Vitamin C deficiency and mitochondrial dysfunction in Alzheimer's disease

by Gabrielle Rushing,Vanderbilt UniversityEarly clinical features of sporadic Alzheimer's disease include alterations in mitochondrial functionthat appearprior to classical featu

Updated on: March 07,2024

Vitamin C deficiency and mitochondrial dysfunction in Alzheimer's disease

by Gabrielle Rushing,Vanderbilt UniversityEarly clinical features of sporadic Alzheimer's disease include alterations in mitochondrial functionthat appearprior to classical featu

Updated on:March 07,2024

Big data initiative discovers new causal pathways in Alzheimer's

by King's College LondonFlowchart of study design. CTL, cognitively normal controls; MCI, mild cognitive impairment; AD, Alzheimer's disease; Aβ, β-amyloid; CSF, cerebrospinal fluid; A, a

Updated on: May 20,2024

Big data initiative discovers new causal pathways in Alzheimer's

by King's College LondonFlowchart of study design. CTL, cognitively normal controls; MCI, mild cognitive impairment; AD, Alzheimer's disease; Aβ, β-amyloid; CSF, cerebrospinal fluid; A, a

Updated on:May 20,2024

Peptide complex in the brain is responsible for Alzheimer's disease

by Lomonosov Moscow State UniversityThe structure of the complex of β-amyloid fragment -- the product of Taiwanese mutation, with zinc ions. Credit: Vladimir Polshakov.Members of the Faculty of F

Updated on: March 09,2024

Peptide complex in the brain is responsible for Alzheimer's disease

by Lomonosov Moscow State UniversityThe structure of the complex of β-amyloid fragment -- the product of Taiwanese mutation, with zinc ions. Credit: Vladimir Polshakov.Members of the Faculty of F

Updated on:March 09,2024

Dysfunctional endosomes are early sign of neurodegeneration

by University of California - San DiegoFalse-colored scanning electron micrograph of a human neuron. Credit: Image courtesy of Thomas Deerinck, NCMIR, UC San Diego.Writing in the April 11 issue o

Updated on: February 28,2024

Dysfunctional endosomes are early sign of neurodegeneration

by University of California - San DiegoFalse-colored scanning electron micrograph of a human neuron. Credit: Image courtesy of Thomas Deerinck, NCMIR, UC San Diego.Writing in the April 11 issue o

Updated on:February 28,2024

Fructose made in the brain could be a mechanism driving Alzheimer's disease

by CU Anschutz Medical CampusCredit: Pixabay/CC0 Public DomainNew research released from the University of Colorado Anschutz Medical Campus proposes that Alzheimer's disease may be driven by

Updated on: May 18,2024

Fructose made in the brain could be a mechanism driving Alzheimer's disease

by CU Anschutz Medical CampusCredit: Pixabay/CC0 Public DomainNew research released from the University of Colorado Anschutz Medical Campus proposes that Alzheimer's disease may be driven by

Updated on:May 18,2024

Researchers determine how the hippocampus generates and sustains oscillations

byRIKENA fluorescence micrograph of a CA1 in a mouse’s hippocampus. RIKEN researchers silenced the pyramidal cells in this region. Credit: Adapted fromNature Communications(2024). DO

Updated on: August 08,2024

Researchers determine how the hippocampus generates and sustains oscillations

byRIKENA fluorescence micrograph of a CA1 in a mouse’s hippocampus. RIKEN researchers silenced the pyramidal cells in this region. Credit: Adapted fromNature Communications(2024). DO

Updated on:August 08,2024

DNA vaccine reduces both toxic proteins linked to Alzheimer's

by UT Southwestern Medical CenterToxic amyloid plaques (red) and tau tangles (brown) form on the brain of a mouse modeled to have Alzheimer's disease. A study shows a DNA vaccine reduces both

Updated on: March 30,2024

DNA vaccine reduces both toxic proteins linked to Alzheimer's

by UT Southwestern Medical CenterToxic amyloid plaques (red) and tau tangles (brown) form on the brain of a mouse modeled to have Alzheimer's disease. A study shows a DNA vaccine reduces both

Updated on:March 30,2024

Potential new biomarker for Alzheimer's discovered

by Max Delbrück Center for Molecular MedicineThe Arl8b protein (turquoise) shows an accumulation around the amyloid-b aggregates (red). Cell nuclei are stained blue. The section was analyzed with

Updated on: April 20,2024

Potential new biomarker for Alzheimer's discovered

by Max Delbrück Center for Molecular MedicineThe Arl8b protein (turquoise) shows an accumulation around the amyloid-b aggregates (red). Cell nuclei are stained blue. The section was analyzed with

Updated on:April 20,2024

Cracking the code for cerebellar movement disorders

byTexas Children's HospitalSupervised classifier model predicts mouse phenotype based on spike signatures. Credit:eLife(2024). DOI: 10.7554/eLife.91483.2The cerebellum is a regio

Updated on: July 05,2024

Cracking the code for cerebellar movement disorders

byTexas Children's HospitalSupervised classifier model predicts mouse phenotype based on spike signatures. Credit:eLife(2024). DOI: 10.7554/eLife.91483.2The cerebellum is a regio

Updated on:July 05,2024

Large amounts of sedentary time linked with higher risk of dementia in older adults, study shows

by University of Southern CaliforniaCredit: CC0 Public DomainAdults aged 60 and older who spend more time engaging in sedentary behaviors like sitting while watching TV or driving may be at incre

Updated on: March 02,2024

Large amounts of sedentary time linked with higher risk of dementia in older adults, study shows

by University of Southern CaliforniaCredit: CC0 Public DomainAdults aged 60 and older who spend more time engaging in sedentary behaviors like sitting while watching TV or driving may be at incre

Updated on:March 02,2024

Study finds tumor growth fueled by nucleotide salvage

byUTSouthwestern Medical CenterGraphical abstract. Credit:Cell(2024). DOI: 10.1016/j.cell.2024.05.011Cancer cells salvage purine nucleotides to fuel tumor growth, including pur

Updated on: August 01,2024

Study finds tumor growth fueled by nucleotide salvage

byUTSouthwestern Medical CenterGraphical abstract. Credit:Cell(2024). DOI: 10.1016/j.cell.2024.05.011Cancer cells salvage purine nucleotides to fuel tumor growth, including pur

Updated on:August 01,2024

Alzheimer's disease diagnostics could become more accessible

by National University of Science and Technology MISISNational University of Science and Technology MISISA team of researchers from the Laboratory of Biophysics at NUST MISIS, Lomonosov Moscow State U

Updated on: April 08,2024

Alzheimer's disease diagnostics could become more accessible

by National University of Science and Technology MISISNational University of Science and Technology MISISA team of researchers from the Laboratory of Biophysics at NUST MISIS, Lomonosov Moscow State U

Updated on:April 08,2024