New drug targets for Alzheimer's identified from cerebrospinal fluid

by Mark Reynolds,Washington University School of MedicineCellular localization of immune and lysosomal proteins. Credit:Nature Genetics(2024). DOI: 10.1038/s41588-024-01972-8A multit

Updated on: November 22,2024

New drug targets for Alzheimer's identified from cerebrospinal fluid

by Mark Reynolds,Washington University School of MedicineCellular localization of immune and lysosomal proteins. Credit:Nature Genetics(2024). DOI: 10.1038/s41588-024-01972-8A multit

Updated on:November 22,2024

Study highlight potential links between COVID-19 and Alzheimer's disease

by WileyCredit: Pixabay/Pete Linforth.The various neurological symptoms that patients with COVID-19 have experienced suggest that viral infections may increase the risk of neurodegeneration, whic

Updated on: March 02,2024

Study highlight potential links between COVID-19 and Alzheimer's disease

by WileyCredit: Pixabay/Pete Linforth.The various neurological symptoms that patients with COVID-19 have experienced suggest that viral infections may increase the risk of neurodegeneration, whic

Updated on:March 02,2024

BACE-Inhibitor successfully tested in Alzheimer's animal model

by Technical University MunichMarc Aurel Busche at the two-photon microscope, which allows to visualize nerve cells with high temporal and spatial resolution in the intact brain. Credit: Kurt Bau

Updated on: March 19,2024

BACE-Inhibitor successfully tested in Alzheimer's animal model

by Technical University MunichMarc Aurel Busche at the two-photon microscope, which allows to visualize nerve cells with high temporal and spatial resolution in the intact brain. Credit: Kurt Bau

Updated on:March 19,2024

Dementia gene linked to connections in brain

by University of EdinburghCredit: CC0 Public DomainInsights into how a gene that increases the risk of Alzheimer's disease disrupts brain cells have been revealed by scientists.Brain tissue f

Updated on: May 06,2024

Dementia gene linked to connections in brain

by University of EdinburghCredit: CC0 Public DomainInsights into how a gene that increases the risk of Alzheimer's disease disrupts brain cells have been revealed by scientists.Brain tissue f

Updated on:May 06,2024

No new drugs for Alzheimer's disease in 15 years

by Vanessa Jane Hall,ScienceNordicCredit: AI-generated imageHow often to you read headlines proclaiming the arrival of a new, ground-breaking treatment for Alzheimer's?The answer is probably

Updated on: March 13,2024

No new drugs for Alzheimer's disease in 15 years

by Vanessa Jane Hall,ScienceNordicCredit: AI-generated imageHow often to you read headlines proclaiming the arrival of a new, ground-breaking treatment for Alzheimer's?The answer is probably

Updated on:March 13,2024

Optogenetics approach reveals how alcohol use disorder impairs cognitive flexibility

by Danielle Michaud,Texas A&M UniversityExcessive alcohol intake reduces thalamically evoked burst-pause response in DMS CINs and impairs reversal of operant conditioning. Credit:Scien

Updated on: January 15,2025

Optogenetics approach reveals how alcohol use disorder impairs cognitive flexibility

by Danielle Michaud,Texas A&M UniversityExcessive alcohol intake reduces thalamically evoked burst-pause response in DMS CINs and impairs reversal of operant conditioning. Credit:Scien

Updated on:January 15,2025

Curcumin for amyloidosis and lipid metabolism—a novel insight

by Shinshu UniversitySchematic diagram of the effect of curcumin mediated by PPARa pathway in AApoAII amyloidosis model mouse. Credit: Jian DaiCurcumin is a polyphenol compound produced by plants of t

Updated on: June 24,2024

Curcumin for amyloidosis and lipid metabolism—a novel insight

by Shinshu UniversitySchematic diagram of the effect of curcumin mediated by PPARa pathway in AApoAII amyloidosis model mouse. Credit: Jian DaiCurcumin is a polyphenol compound produced by plants of t

Updated on:June 24,2024

Protein shapes matter in Alzheimer's research

by Allison Mills,Michigan Technological UniversityCellular toxicity, which is higher in amyloid amorphous aggregates, shows that small changes in protein folding chemistry can cause differences

Updated on: April 16,2024

Protein shapes matter in Alzheimer's research

by Allison Mills,Michigan Technological UniversityCellular toxicity, which is higher in amyloid amorphous aggregates, shows that small changes in protein folding chemistry can cause differences

Updated on:April 16,2024

Brain changes may help track dementia, even before diagnosis

by American Academy of NeurologyCredit: CC0 Public DomainEven before a dementia diagnosis, people with mild cognitive impairment may have different changes in the brain depending on what type of

Updated on: May 18,2024

Brain changes may help track dementia, even before diagnosis

by American Academy of NeurologyCredit: CC0 Public DomainEven before a dementia diagnosis, people with mild cognitive impairment may have different changes in the brain depending on what type of

Updated on:May 18,2024

Immune cells in the brain play key role in relationship between gut microbes and b-amyloid deposits

by University of Chicago Medical CenterMicroglia in the brain of male mice with Alzheimer's Disease have a “neurodegenerative” appearance and is associated with amyloid beta plaques in the br

Updated on: May 18,2024

Immune cells in the brain play key role in relationship between gut microbes and b-amyloid deposits

by University of Chicago Medical CenterMicroglia in the brain of male mice with Alzheimer's Disease have a “neurodegenerative” appearance and is associated with amyloid beta plaques in the br

Updated on:May 18,2024

Build-up of brain proteins affects genes in Alzheimer's disease

by University of ExeterImage of tau build-up in mouse brain. At two months. Credit: University of ExeterNew research has shed fresh light on how the build-up of two proteins in the brain might af

Updated on: May 18,2024

Build-up of brain proteins affects genes in Alzheimer's disease

by University of ExeterImage of tau build-up in mouse brain. At two months. Credit: University of ExeterNew research has shed fresh light on how the build-up of two proteins in the brain might af

Updated on:May 18,2024

Research team develops soft and highly durable brain electrodes that could be used in treatment

by DGIST (Daegu Gyeongbuk Institute of Science and Technology)ECoG electrode array based on PDMS-based substrates treated in two different ways. (a) Fabrication of ECoG electrodes based on surface-tre

Updated on: March 30,2024

Research team develops soft and highly durable brain electrodes that could be used in treatment

by DGIST (Daegu Gyeongbuk Institute of Science and Technology)ECoG electrode array based on PDMS-based substrates treated in two different ways. (a) Fabrication of ECoG electrodes based on surface-tre

Updated on:March 30,2024