A promising discovery in a rare neurodegenerative disease

by Katherine Gombay,McGill UniversityGene expression changes in SCA6 cerebellum at disease onset. (a) Timeline of disease progression in SCA6 mouse model. (b) Cerebellar vermis tissue was extrac

Updated on: March 30,2024

A promising discovery in a rare neurodegenerative disease

by Katherine Gombay,McGill UniversityGene expression changes in SCA6 cerebellum at disease onset. (a) Timeline of disease progression in SCA6 mouse model. (b) Cerebellar vermis tissue was extrac

Updated on:March 30,2024

Allopurinol may cut risk for neurodegenerative diseases

by Elana GotkineXanthine dehydrogenase/oxidase blockers may reduce the risk for neurodegenerative diseases, according to a study published online May 17 inPLOS ONE.Yizhe Song, from the Washingto

Updated on: February 05,2024

Allopurinol may cut risk for neurodegenerative diseases

by Elana GotkineXanthine dehydrogenase/oxidase blockers may reduce the risk for neurodegenerative diseases, according to a study published online May 17 inPLOS ONE.Yizhe Song, from the Washingto

Updated on:February 05,2024

Alzheimer's disease and type 2 diabetes—hope for inhibitors against amyloid plaques

by Technical University MunichA new class of designed macrocyclic peptides has been developed which are highly potent inhibitors of amyloid plaque formation. Credit: Kapurniotu/ TUMEffective ther

Updated on: April 08,2024

Alzheimer's disease and type 2 diabetes—hope for inhibitors against amyloid plaques

by Technical University MunichA new class of designed macrocyclic peptides has been developed which are highly potent inhibitors of amyloid plaque formation. Credit: Kapurniotu/ TUMEffective ther

Updated on:April 08,2024

New discovery could help treat a rare and severe form of amyloidosis

byWileyPET scan of a human brain with Alzheimer's disease. Credit: public domainIn people with a rare condition called light chain amyloidosis, light chain proteins—which are a component of

Updated on: July 11,2024

New discovery could help treat a rare and severe form of amyloidosis

byWileyPET scan of a human brain with Alzheimer's disease. Credit: public domainIn people with a rare condition called light chain amyloidosis, light chain proteins—which are a component of

Updated on:July 11,2024

MRI's may be initial window into CTE diagnosis in living; approach may shave years off diagnosis

by Boston University School of MedicineCredit: Pixabay/CC0 Public DomainWhile chronic traumatic encephalopathy (CTE) cannot yet be diagnosed during life, a new study provides the best evidence to

Updated on: April 01,2024

MRI's may be initial window into CTE diagnosis in living; approach may shave years off diagnosis

by Boston University School of MedicineCredit: Pixabay/CC0 Public DomainWhile chronic traumatic encephalopathy (CTE) cannot yet be diagnosed during life, a new study provides the best evidence to

Updated on:April 01,2024

Alzheimer's risk gene impairs development of new neurons in mice

by Society for NeuroscienceApoE-expressing astrocytes (green) interacting with tdTomato-expressing dendrites (red) from adult newborn hippocampal neurons. Credit: Tensaouti et al.,eNeuro&nb

Updated on: April 20,2024

Alzheimer's risk gene impairs development of new neurons in mice

by Society for NeuroscienceApoE-expressing astrocytes (green) interacting with tdTomato-expressing dendrites (red) from adult newborn hippocampal neurons. Credit: Tensaouti et al.,eNeuro&nb

Updated on:April 20,2024

Clinicians should address needs of family caregivers of persons with dementia

by University of Pennsylvania School of NursingMore than 15 million family members and other unpaid caregivers provide care to persons living with dementia in the United States. Yet the current h

Updated on: March 07,2024

Clinicians should address needs of family caregivers of persons with dementia

by University of Pennsylvania School of NursingMore than 15 million family members and other unpaid caregivers provide care to persons living with dementia in the United States. Yet the current h

Updated on:March 07,2024

FDA advisory panelist outlines issues with aducanumab's approval for Alzheimer's disease

by American College of PhysiciansPET scan of a human brain with Alzheimer's disease. Credit: public domainDespite near unanimous objection from its advisory panel, the U.S. Food and Drug Admi

Updated on: March 30,2024

FDA advisory panelist outlines issues with aducanumab's approval for Alzheimer's disease

by American College of PhysiciansPET scan of a human brain with Alzheimer's disease. Credit: public domainDespite near unanimous objection from its advisory panel, the U.S. Food and Drug Admi

Updated on:March 30,2024

Both high and low HDL cholesterol tied to increased risk of dementia

by American Academy of NeurologyCredit: CC0 Public DomainHaving either high or low levels of high-density lipoprotein (HDL) cholesterol, or "good" cholesterol, is tied to a small increa

Updated on: March 02,2024

Both high and low HDL cholesterol tied to increased risk of dementia

by American Academy of NeurologyCredit: CC0 Public DomainHaving either high or low levels of high-density lipoprotein (HDL) cholesterol, or "good" cholesterol, is tied to a small increa

Updated on:March 02,2024

Arterial stiffening linked to Alzheimer's disease

by Paul Govern,Vanderbilt UniversityCredit: Pixabay/CC0 Public DomainA research team from Vanderbilt University Medical Center reports inNeurologythat greater stiffening of the aorta

Updated on: May 22,2024

Arterial stiffening linked to Alzheimer's disease

by Paul Govern,Vanderbilt UniversityCredit: Pixabay/CC0 Public DomainA research team from Vanderbilt University Medical Center reports inNeurologythat greater stiffening of the aorta

Updated on:May 22,2024

Study investigates how effective multiple sclerosis medications are across racial and ethnic groups

byAmerican Academy of NeurologyCredit: Unsplash/CC0 Public DomainFor people with relapsing-remitting multiple sclerosis (MS), a new study has found that the drug ofatumumab is more effective tha

Updated on: July 31,2024

Study investigates how effective multiple sclerosis medications are across racial and ethnic groups

byAmerican Academy of NeurologyCredit: Unsplash/CC0 Public DomainFor people with relapsing-remitting multiple sclerosis (MS), a new study has found that the drug ofatumumab is more effective tha

Updated on:July 31,2024

AEDs tied to higher pneumonia risk in Alzheimer patients

(HealthDay)—Antiepileptic drug (AED) use may increase the risk for pneumonia in patients with Alzheimer disease (AD), according to a study recently published in theJournal of Alzheimer's Dis

Updated on: March 19,2024

AEDs tied to higher pneumonia risk in Alzheimer patients

(HealthDay)—Antiepileptic drug (AED) use may increase the risk for pneumonia in patients with Alzheimer disease (AD), according to a study recently published in theJournal of Alzheimer's Dis

Updated on:March 19,2024