Optogenetics approach reveals how alcohol use disorder impairs cognitive flexibility

by Danielle Michaud,Texas A&M UniversityExcessive alcohol intake reduces thalamically evoked burst-pause response in DMS CINs and impairs reversal of operant conditioning. Credit:Scien

Updated on: January 15,2025

Optogenetics approach reveals how alcohol use disorder impairs cognitive flexibility

by Danielle Michaud,Texas A&M UniversityExcessive alcohol intake reduces thalamically evoked burst-pause response in DMS CINs and impairs reversal of operant conditioning. Credit:Scien

Updated on:January 15,2025

Scientists say Alzheimer's is probably a collection of diseases that should be classified and treated separately

by Hebrew University of JerusalemDeciphering the mechanism that underlies the development of Alzheimer's disease in certain families but not in others, researchers at the Hebrew University of

Updated on: February 26,2024

Scientists say Alzheimer's is probably a collection of diseases that should be classified and treated separately

by Hebrew University of JerusalemDeciphering the mechanism that underlies the development of Alzheimer's disease in certain families but not in others, researchers at the Hebrew University of

Updated on:February 26,2024

Alzheimer's disease can be diagnosed before symptoms emerge

by Lund UniversityNIA-AA versus IWG criteria. Differences in the nomenclature of cognitively unimpaired individuals with (+) or without (−) in vivo biomarker evidence of Aβ (A) and tau (T) pathol

Updated on: April 10,2024

Alzheimer's disease can be diagnosed before symptoms emerge

by Lund UniversityNIA-AA versus IWG criteria. Differences in the nomenclature of cognitively unimpaired individuals with (+) or without (−) in vivo biomarker evidence of Aβ (A) and tau (T) pathol

Updated on:April 10,2024

The power of neighbors: Neighboring synapses shape learning and memory

by Katrin Bühler,University of BaselA mathematical model reveals how interactions between neighboring contact sites of nerve cells influence learning. Credit: University of Basel, BiozentrumA re

Updated on: March 28,2024

The power of neighbors: Neighboring synapses shape learning and memory

by Katrin Bühler,University of BaselA mathematical model reveals how interactions between neighboring contact sites of nerve cells influence learning. Credit: University of Basel, BiozentrumA re

Updated on:March 28,2024

Alzheimer's research—intracellular calcium store malfunction leads to brain hyperactivity

by Universitaet TübingenAmyloid proteins (plaques, blue) in the cerebral cortex of a mouse model of Alzheimer’s disease, surrounded by cortical immune cells (microglia, green). Activated microgli

Updated on: April 16,2024

Alzheimer's research—intracellular calcium store malfunction leads to brain hyperactivity

by Universitaet TübingenAmyloid proteins (plaques, blue) in the cerebral cortex of a mouse model of Alzheimer’s disease, surrounded by cortical immune cells (microglia, green). Activated microgli

Updated on:April 16,2024

Dementia and COVID-19: Determinants of infection and mortality

by IOS PressFactors associated with 60-day mortality in dementia patients infected with SARS-CoV-2. Credit:Journal of Alzheimer's Disease(2022). DOI: 10.3233/JAD-220369The elderly

Updated on: May 06,2024

Dementia and COVID-19: Determinants of infection and mortality

by IOS PressFactors associated with 60-day mortality in dementia patients infected with SARS-CoV-2. Credit:Journal of Alzheimer's Disease(2022). DOI: 10.3233/JAD-220369The elderly

Updated on:May 06,2024

Prediction of conversion to Alzheimer's disease with longitudinal measures and time-to-event data

by IOS PressPredicting the timing of Alzheimer's disease (AD) conversion for individuals with mild cognitive impairment (MCI) can be significantly improved by incorporating longitudinal chang

Updated on: March 07,2024

Prediction of conversion to Alzheimer's disease with longitudinal measures and time-to-event data

by IOS PressPredicting the timing of Alzheimer's disease (AD) conversion for individuals with mild cognitive impairment (MCI) can be significantly improved by incorporating longitudinal chang

Updated on:March 07,2024

Dementia healthcare must adapt to tackle global dementia crisis

by King's College LondonA new report from Alzheimer's Disease International, authored by researchers at King's College London and the London School of Economics and Political Science

Updated on: March 09,2024

Dementia healthcare must adapt to tackle global dementia crisis

by King's College LondonA new report from Alzheimer's Disease International, authored by researchers at King's College London and the London School of Economics and Political Science

Updated on:March 09,2024

People with cluster headaches may have a significantly increased risk of other illnesses

by American Academy of NeurologyCredit: CC0 Public DomainPeople with cluster headaches may be more than three times more likely to have other medical conditions such as heart disease, mental diso

Updated on: February 18,2024

People with cluster headaches may have a significantly increased risk of other illnesses

by American Academy of NeurologyCredit: CC0 Public DomainPeople with cluster headaches may be more than three times more likely to have other medical conditions such as heart disease, mental diso

Updated on:February 18,2024

A 'low dose aspirin' for dementia? Drug ready for first in-human testing

by University of KentuckyLinda Van Eldik in her lab at the Sanders-Brown Center on Aging. Van Eldik's drug candidate, which might function as a sort of "low-dose aspirin" for the pr

Updated on: March 13,2024

A 'low dose aspirin' for dementia? Drug ready for first in-human testing

by University of KentuckyLinda Van Eldik in her lab at the Sanders-Brown Center on Aging. Van Eldik's drug candidate, which might function as a sort of "low-dose aspirin" for the pr

Updated on:March 13,2024

Alzheimer's disease and the holidays

by Graciela Gutierrez,Baylor College of MedicineCredit: Unsplash/CC0 Public DomainThe holidays can be a special time, but may present challenges for those with dementia and their loved ones. Tra

Updated on: March 19,2024

Alzheimer's disease and the holidays

by Graciela Gutierrez,Baylor College of MedicineCredit: Unsplash/CC0 Public DomainThe holidays can be a special time, but may present challenges for those with dementia and their loved ones. Tra

Updated on:March 19,2024

Constant tinnitus is linked to altered brain activity

by Karolinska InstitutetGraphical absract. Credit: DOI: 10.1172/JCI155094There has to date been no reliable objective method of diagnosing tinnitus. Researchers from Karolinska Institutet now sho

Updated on: February 05,2024

Constant tinnitus is linked to altered brain activity

by Karolinska InstitutetGraphical absract. Credit: DOI: 10.1172/JCI155094There has to date been no reliable objective method of diagnosing tinnitus. Researchers from Karolinska Institutet now sho

Updated on:February 05,2024