Prediction of conversion to Alzheimer's disease with longitudinal measures and time-to-event data

by IOS PressPredicting the timing of Alzheimer's disease (AD) conversion for individuals with mild cognitive impairment (MCI) can be significantly improved by incorporating longitudinal chang

Updated on: March 07,2024

Prediction of conversion to Alzheimer's disease with longitudinal measures and time-to-event data

by IOS PressPredicting the timing of Alzheimer's disease (AD) conversion for individuals with mild cognitive impairment (MCI) can be significantly improved by incorporating longitudinal chang

Updated on:March 07,2024

Early lead exposure could result in memory issues later in life

Updated on: September 02,2025

Early lead exposure could result in memory issues later in life

Updated on:September 02,2025

New discovery could help treat a rare and severe form of amyloidosis

byWileyPET scan of a human brain with Alzheimer's disease. Credit: public domainIn people with a rare condition called light chain amyloidosis, light chain proteins—which are a component of

Updated on: July 11,2024

New discovery could help treat a rare and severe form of amyloidosis

byWileyPET scan of a human brain with Alzheimer's disease. Credit: public domainIn people with a rare condition called light chain amyloidosis, light chain proteins—which are a component of

Updated on:July 11,2024

Risk for dementia reduced in association with antihypertensive use

by Elana GotkineAntihypertensive use is associated with a reduced risk for dementia compared with untreated hypertension, according to research published online Sept. 12 inJAMA Network Open.Matt

Updated on: March 02,2024

Risk for dementia reduced in association with antihypertensive use

by Elana GotkineAntihypertensive use is associated with a reduced risk for dementia compared with untreated hypertension, according to research published online Sept. 12 inJAMA Network Open.Matt

Updated on:March 02,2024

Experimental drug targeting Alzheimer's disease shows anti-aging effects

by Salk InstituteAs mice age, those treated with J147 (right) showed improved physiology, memory and appearance that more closely resembled younger mice. Credit: Salk Institute for Biological Stu

Updated on: February 27,2024

Experimental drug targeting Alzheimer's disease shows anti-aging effects

by Salk InstituteAs mice age, those treated with J147 (right) showed improved physiology, memory and appearance that more closely resembled younger mice. Credit: Salk Institute for Biological Stu

Updated on:February 27,2024

Biogen reanalyzes studies, presses ahead on Alzheimer's drug

by Marilynn MarchioneIn this Aug. 14, 2018 file photo, Dr. William Burke goes over a PET brain scan at Banner Alzheimers Institute in Phoenix. The drug company Biogen Inc. says it will seek federal ap

Updated on: April 25,2024

Biogen reanalyzes studies, presses ahead on Alzheimer's drug

by Marilynn MarchioneIn this Aug. 14, 2018 file photo, Dr. William Burke goes over a PET brain scan at Banner Alzheimers Institute in Phoenix. The drug company Biogen Inc. says it will seek federal ap

Updated on:April 25,2024

A recurrent neural network-based framework to non-linearly model behaviorally relevant neural dynamics

by Ingrid Fadelli , Medical XpressDPAD overview. Credit: Sani, Pesaran & Shanechi.A key objective of several neuroscience studies is to understand and model how the dynamics of distinct population

Updated on: October 16,2024

A recurrent neural network-based framework to non-linearly model behaviorally relevant neural dynamics

by Ingrid Fadelli , Medical XpressDPAD overview. Credit: Sani, Pesaran & Shanechi.A key objective of several neuroscience studies is to understand and model how the dynamics of distinct population

Updated on:October 16,2024

Movement disorder ALS and cognitive disorder FTLD show strong molecular overlaps, new study shows

byMassachusetts Institute of TechnologyStained motor cortex tissue from a donor with ALS (right) shows reduced amounts of the protein HLA-E (green) in the vasculature. HLA-E is thought to inhibi

Updated on: March 28,2024

Movement disorder ALS and cognitive disorder FTLD show strong molecular overlaps, new study shows

byMassachusetts Institute of TechnologyStained motor cortex tissue from a donor with ALS (right) shows reduced amounts of the protein HLA-E (green) in the vasculature. HLA-E is thought to inhibi

Updated on:March 28,2024

Alzheimer's genetics point to new research direction

by Robyn Mills,University of AdelaideDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.A University of Adelaide analysis of genetic mutations which c

Updated on: April 16,2024

Alzheimer's genetics point to new research direction

by Robyn Mills,University of AdelaideDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.A University of Adelaide analysis of genetic mutations which c

Updated on:April 16,2024

People living with dementia add voice to care model debate

by Flinders UniversityCredit: CC0 Public DomainCoinciding with Dementia Awareness Month, a new Flinders University study has asked Australian aged-care residents to rate the quality of care they

Updated on: May 08,2024

People living with dementia add voice to care model debate

by Flinders UniversityCredit: CC0 Public DomainCoinciding with Dementia Awareness Month, a new Flinders University study has asked Australian aged-care residents to rate the quality of care they

Updated on:May 08,2024

Unraveling the mysteries of the presynapse with super resolution microscopy

by Queensland Brain Institutea Graphical representation of the Dual-pulse sub-diffractional Tracking of Internalized Molecules (DsdTIM) protocol. b Representative epifluorescence image of an axonal se

Updated on: March 28,2024

Unraveling the mysteries of the presynapse with super resolution microscopy

by Queensland Brain Institutea Graphical representation of the Dual-pulse sub-diffractional Tracking of Internalized Molecules (DsdTIM) protocol. b Representative epifluorescence image of an axonal se

Updated on:March 28,2024

FDA advisory panelist outlines issues with aducanumab's approval for Alzheimer's disease

by American College of PhysiciansPET scan of a human brain with Alzheimer's disease. Credit: public domainDespite near unanimous objection from its advisory panel, the U.S. Food and Drug Admi

Updated on: March 30,2024

FDA advisory panelist outlines issues with aducanumab's approval for Alzheimer's disease

by American College of PhysiciansPET scan of a human brain with Alzheimer's disease. Credit: public domainDespite near unanimous objection from its advisory panel, the U.S. Food and Drug Admi

Updated on:March 30,2024