Reimagining preclinical trials: Marmosets as model systems for the study of Alzheimer's disease

by University of PittsburghMarmoset models bridge the current translation gap between human studies and cell and rodent models of AD. Establishment of marmoset models of aging and genetic risk lo

Updated on: March 02,2024

Reimagining preclinical trials: Marmosets as model systems for the study of Alzheimer's disease

by University of PittsburghMarmoset models bridge the current translation gap between human studies and cell and rodent models of AD. Establishment of marmoset models of aging and genetic risk lo

Updated on:March 02,2024

Neuroscientists find that animals replay incidentally encoded episodic memories

byIndiana UniversityGraphical abstract. Credit:Current Biology(2024). DOI: 10.1016/j.cub.2023.12.043Indiana University neuroscientists have found the first evidence that rodents can

Updated on: March 13,2024

Neuroscientists find that animals replay incidentally encoded episodic memories

byIndiana UniversityGraphical abstract. Credit:Current Biology(2024). DOI: 10.1016/j.cub.2023.12.043Indiana University neuroscientists have found the first evidence that rodents can

Updated on:March 13,2024

Dysfunctional endosomes are early sign of neurodegeneration

by University of California - San DiegoFalse-colored scanning electron micrograph of a human neuron. Credit: Image courtesy of Thomas Deerinck, NCMIR, UC San Diego.Writing in the April 11 issue o

Updated on: February 28,2024

Dysfunctional endosomes are early sign of neurodegeneration

by University of California - San DiegoFalse-colored scanning electron micrograph of a human neuron. Credit: Image courtesy of Thomas Deerinck, NCMIR, UC San Diego.Writing in the April 11 issue o

Updated on:February 28,2024

Study reports on contributions to white matter injury in Alzheimer's disease

by Impact Journals LLCA vicious cycle generating WM injury driven by mixed vascular and ADNC in the aging human white matter. Diagnostic challenges for IHC and neuroimaging. Credit:Aging(2

Updated on: March 02,2024

Study reports on contributions to white matter injury in Alzheimer's disease

by Impact Journals LLCA vicious cycle generating WM injury driven by mixed vascular and ADNC in the aging human white matter. Diagnostic challenges for IHC and neuroimaging. Credit:Aging(2

Updated on:March 02,2024

Study says Alzheimer's plaques can also affect the brain's blood vessels

by Bob Shepard,University of Alabama at Birmingham3-D microscope image of blood vessels (in red) with surrounding vascular amyloid plaques (in green). Credit: Ian KimbroughAmyloid beta, the plaq

Updated on: February 27,2024

Study says Alzheimer's plaques can also affect the brain's blood vessels

by Bob Shepard,University of Alabama at Birmingham3-D microscope image of blood vessels (in red) with surrounding vascular amyloid plaques (in green). Credit: Ian KimbroughAmyloid beta, the plaq

Updated on:February 27,2024

Innovative AI solution to classify epileptic seizures

by Carnegie Mellon Portugal ProgramExamples of detection and crop, when the bed and the patient were properly detected, surrounding scenery removed, with enough space left to capture the full scale of

Updated on: February 05,2024

Innovative AI solution to classify epileptic seizures

by Carnegie Mellon Portugal ProgramExamples of detection and crop, when the bed and the patient were properly detected, surrounding scenery removed, with enough space left to capture the full scale of

Updated on:February 05,2024

Mouse study finds sex-based differences in how brains handle threats

Mouse study finds sex-based differences in how brains handle threatsby Claire Loewen,McGill UniversityMales and females similarly acquire threat discrimination. Credit:Nature Neuroscience&

Updated on: September 23,2024

Mouse study finds sex-based differences in how brains handle threats

Mouse study finds sex-based differences in how brains handle threatsby Claire Loewen,McGill UniversityMales and females similarly acquire threat discrimination. Credit:Nature Neuroscience&

Updated on:September 23,2024

PNA5 protein shows potential for treating Parkinson's-related cognitive decline and dementia

byUniversity of ArizonaPNA5 blunts neuronal cell loss in the hippocampus. Credit:Experimental Neurology(2024). DOI: 10.1016/j.expneurol.2024.114926A recently published study by resea

Updated on: November 28,2024

PNA5 protein shows potential for treating Parkinson's-related cognitive decline and dementia

byUniversity of ArizonaPNA5 blunts neuronal cell loss in the hippocampus. Credit:Experimental Neurology(2024). DOI: 10.1016/j.expneurol.2024.114926A recently published study by resea

Updated on:November 28,2024

Imaging technique shows Alzheimer's disease progress

by Wiebe Van Der Veen,University of TwenteThe high-lighted squares (left) are the 30 by 30 micron areas in the middle and right images (upper: plaque, lower: tangle). Credit: Univers

Updated on: May 06,2024

Imaging technique shows Alzheimer's disease progress

by Wiebe Van Der Veen,University of TwenteThe high-lighted squares (left) are the 30 by 30 micron areas in the middle and right images (upper: plaque, lower: tangle). Credit: Univers

Updated on:May 06,2024

Occupational complexity linked to better cognitive performance after damage to the brain's white matter

by Alzheimer's Research UKResearchers in the US have presented findings indicating that individuals who have a history of complex occupations, involving work with other people, are better abl

Updated on: March 07,2024

Occupational complexity linked to better cognitive performance after damage to the brain's white matter

by Alzheimer's Research UKResearchers in the US have presented findings indicating that individuals who have a history of complex occupations, involving work with other people, are better abl

Updated on:March 07,2024

New study reveals how biological sex influences brain proteins and disease risk

by Emory UniversitySummary of main analyses. Credit:Nature Medicine(2023). DOI:10.1038/s41591-023-02509-yAn Emory led study published inNature MedicineandSynapse&nbs

Updated on: March 02,2024

New study reveals how biological sex influences brain proteins and disease risk

by Emory UniversitySummary of main analyses. Credit:Nature Medicine(2023). DOI:10.1038/s41591-023-02509-yAn Emory led study published inNature MedicineandSynapse&nbs

Updated on:March 02,2024

Alzheimer's-disease-related proteases control axonal guidance by regulating growth cone dynamics

by VIB (the Flanders Institute for Biotechnology)Diagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.BACE1 is the major drug target for Alzheimer's

Updated on: February 26,2024

Alzheimer's-disease-related proteases control axonal guidance by regulating growth cone dynamics

by VIB (the Flanders Institute for Biotechnology)Diagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.BACE1 is the major drug target for Alzheimer's

Updated on:February 26,2024