Protein experts show altered ubiquitin signaling induces hallmarks of sporadic Alzheimer's disease

by Technion - Israel Institute of TechnologyUBB+1accumulates in the early stages of AD postmortem tissue.aImmunofluorescence staining of human tissue (ER = hippocampal complex,

Updated on: March 02,2024

Protein experts show altered ubiquitin signaling induces hallmarks of sporadic Alzheimer's disease

by Technion - Israel Institute of TechnologyUBB+1accumulates in the early stages of AD postmortem tissue.aImmunofluorescence staining of human tissue (ER = hippocampal complex,

Updated on:March 02,2024

Not just a 'bad guy': Researchers discover neuroprotective function of Tau protein

by Rajalaxmi Natarajan,Baylor College of MedicineOverexpression of hTau in glia disrupts LDs and glial cell morphology in response to neuronal ROS. Credit:Nature Neuroscience(2024).

Updated on: September 06,2024

Not just a 'bad guy': Researchers discover neuroprotective function of Tau protein

by Rajalaxmi Natarajan,Baylor College of MedicineOverexpression of hTau in glia disrupts LDs and glial cell morphology in response to neuronal ROS. Credit:Nature Neuroscience(2024).

Updated on:September 06,2024

Alzheimer-linked protein complex at super resolution

by VIB (the Flanders Institute for Biotechnology)Credit: CC0 Public DomainWith the advent of super-resolution microscopy, scientists can study close protein associations better than ever before.

Updated on: May 05,2024

Alzheimer-linked protein complex at super resolution

by VIB (the Flanders Institute for Biotechnology)Credit: CC0 Public DomainWith the advent of super-resolution microscopy, scientists can study close protein associations better than ever before.

Updated on:May 05,2024

Traumatic brain injury may up risk for developing comorbidities

Traumatic brain injury (TBI) of any severity is associated with increased risk of chronic cardiovascular, endocrine, and neurologic comorbidities, according to a study published online April 28 in&nbs

Updated on: February 03,2024

Traumatic brain injury may up risk for developing comorbidities

Traumatic brain injury (TBI) of any severity is associated with increased risk of chronic cardiovascular, endocrine, and neurologic comorbidities, according to a study published online April 28 in&nbs

Updated on:February 03,2024

Discovery of cellular mechanism to maintain brain's energy could benefit late-life brain health

byUniversity College LondonDeletion of A2B receptors in hippocampal astrocytes. Credit:Nature(2024). DOI: 10.1038/s41586-024-07611-wA key mechanism which detects when the brain needs

Updated on: July 05,2024

Discovery of cellular mechanism to maintain brain's energy could benefit late-life brain health

byUniversity College LondonDeletion of A2B receptors in hippocampal astrocytes. Credit:Nature(2024). DOI: 10.1038/s41586-024-07611-wA key mechanism which detects when the brain needs

Updated on:July 05,2024

People living with dementia boosted by new guide to care

by Flinders UniversityCredit: Flinders UniversityPeople with dementia and their carers can ask for the care they deserve with confidence after the launch of a new guide to their care rights.The C

Updated on: May 08,2024

People living with dementia boosted by new guide to care

by Flinders UniversityCredit: Flinders UniversityPeople with dementia and their carers can ask for the care they deserve with confidence after the launch of a new guide to their care rights.The C

Updated on:May 08,2024

Energy storehouses in the brain may be source of Alzheimer's, targets of new therapy

by Arizona State UniversityDiego Mastroeni is a researcher in the ASU-Banner Neurodegenerative Disease Research Center. Credit: Biodesign Institute at Arizona State UniversityAlzheimer's dise

Updated on: May 18,2024

Energy storehouses in the brain may be source of Alzheimer's, targets of new therapy

by Arizona State UniversityDiego Mastroeni is a researcher in the ASU-Banner Neurodegenerative Disease Research Center. Credit: Biodesign Institute at Arizona State UniversityAlzheimer's dise

Updated on:May 18,2024

Lecanemab: Experimental drug is a ray of hope for Alzheimer's disease

by Frederic Calon and Étienne Aumont,The ConversationCredit: AI-generated imageOn Nov. 30, Eisai and Biogen announced theresults of their latest phase 3 clinical trial in Alzheimer's d

Updated on: March 30,2024

Lecanemab: Experimental drug is a ray of hope for Alzheimer's disease

by Frederic Calon and Étienne Aumont,The ConversationCredit: AI-generated imageOn Nov. 30, Eisai and Biogen announced theresults of their latest phase 3 clinical trial in Alzheimer's d

Updated on:March 30,2024

New link between increased astrocytes in the brain and blood in early Alzheimer's disease

by Karolinska InstitutetBrain regions with increased astrocytes that can appear in the blood. Credit: Konstantinos ChiotisA new study shows that the activation of the brain's immune defense c

Updated on: March 02,2024

New link between increased astrocytes in the brain and blood in early Alzheimer's disease

by Karolinska InstitutetBrain regions with increased astrocytes that can appear in the blood. Credit: Konstantinos ChiotisA new study shows that the activation of the brain's immune defense c

Updated on:March 02,2024

Machine learning can predict rate of memory change

by Alzheimer's Research UKIn new research published today, researchers have created a machine learning algorithm that is able to form two distinct groups of people who have early memory probl

Updated on: March 07,2024

Machine learning can predict rate of memory change

by Alzheimer's Research UKIn new research published today, researchers have created a machine learning algorithm that is able to form two distinct groups of people who have early memory probl

Updated on:March 07,2024

Landmark study finds dementia risk varies significantly among racial and ethnic groups

by Kaiser PermanenteDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.In the largest and longest study thus far of ethnic disparities in dementia risk

Updated on: February 27,2024

Landmark study finds dementia risk varies significantly among racial and ethnic groups

by Kaiser PermanenteDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.In the largest and longest study thus far of ethnic disparities in dementia risk

Updated on:February 27,2024

Discovery of cilia defects in ALS patients suggests new treatment path

byVIB (the Flanders Institute for Biotechnology)Motor neurons with damaged primary cilia (green) from patients with the C21orf2 mutation. Credit: VIBAmyotrophic lateral sclerosis (ALS) is a deva

Updated on: January 15,2025

Discovery of cilia defects in ALS patients suggests new treatment path

byVIB (the Flanders Institute for Biotechnology)Motor neurons with damaged primary cilia (green) from patients with the C21orf2 mutation. Credit: VIBAmyotrophic lateral sclerosis (ALS) is a deva

Updated on:January 15,2025