Alzheimer's disease and type 2 diabetes—hope for inhibitors against amyloid plaques

by Technical University MunichA new class of designed macrocyclic peptides has been developed which are highly potent inhibitors of amyloid plaque formation. Credit: Kapurniotu/ TUMEffective ther

Updated on: April 08,2024

Alzheimer's disease and type 2 diabetes—hope for inhibitors against amyloid plaques

by Technical University MunichA new class of designed macrocyclic peptides has been developed which are highly potent inhibitors of amyloid plaque formation. Credit: Kapurniotu/ TUMEffective ther

Updated on:April 08,2024

Novel method facilitates study of oxidized lipids involved in neurodegenerative diseases

NOVEMBER 15, 2023byFAPESPGraphical abstract. Credit:Free Radical Biology and Medicine(2023). DOI: 10.1016/j.freeradbiomed.2023.08.019Lipids are a diversified class of biomolecules wi

Updated on: March 28,2024

Novel method facilitates study of oxidized lipids involved in neurodegenerative diseases

NOVEMBER 15, 2023byFAPESPGraphical abstract. Credit:Free Radical Biology and Medicine(2023). DOI: 10.1016/j.freeradbiomed.2023.08.019Lipids are a diversified class of biomolecules wi

Updated on:March 28,2024

Discovery adds context to Alzheimer's fight

by Paul Mayne,University of Western OntarioRobarts Research Institute scientists Vania and Marco Prado have found a gene, TRPM2, that could be a therapeutic target to assist in decreasing cognit

Updated on: February 27,2024

Discovery adds context to Alzheimer's fight

by Paul Mayne,University of Western OntarioRobarts Research Institute scientists Vania and Marco Prado have found a gene, TRPM2, that could be a therapeutic target to assist in decreasing cognit

Updated on:February 27,2024

Largescale brain epigenetics study provides new insights into dementia

by University of ExeterCredit: Unsplash/CC0 Public DomainThe largest study of its kind has unveiled new insights into how genes are regulated in dementia, including discovering 84 new genes linke

Updated on: May 13,2024

Largescale brain epigenetics study provides new insights into dementia

by University of ExeterCredit: Unsplash/CC0 Public DomainThe largest study of its kind has unveiled new insights into how genes are regulated in dementia, including discovering 84 new genes linke

Updated on:May 13,2024

LATE: A common but largely unknown cause of dementia

by Andrew E. Budson,Harvard UniversityCredit: Pixabay/CC0 Public DomainIf dementia is a general term that means thinking and memory has deteriorated to the point that it interferes with day-to-d

Updated on: May 11,2024

LATE: A common but largely unknown cause of dementia

by Andrew E. Budson,Harvard UniversityCredit: Pixabay/CC0 Public DomainIf dementia is a general term that means thinking and memory has deteriorated to the point that it interferes with day-to-d

Updated on:May 11,2024

Untangling the role of tau in Alzheimer's disease

by Dani Ellenby, Okinawa Institute of Science and Technology Graduate UniversityWild-type (WT) h-tau loaded in presynaptic terminals inhibited excitatory synaptic transmission. Credit: Tetsuya Hori et

Updated on: July 01,2024

Untangling the role of tau in Alzheimer's disease

by Dani Ellenby, Okinawa Institute of Science and Technology Graduate UniversityWild-type (WT) h-tau loaded in presynaptic terminals inhibited excitatory synaptic transmission. Credit: Tetsuya Hori et

Updated on:July 01,2024

Researchers identify genetic factors that contribute to Alzheimer's disease

by Boston University School of MedicineResearchers have identified several new genes responsible for Alzheimer's disease (AD) including those leading to functional and structural changes in t

Updated on: March 07,2024

Researchers identify genetic factors that contribute to Alzheimer's disease

by Boston University School of MedicineResearchers have identified several new genes responsible for Alzheimer's disease (AD) including those leading to functional and structural changes in t

Updated on:March 07,2024

Multivariate analysis improves on cognitive testing in Alzheimer's disease

by Future Science GroupMultivariate analysis of cognitive tests in Alzheimer's disease identifies five distinct groups of Alzheimer's disease patients, and suggests that multivitamins might sl

Updated on: March 07,2024

Multivariate analysis improves on cognitive testing in Alzheimer's disease

by Future Science GroupMultivariate analysis of cognitive tests in Alzheimer's disease identifies five distinct groups of Alzheimer's disease patients, and suggests that multivitamins might sl

Updated on:March 07,2024

Alzheimer's disease and the holidays

by Graciela Gutierrez,Baylor College of MedicineCredit: Unsplash/CC0 Public DomainThe holidays can be a special time, but may present challenges for those with dementia and their loved ones. Tra

Updated on: March 19,2024

Alzheimer's disease and the holidays

by Graciela Gutierrez,Baylor College of MedicineCredit: Unsplash/CC0 Public DomainThe holidays can be a special time, but may present challenges for those with dementia and their loved ones. Tra

Updated on:March 19,2024

Allopurinol may cut risk for neurodegenerative diseases

by Elana GotkineXanthine dehydrogenase/oxidase blockers may reduce the risk for neurodegenerative diseases, according to a study published online May 17 inPLOS ONE.Yizhe Song, from the Washingto

Updated on: February 05,2024

Allopurinol may cut risk for neurodegenerative diseases

by Elana GotkineXanthine dehydrogenase/oxidase blockers may reduce the risk for neurodegenerative diseases, according to a study published online May 17 inPLOS ONE.Yizhe Song, from the Washingto

Updated on:February 05,2024

Education, intelligence may protect cognition, but don't prevent Alzheimer's disease

by Johns Hopkins University School of MedicinePet scan. Credit: Rebecca GottesmanIn a search for clues to what may delay or prevent Alzheimer's disease, Johns Hopkins Medicine scientists repo

Updated on: June 24,2024

Education, intelligence may protect cognition, but don't prevent Alzheimer's disease

by Johns Hopkins University School of MedicinePet scan. Credit: Rebecca GottesmanIn a search for clues to what may delay or prevent Alzheimer's disease, Johns Hopkins Medicine scientists repo

Updated on:June 24,2024

Movement disorder ALS and cognitive disorder FTLD show strong molecular overlaps, new study shows

byMassachusetts Institute of TechnologyStained motor cortex tissue from a donor with ALS (right) shows reduced amounts of the protein HLA-E (green) in the vasculature. HLA-E is thought to inhibi

Updated on: March 28,2024

Movement disorder ALS and cognitive disorder FTLD show strong molecular overlaps, new study shows

byMassachusetts Institute of TechnologyStained motor cortex tissue from a donor with ALS (right) shows reduced amounts of the protein HLA-E (green) in the vasculature. HLA-E is thought to inhibi

Updated on:March 28,2024