Untangling the role of tau in Alzheimer's disease

by Dani Ellenby, Okinawa Institute of Science and Technology Graduate UniversityWild-type (WT) h-tau loaded in presynaptic terminals inhibited excitatory synaptic transmission. Credit: Tetsuya Hori et

Updated on: July 01,2024

Untangling the role of tau in Alzheimer's disease

by Dani Ellenby, Okinawa Institute of Science and Technology Graduate UniversityWild-type (WT) h-tau loaded in presynaptic terminals inhibited excitatory synaptic transmission. Credit: Tetsuya Hori et

Updated on:July 01,2024

A 'low dose aspirin' for dementia? Drug ready for first in-human testing

by University of KentuckyLinda Van Eldik in her lab at the Sanders-Brown Center on Aging. Van Eldik's drug candidate, which might function as a sort of "low-dose aspirin" for the pr

Updated on: March 13,2024

A 'low dose aspirin' for dementia? Drug ready for first in-human testing

by University of KentuckyLinda Van Eldik in her lab at the Sanders-Brown Center on Aging. Van Eldik's drug candidate, which might function as a sort of "low-dose aspirin" for the pr

Updated on:March 13,2024

Midlife insomnia may increase risk for later dementia

by Lori SolomonInsomnia and short sleep duration in middle age increase the risk for dementia, according to a study published in the September issue ofAge and Ageing.Xiao Tan, from the Zhejiang

Updated on: March 02,2024

Midlife insomnia may increase risk for later dementia

by Lori SolomonInsomnia and short sleep duration in middle age increase the risk for dementia, according to a study published in the September issue ofAge and Ageing.Xiao Tan, from the Zhejiang

Updated on:March 02,2024

Prediction of conversion to Alzheimer's disease with longitudinal measures and time-to-event data

by IOS PressPredicting the timing of Alzheimer's disease (AD) conversion for individuals with mild cognitive impairment (MCI) can be significantly improved by incorporating longitudinal chang

Updated on: March 07,2024

Prediction of conversion to Alzheimer's disease with longitudinal measures and time-to-event data

by IOS PressPredicting the timing of Alzheimer's disease (AD) conversion for individuals with mild cognitive impairment (MCI) can be significantly improved by incorporating longitudinal chang

Updated on:March 07,2024

Novel method facilitates study of oxidized lipids involved in neurodegenerative diseases

NOVEMBER 15, 2023byFAPESPGraphical abstract. Credit:Free Radical Biology and Medicine(2023). DOI: 10.1016/j.freeradbiomed.2023.08.019Lipids are a diversified class of biomolecules wi

Updated on: March 28,2024

Novel method facilitates study of oxidized lipids involved in neurodegenerative diseases

NOVEMBER 15, 2023byFAPESPGraphical abstract. Credit:Free Radical Biology and Medicine(2023). DOI: 10.1016/j.freeradbiomed.2023.08.019Lipids are a diversified class of biomolecules wi

Updated on:March 28,2024

When memory loss should concern you

by Lauren Woods,University of ConnecticutCredit: AI-generated imageAlthough there is currently no cure for Alzheimer's Disease, Dr. Patrick Coll of UConn's Center on Aging recommends ear

Updated on: February 27,2024

When memory loss should concern you

by Lauren Woods,University of ConnecticutCredit: AI-generated imageAlthough there is currently no cure for Alzheimer's Disease, Dr. Patrick Coll of UConn's Center on Aging recommends ear

Updated on:February 27,2024

Allopurinol may cut risk for neurodegenerative diseases

by Elana GotkineXanthine dehydrogenase/oxidase blockers may reduce the risk for neurodegenerative diseases, according to a study published online May 17 inPLOS ONE.Yizhe Song, from the Washingto

Updated on: February 05,2024

Allopurinol may cut risk for neurodegenerative diseases

by Elana GotkineXanthine dehydrogenase/oxidase blockers may reduce the risk for neurodegenerative diseases, according to a study published online May 17 inPLOS ONE.Yizhe Song, from the Washingto

Updated on:February 05,2024

Enzyme treatment of gene may reverse effects of Alzheimer's

by Tel Aviv UniversityFor the last 20 years, researchers have focused on amyloid beta peptides and the "plaque" they sprout in diseased brains as the main target of Alzheimer's rese

Updated on: March 09,2024

Enzyme treatment of gene may reverse effects of Alzheimer's

by Tel Aviv UniversityFor the last 20 years, researchers have focused on amyloid beta peptides and the "plaque" they sprout in diseased brains as the main target of Alzheimer's rese

Updated on:March 09,2024

LATE: A common but largely unknown cause of dementia

by Andrew E. Budson,Harvard UniversityCredit: Pixabay/CC0 Public DomainIf dementia is a general term that means thinking and memory has deteriorated to the point that it interferes with day-to-d

Updated on: May 11,2024

LATE: A common but largely unknown cause of dementia

by Andrew E. Budson,Harvard UniversityCredit: Pixabay/CC0 Public DomainIf dementia is a general term that means thinking and memory has deteriorated to the point that it interferes with day-to-d

Updated on:May 11,2024

Common degenerative brain disease may begin to develop already in middle age

byUniversity of HelsinkiImmunohistochemical staining with 5G4 antibody against alpha-synuclein in the Tampere Sudden Death Study cohort. Black arrowheads highlight LBs and gray arrowheads point

Updated on: March 28,2024

Common degenerative brain disease may begin to develop already in middle age

byUniversity of HelsinkiImmunohistochemical staining with 5G4 antibody against alpha-synuclein in the Tampere Sudden Death Study cohort. Black arrowheads highlight LBs and gray arrowheads point

Updated on:March 28,2024

Further evidence shows education reduces risk of Alzheimer's

by CORDISCredit: CC0 Public DomainNew research from Cambridge University, supported by European Union funding, has added weight to the theory that education protects against Alzheimer's disea

Updated on: July 01,2024

Further evidence shows education reduces risk of Alzheimer's

by CORDISCredit: CC0 Public DomainNew research from Cambridge University, supported by European Union funding, has added weight to the theory that education protects against Alzheimer's disea

Updated on:July 01,2024

Could 'zombie cells' in the skin be aging your brain too?

by Mayo Clinic News NetworkCredit: Pixabay/CC0 Public DomainMayo Clinic researchers have found that senescent cells—non-dividing "zombie" cells—accumulate in the skin as people age and may i

Updated on: November 06,2024

Could 'zombie cells' in the skin be aging your brain too?

by Mayo Clinic News NetworkCredit: Pixabay/CC0 Public DomainMayo Clinic researchers have found that senescent cells—non-dividing "zombie" cells—accumulate in the skin as people age and may i

Updated on:November 06,2024