Researchers show multiple sclerosis drug can be used as Alzheimer's therapy

by Lindsay Travis,University of KentuckyWorking model for the effect of ponesimod on microglial activation and phagocytosis. Aβ42 binds to TLR4 and induces a complex with S1PR1. S1P co-activates

Updated on: March 02,2024

Researchers show multiple sclerosis drug can be used as Alzheimer's therapy

by Lindsay Travis,University of KentuckyWorking model for the effect of ponesimod on microglial activation and phagocytosis. Aβ42 binds to TLR4 and induces a complex with S1PR1. S1P co-activates

Updated on:March 02,2024

Brain health 'Check-in' tool to help reduce dementia risk

by University College LondonCredit: Alzheimer's Research UKA free new digital tool has been launched by Alzheimer's Research UK, supported by evidence from UCL researchers, to help people

Updated on: April 29,2024

Brain health 'Check-in' tool to help reduce dementia risk

by University College LondonCredit: Alzheimer's Research UKA free new digital tool has been launched by Alzheimer's Research UK, supported by evidence from UCL researchers, to help people

Updated on:April 29,2024

Development of plaques in Alzheimer's disease resolved

by Ruhr-Universitaet-BochumDominik Röhr researches proteins that are altered in Alzheimer’s disease. Credit: Michael SchwettmannA team of researchers from Ruhr-Universität Bochum (RUB) and Vrije

Updated on: April 02,2024

Development of plaques in Alzheimer's disease resolved

by Ruhr-Universitaet-BochumDominik Röhr researches proteins that are altered in Alzheimer’s disease. Credit: Michael SchwettmannA team of researchers from Ruhr-Universität Bochum (RUB) and Vrije

Updated on:April 02,2024

Structural analysis of relevant drug targets for Alzheimer's disease

by Bentham Science PublishersAlzheimer's Disease (AD) is classified as a neurodegenerative non-curable disease that affects millions worldwide. Current drugs have side effects that are significant

Updated on: March 07,2024

Structural analysis of relevant drug targets for Alzheimer's disease

by Bentham Science PublishersAlzheimer's Disease (AD) is classified as a neurodegenerative non-curable disease that affects millions worldwide. Current drugs have side effects that are significant

Updated on:March 07,2024

Loneliness associated with increased risk of dementia in older adults

by NYU Langone HealthChart showing incident of dementia for adults under age 80 without APOE ε4 allele, a genetic risk factor for Alzheimer's disease. Credit: NYU Langone HealthAs social isol

Updated on: June 05,2024

Loneliness associated with increased risk of dementia in older adults

by NYU Langone HealthChart showing incident of dementia for adults under age 80 without APOE ε4 allele, a genetic risk factor for Alzheimer's disease. Credit: NYU Langone HealthAs social isol

Updated on:June 05,2024

A common marker of neurological diseases may play a role in healthy brains

byNational Institutes of HealthLocalization of α-syn Ser129P and effects of phosphorylation on synaptic targeting. Credit:Neuron(2023). DOI: 10.1016/j.neuron.2023.11.020Researchers h

Updated on: March 13,2024

A common marker of neurological diseases may play a role in healthy brains

byNational Institutes of HealthLocalization of α-syn Ser129P and effects of phosphorylation on synaptic targeting. Credit:Neuron(2023). DOI: 10.1016/j.neuron.2023.11.020Researchers h

Updated on:March 13,2024

Blood oxygen levels could explain why memory loss is an early symptom of Alzheimer's

by University of SussexCredit: Fakurian DesignIn a world first, scientists from the University of Sussex have recorded blood oxygen levels in the hippocampus and provided experimental proof for w

Updated on: March 09,2024

Blood oxygen levels could explain why memory loss is an early symptom of Alzheimer's

by University of SussexCredit: Fakurian DesignIn a world first, scientists from the University of Sussex have recorded blood oxygen levels in the hippocampus and provided experimental proof for w

Updated on:March 09,2024

Brain stimulation shows promise for Alzheimer's disease in early trial

by Alzheimer's Research UKPET scan of a human brain with Alzheimer's disease. Credit: public domainScientists in the US have found that electrically stimulating regions of the brain in th

Updated on: May 13,2024

Brain stimulation shows promise for Alzheimer's disease in early trial

by Alzheimer's Research UKPET scan of a human brain with Alzheimer's disease. Credit: public domainScientists in the US have found that electrically stimulating regions of the brain in th

Updated on:May 13,2024

Genes, cardiovascular health each factor into dementia risk

by University of Texas Health Science Center at San AntonioCredit: CC0 Public DomainGenes and cardiovascular health each contribute in an additive way to a person's risk of dementia, U.S. res

Updated on: June 14,2024

Genes, cardiovascular health each factor into dementia risk

by University of Texas Health Science Center at San AntonioCredit: CC0 Public DomainGenes and cardiovascular health each contribute in an additive way to a person's risk of dementia, U.S. res

Updated on:June 14,2024

Alzheimer's drug trial targets toxic proteases from gum disease bacteria in the brain

by Alzheimer's Research UKP. gingivalis colonies grown on blood agar. CC0 Public DomainThe pharmaceutical company, Cortexyme, Inc. has outlined a trial of potential Alzheimer's drug that

Updated on: April 16,2024

Alzheimer's drug trial targets toxic proteases from gum disease bacteria in the brain

by Alzheimer's Research UKP. gingivalis colonies grown on blood agar. CC0 Public DomainThe pharmaceutical company, Cortexyme, Inc. has outlined a trial of potential Alzheimer's drug that

Updated on:April 16,2024

Uncovering the molecular mechanism behind synapse loss in Alzheimer's disease

by Korea Brain Research InstituteCredit: Unsplash/CC0 Public DomainKorea Brain Research Institute (KBRI, Pann-Ghill Suh (President)) announced that Dr. Kea Joo Lee and Dr. You-Na Jang of the Neural Ci

Updated on: July 01,2024

Uncovering the molecular mechanism behind synapse loss in Alzheimer's disease

by Korea Brain Research InstituteCredit: Unsplash/CC0 Public DomainKorea Brain Research Institute (KBRI, Pann-Ghill Suh (President)) announced that Dr. Kea Joo Lee and Dr. You-Na Jang of the Neural Ci

Updated on:July 01,2024

Poor neighborhoods linked to elevated dementia risk and faster brain aging

by Duke UniversityCredit: CC0 Public DomainLiving in a poorer neighborhood is linked to accelerated brain aging and increased dementia risk early in life, regardless of income level or education,

Updated on: March 19,2024

Poor neighborhoods linked to elevated dementia risk and faster brain aging

by Duke UniversityCredit: CC0 Public DomainLiving in a poorer neighborhood is linked to accelerated brain aging and increased dementia risk early in life, regardless of income level or education,

Updated on:March 19,2024