Central trafficking compartment in neurons malfunctions in majority of Alzheimer's patients

by Columbia University Irving Medical CenterDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.Decades before the first symptoms of Alzheimer's app

Updated on: May 13,2024

Central trafficking compartment in neurons malfunctions in majority of Alzheimer's patients

by Columbia University Irving Medical CenterDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.Decades before the first symptoms of Alzheimer's app

Updated on:May 13,2024

Brain organoids reveal autism biology and potential treatments

byThe Scripps Research InstituteA cerebral organoid showing rosettes (or whirls) of newly developing and migrating new neurons (shown in purplish-red). Credit: Scripps ResearchUsing stem cells g

Updated on: November 07,2024

Brain organoids reveal autism biology and potential treatments

byThe Scripps Research InstituteA cerebral organoid showing rosettes (or whirls) of newly developing and migrating new neurons (shown in purplish-red). Credit: Scripps ResearchUsing stem cells g

Updated on:November 07,2024

A new study shows how neurochemicals affect fMRI readings

byUniversity of North Carolina Health CareStimulus-evoked negative fMRI signals in striatum. Credit: Yen-Yu Ian Shih, Ph.D.The brain is an incredibly complex and active organ that uses electrici

Updated on: March 28,2024

A new study shows how neurochemicals affect fMRI readings

byUniversity of North Carolina Health CareStimulus-evoked negative fMRI signals in striatum. Credit: Yen-Yu Ian Shih, Ph.D.The brain is an incredibly complex and active organ that uses electrici

Updated on:March 28,2024

Tau does not stabilize microtubules, challenges approach to treating Alzheimer's

by Drexel UniversityThis image represents the role of tau and MAP6 in regulating the stable (green) and dynamic (red) parts of a neuron's microtubules. Depleting tau from cultured rat neurons

Updated on: April 02,2024

Tau does not stabilize microtubules, challenges approach to treating Alzheimer's

by Drexel UniversityThis image represents the role of tau and MAP6 in regulating the stable (green) and dynamic (red) parts of a neuron's microtubules. Depleting tau from cultured rat neurons

Updated on:April 02,2024

Study finds brain stores motor memories differently based on decision uncertainty

by National Institute of Information and Communications Technology (NICT)A: Screen of the experiment, B: perturbation pattern. Credit: National Institute of Information and Communications Technology (

Updated on: July 05,2024

Study finds brain stores motor memories differently based on decision uncertainty

by National Institute of Information and Communications Technology (NICT)A: Screen of the experiment, B: perturbation pattern. Credit: National Institute of Information and Communications Technology (

Updated on:July 05,2024

Blocking inflammation prevents cell death, improves memory in Alzheimer's disease

by University of California, IrvineA brain tissue sample from Kim Green’s study show microglia (red) and plaques (green). Credit: Green lab / UCIUsing a drug compound created to treat cance

Updated on: February 28,2024

Blocking inflammation prevents cell death, improves memory in Alzheimer's disease

by University of California, IrvineA brain tissue sample from Kim Green’s study show microglia (red) and plaques (green). Credit: Green lab / UCIUsing a drug compound created to treat cance

Updated on:February 28,2024

Alzheimer's drug development pipeline: Promising therapies, pharma investment drive momentum in clinical trials

by University of Nevada, Las VegasAgents in clinical trials for treatment of Alzheimer's disease in 2023 (from ClinicalTrials.gov as of the index date of January 1, 2023). The inner ring show

Updated on: April 16,2024

Alzheimer's drug development pipeline: Promising therapies, pharma investment drive momentum in clinical trials

by University of Nevada, Las VegasAgents in clinical trials for treatment of Alzheimer's disease in 2023 (from ClinicalTrials.gov as of the index date of January 1, 2023). The inner ring show

Updated on:April 16,2024

Dementia and COVID-19: Determinants of infection and mortality

by IOS PressFactors associated with 60-day mortality in dementia patients infected with SARS-CoV-2. Credit:Journal of Alzheimer's Disease(2022). DOI: 10.3233/JAD-220369The elderly

Updated on: May 06,2024

Dementia and COVID-19: Determinants of infection and mortality

by IOS PressFactors associated with 60-day mortality in dementia patients infected with SARS-CoV-2. Credit:Journal of Alzheimer's Disease(2022). DOI: 10.3233/JAD-220369The elderly

Updated on:May 06,2024

Medical nutrition-drink may affect development of early Alzheimer's

by Karolinska InstitutetIn a new study, an international research team shows that a medical nutrition-drink, consisting of, among other things, essential fatty acids and vitamins, may have an imp

Updated on: March 07,2024

Medical nutrition-drink may affect development of early Alzheimer's

by Karolinska InstitutetIn a new study, an international research team shows that a medical nutrition-drink, consisting of, among other things, essential fatty acids and vitamins, may have an imp

Updated on:March 07,2024

GluN3A knockout mouse: Alternative model for Alzheimer's neurodegeneration

by Emory UniversityGluN3A (in the diagram, NR3) is an inhibitory subunit within NMDA receptor assemblies, which function as glutamate-gated cation channels. GluN3A is a key regulator of neuronal

Updated on: March 30,2024

GluN3A knockout mouse: Alternative model for Alzheimer's neurodegeneration

by Emory UniversityGluN3A (in the diagram, NR3) is an inhibitory subunit within NMDA receptor assemblies, which function as glutamate-gated cation channels. GluN3A is a key regulator of neuronal

Updated on:March 30,2024

Women with Alzheimer's-related gene lose weight more sharply after age 70

by SUNY Downstate Medical CenterResearchers led by Deborah Gustafson, PhD, MS, professor of neurology at SUNY Downstate Medical Center, have shown that women with a gene variant (APOEe4 allele) associ

Updated on: February 26,2024

Women with Alzheimer's-related gene lose weight more sharply after age 70

by SUNY Downstate Medical CenterResearchers led by Deborah Gustafson, PhD, MS, professor of neurology at SUNY Downstate Medical Center, have shown that women with a gene variant (APOEe4 allele) associ

Updated on:February 26,2024

Creating the largest, most comprehensive picture of neural connections to date

byNational Science FoundationThe 50 largest neurons of the adult fruit fly brain connectome. Credit: Tyler Sloan and Amy Sterling for FlyWire, Princeton University, (Dorkenwald et al., 2024)Flip

Updated on: October 16,2024

Creating the largest, most comprehensive picture of neural connections to date

byNational Science FoundationThe 50 largest neurons of the adult fruit fly brain connectome. Credit: Tyler Sloan and Amy Sterling for FlyWire, Princeton University, (Dorkenwald et al., 2024)Flip

Updated on:October 16,2024