How antidepressants, ketamine and psychedelic drugs may make brains more flexible—new research

by Barbara Jacquelyn Sahakian and Christelle Langley,The ConversationCredit: Juan Gaertner/ShutterstockThe first-line pharmacological treatment for major depressive disorder (MDD) are antidepres

Updated on: January 12,2024

How antidepressants, ketamine and psychedelic drugs may make brains more flexible—new research

by Barbara Jacquelyn Sahakian and Christelle Langley,The ConversationCredit: Juan Gaertner/ShutterstockThe first-line pharmacological treatment for major depressive disorder (MDD) are antidepres

Updated on:January 12,2024

Machine learning gives nuanced view of Alzheimer's stages

by David Nutt,Cornell UniversityFeed-forward, fully-connected neural network architecture. Nonlinear models have rectified linear units (ReLU) between layers. Final layer implements a soft-max.

Updated on: June 14,2024

Machine learning gives nuanced view of Alzheimer's stages

by David Nutt,Cornell UniversityFeed-forward, fully-connected neural network architecture. Nonlinear models have rectified linear units (ReLU) between layers. Final layer implements a soft-max.

Updated on:June 14,2024

Opioid analgesics increase the risk of pneumonia among persons with Alzheimer's disease

by University of Eastern FinlandCredit: CC0 Public DomainOpioid analgesics were associated with a 30 percent increase in the risk of pneumonia in persons with Alzheimer's disease, a recent st

Updated on: April 25,2024

Opioid analgesics increase the risk of pneumonia among persons with Alzheimer's disease

by University of Eastern FinlandCredit: CC0 Public DomainOpioid analgesics were associated with a 30 percent increase in the risk of pneumonia in persons with Alzheimer's disease, a recent st

Updated on:April 25,2024

Immune cells in the brain play key role in relationship between gut microbes and b-amyloid deposits

by University of Chicago Medical CenterMicroglia in the brain of male mice with Alzheimer's Disease have a “neurodegenerative” appearance and is associated with amyloid beta plaques in the br

Updated on: May 18,2024

Immune cells in the brain play key role in relationship between gut microbes and b-amyloid deposits

by University of Chicago Medical CenterMicroglia in the brain of male mice with Alzheimer's Disease have a “neurodegenerative” appearance and is associated with amyloid beta plaques in the br

Updated on:May 18,2024

Build-up of brain proteins affects genes in Alzheimer's disease

by University of ExeterImage of tau build-up in mouse brain. At two months. Credit: University of ExeterNew research has shed fresh light on how the build-up of two proteins in the brain might af

Updated on: May 18,2024

Build-up of brain proteins affects genes in Alzheimer's disease

by University of ExeterImage of tau build-up in mouse brain. At two months. Credit: University of ExeterNew research has shed fresh light on how the build-up of two proteins in the brain might af

Updated on:May 18,2024

The molecular mechanisms of Alzheimer's

by Pacific Northwest National LaboratoryFigure 1 in the paper outlines the quantitative proteomic pipeline for O-GlcNAc analysis. stochastic kinetic simulations (red) and simulations using the co

Updated on: April 07,2024

The molecular mechanisms of Alzheimer's

by Pacific Northwest National LaboratoryFigure 1 in the paper outlines the quantitative proteomic pipeline for O-GlcNAc analysis. stochastic kinetic simulations (red) and simulations using the co

Updated on:April 07,2024

New visual technique could advance early detection of neurodegenerative diseases

byUniversity of MinnesotaIntroduction and overview of Cap-QuIC method. Credit:npj Biosensing(2024). DOI: 10.1038/s44328-024-00003-0Researchers at the University of Minnesota have dev

Updated on: August 08,2024

New visual technique could advance early detection of neurodegenerative diseases

byUniversity of MinnesotaIntroduction and overview of Cap-QuIC method. Credit:npj Biosensing(2024). DOI: 10.1038/s44328-024-00003-0Researchers at the University of Minnesota have dev

Updated on:August 08,2024

Researchers show multiple sclerosis drug can be used as Alzheimer's therapy

by Lindsay Travis,University of KentuckyWorking model for the effect of ponesimod on microglial activation and phagocytosis. Aβ42 binds to TLR4 and induces a complex with S1PR1. S1P co-activates

Updated on: March 02,2024

Researchers show multiple sclerosis drug can be used as Alzheimer's therapy

by Lindsay Travis,University of KentuckyWorking model for the effect of ponesimod on microglial activation and phagocytosis. Aβ42 binds to TLR4 and induces a complex with S1PR1. S1P co-activates

Updated on:March 02,2024

How humans continuously adapt while walking stably

byMassachusetts Institute of TechnologyA hierarchical framework for locomotor adaptation. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-53416-wResearchers have develope

Updated on: January 15,2025

How humans continuously adapt while walking stably

byMassachusetts Institute of TechnologyA hierarchical framework for locomotor adaptation. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-53416-wResearchers have develope

Updated on:January 15,2025

From Alzheimer's to autism, nuclear neurology could launch revolution in diagnosing and treating brain diseases

by Ellen Goldbaum,University at BuffaloImage of glucose metabolism PET overlaid on CT in an Alzheimer's patient with mild dementia. Green arrow points to regional hypometabolism in the media

Updated on: May 13,2024

From Alzheimer's to autism, nuclear neurology could launch revolution in diagnosing and treating brain diseases

by Ellen Goldbaum,University at BuffaloImage of glucose metabolism PET overlaid on CT in an Alzheimer's patient with mild dementia. Green arrow points to regional hypometabolism in the media

Updated on:May 13,2024

CRISPR helps identify potential Alzheimer's-related protein

by University of TokyoCredit: CC0 Public DomainExperts at the University of Tokyo have identified a new protein in the pathway that leads to Alzheimer's disease. Researchers used the "mo

Updated on: March 30,2024

CRISPR helps identify potential Alzheimer's-related protein

by University of TokyoCredit: CC0 Public DomainExperts at the University of Tokyo have identified a new protein in the pathway that leads to Alzheimer's disease. Researchers used the "mo

Updated on:March 30,2024

Couch potatoes face same chance of dementia as those with genetic risk factors

by McMaster UniversityJennifer Heisz, assistant professor of kinesiology, McMaster University Credit: McMaster UniversitySedentary older adults with no genetic risk factors for dementia may be ju

Updated on: March 09,2024

Couch potatoes face same chance of dementia as those with genetic risk factors

by McMaster UniversityJennifer Heisz, assistant professor of kinesiology, McMaster University Credit: McMaster UniversitySedentary older adults with no genetic risk factors for dementia may be ju

Updated on:March 09,2024