Machine learning models rank predictive risks for Alzheimer's disease

by Emily Caldwell,The Ohio State UniversityFeature importance and impact of top 20 most important features for different age groups. SHAP global feature importance bar chart (left) and SHAP loca

Updated on: June 14,2024 5

Machine learning models rank predictive risks for Alzheimer's disease

by Emily Caldwell,The Ohio State UniversityFeature importance and impact of top 20 most important features for different age groups. SHAP global feature importance bar chart (left) and SHAP loca

Updated on:June 14,2024 5

Overwhelmed? Your astrocytes can help with that

by University of California, San FranciscoDissection of astrocyte Ca2+and behavioral state. (a) Representative 2P mean projection image from one ten-minute recording of in vivo astrocyte Gc

Updated on: February 05,2024 6

Overwhelmed? Your astrocytes can help with that

by University of California, San FranciscoDissection of astrocyte Ca2+and behavioral state. (a) Representative 2P mean projection image from one ten-minute recording of in vivo astrocyte Gc

Updated on:February 05,2024 6

Disrupted circadian regulation of cognition in Alzheimer's disease

by Emily Caldwell,The Ohio State UniversityCredit: AI-generated imageCircadian dysfunction linked to Alzheimer's disease is known to disrupt sleep and daily activity patterns. New research i

Updated on: April 18,2024 12

Disrupted circadian regulation of cognition in Alzheimer's disease

by Emily Caldwell,The Ohio State UniversityCredit: AI-generated imageCircadian dysfunction linked to Alzheimer's disease is known to disrupt sleep and daily activity patterns. New research i

Updated on:April 18,2024 12

Publication highlights care challenges of dementia-related psychosis

by The Gerontological Society of AmericaCredit: CC0 Public DomainIt is estimated that over 2 million Americans with dementia experience delusions (false beliefs) and hallucinations (seeing or hearing

Updated on: May 11,2024 7

Publication highlights care challenges of dementia-related psychosis

by The Gerontological Society of AmericaCredit: CC0 Public DomainIt is estimated that over 2 million Americans with dementia experience delusions (false beliefs) and hallucinations (seeing or hearing

Updated on:May 11,2024 7

Different 'subtypes' of Alzheimer's may be linked to different modifications of the tau protein

by Massachusetts General HospitalDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.A new study reveals a possible biological reason that Alzheimer&#39

Updated on: April 07,2024 15

Different 'subtypes' of Alzheimer's may be linked to different modifications of the tau protein

by Massachusetts General HospitalDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.A new study reveals a possible biological reason that Alzheimer&#39

Updated on:April 07,2024 15

Clinicians should address needs of family caregivers of persons with dementia

by University of Pennsylvania School of NursingMore than 15 million family members and other unpaid caregivers provide care to persons living with dementia in the United States. Yet the current h

Updated on: March 07,2024 13

Clinicians should address needs of family caregivers of persons with dementia

by University of Pennsylvania School of NursingMore than 15 million family members and other unpaid caregivers provide care to persons living with dementia in the United States. Yet the current h

Updated on:March 07,2024 13

Emergency but not elective hospital admissions linked to faster memory and thinking decline

by Alzheimer's Research UKResearchers in Chicago have investigated the link between hospital admissions and memory and thinking problems. Existing research indicates that older people are at

Updated on: March 07,2024 13

Emergency but not elective hospital admissions linked to faster memory and thinking decline

by Alzheimer's Research UKResearchers in Chicago have investigated the link between hospital admissions and memory and thinking problems. Existing research indicates that older people are at

Updated on:March 07,2024 13

Deaths from Alzheimer's disease in Scotland increase by 33.4% in one year

by Alzheimer's Research UKDeaths from Alzheimer's in Scotland have soared by 33.4 percent in a year, according to new statistics released by the National Records of Scotland today.Provisi

Updated on: March 07,2024 14

Deaths from Alzheimer's disease in Scotland increase by 33.4% in one year

by Alzheimer's Research UKDeaths from Alzheimer's in Scotland have soared by 33.4 percent in a year, according to new statistics released by the National Records of Scotland today.Provisi

Updated on:March 07,2024 14

Antibody therapy inspired by patient case reduces tau tangles in a preclinical model of Alzheimer's disease

by Mass General BrighamCredit: Pixabay/Pete Linforth.A team led by researchers from Mass General Brigham reports promising results for a monoclonal antibody that takes aim at a new target for Alz

Updated on: March 02,2024 18

Antibody therapy inspired by patient case reduces tau tangles in a preclinical model of Alzheimer's disease

by Mass General BrighamCredit: Pixabay/Pete Linforth.A team led by researchers from Mass General Brigham reports promising results for a monoclonal antibody that takes aim at a new target for Alz

Updated on:March 02,2024 18

Simple test could help predict risk of Alzheimer's disease 20 years in advance

by The Australian National Universitya) Sketch of protein translocation through a SiNx nanopore membrane. The proteins in a buffered electrolyte solution are placed in the cis and trans channels

Updated on: March 02,2024 12

Simple test could help predict risk of Alzheimer's disease 20 years in advance

by The Australian National Universitya) Sketch of protein translocation through a SiNx nanopore membrane. The proteins in a buffered electrolyte solution are placed in the cis and trans channels

Updated on:March 02,2024 12

Novel method facilitates study of oxidized lipids involved in neurodegenerative diseases

NOVEMBER 15, 2023byFAPESPGraphical abstract. Credit:Free Radical Biology and Medicine(2023). DOI: 10.1016/j.freeradbiomed.2023.08.019Lipids are a diversified class of biomolecules wi

Updated on: March 28,2024 4

Novel method facilitates study of oxidized lipids involved in neurodegenerative diseases

NOVEMBER 15, 2023byFAPESPGraphical abstract. Credit:Free Radical Biology and Medicine(2023). DOI: 10.1016/j.freeradbiomed.2023.08.019Lipids are a diversified class of biomolecules wi

Updated on:March 28,2024 4

A common marker of neurological diseases may play a role in healthy brains

byNational Institutes of HealthLocalization of α-syn Ser129P and effects of phosphorylation on synaptic targeting. Credit:Neuron(2023). DOI: 10.1016/j.neuron.2023.11.020Researchers h

Updated on: March 13,2024 11

A common marker of neurological diseases may play a role in healthy brains

byNational Institutes of HealthLocalization of α-syn Ser129P and effects of phosphorylation on synaptic targeting. Credit:Neuron(2023). DOI: 10.1016/j.neuron.2023.11.020Researchers h

Updated on:March 13,2024 11