Reimagining preclinical trials: Marmosets as model systems for the study of Alzheimer's disease

by University of PittsburghMarmoset models bridge the current translation gap between human studies and cell and rodent models of AD. Establishment of marmoset models of aging and genetic risk lo

Updated on: March 02,2024 20

Reimagining preclinical trials: Marmosets as model systems for the study of Alzheimer's disease

by University of PittsburghMarmoset models bridge the current translation gap between human studies and cell and rodent models of AD. Establishment of marmoset models of aging and genetic risk lo

Updated on:March 02,2024 20

Immune booster drugs meant to kill tumors found to improve Alzheimer's symptoms in mice

by Bob Yirka , Medical XpressCredit: martha sexton/public domain(MedicalXpress)—A team of researchers working at the Weizmann Institute of Science in Israel has found that a type of drug meant to help

Updated on: February 27,2024 16

Immune booster drugs meant to kill tumors found to improve Alzheimer's symptoms in mice

by Bob Yirka , Medical XpressCredit: martha sexton/public domain(MedicalXpress)—A team of researchers working at the Weizmann Institute of Science in Israel has found that a type of drug meant to help

Updated on:February 27,2024 16

Study hints at ways to generate new neurons in old brains

byStanford University Medical CenterCredit: CC0 Public DomainMost neurons in the human brain last a lifetime, and for good reason. Intricate, long-term information is preserved in the complex st

Updated on: October 18,2024 0

Study hints at ways to generate new neurons in old brains

byStanford University Medical CenterCredit: CC0 Public DomainMost neurons in the human brain last a lifetime, and for good reason. Intricate, long-term information is preserved in the complex st

Updated on:October 18,2024 0

Alzheimer's research—intracellular calcium store malfunction leads to brain hyperactivity

by Universitaet TübingenAmyloid proteins (plaques, blue) in the cerebral cortex of a mouse model of Alzheimer’s disease, surrounded by cortical immune cells (microglia, green). Activated microgli

Updated on: April 16,2024 15

Alzheimer's research—intracellular calcium store malfunction leads to brain hyperactivity

by Universitaet TübingenAmyloid proteins (plaques, blue) in the cerebral cortex of a mouse model of Alzheimer’s disease, surrounded by cortical immune cells (microglia, green). Activated microgli

Updated on:April 16,2024 15

Early accumulation of tau in the brain predicts memory decline in Alzheimer's disease

by Karolinska InstitutetHigh accumulation of tau in the brain measured by a PET scanner was the only biomarker that could predict cognitive decline in healthy individuals, people with mild cognit

Updated on: May 18,2024 4

Early accumulation of tau in the brain predicts memory decline in Alzheimer's disease

by Karolinska InstitutetHigh accumulation of tau in the brain measured by a PET scanner was the only biomarker that could predict cognitive decline in healthy individuals, people with mild cognit

Updated on:May 18,2024 4

Possible pathway to new therapy for Alzheimer's disease

by Boston University School of MedicineResearchers have uncovered an enzyme and a biochemical pathway they believe may lead to the identification of drugs that could inhibit the production of bet

Updated on: March 07,2024 19

Possible pathway to new therapy for Alzheimer's disease

by Boston University School of MedicineResearchers have uncovered an enzyme and a biochemical pathway they believe may lead to the identification of drugs that could inhibit the production of bet

Updated on:March 07,2024 19

Researchers create a new window on leading genetic cause of Alzheimer's

by Pacific Northwest National LaboratoryWorkflow for molecular characterization of CSF-Lps.Lipoproteins are exchange labeled with a rhodamine-containing phospholipid and size distribution determi

Updated on: March 02,2024 12

Researchers create a new window on leading genetic cause of Alzheimer's

by Pacific Northwest National LaboratoryWorkflow for molecular characterization of CSF-Lps.Lipoproteins are exchange labeled with a rhodamine-containing phospholipid and size distribution determi

Updated on:March 02,2024 12

Alzheimer's detected before symptoms via new eye technology

by Association for Research in Vision and OphthalmologyRockville, Md. Scientists may have overcome a major roadblock in the development of Alzheimer's therapies by creating a new technology t

Updated on: March 07,2024 18

Alzheimer's detected before symptoms via new eye technology

by Association for Research in Vision and OphthalmologyRockville, Md. Scientists may have overcome a major roadblock in the development of Alzheimer's therapies by creating a new technology t

Updated on:March 07,2024 18

The role of verb fluency in the detection of early cognitive impairment in Alzheimer's disease

by IOS PressVerb fluency score. Credit: Memory Clinic and Research Center of Fundació ACE, Institut Català de Neurociències Aplicades, Barcelona, SpainThe ability to generate spoken verbs in infi

Updated on: March 09,2024 11

The role of verb fluency in the detection of early cognitive impairment in Alzheimer's disease

by IOS PressVerb fluency score. Credit: Memory Clinic and Research Center of Fundació ACE, Institut Català de Neurociències Aplicades, Barcelona, SpainThe ability to generate spoken verbs in infi

Updated on:March 09,2024 11

A participatory research project tackling Alzheimer's disease

by Egle Marija Ramanauskaite,Public Library of ScienceCredit: Human Computation Institute CC-BY-NC-SA 4.0, Graphic by PachecoDesignlab.comEarlier this year, weintroducedyou to WeCure

Updated on: February 28,2024 15

A participatory research project tackling Alzheimer's disease

by Egle Marija Ramanauskaite,Public Library of ScienceCredit: Human Computation Institute CC-BY-NC-SA 4.0, Graphic by PachecoDesignlab.comEarlier this year, weintroducedyou to WeCure

Updated on:February 28,2024 15

Navigation skill test could diagnose Alzheimer's long before memory fails

by Gerry Everding,Washington University School of Medicine in St. LouisThe hippocampus (shown in red) is associated with cognitive mapping skills. Credit: Life Science Databases via Wikimedia Co

Updated on: February 28,2024 19

Navigation skill test could diagnose Alzheimer's long before memory fails

by Gerry Everding,Washington University School of Medicine in St. LouisThe hippocampus (shown in red) is associated with cognitive mapping skills. Credit: Life Science Databases via Wikimedia Co

Updated on:February 28,2024 19

Direct oral anticoagulants reduce dementia risk in Asian AFib patients compared to traditional blood thinners: Study

by American College of CardiologyCredit: Pixabay/CC0 Public DomainThe use of direct oral anticoagulants (DOACs) was associated with a reduction in dementia risk compared to traditional blood thin

Updated on: March 02,2024 12

Direct oral anticoagulants reduce dementia risk in Asian AFib patients compared to traditional blood thinners: Study

by American College of CardiologyCredit: Pixabay/CC0 Public DomainThe use of direct oral anticoagulants (DOACs) was associated with a reduction in dementia risk compared to traditional blood thin

Updated on:March 02,2024 12