Simple molecular reagents to treat Alzheimer's disease

by The Korea Advanced Institute of Science and Technology (KAIST)Overview of a rational strategy for designing compact aromatic molecules with multiple reactivities against pathological factors f

Updated on: June 20,2024

Simple molecular reagents to treat Alzheimer's disease

by The Korea Advanced Institute of Science and Technology (KAIST)Overview of a rational strategy for designing compact aromatic molecules with multiple reactivities against pathological factors f

Updated on:June 20,2024

Reimagining preclinical trials: Marmosets as model systems for the study of Alzheimer's disease

by University of PittsburghMarmoset models bridge the current translation gap between human studies and cell and rodent models of AD. Establishment of marmoset models of aging and genetic risk lo

Updated on: March 02,2024

Reimagining preclinical trials: Marmosets as model systems for the study of Alzheimer's disease

by University of PittsburghMarmoset models bridge the current translation gap between human studies and cell and rodent models of AD. Establishment of marmoset models of aging and genetic risk lo

Updated on:March 02,2024

Alzheimer's patients are more often hospitalized after initiating antibiotic use

by University of Eastern FinlandCredit: CC0 Public DomainPeople with Alzheimer's disease (AD) are more often hospitalized after antibiotic initiation than people without AD, a new study from

Updated on: March 09,2024

Alzheimer's patients are more often hospitalized after initiating antibiotic use

by University of Eastern FinlandCredit: CC0 Public DomainPeople with Alzheimer's disease (AD) are more often hospitalized after antibiotic initiation than people without AD, a new study from

Updated on:March 09,2024

Turning brain cells on using the power of light: Researchers refine noninvasive method of bioluminescent optogenetics

by Kelsie Smith Hayduk,University of Rochester(A) Schematic illustration of the LMO7 molecule. (B) Representative histological images showing fluorescence expression in the left SI of a mouse. (

Updated on: October 16,2024

Turning brain cells on using the power of light: Researchers refine noninvasive method of bioluminescent optogenetics

by Kelsie Smith Hayduk,University of Rochester(A) Schematic illustration of the LMO7 molecule. (B) Representative histological images showing fluorescence expression in the left SI of a mouse. (

Updated on:October 16,2024

Creating the largest, most comprehensive picture of neural connections to date

byNational Science FoundationThe 50 largest neurons of the adult fruit fly brain connectome. Credit: Tyler Sloan and Amy Sterling for FlyWire, Princeton University, (Dorkenwald et al., 2024)Flip

Updated on: October 16,2024

Creating the largest, most comprehensive picture of neural connections to date

byNational Science FoundationThe 50 largest neurons of the adult fruit fly brain connectome. Credit: Tyler Sloan and Amy Sterling for FlyWire, Princeton University, (Dorkenwald et al., 2024)Flip

Updated on:October 16,2024

Neuronal heparan sulfates play role in amyloid pathology

(HealthDay)—Neuronal heparan sulfates (HSs) modulate brain amyloid-β (Aβ) clearance and aggregation in a mouse model of Alzheimer's disease (AD), according to an experimental study published in th

Updated on: February 28,2024

Neuronal heparan sulfates play role in amyloid pathology

(HealthDay)—Neuronal heparan sulfates (HSs) modulate brain amyloid-β (Aβ) clearance and aggregation in a mouse model of Alzheimer's disease (AD), according to an experimental study published in th

Updated on:February 28,2024

People with dementia fail to get specialist care despite great need

by University College LondonCredit: University College LondonPeople suffering in the late stages of dementia receive most of their healthcare from GPs or emergency services rather than from speci

Updated on: May 08,2024

People with dementia fail to get specialist care despite great need

by University College LondonCredit: University College LondonPeople suffering in the late stages of dementia receive most of their healthcare from GPs or emergency services rather than from speci

Updated on:May 08,2024

Investigational Alzheimer's drug improves biomarkers of the disease

by Washington University School of MedicineRandall Bateman, MD, director of the Dominantly Inherited Alzheimer Network-Trials Unit (DIAN-TU), an ongoing international clinical trial to evaluate e

Updated on: April 16,2024

Investigational Alzheimer's drug improves biomarkers of the disease

by Washington University School of MedicineRandall Bateman, MD, director of the Dominantly Inherited Alzheimer Network-Trials Unit (DIAN-TU), an ongoing international clinical trial to evaluate e

Updated on:April 16,2024

Early accumulation of tau in the brain predicts memory decline in Alzheimer's disease

by Karolinska InstitutetHigh accumulation of tau in the brain measured by a PET scanner was the only biomarker that could predict cognitive decline in healthy individuals, people with mild cognit

Updated on: May 18,2024

Early accumulation of tau in the brain predicts memory decline in Alzheimer's disease

by Karolinska InstitutetHigh accumulation of tau in the brain measured by a PET scanner was the only biomarker that could predict cognitive decline in healthy individuals, people with mild cognit

Updated on:May 18,2024

Research reveals link between spinal muscular atrophy and liver damage

byAgency for Science, Technology and Research (A*STAR), SingaporeGraphical abstract. Credit:Journal of Clinical Investigation(2024). DOI: 10.1172/JCI173702An international study has

Updated on: July 31,2024

Research reveals link between spinal muscular atrophy and liver damage

byAgency for Science, Technology and Research (A*STAR), SingaporeGraphical abstract. Credit:Journal of Clinical Investigation(2024). DOI: 10.1172/JCI173702An international study has

Updated on:July 31,2024

An anti-apoE4 specific monoclonal antibody counteracts the pathological effects of apoE4 in vivo

by Bentham Science PublishersThe pathological hallmarks of Alzheimer's disease (AD), viz defective Aβ and tau proteins, have been the center of AD-directed therapeutic studies. Although this appro

Updated on: March 07,2024

An anti-apoE4 specific monoclonal antibody counteracts the pathological effects of apoE4 in vivo

by Bentham Science PublishersThe pathological hallmarks of Alzheimer's disease (AD), viz defective Aβ and tau proteins, have been the center of AD-directed therapeutic studies. Although this appro

Updated on:March 07,2024

Innovative AI solution to classify epileptic seizures

by Carnegie Mellon Portugal ProgramExamples of detection and crop, when the bed and the patient were properly detected, surrounding scenery removed, with enough space left to capture the full scale of

Updated on: February 05,2024

Innovative AI solution to classify epileptic seizures

by Carnegie Mellon Portugal ProgramExamples of detection and crop, when the bed and the patient were properly detected, surrounding scenery removed, with enough space left to capture the full scale of

Updated on:February 05,2024