Unraveling the mysteries of the presynapse with super resolution microscopy

by Queensland Brain Institutea Graphical representation of the Dual-pulse sub-diffractional Tracking of Internalized Molecules (DsdTIM) protocol. b Representative epifluorescence image of an axonal se

Updated on: March 28,2024

Unraveling the mysteries of the presynapse with super resolution microscopy

by Queensland Brain Institutea Graphical representation of the Dual-pulse sub-diffractional Tracking of Internalized Molecules (DsdTIM) protocol. b Representative epifluorescence image of an axonal se

Updated on:March 28,2024

FDA advisory panelist outlines issues with aducanumab's approval for Alzheimer's disease

by American College of PhysiciansPET scan of a human brain with Alzheimer's disease. Credit: public domainDespite near unanimous objection from its advisory panel, the U.S. Food and Drug Admi

Updated on: March 30,2024

FDA advisory panelist outlines issues with aducanumab's approval for Alzheimer's disease

by American College of PhysiciansPET scan of a human brain with Alzheimer's disease. Credit: public domainDespite near unanimous objection from its advisory panel, the U.S. Food and Drug Admi

Updated on:March 30,2024

Multivariate analysis improves on cognitive testing in Alzheimer's disease

by Future Science GroupMultivariate analysis of cognitive tests in Alzheimer's disease identifies five distinct groups of Alzheimer's disease patients, and suggests that multivitamins might sl

Updated on: March 07,2024

Multivariate analysis improves on cognitive testing in Alzheimer's disease

by Future Science GroupMultivariate analysis of cognitive tests in Alzheimer's disease identifies five distinct groups of Alzheimer's disease patients, and suggests that multivitamins might sl

Updated on:March 07,2024

Women with Alzheimer's-related gene lose weight more sharply after age 70

by SUNY Downstate Medical CenterResearchers led by Deborah Gustafson, PhD, MS, professor of neurology at SUNY Downstate Medical Center, have shown that women with a gene variant (APOEe4 allele) associ

Updated on: February 26,2024

Women with Alzheimer's-related gene lose weight more sharply after age 70

by SUNY Downstate Medical CenterResearchers led by Deborah Gustafson, PhD, MS, professor of neurology at SUNY Downstate Medical Center, have shown that women with a gene variant (APOEe4 allele) associ

Updated on:February 26,2024

Most seniors with dementia live at home, despite pain, anxiety, poor health

by University of California, San FranciscoCredit: CC0 Public DomainContrary to popular belief, most older Americans with advancing dementia remain in their own homes—many until they die. But a ne

Updated on: May 13,2024

Most seniors with dementia live at home, despite pain, anxiety, poor health

by University of California, San FranciscoCredit: CC0 Public DomainContrary to popular belief, most older Americans with advancing dementia remain in their own homes—many until they die. But a ne

Updated on:May 13,2024

Creating the largest, most comprehensive picture of neural connections to date

byNational Science FoundationThe 50 largest neurons of the adult fruit fly brain connectome. Credit: Tyler Sloan and Amy Sterling for FlyWire, Princeton University, (Dorkenwald et al., 2024)Flip

Updated on: October 16,2024

Creating the largest, most comprehensive picture of neural connections to date

byNational Science FoundationThe 50 largest neurons of the adult fruit fly brain connectome. Credit: Tyler Sloan and Amy Sterling for FlyWire, Princeton University, (Dorkenwald et al., 2024)Flip

Updated on:October 16,2024

Movement disorder ALS and cognitive disorder FTLD show strong molecular overlaps, new study shows

byMassachusetts Institute of TechnologyStained motor cortex tissue from a donor with ALS (right) shows reduced amounts of the protein HLA-E (green) in the vasculature. HLA-E is thought to inhibi

Updated on: March 28,2024

Movement disorder ALS and cognitive disorder FTLD show strong molecular overlaps, new study shows

byMassachusetts Institute of TechnologyStained motor cortex tissue from a donor with ALS (right) shows reduced amounts of the protein HLA-E (green) in the vasculature. HLA-E is thought to inhibi

Updated on:March 28,2024

Prediction of conversion to Alzheimer's disease with longitudinal measures and time-to-event data

by IOS PressPredicting the timing of Alzheimer's disease (AD) conversion for individuals with mild cognitive impairment (MCI) can be significantly improved by incorporating longitudinal chang

Updated on: March 07,2024

Prediction of conversion to Alzheimer's disease with longitudinal measures and time-to-event data

by IOS PressPredicting the timing of Alzheimer's disease (AD) conversion for individuals with mild cognitive impairment (MCI) can be significantly improved by incorporating longitudinal chang

Updated on:March 07,2024

Immune booster drugs meant to kill tumors found to improve Alzheimer's symptoms in mice

by Bob Yirka , Medical XpressCredit: martha sexton/public domain(MedicalXpress)—A team of researchers working at the Weizmann Institute of Science in Israel has found that a type of drug meant to help

Updated on: February 27,2024

Immune booster drugs meant to kill tumors found to improve Alzheimer's symptoms in mice

by Bob Yirka , Medical XpressCredit: martha sexton/public domain(MedicalXpress)—A team of researchers working at the Weizmann Institute of Science in Israel has found that a type of drug meant to help

Updated on:February 27,2024

Dementia deaths rise during the summer of COVID, leading to concern

by Laurie Archbald-Pannone,The ConversationCredit: Unsplash/CC0 Public DomainDeaths from dementia during the summer of 2020 are nearly20% higherthan the number of dementia-related de

Updated on: March 19,2024

Dementia deaths rise during the summer of COVID, leading to concern

by Laurie Archbald-Pannone,The ConversationCredit: Unsplash/CC0 Public DomainDeaths from dementia during the summer of 2020 are nearly20% higherthan the number of dementia-related de

Updated on:March 19,2024

Could 'zombie cells' in the skin be aging your brain too?

by Mayo Clinic News NetworkCredit: Pixabay/CC0 Public DomainMayo Clinic researchers have found that senescent cells—non-dividing "zombie" cells—accumulate in the skin as people age and may i

Updated on: November 06,2024

Could 'zombie cells' in the skin be aging your brain too?

by Mayo Clinic News NetworkCredit: Pixabay/CC0 Public DomainMayo Clinic researchers have found that senescent cells—non-dividing "zombie" cells—accumulate in the skin as people age and may i

Updated on:November 06,2024

Combining cell therapy with approved drug shows promise for treating multiple sclerosis

byJosep Carreras Leukaemia Research InstituteCredit: Pixabay/CC0 Public DomainMultiple sclerosis (MS) is a long-term disease where the immune system mistakenly attacks the protective layer aroun

Updated on: October 14,2024

Combining cell therapy with approved drug shows promise for treating multiple sclerosis

byJosep Carreras Leukaemia Research InstituteCredit: Pixabay/CC0 Public DomainMultiple sclerosis (MS) is a long-term disease where the immune system mistakenly attacks the protective layer aroun

Updated on:October 14,2024