTrio–/–embryos. Credit:Molecular Psychiatry(2024). DOI: 10.1038/s41380-024-02742-yWhat are the m

Updated on: October 09,2024

Study reveals key role of TRIO gene in epileptic encephalopathies

byUniversity of MontrealDefective migration of MGE-derived cortical INs inTrio–/–embryos. Credit:Molecular Psychiatry(2024). DOI: 10.1038/s41380-024-02742-yWhat are the m

Updated on:October 09,2024

Alzheimer-linked protein complex at super resolution

by VIB (the Flanders Institute for Biotechnology)Credit: CC0 Public DomainWith the advent of super-resolution microscopy, scientists can study close protein associations better than ever before.

Updated on: May 05,2024

Alzheimer-linked protein complex at super resolution

by VIB (the Flanders Institute for Biotechnology)Credit: CC0 Public DomainWith the advent of super-resolution microscopy, scientists can study close protein associations better than ever before.

Updated on:May 05,2024