FDA advisory panelist outlines issues with aducanumab's approval for Alzheimer's disease

by American College of PhysiciansPET scan of a human brain with Alzheimer's disease. Credit: public domainDespite near unanimous objection from its advisory panel, the U.S. Food and Drug Admi

Updated on: March 30,2024

FDA advisory panelist outlines issues with aducanumab's approval for Alzheimer's disease

by American College of PhysiciansPET scan of a human brain with Alzheimer's disease. Credit: public domainDespite near unanimous objection from its advisory panel, the U.S. Food and Drug Admi

Updated on:March 30,2024

Enzyme treatment of gene may reverse effects of Alzheimer's

by Tel Aviv UniversityFor the last 20 years, researchers have focused on amyloid beta peptides and the "plaque" they sprout in diseased brains as the main target of Alzheimer's rese

Updated on: March 09,2024

Enzyme treatment of gene may reverse effects of Alzheimer's

by Tel Aviv UniversityFor the last 20 years, researchers have focused on amyloid beta peptides and the "plaque" they sprout in diseased brains as the main target of Alzheimer's rese

Updated on:March 09,2024

A promising new approach to data sharing in neuroscience research

byHoward Hughes Medical InstituteOverview of Spyglass. Credit:(2024). DOI: 10.1101/2024.01.25.577295Loren Frank's HHMI lab at UCSF has pioneered an ambitious framework for sharing vast

Updated on: March 28,2024

A promising new approach to data sharing in neuroscience research

byHoward Hughes Medical InstituteOverview of Spyglass. Credit:(2024). DOI: 10.1101/2024.01.25.577295Loren Frank's HHMI lab at UCSF has pioneered an ambitious framework for sharing vast

Updated on:March 28,2024

Blocking inflammation prevents cell death, improves memory in Alzheimer's disease

by University of California, IrvineA brain tissue sample from Kim Green’s study show microglia (red) and plaques (green). Credit: Green lab / UCIUsing a drug compound created to treat cance

Updated on: February 28,2024

Blocking inflammation prevents cell death, improves memory in Alzheimer's disease

by University of California, IrvineA brain tissue sample from Kim Green’s study show microglia (red) and plaques (green). Credit: Green lab / UCIUsing a drug compound created to treat cance

Updated on:February 28,2024

Alzheimer's drug development pipeline: Promising therapies, pharma investment drive momentum in clinical trials

by University of Nevada, Las VegasAgents in clinical trials for treatment of Alzheimer's disease in 2023 (from ClinicalTrials.gov as of the index date of January 1, 2023). The inner ring show

Updated on: April 16,2024

Alzheimer's drug development pipeline: Promising therapies, pharma investment drive momentum in clinical trials

by University of Nevada, Las VegasAgents in clinical trials for treatment of Alzheimer's disease in 2023 (from ClinicalTrials.gov as of the index date of January 1, 2023). The inner ring show

Updated on:April 16,2024

Ultrasound therapy shows promise as a treatment for Alzheimer's disease

by University of QueenslandGraphical representation of the findings of this study: Improved memory, enhanced functional connectivity and an altered proteome were found in APP23 mice in the absenc

Updated on: April 06,2024

Ultrasound therapy shows promise as a treatment for Alzheimer's disease

by University of QueenslandGraphical representation of the findings of this study: Improved memory, enhanced functional connectivity and an altered proteome were found in APP23 mice in the absenc

Updated on:April 06,2024

Chronic musculoskeletal pain may accelerate brain aging

byChinese Academy of SciencesChronic pain leads to accelerated brain aging. Credit: Xie RuiIn a studypublishedinNature Mental Health, scientists from China and the United State

Updated on: March 28,2024

Chronic musculoskeletal pain may accelerate brain aging

byChinese Academy of SciencesChronic pain leads to accelerated brain aging. Credit: Xie RuiIn a studypublishedinNature Mental Health, scientists from China and the United State

Updated on:March 28,2024

MAO is a possible Alzheimer's disease biomarker

by American Chemical SocietyResearchers used mice studies to reveal that MAO activity (yellow) is directly correlated with the progression of Alzheimer's disease and may be used to stage the

Updated on: March 30,2024

MAO is a possible Alzheimer's disease biomarker

by American Chemical SocietyResearchers used mice studies to reveal that MAO activity (yellow) is directly correlated with the progression of Alzheimer's disease and may be used to stage the

Updated on:March 30,2024

Risk for dementia reduced in association with antihypertensive use

by Elana GotkineAntihypertensive use is associated with a reduced risk for dementia compared with untreated hypertension, according to research published online Sept. 12 inJAMA Network Open.Matt

Updated on: March 02,2024

Risk for dementia reduced in association with antihypertensive use

by Elana GotkineAntihypertensive use is associated with a reduced risk for dementia compared with untreated hypertension, according to research published online Sept. 12 inJAMA Network Open.Matt

Updated on:March 02,2024

7T brain scans reveal potential early indicator of Alzheimer's

by Center for BrainHealthCredit: Unsplash/CC0 Public DomainResearchers from the Center for BrainHealth at The University of Texas at Dallas are investigating a potential new early indicator of the dec

Updated on: March 13,2024

7T brain scans reveal potential early indicator of Alzheimer's

by Center for BrainHealthCredit: Unsplash/CC0 Public DomainResearchers from the Center for BrainHealth at The University of Texas at Dallas are investigating a potential new early indicator of the dec

Updated on:March 13,2024

Study reveals key role of TRIO gene in epileptic encephalopathies

byUniversity of MontrealDefective migration of MGE-derived cortical INs inTrio–/–embryos. Credit:Molecular Psychiatry(2024). DOI: 10.1038/s41380-024-02742-yWhat are the m

Updated on: October 09,2024

Study reveals key role of TRIO gene in epileptic encephalopathies

byUniversity of MontrealDefective migration of MGE-derived cortical INs inTrio–/–embryos. Credit:Molecular Psychiatry(2024). DOI: 10.1038/s41380-024-02742-yWhat are the m

Updated on:October 09,2024

Swedish diagnostic method for Alzheimer's becomes international standard

by Krister Svahn,University of GothenburgResearchers at Gothenburg University have developed a reference method for standardized measurements that diagnose Alzheimer's disease decades before

Updated on: February 26,2024

Swedish diagnostic method for Alzheimer's becomes international standard

by Krister Svahn,University of GothenburgResearchers at Gothenburg University have developed a reference method for standardized measurements that diagnose Alzheimer's disease decades before

Updated on:February 26,2024