Tau does not stabilize microtubules, challenges approach to treating Alzheimer's

by Drexel UniversityThis image represents the role of tau and MAP6 in regulating the stable (green) and dynamic (red) parts of a neuron's microtubules. Depleting tau from cultured rat neurons

Updated on: April 02,2024

Tau does not stabilize microtubules, challenges approach to treating Alzheimer's

by Drexel UniversityThis image represents the role of tau and MAP6 in regulating the stable (green) and dynamic (red) parts of a neuron's microtubules. Depleting tau from cultured rat neurons

Updated on:April 02,2024

Study links premature development of human neurons to brain developmental disorders

byVIB (the Flanders Institute for Biotechnology)Mouse cortex (in blue) transplanted with human neurons (in green). Credit: VIBThe mechanisms underlying intellectual disabilities or autism remain

Updated on: August 08,2024

Study links premature development of human neurons to brain developmental disorders

byVIB (the Flanders Institute for Biotechnology)Mouse cortex (in blue) transplanted with human neurons (in green). Credit: VIBThe mechanisms underlying intellectual disabilities or autism remain

Updated on:August 08,2024

Researchers show multiple sclerosis drug can be used as Alzheimer's therapy

by Lindsay Travis,University of KentuckyWorking model for the effect of ponesimod on microglial activation and phagocytosis. Aβ42 binds to TLR4 and induces a complex with S1PR1. S1P co-activates

Updated on: March 02,2024

Researchers show multiple sclerosis drug can be used as Alzheimer's therapy

by Lindsay Travis,University of KentuckyWorking model for the effect of ponesimod on microglial activation and phagocytosis. Aβ42 binds to TLR4 and induces a complex with S1PR1. S1P co-activates

Updated on:March 02,2024

Brain organoids reveal autism biology and potential treatments

byThe Scripps Research InstituteA cerebral organoid showing rosettes (or whirls) of newly developing and migrating new neurons (shown in purplish-red). Credit: Scripps ResearchUsing stem cells g

Updated on: November 07,2024

Brain organoids reveal autism biology and potential treatments

byThe Scripps Research InstituteA cerebral organoid showing rosettes (or whirls) of newly developing and migrating new neurons (shown in purplish-red). Credit: Scripps ResearchUsing stem cells g

Updated on:November 07,2024

Maintaining heart health may protect against cognitive decline

by American College of CardiologyCredit: CC0 Public DomainPeople with a higher risk of developing cardiovascular disease have increased cognitive decline, including an increase in typical markers

Updated on: April 29,2024

Maintaining heart health may protect against cognitive decline

by American College of CardiologyCredit: CC0 Public DomainPeople with a higher risk of developing cardiovascular disease have increased cognitive decline, including an increase in typical markers

Updated on:April 29,2024

Alzheimer's drug development pipeline: Promising therapies, pharma investment drive momentum in clinical trials

by University of Nevada, Las VegasAgents in clinical trials for treatment of Alzheimer's disease in 2023 (from ClinicalTrials.gov as of the index date of January 1, 2023). The inner ring show

Updated on: April 16,2024

Alzheimer's drug development pipeline: Promising therapies, pharma investment drive momentum in clinical trials

by University of Nevada, Las VegasAgents in clinical trials for treatment of Alzheimer's disease in 2023 (from ClinicalTrials.gov as of the index date of January 1, 2023). The inner ring show

Updated on:April 16,2024

Dementia and COVID-19: Determinants of infection and mortality

by IOS PressFactors associated with 60-day mortality in dementia patients infected with SARS-CoV-2. Credit:Journal of Alzheimer's Disease(2022). DOI: 10.3233/JAD-220369The elderly

Updated on: May 06,2024

Dementia and COVID-19: Determinants of infection and mortality

by IOS PressFactors associated with 60-day mortality in dementia patients infected with SARS-CoV-2. Credit:Journal of Alzheimer's Disease(2022). DOI: 10.3233/JAD-220369The elderly

Updated on:May 06,2024

Medical nutrition-drink may affect development of early Alzheimer's

by Karolinska InstitutetIn a new study, an international research team shows that a medical nutrition-drink, consisting of, among other things, essential fatty acids and vitamins, may have an imp

Updated on: March 07,2024

Medical nutrition-drink may affect development of early Alzheimer's

by Karolinska InstitutetIn a new study, an international research team shows that a medical nutrition-drink, consisting of, among other things, essential fatty acids and vitamins, may have an imp

Updated on:March 07,2024

Large-scale study links dyslexia genetics to brain structure

byMax Planck SocietyCredit: CC0 Public DomainDyslexia is a common learning difficulty in which genes often play a role. How do genes associated with dyslexia relate to brain structure in the gen

Updated on: January 08,2025

Large-scale study links dyslexia genetics to brain structure

byMax Planck SocietyCredit: CC0 Public DomainDyslexia is a common learning difficulty in which genes often play a role. How do genes associated with dyslexia relate to brain structure in the gen

Updated on:January 08,2025

MAO is a possible Alzheimer's disease biomarker

by American Chemical SocietyResearchers used mice studies to reveal that MAO activity (yellow) is directly correlated with the progression of Alzheimer's disease and may be used to stage the

Updated on: March 30,2024

MAO is a possible Alzheimer's disease biomarker

by American Chemical SocietyResearchers used mice studies to reveal that MAO activity (yellow) is directly correlated with the progression of Alzheimer's disease and may be used to stage the

Updated on:March 30,2024

Certain navigational mistakes could be early signs of Alzheimer's disease

by University College LondonCredit: Pixabay/CC0 Public DomainPeople with early Alzheimer's disease have difficulty turning when walking, according to a new study using virtual reality led by

Updated on: March 02,2024

Certain navigational mistakes could be early signs of Alzheimer's disease

by University College LondonCredit: Pixabay/CC0 Public DomainPeople with early Alzheimer's disease have difficulty turning when walking, according to a new study using virtual reality led by

Updated on:March 02,2024

Could there be a link between the enteric neurons, gut microbiome and ALS?

by University of Illinois at ChicagoFigure 1. SOD1G93Amice have slow intestinal mobility, decreased rotarod test time and grip strength during ALS progression. (a) SOD1G93Amice signif

Updated on: February 05,2024

Could there be a link between the enteric neurons, gut microbiome and ALS?

by University of Illinois at ChicagoFigure 1. SOD1G93Amice have slow intestinal mobility, decreased rotarod test time and grip strength during ALS progression. (a) SOD1G93Amice signif

Updated on:February 05,2024