Immune cells in the brain play key role in relationship between gut microbes and b-amyloid deposits

by University of Chicago Medical CenterMicroglia in the brain of male mice with Alzheimer's Disease have a “neurodegenerative” appearance and is associated with amyloid beta plaques in the br

Updated on: May 18,2024

Immune cells in the brain play key role in relationship between gut microbes and b-amyloid deposits

by University of Chicago Medical CenterMicroglia in the brain of male mice with Alzheimer's Disease have a “neurodegenerative” appearance and is associated with amyloid beta plaques in the br

Updated on:May 18,2024

How are 'super agers' protected from Alzheimer's and mental decline?

by Alan Mozes Healthday Reporter(HealthDay)—Some older folks are still sharp as tacks and dementia-free well into their 80s and beyond. Now German researchers have uncovered a possible reason why: The

Updated on: March 13,2024

How are 'super agers' protected from Alzheimer's and mental decline?

by Alan Mozes Healthday Reporter(HealthDay)—Some older folks are still sharp as tacks and dementia-free well into their 80s and beyond. Now German researchers have uncovered a possible reason why: The

Updated on:March 13,2024

Genetic marker that often points to heart disease and Alzheimer's may have fertility benefit

by Arizona State UniversityBen Trumble inside ASU's lab at the School of Human Evolution and Social Change. Credit: Charlie Leight/ASU NewsPrevious research has revealed that the Apolipoprote

Updated on: July 01,2024

Genetic marker that often points to heart disease and Alzheimer's may have fertility benefit

by Arizona State UniversityBen Trumble inside ASU's lab at the School of Human Evolution and Social Change. Credit: Charlie Leight/ASU NewsPrevious research has revealed that the Apolipoprote

Updated on:July 01,2024

Poor gut health may drive multiple sclerosis—better diet may ease it

by Rutgers UniversityDevelopment of colitis in spontaneous EAE mice. (A) Swollen colon in spontaneous EAE mice. (B) H&E histopathology of swollen colon isolated from spontaneous EAE and non-E

Updated on: February 03,2024

Poor gut health may drive multiple sclerosis—better diet may ease it

by Rutgers UniversityDevelopment of colitis in spontaneous EAE mice. (A) Swollen colon in spontaneous EAE mice. (B) H&E histopathology of swollen colon isolated from spontaneous EAE and non-E

Updated on:February 03,2024

Mitochondrial roles in antiviral immunity modify manifestations of neurological diseases

by University of HelsinkiSchematic of antiviral innate immune signaling responses to viral PAMPs. Credit:Nature(2024). DOI: 10.1038/s41586-024-07260-zA multidisciplinary team of scien

Updated on: April 06,2024

Mitochondrial roles in antiviral immunity modify manifestations of neurological diseases

by University of HelsinkiSchematic of antiviral innate immune signaling responses to viral PAMPs. Credit:Nature(2024). DOI: 10.1038/s41586-024-07260-zA multidisciplinary team of scien

Updated on:April 06,2024

The molecular mechanisms of Alzheimer's

by Pacific Northwest National LaboratoryFigure 1 in the paper outlines the quantitative proteomic pipeline for O-GlcNAc analysis. stochastic kinetic simulations (red) and simulations using the co

Updated on: April 07,2024

The molecular mechanisms of Alzheimer's

by Pacific Northwest National LaboratoryFigure 1 in the paper outlines the quantitative proteomic pipeline for O-GlcNAc analysis. stochastic kinetic simulations (red) and simulations using the co

Updated on:April 07,2024

CRISPR helps identify potential Alzheimer's-related protein

by University of TokyoCredit: CC0 Public DomainExperts at the University of Tokyo have identified a new protein in the pathway that leads to Alzheimer's disease. Researchers used the "mo

Updated on: March 30,2024

CRISPR helps identify potential Alzheimer's-related protein

by University of TokyoCredit: CC0 Public DomainExperts at the University of Tokyo have identified a new protein in the pathway that leads to Alzheimer's disease. Researchers used the "mo

Updated on:March 30,2024

Researchers show multiple sclerosis drug can be used as Alzheimer's therapy

by Lindsay Travis,University of KentuckyWorking model for the effect of ponesimod on microglial activation and phagocytosis. Aβ42 binds to TLR4 and induces a complex with S1PR1. S1P co-activates

Updated on: March 02,2024

Researchers show multiple sclerosis drug can be used as Alzheimer's therapy

by Lindsay Travis,University of KentuckyWorking model for the effect of ponesimod on microglial activation and phagocytosis. Aβ42 binds to TLR4 and induces a complex with S1PR1. S1P co-activates

Updated on:March 02,2024

Examining dementia risk in adults with intellectual disability

by Okayama UniversityLittle is known about the risk factors of dementia in people diagnosed with intellectual disabilities. Researchers at Okayama University Hospital, Okayama University, and Asa

Updated on: March 02,2024

Examining dementia risk in adults with intellectual disability

by Okayama UniversityLittle is known about the risk factors of dementia in people diagnosed with intellectual disabilities. Researchers at Okayama University Hospital, Okayama University, and Asa

Updated on:March 02,2024

Leaders in Alzheimer's research herald the dawn of a new era in drug development based on biology of aging

by Alzheimer's Drug Discovery FoundationCredit: Pixabay/CC0 Public DomainA combination of drugs will be needed to effectively treat or prevent Alzheimer's disease and leading experts say we ha

Updated on: April 16,2024

Leaders in Alzheimer's research herald the dawn of a new era in drug development based on biology of aging

by Alzheimer's Drug Discovery FoundationCredit: Pixabay/CC0 Public DomainA combination of drugs will be needed to effectively treat or prevent Alzheimer's disease and leading experts say we ha

Updated on:April 16,2024

Alzheimer's: Blood biomarker may help identify the disease ten years before symptoms start

by Caroline Graff and Charlotte Johansson,The ConversationCredit: AI-generated imageThough Alzheimer's disease affects more than55 million people worldwide, there's still no cure f

Updated on: April 16,2024

Alzheimer's: Blood biomarker may help identify the disease ten years before symptoms start

by Caroline Graff and Charlotte Johansson,The ConversationCredit: AI-generated imageThough Alzheimer's disease affects more than55 million people worldwide, there's still no cure f

Updated on:April 16,2024

New visual technique could advance early detection of neurodegenerative diseases

byUniversity of MinnesotaIntroduction and overview of Cap-QuIC method. Credit:npj Biosensing(2024). DOI: 10.1038/s44328-024-00003-0Researchers at the University of Minnesota have dev

Updated on: August 08,2024

New visual technique could advance early detection of neurodegenerative diseases

byUniversity of MinnesotaIntroduction and overview of Cap-QuIC method. Credit:npj Biosensing(2024). DOI: 10.1038/s44328-024-00003-0Researchers at the University of Minnesota have dev

Updated on:August 08,2024