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Neurology
Focuses on brain health.
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No new drugs for Alzheimer's disease in 15 years

No new drugs for Alzheimer's disease in 15 years

by Vanessa Jane Hall,ScienceNordicCredit: AI-generated imageHow often to you read headlines proclaiming the arrival of a new, ground-breaking treatment for Alzheimer's?The answer is probably

No new drugs for Alzheimer's disease in 15 years

by Vanessa Jane Hall,ScienceNordicCredit: AI-generated imageHow often to you read headlines proclaiming the arrival of a new, ground-breaking treatment for Alzheimer's?The answer is probably
'Anti-tangle' molecule could aid search for new dementia treatments, say scientists

'Anti-tangle' molecule could aid search for new dementia treatments, say scientists

by Vicky Just,University of BathThe solution NMR structure of αS1–25(A) The average structure of αS1–25derived from the 20 lowest-energy structures. Charged (blue: positive, red: negative)

'Anti-tangle' molecule could aid search for new dementia treatments, say scientists

by Vicky Just,University of BathThe solution NMR structure of αS1–25(A) The average structure of αS1–25derived from the 20 lowest-energy structures. Charged (blue: positive, red: negative)
Successful or pathological cognitive aging? The 'frontal preservation, temporal impairment (FPTI)' hypothesis

Successful or pathological cognitive aging? The 'frontal preservation, temporal impairment (FPTI)' hypothesis

by Science China PressThe SCA group has specific frontal preservation and the MCI group has specific temporal impairment on GM morphology, GM network, and WM network properties, in addition, the

Successful or pathological cognitive aging? The 'frontal preservation, temporal impairment (FPTI)' hypothesis

by Science China PressThe SCA group has specific frontal preservation and the MCI group has specific temporal impairment on GM morphology, GM network, and WM network properties, in addition, the
Bodybuilding supplement may help stave off progression of Alzheimer's

Bodybuilding supplement may help stave off progression of Alzheimer's

by Rush University Medical CenterGraphical abstract. Credit:Cell Reports(2023). DOI: 10.1016/j.celrep.2023.112717RUSH researchers recently discovered that a muscle-building supplement

Bodybuilding supplement may help stave off progression of Alzheimer's

by Rush University Medical CenterGraphical abstract. Credit:Cell Reports(2023). DOI: 10.1016/j.celrep.2023.112717RUSH researchers recently discovered that a muscle-building supplement
Neuroprotective mechanism altered by Alzheimer's disease risk genes

Neuroprotective mechanism altered by Alzheimer's disease risk genes

by Molly Chiu,Baylor College of MedicineCredit: Baylor College of MedicineThe brain has a natural protective mechanism against Alzheimer's disease, and researchers at Baylor College of Medic

Neuroprotective mechanism altered by Alzheimer's disease risk genes

by Molly Chiu,Baylor College of MedicineCredit: Baylor College of MedicineThe brain has a natural protective mechanism against Alzheimer's disease, and researchers at Baylor College of Medic
Leaders in Alzheimer's research herald the dawn of a new era in drug development based on biology of aging

Leaders in Alzheimer's research herald the dawn of a new era in drug development based on biology of aging

by Alzheimer's Drug Discovery FoundationCredit: Pixabay/CC0 Public DomainA combination of drugs will be needed to effectively treat or prevent Alzheimer's disease and leading experts say we ha

Leaders in Alzheimer's research herald the dawn of a new era in drug development based on biology of aging

by Alzheimer's Drug Discovery FoundationCredit: Pixabay/CC0 Public DomainA combination of drugs will be needed to effectively treat or prevent Alzheimer's disease and leading experts say we ha
Vascular risk factors and Alzheimer's disease—a new therapeutic opportunity?

Vascular risk factors and Alzheimer's disease—a new therapeutic opportunity?

by IOS PressCurrently, no possibility exists to reliably quantify the risk of Alzheimer's disease (AD) onset in the general population and in subjects with mild cognitive impairment. Metaboli

Vascular risk factors and Alzheimer's disease—a new therapeutic opportunity?

by IOS PressCurrently, no possibility exists to reliably quantify the risk of Alzheimer's disease (AD) onset in the general population and in subjects with mild cognitive impairment. Metaboli
Actively speaking two languages protects against cognitive decline

Actively speaking two languages protects against cognitive decline

by Universitat Pompeu Fabra - BarcelonaCredit: Universitat Pompeu Fabra - BarcelonaIn addition to enabling us to communicate with others, languages are our instrument for conveying our thoughts, ident

Actively speaking two languages protects against cognitive decline

by Universitat Pompeu Fabra - BarcelonaCredit: Universitat Pompeu Fabra - BarcelonaIn addition to enabling us to communicate with others, languages are our instrument for conveying our thoughts, ident
Researchers discover mechanism by which estrogen can trigger fast neuronal responses

Researchers discover mechanism by which estrogen can trigger fast neuronal responses

byBaylor College of MedicineCredit: Public DomainEstrogen, the major female ovarian hormone, can trigger nerve impulses within milliseconds to regulate a variety of physiological processes. At B

Researchers discover mechanism by which estrogen can trigger fast neuronal responses

byBaylor College of MedicineCredit: Public DomainEstrogen, the major female ovarian hormone, can trigger nerve impulses within milliseconds to regulate a variety of physiological processes. At B
Curry spice holds clues to Alzheimer's drug targets

Curry spice holds clues to Alzheimer's drug targets

by Alzheimer's Research UKCalifornian researchers have shed more light on the action of an experimental Alzheimer's drug based on a modified component of the curry spice turmeric. The res

Curry spice holds clues to Alzheimer's drug targets

by Alzheimer's Research UKCalifornian researchers have shed more light on the action of an experimental Alzheimer's drug based on a modified component of the curry spice turmeric. The res
How different areas of the prefrontal cortex influence time variability in individual monkeys

How different areas of the prefrontal cortex influence time variability in individual monkeys

byRIKENDissociations in the involvement of six cortical regions in intra-individual RT variability. Credit:Nature Communications(2024). DOI: 10.1038/s41467-023-44341-5Neuroscientists

How different areas of the prefrontal cortex influence time variability in individual monkeys

byRIKENDissociations in the involvement of six cortical regions in intra-individual RT variability. Credit:Nature Communications(2024). DOI: 10.1038/s41467-023-44341-5Neuroscientists
Researchers show multiple sclerosis drug can be used as Alzheimer's therapy

Researchers show multiple sclerosis drug can be used as Alzheimer's therapy

by Lindsay Travis,University of KentuckyWorking model for the effect of ponesimod on microglial activation and phagocytosis. Aβ42 binds to TLR4 and induces a complex with S1PR1. S1P co-activates

Researchers show multiple sclerosis drug can be used as Alzheimer's therapy

by Lindsay Travis,University of KentuckyWorking model for the effect of ponesimod on microglial activation and phagocytosis. Aβ42 binds to TLR4 and induces a complex with S1PR1. S1P co-activates