Happiness in early adulthood may protect against dementia

by University of California, San FranciscoCredit: Pixabay/CC0 Public DomainWhile research has shown that poor cardiovascular health can damage blood flow to the brain increasing the risk for deme

Updated on: May 06,2024

Happiness in early adulthood may protect against dementia

by University of California, San FranciscoCredit: Pixabay/CC0 Public DomainWhile research has shown that poor cardiovascular health can damage blood flow to the brain increasing the risk for deme

Updated on:May 06,2024

Potential Alzheimer's medication shows promise in mouse model of neurodegenerative disease

by JCI JournalsMemory loss and other cognitive symptoms of Alzheimer's disease are attributed, in part, to the degeneration of acetylcholine-producing neurons. Acetylcholinesterase inhibitors are

Updated on: March 07,2024

Potential Alzheimer's medication shows promise in mouse model of neurodegenerative disease

by JCI JournalsMemory loss and other cognitive symptoms of Alzheimer's disease are attributed, in part, to the degeneration of acetylcholine-producing neurons. Acetylcholinesterase inhibitors are

Updated on:March 07,2024

A 'low dose aspirin' for dementia? Drug ready for first in-human testing

by University of KentuckyLinda Van Eldik in her lab at the Sanders-Brown Center on Aging. Van Eldik's drug candidate, which might function as a sort of "low-dose aspirin" for the pr

Updated on: March 13,2024

A 'low dose aspirin' for dementia? Drug ready for first in-human testing

by University of KentuckyLinda Van Eldik in her lab at the Sanders-Brown Center on Aging. Van Eldik's drug candidate, which might function as a sort of "low-dose aspirin" for the pr

Updated on:March 13,2024

Capturing cortical connectivity close-up

by University of PittsburghCredit: AI-generated imageThe brain is made up of a complex series of networks—signals are constantly bouncing between those networks to allow us to experience the worl

Updated on: February 05,2024

Capturing cortical connectivity close-up

by University of PittsburghCredit: AI-generated imageThe brain is made up of a complex series of networks—signals are constantly bouncing between those networks to allow us to experience the worl

Updated on:February 05,2024

Optical sensors and lab-on-fiber technology may detect Alzheimer's disease at early stages

by Wileya) 3D view of the nanofunctionalized D-shaped lab-on-fiber sensor. b) Related sensing mechanism based on the evaluation of refractive index changes, through evanescent wave interaction, t

Updated on: June 05,2024

Optical sensors and lab-on-fiber technology may detect Alzheimer's disease at early stages

by Wileya) 3D view of the nanofunctionalized D-shaped lab-on-fiber sensor. b) Related sensing mechanism based on the evaluation of refractive index changes, through evanescent wave interaction, t

Updated on:June 05,2024

How does the brain know whether our actions actually make a difference?

by Champalimaud Centre for the UnknownIn "controllable houses", the door's color determines which room it leads to. In contrast, in "uncontrollable houses" the sequence of room

Updated on: February 21,2024

How does the brain know whether our actions actually make a difference?

by Champalimaud Centre for the UnknownIn "controllable houses", the door's color determines which room it leads to. In contrast, in "uncontrollable houses" the sequence of room

Updated on:February 21,2024

Brain 'zips and unzips' information to perform skilled tasks

by University of BirminghamCredit: Pixabay/CC0 Public DomainThe human brain prepares skilled movements such as playing the piano, competing in athletics, or dancing by "zipping and unzipping

Updated on: February 18,2024

Brain 'zips and unzips' information to perform skilled tasks

by University of BirminghamCredit: Pixabay/CC0 Public DomainThe human brain prepares skilled movements such as playing the piano, competing in athletics, or dancing by "zipping and unzipping

Updated on:February 18,2024

Tau-based biomarker tracks Alzheimer's progression

by Washington University School of MedicineKanta Horie, PhD, works with a mass spectrometer that he uses to measure protein levels in cerebrospinal fluid samples. Horie and colleagues at Washingt

Updated on: June 18,2024

Tau-based biomarker tracks Alzheimer's progression

by Washington University School of MedicineKanta Horie, PhD, works with a mass spectrometer that he uses to measure protein levels in cerebrospinal fluid samples. Horie and colleagues at Washingt

Updated on:June 18,2024

Movement disorder ALS and cognitive disorder FTLD show strong molecular overlaps, new study shows

byMassachusetts Institute of TechnologyStained motor cortex tissue from a donor with ALS (right) shows reduced amounts of the protein HLA-E (green) in the vasculature. HLA-E is thought to inhibi

Updated on: March 28,2024

Movement disorder ALS and cognitive disorder FTLD show strong molecular overlaps, new study shows

byMassachusetts Institute of TechnologyStained motor cortex tissue from a donor with ALS (right) shows reduced amounts of the protein HLA-E (green) in the vasculature. HLA-E is thought to inhibi

Updated on:March 28,2024

Tau does not stabilize microtubules, challenges approach to treating Alzheimer's

by Drexel UniversityThis image represents the role of tau and MAP6 in regulating the stable (green) and dynamic (red) parts of a neuron's microtubules. Depleting tau from cultured rat neurons

Updated on: April 02,2024

Tau does not stabilize microtubules, challenges approach to treating Alzheimer's

by Drexel UniversityThis image represents the role of tau and MAP6 in regulating the stable (green) and dynamic (red) parts of a neuron's microtubules. Depleting tau from cultured rat neurons

Updated on:April 02,2024

The power of neighbors: Neighboring synapses shape learning and memory

by Katrin Bühler,University of BaselA mathematical model reveals how interactions between neighboring contact sites of nerve cells influence learning. Credit: University of Basel, BiozentrumA re

Updated on: March 28,2024

The power of neighbors: Neighboring synapses shape learning and memory

by Katrin Bühler,University of BaselA mathematical model reveals how interactions between neighboring contact sites of nerve cells influence learning. Credit: University of Basel, BiozentrumA re

Updated on:March 28,2024

Promising Alzheimer's drug candidate prevents buildup of tau proteins in lab and fruit fly studies

byLancaster UniversityThe brain of a 7-day-old fruit fly with Tau expressed in a neuronal circuit used by the fly in olfactory memory. The green outlines the neurons, which are starting to swell

Updated on: October 21,2024

Promising Alzheimer's drug candidate prevents buildup of tau proteins in lab and fruit fly studies

byLancaster UniversityThe brain of a 7-day-old fruit fly with Tau expressed in a neuronal circuit used by the fly in olfactory memory. The green outlines the neurons, which are starting to swell

Updated on:October 21,2024