Dementia researchers call for urgent action to prevent setbacks in treatment search

by Alzheimer's Research UKCredit: CC0 Public DomainNearly 300 researchers have called for urgent government action to prevent a major setback to the search for new dementia treatments as a re

Updated on: May 11,2024

Dementia researchers call for urgent action to prevent setbacks in treatment search

by Alzheimer's Research UKCredit: CC0 Public DomainNearly 300 researchers have called for urgent government action to prevent a major setback to the search for new dementia treatments as a re

Updated on:May 11,2024

Immune cells in the brain play key role in relationship between gut microbes and b-amyloid deposits

by University of Chicago Medical CenterMicroglia in the brain of male mice with Alzheimer's Disease have a “neurodegenerative” appearance and is associated with amyloid beta plaques in the br

Updated on: May 18,2024

Immune cells in the brain play key role in relationship between gut microbes and b-amyloid deposits

by University of Chicago Medical CenterMicroglia in the brain of male mice with Alzheimer's Disease have a “neurodegenerative” appearance and is associated with amyloid beta plaques in the br

Updated on:May 18,2024

CRISPR helps identify potential Alzheimer's-related protein

by University of TokyoCredit: CC0 Public DomainExperts at the University of Tokyo have identified a new protein in the pathway that leads to Alzheimer's disease. Researchers used the "mo

Updated on: March 30,2024

CRISPR helps identify potential Alzheimer's-related protein

by University of TokyoCredit: CC0 Public DomainExperts at the University of Tokyo have identified a new protein in the pathway that leads to Alzheimer's disease. Researchers used the "mo

Updated on:March 30,2024

Genetic marker that often points to heart disease and Alzheimer's may have fertility benefit

by Arizona State UniversityBen Trumble inside ASU's lab at the School of Human Evolution and Social Change. Credit: Charlie Leight/ASU NewsPrevious research has revealed that the Apolipoprote

Updated on: July 01,2024

Genetic marker that often points to heart disease and Alzheimer's may have fertility benefit

by Arizona State UniversityBen Trumble inside ASU's lab at the School of Human Evolution and Social Change. Credit: Charlie Leight/ASU NewsPrevious research has revealed that the Apolipoprote

Updated on:July 01,2024

Poor gut health may drive multiple sclerosis—better diet may ease it

by Rutgers UniversityDevelopment of colitis in spontaneous EAE mice. (A) Swollen colon in spontaneous EAE mice. (B) H&E histopathology of swollen colon isolated from spontaneous EAE and non-E

Updated on: February 03,2024

Poor gut health may drive multiple sclerosis—better diet may ease it

by Rutgers UniversityDevelopment of colitis in spontaneous EAE mice. (A) Swollen colon in spontaneous EAE mice. (B) H&E histopathology of swollen colon isolated from spontaneous EAE and non-E

Updated on:February 03,2024

Researchers show multiple sclerosis drug can be used as Alzheimer's therapy

by Lindsay Travis,University of KentuckyWorking model for the effect of ponesimod on microglial activation and phagocytosis. Aβ42 binds to TLR4 and induces a complex with S1PR1. S1P co-activates

Updated on: March 02,2024

Researchers show multiple sclerosis drug can be used as Alzheimer's therapy

by Lindsay Travis,University of KentuckyWorking model for the effect of ponesimod on microglial activation and phagocytosis. Aβ42 binds to TLR4 and induces a complex with S1PR1. S1P co-activates

Updated on:March 02,2024

Examining dementia risk in adults with intellectual disability

by Okayama UniversityLittle is known about the risk factors of dementia in people diagnosed with intellectual disabilities. Researchers at Okayama University Hospital, Okayama University, and Asa

Updated on: March 02,2024

Examining dementia risk in adults with intellectual disability

by Okayama UniversityLittle is known about the risk factors of dementia in people diagnosed with intellectual disabilities. Researchers at Okayama University Hospital, Okayama University, and Asa

Updated on:March 02,2024

Mitochondrial roles in antiviral immunity modify manifestations of neurological diseases

by University of HelsinkiSchematic of antiviral innate immune signaling responses to viral PAMPs. Credit:Nature(2024). DOI: 10.1038/s41586-024-07260-zA multidisciplinary team of scien

Updated on: April 06,2024

Mitochondrial roles in antiviral immunity modify manifestations of neurological diseases

by University of HelsinkiSchematic of antiviral innate immune signaling responses to viral PAMPs. Credit:Nature(2024). DOI: 10.1038/s41586-024-07260-zA multidisciplinary team of scien

Updated on:April 06,2024

The molecular mechanisms of Alzheimer's

by Pacific Northwest National LaboratoryFigure 1 in the paper outlines the quantitative proteomic pipeline for O-GlcNAc analysis. stochastic kinetic simulations (red) and simulations using the co

Updated on: April 07,2024

The molecular mechanisms of Alzheimer's

by Pacific Northwest National LaboratoryFigure 1 in the paper outlines the quantitative proteomic pipeline for O-GlcNAc analysis. stochastic kinetic simulations (red) and simulations using the co

Updated on:April 07,2024

Build-up of brain proteins affects genes in Alzheimer's disease

by University of ExeterImage of tau build-up in mouse brain. At two months. Credit: University of ExeterNew research has shed fresh light on how the build-up of two proteins in the brain might af

Updated on: May 18,2024

Build-up of brain proteins affects genes in Alzheimer's disease

by University of ExeterImage of tau build-up in mouse brain. At two months. Credit: University of ExeterNew research has shed fresh light on how the build-up of two proteins in the brain might af

Updated on:May 18,2024

New visual technique could advance early detection of neurodegenerative diseases

byUniversity of MinnesotaIntroduction and overview of Cap-QuIC method. Credit:npj Biosensing(2024). DOI: 10.1038/s44328-024-00003-0Researchers at the University of Minnesota have dev

Updated on: August 08,2024

New visual technique could advance early detection of neurodegenerative diseases

byUniversity of MinnesotaIntroduction and overview of Cap-QuIC method. Credit:npj Biosensing(2024). DOI: 10.1038/s44328-024-00003-0Researchers at the University of Minnesota have dev

Updated on:August 08,2024

New study shows promising diagnosis of multiple sclerosis from images of the eye

byDurham UniversitySaliency maps generated for eight SLO images and OCT thickness maps of the total retina of (A) HC and (B) MS subjects from the test dataset when the best-performing model trai

Updated on: July 31,2024

New study shows promising diagnosis of multiple sclerosis from images of the eye

byDurham UniversitySaliency maps generated for eight SLO images and OCT thickness maps of the total retina of (A) HC and (B) MS subjects from the test dataset when the best-performing model trai

Updated on:July 31,2024