Genetic marker that often points to heart disease and Alzheimer's may have fertility benefit

by Arizona State UniversityBen Trumble inside ASU's lab at the School of Human Evolution and Social Change. Credit: Charlie Leight/ASU NewsPrevious research has revealed that the Apolipoprote

Updated on: July 01,2024

Genetic marker that often points to heart disease and Alzheimer's may have fertility benefit

by Arizona State UniversityBen Trumble inside ASU's lab at the School of Human Evolution and Social Change. Credit: Charlie Leight/ASU NewsPrevious research has revealed that the Apolipoprote

Updated on:July 01,2024

Researchers show multiple sclerosis drug can be used as Alzheimer's therapy

by Lindsay Travis,University of KentuckyWorking model for the effect of ponesimod on microglial activation and phagocytosis. Aβ42 binds to TLR4 and induces a complex with S1PR1. S1P co-activates

Updated on: March 02,2024

Researchers show multiple sclerosis drug can be used as Alzheimer's therapy

by Lindsay Travis,University of KentuckyWorking model for the effect of ponesimod on microglial activation and phagocytosis. Aβ42 binds to TLR4 and induces a complex with S1PR1. S1P co-activates

Updated on:March 02,2024

How antidepressants, ketamine and psychedelic drugs may make brains more flexible—new research

by Barbara Jacquelyn Sahakian and Christelle Langley,The ConversationCredit: Juan Gaertner/ShutterstockThe first-line pharmacological treatment for major depressive disorder (MDD) are antidepres

Updated on: January 12,2024

How antidepressants, ketamine and psychedelic drugs may make brains more flexible—new research

by Barbara Jacquelyn Sahakian and Christelle Langley,The ConversationCredit: Juan Gaertner/ShutterstockThe first-line pharmacological treatment for major depressive disorder (MDD) are antidepres

Updated on:January 12,2024

Dementia researchers call for urgent action to prevent setbacks in treatment search

by Alzheimer's Research UKCredit: CC0 Public DomainNearly 300 researchers have called for urgent government action to prevent a major setback to the search for new dementia treatments as a re

Updated on: May 11,2024

Dementia researchers call for urgent action to prevent setbacks in treatment search

by Alzheimer's Research UKCredit: CC0 Public DomainNearly 300 researchers have called for urgent government action to prevent a major setback to the search for new dementia treatments as a re

Updated on:May 11,2024

Mitochondrial roles in antiviral immunity modify manifestations of neurological diseases

by University of HelsinkiSchematic of antiviral innate immune signaling responses to viral PAMPs. Credit:Nature(2024). DOI: 10.1038/s41586-024-07260-zA multidisciplinary team of scien

Updated on: April 06,2024

Mitochondrial roles in antiviral immunity modify manifestations of neurological diseases

by University of HelsinkiSchematic of antiviral innate immune signaling responses to viral PAMPs. Credit:Nature(2024). DOI: 10.1038/s41586-024-07260-zA multidisciplinary team of scien

Updated on:April 06,2024

New visual technique could advance early detection of neurodegenerative diseases

byUniversity of MinnesotaIntroduction and overview of Cap-QuIC method. Credit:npj Biosensing(2024). DOI: 10.1038/s44328-024-00003-0Researchers at the University of Minnesota have dev

Updated on: August 08,2024

New visual technique could advance early detection of neurodegenerative diseases

byUniversity of MinnesotaIntroduction and overview of Cap-QuIC method. Credit:npj Biosensing(2024). DOI: 10.1038/s44328-024-00003-0Researchers at the University of Minnesota have dev

Updated on:August 08,2024

How humans continuously adapt while walking stably

byMassachusetts Institute of TechnologyA hierarchical framework for locomotor adaptation. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-53416-wResearchers have develope

Updated on: January 15,2025

How humans continuously adapt while walking stably

byMassachusetts Institute of TechnologyA hierarchical framework for locomotor adaptation. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-53416-wResearchers have develope

Updated on:January 15,2025

Machine learning gives nuanced view of Alzheimer's stages

by David Nutt,Cornell UniversityFeed-forward, fully-connected neural network architecture. Nonlinear models have rectified linear units (ReLU) between layers. Final layer implements a soft-max.

Updated on: June 14,2024

Machine learning gives nuanced view of Alzheimer's stages

by David Nutt,Cornell UniversityFeed-forward, fully-connected neural network architecture. Nonlinear models have rectified linear units (ReLU) between layers. Final layer implements a soft-max.

Updated on:June 14,2024

Leaders in Alzheimer's research herald the dawn of a new era in drug development based on biology of aging

by Alzheimer's Drug Discovery FoundationCredit: Pixabay/CC0 Public DomainA combination of drugs will be needed to effectively treat or prevent Alzheimer's disease and leading experts say we ha

Updated on: April 16,2024

Leaders in Alzheimer's research herald the dawn of a new era in drug development based on biology of aging

by Alzheimer's Drug Discovery FoundationCredit: Pixabay/CC0 Public DomainA combination of drugs will be needed to effectively treat or prevent Alzheimer's disease and leading experts say we ha

Updated on:April 16,2024

The molecular mechanisms of Alzheimer's

by Pacific Northwest National LaboratoryFigure 1 in the paper outlines the quantitative proteomic pipeline for O-GlcNAc analysis. stochastic kinetic simulations (red) and simulations using the co

Updated on: April 07,2024

The molecular mechanisms of Alzheimer's

by Pacific Northwest National LaboratoryFigure 1 in the paper outlines the quantitative proteomic pipeline for O-GlcNAc analysis. stochastic kinetic simulations (red) and simulations using the co

Updated on:April 07,2024

CRISPR helps identify potential Alzheimer's-related protein

by University of TokyoCredit: CC0 Public DomainExperts at the University of Tokyo have identified a new protein in the pathway that leads to Alzheimer's disease. Researchers used the "mo

Updated on: March 30,2024

CRISPR helps identify potential Alzheimer's-related protein

by University of TokyoCredit: CC0 Public DomainExperts at the University of Tokyo have identified a new protein in the pathway that leads to Alzheimer's disease. Researchers used the "mo

Updated on:March 30,2024

From Alzheimer's to autism, nuclear neurology could launch revolution in diagnosing and treating brain diseases

by Ellen Goldbaum,University at BuffaloImage of glucose metabolism PET overlaid on CT in an Alzheimer's patient with mild dementia. Green arrow points to regional hypometabolism in the media

Updated on: May 13,2024

From Alzheimer's to autism, nuclear neurology could launch revolution in diagnosing and treating brain diseases

by Ellen Goldbaum,University at BuffaloImage of glucose metabolism PET overlaid on CT in an Alzheimer's patient with mild dementia. Green arrow points to regional hypometabolism in the media

Updated on:May 13,2024