Study reveals the possibility of curbing synapse loss in Alzheimer's

by Children's Hospital BostonThis schematic shows how beta-amyloid (Aß) oligomers, the classical complement cascade and microglia work together to induce synapse loss in the pre-plaque Alzhei

Updated on: February 28,2024

Study reveals the possibility of curbing synapse loss in Alzheimer's

by Children's Hospital BostonThis schematic shows how beta-amyloid (Aß) oligomers, the classical complement cascade and microglia work together to induce synapse loss in the pre-plaque Alzhei

Updated on:February 28,2024

Alzheimer's research—intracellular calcium store malfunction leads to brain hyperactivity

by Universitaet TübingenAmyloid proteins (plaques, blue) in the cerebral cortex of a mouse model of Alzheimer’s disease, surrounded by cortical immune cells (microglia, green). Activated microgli

Updated on: April 16,2024

Alzheimer's research—intracellular calcium store malfunction leads to brain hyperactivity

by Universitaet TübingenAmyloid proteins (plaques, blue) in the cerebral cortex of a mouse model of Alzheimer’s disease, surrounded by cortical immune cells (microglia, green). Activated microgli

Updated on:April 16,2024

'Lesser of two evils' argument used to defend antipsychotic overuse for dementia

by University of ReadingCredit: University of ReadingThe increasing use of antipsychotic drugs to manage dementia in care homes has been explained by some practitioners as "the lesser of two

Updated on: March 09,2024

'Lesser of two evils' argument used to defend antipsychotic overuse for dementia

by University of ReadingCredit: University of ReadingThe increasing use of antipsychotic drugs to manage dementia in care homes has been explained by some practitioners as "the lesser of two

Updated on:March 09,2024

AI decodes whole-cortex functional images to predict behavioral states

byKobe UniversityA new "end-to-end" deep learning method for the prediction of behavioral states uses whole-cortex functional imaging that do not require preprocessing or pre-specified

Updated on: March 28,2024

AI decodes whole-cortex functional images to predict behavioral states

byKobe UniversityA new "end-to-end" deep learning method for the prediction of behavioral states uses whole-cortex functional imaging that do not require preprocessing or pre-specified

Updated on:March 28,2024

Investigational Alzheimer's drug improves biomarkers of the disease

by Washington University School of MedicineRandall Bateman, MD, director of the Dominantly Inherited Alzheimer Network-Trials Unit (DIAN-TU), an ongoing international clinical trial to evaluate e

Updated on: April 16,2024

Investigational Alzheimer's drug improves biomarkers of the disease

by Washington University School of MedicineRandall Bateman, MD, director of the Dominantly Inherited Alzheimer Network-Trials Unit (DIAN-TU), an ongoing international clinical trial to evaluate e

Updated on:April 16,2024

Flotillin is a novel diagnostic blood marker of Alzheimer's disease

by Nagoya City UniversityFlotillin in serum collected from patients with AD and non-AD cases was examined by western blot analysis. Intensity of flotillin bands was quantified using Image J. A, The re

Updated on: March 30,2024

Flotillin is a novel diagnostic blood marker of Alzheimer's disease

by Nagoya City UniversityFlotillin in serum collected from patients with AD and non-AD cases was examined by western blot analysis. Intensity of flotillin bands was quantified using Image J. A, The re

Updated on:March 30,2024

Alzheimer's patients are more often hospitalized after initiating antibiotic use

by University of Eastern FinlandCredit: CC0 Public DomainPeople with Alzheimer's disease (AD) are more often hospitalized after antibiotic initiation than people without AD, a new study from

Updated on: March 09,2024

Alzheimer's patients are more often hospitalized after initiating antibiotic use

by University of Eastern FinlandCredit: CC0 Public DomainPeople with Alzheimer's disease (AD) are more often hospitalized after antibiotic initiation than people without AD, a new study from

Updated on:March 09,2024

How an Alzheimer's-related protein forms plaques

by Leiden UniversityCredit: Leiden UniversityNeurological diseases such as Alzheimer's disease are characterised by aggregates of protein in the brain. The connection of these aggregates to t

Updated on: March 09,2024

How an Alzheimer's-related protein forms plaques

by Leiden UniversityCredit: Leiden UniversityNeurological diseases such as Alzheimer's disease are characterised by aggregates of protein in the brain. The connection of these aggregates to t

Updated on:March 09,2024

The role of verb fluency in the detection of early cognitive impairment in Alzheimer's disease

by IOS PressVerb fluency score. Credit: Memory Clinic and Research Center of Fundació ACE, Institut Català de Neurociències Aplicades, Barcelona, SpainThe ability to generate spoken verbs in infi

Updated on: March 09,2024

The role of verb fluency in the detection of early cognitive impairment in Alzheimer's disease

by IOS PressVerb fluency score. Credit: Memory Clinic and Research Center of Fundació ACE, Institut Català de Neurociències Aplicades, Barcelona, SpainThe ability to generate spoken verbs in infi

Updated on:March 09,2024

Midlife diet could help you eat your way to a healthy brain

by Deakin UniversityCredit: Wikipedia.People who eat a healthy diet during middle age have a larger brain volume than those with less healthy diets, new research reveals, suggesting food choices

Updated on: March 09,2024

Midlife diet could help you eat your way to a healthy brain

by Deakin UniversityCredit: Wikipedia.People who eat a healthy diet during middle age have a larger brain volume than those with less healthy diets, new research reveals, suggesting food choices

Updated on:March 09,2024

A healthy lifestyle almost halves the risk of dementia in people with type 2 diabetes

by DiabetologiaCredit: Unsplash/CC0 Public DomainA healthy lifestyle reduces the risk of dementia in those with type 2 diabetes (T2D), according to a study of hundreds of thousands of people in t

Updated on: June 24,2024

A healthy lifestyle almost halves the risk of dementia in people with type 2 diabetes

by DiabetologiaCredit: Unsplash/CC0 Public DomainA healthy lifestyle reduces the risk of dementia in those with type 2 diabetes (T2D), according to a study of hundreds of thousands of people in t

Updated on:June 24,2024

Mitochondrial DNA fragment losses predict Parkinson's disease before symptoms appear

byUniversity of BarcelonaImage of a fibroblast from a patient with Parkinson's disease. Mitochondria are shown in green and fragments of damaged mitochondria in red. Some of these fragments

Updated on: March 28,2024

Mitochondrial DNA fragment losses predict Parkinson's disease before symptoms appear

byUniversity of BarcelonaImage of a fibroblast from a patient with Parkinson's disease. Mitochondria are shown in green and fragments of damaged mitochondria in red. Some of these fragments

Updated on:March 28,2024