Precision medicine data dive shows water pill may be viable to test as Alzheimer's treatment

by National Institutes of HealthPET scan of a human brain with Alzheimer's disease. Credit: public domainA commonly available oral diuretic pill approved by the U.S. Food and Drug Administrat

Updated on: July 04,2024

Precision medicine data dive shows water pill may be viable to test as Alzheimer's treatment

by National Institutes of HealthPET scan of a human brain with Alzheimer's disease. Credit: public domainA commonly available oral diuretic pill approved by the U.S. Food and Drug Administrat

Updated on:July 04,2024

Artificial intelligence predicts dementia before onset of symptoms

by McGill UniversityCredit: McGill UniversityImagine if doctors could determine, many years in advance, who is likely to develop dementia. Such prognostic capabilities would give patients and the

Updated on: March 09,2024

Artificial intelligence predicts dementia before onset of symptoms

by McGill UniversityCredit: McGill UniversityImagine if doctors could determine, many years in advance, who is likely to develop dementia. Such prognostic capabilities would give patients and the

Updated on:March 09,2024

Long-term use of opioid patches common among persons with Alzheimer's disease

by University of Eastern FinlandApproximately seven per cent of persons with Alzheimer's disease use strong pain medicines, opioids, for non-cancer pain for a period longer than six months, a

Updated on: March 07,2024

Long-term use of opioid patches common among persons with Alzheimer's disease

by University of Eastern FinlandApproximately seven per cent of persons with Alzheimer's disease use strong pain medicines, opioids, for non-cancer pain for a period longer than six months, a

Updated on:March 07,2024

Accurate and continuous remote monitoring of step length can be sensitive marker for neurological diseases and aging

byTel-Aviv UniversityA person walking in a state-of-the-art gait lab, with a wearable sensor positioned on his lower back. He is walking over a gait mat embedded with force-sensitive sensors. Th

Updated on: July 17,2024

Accurate and continuous remote monitoring of step length can be sensitive marker for neurological diseases and aging

byTel-Aviv UniversityA person walking in a state-of-the-art gait lab, with a wearable sensor positioned on his lower back. He is walking over a gait mat embedded with force-sensitive sensors. Th

Updated on:July 17,2024

'Lesser of two evils' argument used to defend antipsychotic overuse for dementia

by University of ReadingCredit: University of ReadingThe increasing use of antipsychotic drugs to manage dementia in care homes has been explained by some practitioners as "the lesser of two

Updated on: March 09,2024

'Lesser of two evils' argument used to defend antipsychotic overuse for dementia

by University of ReadingCredit: University of ReadingThe increasing use of antipsychotic drugs to manage dementia in care homes has been explained by some practitioners as "the lesser of two

Updated on:March 09,2024

Neuronal heparan sulfates play role in amyloid pathology

(HealthDay)—Neuronal heparan sulfates (HSs) modulate brain amyloid-β (Aβ) clearance and aggregation in a mouse model of Alzheimer's disease (AD), according to an experimental study published in th

Updated on: February 28,2024

Neuronal heparan sulfates play role in amyloid pathology

(HealthDay)—Neuronal heparan sulfates (HSs) modulate brain amyloid-β (Aβ) clearance and aggregation in a mouse model of Alzheimer's disease (AD), according to an experimental study published in th

Updated on:February 28,2024

Early accumulation of tau in the brain predicts memory decline in Alzheimer's disease

by Karolinska InstitutetHigh accumulation of tau in the brain measured by a PET scanner was the only biomarker that could predict cognitive decline in healthy individuals, people with mild cognit

Updated on: May 18,2024

Early accumulation of tau in the brain predicts memory decline in Alzheimer's disease

by Karolinska InstitutetHigh accumulation of tau in the brain measured by a PET scanner was the only biomarker that could predict cognitive decline in healthy individuals, people with mild cognit

Updated on:May 18,2024

Detecting dementia in the blood

by Swiss Federal Laboratories for Materials Science and TechnologyEmpa researcher Peter Nirmalraj analyzes blood samples using atomic force microscopy (AFM). Credit: EmpaIf the suspicion of Alzhe

Updated on: March 30,2024

Detecting dementia in the blood

by Swiss Federal Laboratories for Materials Science and TechnologyEmpa researcher Peter Nirmalraj analyzes blood samples using atomic force microscopy (AFM). Credit: EmpaIf the suspicion of Alzhe

Updated on:March 30,2024

Reimagining preclinical trials: Marmosets as model systems for the study of Alzheimer's disease

by University of PittsburghMarmoset models bridge the current translation gap between human studies and cell and rodent models of AD. Establishment of marmoset models of aging and genetic risk lo

Updated on: March 02,2024

Reimagining preclinical trials: Marmosets as model systems for the study of Alzheimer's disease

by University of PittsburghMarmoset models bridge the current translation gap between human studies and cell and rodent models of AD. Establishment of marmoset models of aging and genetic risk lo

Updated on:March 02,2024

Neuroscientists find that animals replay incidentally encoded episodic memories

byIndiana UniversityGraphical abstract. Credit:Current Biology(2024). DOI: 10.1016/j.cub.2023.12.043Indiana University neuroscientists have found the first evidence that rodents can

Updated on: March 13,2024

Neuroscientists find that animals replay incidentally encoded episodic memories

byIndiana UniversityGraphical abstract. Credit:Current Biology(2024). DOI: 10.1016/j.cub.2023.12.043Indiana University neuroscientists have found the first evidence that rodents can

Updated on:March 13,2024

Optogenetics approach reveals how alcohol use disorder impairs cognitive flexibility

by Danielle Michaud,Texas A&M UniversityExcessive alcohol intake reduces thalamically evoked burst-pause response in DMS CINs and impairs reversal of operant conditioning. Credit:Scien

Updated on: January 15,2025

Optogenetics approach reveals how alcohol use disorder impairs cognitive flexibility

by Danielle Michaud,Texas A&M UniversityExcessive alcohol intake reduces thalamically evoked burst-pause response in DMS CINs and impairs reversal of operant conditioning. Credit:Scien

Updated on:January 15,2025

Comparing the polarimetric properties of fresh and preserved brain tissue

by SPIEWhile preserving brain tissue samples in formalin slightly alters their polarimetric properties, they are still similar to those of fresh samples, making them suitable for training machine

Updated on: February 05,2024

Comparing the polarimetric properties of fresh and preserved brain tissue

by SPIEWhile preserving brain tissue samples in formalin slightly alters their polarimetric properties, they are still similar to those of fresh samples, making them suitable for training machine

Updated on:February 05,2024