A new approach to treating amyotrophic lateral sclerosis and frontotemporal dementia

by Academia SinicaSchematic representation of mechanisms involved in poly-GR/-PR-induced neuronal degradation and the potential therapeutic action of the sulfated disaccharide SOS. Credit: Academia Si

Updated on: March 28,2024

A new approach to treating amyotrophic lateral sclerosis and frontotemporal dementia

by Academia SinicaSchematic representation of mechanisms involved in poly-GR/-PR-induced neuronal degradation and the potential therapeutic action of the sulfated disaccharide SOS. Credit: Academia Si

Updated on:March 28,2024

Lack of brain shrinkage may help predict who develops dementia with Lewy bodies

by Mayo ClinicDementia with Lewy bodies is a progressive disease that causes hallucinations, decline in mental abilities, rigid muscles, slow movement and tremors. With symptoms similar to Alzhei

Updated on: March 07,2024

Lack of brain shrinkage may help predict who develops dementia with Lewy bodies

by Mayo ClinicDementia with Lewy bodies is a progressive disease that causes hallucinations, decline in mental abilities, rigid muscles, slow movement and tremors. With symptoms similar to Alzhei

Updated on:March 07,2024

Discovery of cilia defects in ALS patients suggests new treatment path

byVIB (the Flanders Institute for Biotechnology)Motor neurons with damaged primary cilia (green) from patients with the C21orf2 mutation. Credit: VIBAmyotrophic lateral sclerosis (ALS) is a deva

Updated on: January 15,2025

Discovery of cilia defects in ALS patients suggests new treatment path

byVIB (the Flanders Institute for Biotechnology)Motor neurons with damaged primary cilia (green) from patients with the C21orf2 mutation. Credit: VIBAmyotrophic lateral sclerosis (ALS) is a deva

Updated on:January 15,2025

Odor biomarker for Alzheimer's disease

by Monell Chemical Senses CenterDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.A new study from the Monell Center, the U.S. Department of Agricultu

Updated on: February 27,2024

Odor biomarker for Alzheimer's disease

by Monell Chemical Senses CenterDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.A new study from the Monell Center, the U.S. Department of Agricultu

Updated on:February 27,2024

Study reveals key role of TRIO gene in epileptic encephalopathies

byUniversity of MontrealDefective migration of MGE-derived cortical INs inTrio–/–embryos. Credit:Molecular Psychiatry(2024). DOI: 10.1038/s41380-024-02742-yWhat are the m

Updated on: October 09,2024

Study reveals key role of TRIO gene in epileptic encephalopathies

byUniversity of MontrealDefective migration of MGE-derived cortical INs inTrio–/–embryos. Credit:Molecular Psychiatry(2024). DOI: 10.1038/s41380-024-02742-yWhat are the m

Updated on:October 09,2024

Often overlooked stem cells hold hidden powers for blood disease treatments

by King Abdullah University of Science and TechnologyResearchers have identified a method to enhance the regenerative capabilities of stem cells found in umbilical cord blood, which could have be

Updated on: March 19,2024

Often overlooked stem cells hold hidden powers for blood disease treatments

by King Abdullah University of Science and TechnologyResearchers have identified a method to enhance the regenerative capabilities of stem cells found in umbilical cord blood, which could have be

Updated on:March 19,2024

Silent synapses are abundant in the adult brain

by Anne Trafton,Massachusetts Institute of TechnologyCredit: Pixabay/CC0 Public DomainMIT neuroscientists have discovered that the adult brain contains millions of "silent synapses"—im

Updated on: February 05,2024

Silent synapses are abundant in the adult brain

by Anne Trafton,Massachusetts Institute of TechnologyCredit: Pixabay/CC0 Public DomainMIT neuroscientists have discovered that the adult brain contains millions of "silent synapses"—im

Updated on:February 05,2024

Certain genetic variant in Alzheimer's disease linked to African ancestry

by Elana GotkineFor individuals of African ancestry, theAPOEε3 R145C missense variant is associated with an increased risk for Alzheimer disease (AD), according to a study published in the

Updated on: April 25,2024

Certain genetic variant in Alzheimer's disease linked to African ancestry

by Elana GotkineFor individuals of African ancestry, theAPOEε3 R145C missense variant is associated with an increased risk for Alzheimer disease (AD), according to a study published in the

Updated on:April 25,2024

Energy storehouses in the brain may be source of Alzheimer's, targets of new therapy

by Arizona State UniversityDiego Mastroeni is a researcher in the ASU-Banner Neurodegenerative Disease Research Center. Credit: Biodesign Institute at Arizona State UniversityAlzheimer's dise

Updated on: May 18,2024

Energy storehouses in the brain may be source of Alzheimer's, targets of new therapy

by Arizona State UniversityDiego Mastroeni is a researcher in the ASU-Banner Neurodegenerative Disease Research Center. Credit: Biodesign Institute at Arizona State UniversityAlzheimer's dise

Updated on:May 18,2024

Genome-wide transcriptome profiling and development of age prediction models in the human brain

by Impact Journals LLCDifferential gene expression analysis overall and by sex. Credit:Aging(2024). DOI: 10.18632/aging.205609A new research paper was published inAgingentitled

Updated on: March 19,2024

Genome-wide transcriptome profiling and development of age prediction models in the human brain

by Impact Journals LLCDifferential gene expression analysis overall and by sex. Credit:Aging(2024). DOI: 10.18632/aging.205609A new research paper was published inAgingentitled

Updated on:March 19,2024

Why are migraines worse during your period? Study points to progesterone, offering a new treatment target

by Suchitra Joshi and Jaideep Kapur,The ConversationHormone levels change throughout the menstrual cycle. Credit:Draper et al. 2018/Scientific Reports,CC BY-SAMigraines are throbbing

Updated on: August 08,2024

Why are migraines worse during your period? Study points to progesterone, offering a new treatment target

by Suchitra Joshi and Jaideep Kapur,The ConversationHormone levels change throughout the menstrual cycle. Credit:Draper et al. 2018/Scientific Reports,CC BY-SAMigraines are throbbing

Updated on:August 08,2024

Tactile imagery used to improve rehabilitation of patients with motor disorders

by Skolkovo Institute of Science and TechnologyBrain MRI projection. Credit: SkoltechSkoltech researchers in collaboration with Immanuel Kant Baltic Federal University, Lomonosov Moscow State Uni

Updated on: February 05,2024

Tactile imagery used to improve rehabilitation of patients with motor disorders

by Skolkovo Institute of Science and TechnologyBrain MRI projection. Credit: SkoltechSkoltech researchers in collaboration with Immanuel Kant Baltic Federal University, Lomonosov Moscow State Uni

Updated on:February 05,2024