Researchers identify the 'broken gate' causing unstoppable brain signals in severe childhood epilepsy

by Florey Institute of Neuroscience and Mental Health2D transmembrane topology of the wild-type (WT) Nav1.2 channel showing 27 domains DI−DIV and amino acid residues N1662 (cytosolic side of S5DIV) an

Updated on: August 03,2024

Researchers identify the 'broken gate' causing unstoppable brain signals in severe childhood epilepsy

by Florey Institute of Neuroscience and Mental Health2D transmembrane topology of the wild-type (WT) Nav1.2 channel showing 27 domains DI−DIV and amino acid residues N1662 (cytosolic side of S5DIV) an

Updated on:August 03,2024

How a tangled protein kills brain cells, promotes Alzheimer's

by Lisa Marshall,University of Colorado at BoulderGraphical abstract. Credit:Neuron(2021). DOI: 10.1016/j.neuron.2021.03.026Look deep inside the brain of someone with Alzheimer's

Updated on: July 04,2024

How a tangled protein kills brain cells, promotes Alzheimer's

by Lisa Marshall,University of Colorado at BoulderGraphical abstract. Credit:Neuron(2021). DOI: 10.1016/j.neuron.2021.03.026Look deep inside the brain of someone with Alzheimer's

Updated on:July 04,2024

Dietary interventions can improve memory performance for diseases like Alzheimer's

by CORDISDietary supplementation could play a crucial role in keeping Europe's ageing population healthy, an EU-funded study has confirmed. The LIPIDIDIET project, which was completed in Marc

Updated on: February 26,2024

Dietary interventions can improve memory performance for diseases like Alzheimer's

by CORDISDietary supplementation could play a crucial role in keeping Europe's ageing population healthy, an EU-funded study has confirmed. The LIPIDIDIET project, which was completed in Marc

Updated on:February 26,2024

Global effort to map the human brain releases first data

byAllen Institute for Brain ScienceBrain slice being prepared for analysis and study. Credit: Erik Dinnel / Allen InstituteThe BRAIN Initiative Cell Atlas Network (BICAN) has launched its first

Updated on: October 16,2024

Global effort to map the human brain releases first data

byAllen Institute for Brain ScienceBrain slice being prepared for analysis and study. Credit: Erik Dinnel / Allen InstituteThe BRAIN Initiative Cell Atlas Network (BICAN) has launched its first

Updated on:October 16,2024

Landmark editorial identifies microbes as major cause of Alzheimer's disease

by Joe Paxton,University of ManchesterDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.A worldwide team of senior scientists and clinicians have com

Updated on: February 28,2024

Landmark editorial identifies microbes as major cause of Alzheimer's disease

by Joe Paxton,University of ManchesterDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.A worldwide team of senior scientists and clinicians have com

Updated on:February 28,2024

Mitochondrial DNA fragment losses predict Parkinson's disease before symptoms appear

byUniversity of BarcelonaImage of a fibroblast from a patient with Parkinson's disease. Mitochondria are shown in green and fragments of damaged mitochondria in red. Some of these fragments

Updated on: March 28,2024

Mitochondrial DNA fragment losses predict Parkinson's disease before symptoms appear

byUniversity of BarcelonaImage of a fibroblast from a patient with Parkinson's disease. Mitochondria are shown in green and fragments of damaged mitochondria in red. Some of these fragments

Updated on:March 28,2024

Study hints at ways to generate new neurons in old brains

byStanford University Medical CenterCredit: CC0 Public DomainMost neurons in the human brain last a lifetime, and for good reason. Intricate, long-term information is preserved in the complex st

Updated on: October 18,2024

Study hints at ways to generate new neurons in old brains

byStanford University Medical CenterCredit: CC0 Public DomainMost neurons in the human brain last a lifetime, and for good reason. Intricate, long-term information is preserved in the complex st

Updated on:October 18,2024

Possible pathway to new therapy for Alzheimer's disease

by Boston University School of MedicineResearchers have uncovered an enzyme and a biochemical pathway they believe may lead to the identification of drugs that could inhibit the production of bet

Updated on: March 07,2024

Possible pathway to new therapy for Alzheimer's disease

by Boston University School of MedicineResearchers have uncovered an enzyme and a biochemical pathway they believe may lead to the identification of drugs that could inhibit the production of bet

Updated on:March 07,2024

Llama nanobodies: New therapy can neutralize a wide variety of HIV-1 strains

by Noelle Toumey Reetz,Georgia State UniversityCryo-EM structures of nanobodies R27 and G36 in complex with HIV-1 Env trimer reveal modes of recognition similar to J3. Credit:Advanced Scie

Updated on: August 01,2024

Llama nanobodies: New therapy can neutralize a wide variety of HIV-1 strains

by Noelle Toumey Reetz,Georgia State UniversityCryo-EM structures of nanobodies R27 and G36 in complex with HIV-1 Env trimer reveal modes of recognition similar to J3. Credit:Advanced Scie

Updated on:August 01,2024

How zebrafish map their environment: Spatial orientation mechanisms surprisingly similar to our own

by Sophia Jahns, Max Planck Institute for Biological CyberneticsIdentification of PCs in the larval zebrafish brain. Credit:Nature(2024). DOI: 10.1038/s41586-024-07867-2Researchers are tur

Updated on: September 06,2024

How zebrafish map their environment: Spatial orientation mechanisms surprisingly similar to our own

by Sophia Jahns, Max Planck Institute for Biological CyberneticsIdentification of PCs in the larval zebrafish brain. Credit:Nature(2024). DOI: 10.1038/s41586-024-07867-2Researchers are tur

Updated on:September 06,2024

Potential new biomarker for Alzheimer's discovered

by Max Delbrück Center for Molecular MedicineThe Arl8b protein (turquoise) shows an accumulation around the amyloid-b aggregates (red). Cell nuclei are stained blue. The section was analyzed with

Updated on: April 20,2024

Potential new biomarker for Alzheimer's discovered

by Max Delbrück Center for Molecular MedicineThe Arl8b protein (turquoise) shows an accumulation around the amyloid-b aggregates (red). Cell nuclei are stained blue. The section was analyzed with

Updated on:April 20,2024

Withdrawing dementia drug doubles risk of nursing home placement

by University College LondonWithdrawing a commonly-prescribed Alzheimer's disease drug from people in the advanced stages of the disease doubles their risk of being placed in a nursing home w

Updated on: February 26,2024

Withdrawing dementia drug doubles risk of nursing home placement

by University College LondonWithdrawing a commonly-prescribed Alzheimer's disease drug from people in the advanced stages of the disease doubles their risk of being placed in a nursing home w

Updated on:February 26,2024