Discovery of cilia defects in ALS patients suggests new treatment path

byVIB (the Flanders Institute for Biotechnology)Motor neurons with damaged primary cilia (green) from patients with the C21orf2 mutation. Credit: VIBAmyotrophic lateral sclerosis (ALS) is a deva

Updated on: January 15,2025

Discovery of cilia defects in ALS patients suggests new treatment path

byVIB (the Flanders Institute for Biotechnology)Motor neurons with damaged primary cilia (green) from patients with the C21orf2 mutation. Credit: VIBAmyotrophic lateral sclerosis (ALS) is a deva

Updated on:January 15,2025

How zebrafish map their environment: Spatial orientation mechanisms surprisingly similar to our own

by Sophia Jahns, Max Planck Institute for Biological CyberneticsIdentification of PCs in the larval zebrafish brain. Credit:Nature(2024). DOI: 10.1038/s41586-024-07867-2Researchers are tur

Updated on: September 06,2024

How zebrafish map their environment: Spatial orientation mechanisms surprisingly similar to our own

by Sophia Jahns, Max Planck Institute for Biological CyberneticsIdentification of PCs in the larval zebrafish brain. Credit:Nature(2024). DOI: 10.1038/s41586-024-07867-2Researchers are tur

Updated on:September 06,2024

Cells from human umbilical cord blood improve cognition in Alzheimer's disease model mice

by Cell Transplantation Center of Excellence for Aging and Brain RepairAlzheimer's disease (AD), which affects an estimated 26 million people worldwide, is the fourth leading cause of death a

Updated on: February 26,2024

Cells from human umbilical cord blood improve cognition in Alzheimer's disease model mice

by Cell Transplantation Center of Excellence for Aging and Brain RepairAlzheimer's disease (AD), which affects an estimated 26 million people worldwide, is the fourth leading cause of death a

Updated on:February 26,2024

Modulation of brain cholesterol: A new line of research in Alzheimer's disease treatment?

by Institut National de la Sante et de la Recherche MedicaleFluorescent labelling of the Tau protein in a hNT human cell. Credit: ©Inserm/U837We have known for some years that Alzheimer&#39

Updated on: February 26,2024

Modulation of brain cholesterol: A new line of research in Alzheimer's disease treatment?

by Institut National de la Sante et de la Recherche MedicaleFluorescent labelling of the Tau protein in a hNT human cell. Credit: ©Inserm/U837We have known for some years that Alzheimer&#39

Updated on:February 26,2024

Team reports major breakthrough in understanding Alzheimer's disease

by Trinity College DublinA human donor Alzheimer's disease brain tissue stained with an agent called 'congo-red', which allows for the visualization of amyloid-beta plaques (red) in t

Updated on: February 26,2024

Team reports major breakthrough in understanding Alzheimer's disease

by Trinity College DublinA human donor Alzheimer's disease brain tissue stained with an agent called 'congo-red', which allows for the visualization of amyloid-beta plaques (red) in t

Updated on:February 26,2024

Minimally invasive neural interface allows brain access without skull opening

byRice UniversityEndocisternal neural interface in human and sheep models. Credit:Nature Biomedical Engineering(2024). DOI: 10.1038/s41551-024-01281-9A team of researchers led by Ric

Updated on: November 28,2024

Minimally invasive neural interface allows brain access without skull opening

byRice UniversityEndocisternal neural interface in human and sheep models. Credit:Nature Biomedical Engineering(2024). DOI: 10.1038/s41551-024-01281-9A team of researchers led by Ric

Updated on:November 28,2024

AI decodes whole-cortex functional images to predict behavioral states

byKobe UniversityA new "end-to-end" deep learning method for the prediction of behavioral states uses whole-cortex functional imaging that do not require preprocessing or pre-specified

Updated on: March 28,2024

AI decodes whole-cortex functional images to predict behavioral states

byKobe UniversityA new "end-to-end" deep learning method for the prediction of behavioral states uses whole-cortex functional imaging that do not require preprocessing or pre-specified

Updated on:March 28,2024

Unlocking Alzheimer's mysteries: A comprehensive brain connectome-based survey

by TranSpreadStructural connectivity (SC) refers to anatomical links and is usually estimated using fiber bundles derived from diffusion MRI; Functional connectivity (FC) and effective connectivity (E

Updated on: March 28,2024

Unlocking Alzheimer's mysteries: A comprehensive brain connectome-based survey

by TranSpreadStructural connectivity (SC) refers to anatomical links and is usually estimated using fiber bundles derived from diffusion MRI; Functional connectivity (FC) and effective connectivity (E

Updated on:March 28,2024

Key mechanisms in asymptomatic Alzheimer's disease brains offer potential protection against cognitive decline

byIndiana UniversityMicroglia and astrocytic coverage around compact, intermediate, and filamentous amyloid plaques between AD and AsymAD cases. Credit:Acta Neuropathologica(2024). D

Updated on: October 21,2024

Key mechanisms in asymptomatic Alzheimer's disease brains offer potential protection against cognitive decline

byIndiana UniversityMicroglia and astrocytic coverage around compact, intermediate, and filamentous amyloid plaques between AD and AsymAD cases. Credit:Acta Neuropathologica(2024). D

Updated on:October 21,2024

Depression and dementia in the age of COVID-19

by Donald Weaver,The ConversationMore than half of patients with dementia also suffer from depression. If the depression remains untreated, the associated memory and cognitive problems worsen. C

Updated on: March 30,2024

Depression and dementia in the age of COVID-19

by Donald Weaver,The ConversationMore than half of patients with dementia also suffer from depression. If the depression remains untreated, the associated memory and cognitive problems worsen. C

Updated on:March 30,2024

Simple molecular reagents to treat Alzheimer's disease

by The Korea Advanced Institute of Science and Technology (KAIST)Overview of a rational strategy for designing compact aromatic molecules with multiple reactivities against pathological factors f

Updated on: June 20,2024

Simple molecular reagents to treat Alzheimer's disease

by The Korea Advanced Institute of Science and Technology (KAIST)Overview of a rational strategy for designing compact aromatic molecules with multiple reactivities against pathological factors f

Updated on:June 20,2024

Long-term use of opioid patches common among persons with Alzheimer's disease

by University of Eastern FinlandApproximately seven per cent of persons with Alzheimer's disease use strong pain medicines, opioids, for non-cancer pain for a period longer than six months, a

Updated on: March 07,2024

Long-term use of opioid patches common among persons with Alzheimer's disease

by University of Eastern FinlandApproximately seven per cent of persons with Alzheimer's disease use strong pain medicines, opioids, for non-cancer pain for a period longer than six months, a

Updated on:March 07,2024