Unlocking Alzheimer's mysteries: A comprehensive brain connectome-based survey

by TranSpreadStructural connectivity (SC) refers to anatomical links and is usually estimated using fiber bundles derived from diffusion MRI; Functional connectivity (FC) and effective connectivity (E

Updated on: March 28,2024

Unlocking Alzheimer's mysteries: A comprehensive brain connectome-based survey

by TranSpreadStructural connectivity (SC) refers to anatomical links and is usually estimated using fiber bundles derived from diffusion MRI; Functional connectivity (FC) and effective connectivity (E

Updated on:March 28,2024

More than half of persons with Alzheimer's disease aged 90 years or more use psychotropic drugs

by University of Eastern FinlandPsychotropic drug use is rather common among persons aged 90 years or more diagnosed with Alzheimer's disease, compared with those who were diagnosed at younge

Updated on: March 07,2024

More than half of persons with Alzheimer's disease aged 90 years or more use psychotropic drugs

by University of Eastern FinlandPsychotropic drug use is rather common among persons aged 90 years or more diagnosed with Alzheimer's disease, compared with those who were diagnosed at younge

Updated on:March 07,2024

Untangling tau—researchers find a 'druggable target' for treating Alzheimer's disease

by University of California - San DiegoA micrograph by Thomas Deerinck of the National Center for Microscopy and Imaging Research at UC San Diego School of Medicine depicts tangles of tau protein

Updated on: July 01,2024

Untangling tau—researchers find a 'druggable target' for treating Alzheimer's disease

by University of California - San DiegoA micrograph by Thomas Deerinck of the National Center for Microscopy and Imaging Research at UC San Diego School of Medicine depicts tangles of tau protein

Updated on:July 01,2024

AI decodes whole-cortex functional images to predict behavioral states

byKobe UniversityA new "end-to-end" deep learning method for the prediction of behavioral states uses whole-cortex functional imaging that do not require preprocessing or pre-specified

Updated on: March 28,2024

AI decodes whole-cortex functional images to predict behavioral states

byKobe UniversityA new "end-to-end" deep learning method for the prediction of behavioral states uses whole-cortex functional imaging that do not require preprocessing or pre-specified

Updated on:March 28,2024

Detecting dementia in the blood

by Swiss Federal Laboratories for Materials Science and TechnologyEmpa researcher Peter Nirmalraj analyzes blood samples using atomic force microscopy (AFM). Credit: EmpaIf the suspicion of Alzhe

Updated on: March 30,2024

Detecting dementia in the blood

by Swiss Federal Laboratories for Materials Science and TechnologyEmpa researcher Peter Nirmalraj analyzes blood samples using atomic force microscopy (AFM). Credit: EmpaIf the suspicion of Alzhe

Updated on:March 30,2024

Research reveals environmental and disease factors can speed up the brain's biological age

byTrinity College DublinDataset characterization and analysis pipeline. Credit:Nature Medicine(2024). DOI: 10.1038/s41591-024-03209-xThe pace at which the brain ages can vary signifi

Updated on: September 06,2024

Research reveals environmental and disease factors can speed up the brain's biological age

byTrinity College DublinDataset characterization and analysis pipeline. Credit:Nature Medicine(2024). DOI: 10.1038/s41591-024-03209-xThe pace at which the brain ages can vary signifi

Updated on:September 06,2024

Modulation of brain cholesterol: A new line of research in Alzheimer's disease treatment?

by Institut National de la Sante et de la Recherche MedicaleFluorescent labelling of the Tau protein in a hNT human cell. Credit: ©Inserm/U837We have known for some years that Alzheimer&#39

Updated on: February 26,2024

Modulation of brain cholesterol: A new line of research in Alzheimer's disease treatment?

by Institut National de la Sante et de la Recherche MedicaleFluorescent labelling of the Tau protein in a hNT human cell. Credit: ©Inserm/U837We have known for some years that Alzheimer&#39

Updated on:February 26,2024

Study finds no uniform brain shrinkage pattern in Alzheimer's

byUniversity College LondonMapped is the proportion of participants with a high rate of atrophy in cortical (left) and subcortical (right) areas. AD, Alzheimer's disease; MCI, mild cognitive

Updated on: October 16,2024

Study finds no uniform brain shrinkage pattern in Alzheimer's

byUniversity College LondonMapped is the proportion of participants with a high rate of atrophy in cortical (left) and subcortical (right) areas. AD, Alzheimer's disease; MCI, mild cognitive

Updated on:October 16,2024

Cracking the code for cerebellar movement disorders

byTexas Children's HospitalSupervised classifier model predicts mouse phenotype based on spike signatures. Credit:eLife(2024). DOI: 10.7554/eLife.91483.2The cerebellum is a regio

Updated on: July 05,2024

Cracking the code for cerebellar movement disorders

byTexas Children's HospitalSupervised classifier model predicts mouse phenotype based on spike signatures. Credit:eLife(2024). DOI: 10.7554/eLife.91483.2The cerebellum is a regio

Updated on:July 05,2024

How an Alzheimer's-related protein forms plaques

by Leiden UniversityCredit: Leiden UniversityNeurological diseases such as Alzheimer's disease are characterised by aggregates of protein in the brain. The connection of these aggregates to t

Updated on: March 09,2024

How an Alzheimer's-related protein forms plaques

by Leiden UniversityCredit: Leiden UniversityNeurological diseases such as Alzheimer's disease are characterised by aggregates of protein in the brain. The connection of these aggregates to t

Updated on:March 09,2024

Alzheimer's-disease-related proteases control axonal guidance by regulating growth cone dynamics

by VIB (the Flanders Institute for Biotechnology)Diagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.BACE1 is the major drug target for Alzheimer's

Updated on: February 26,2024

Alzheimer's-disease-related proteases control axonal guidance by regulating growth cone dynamics

by VIB (the Flanders Institute for Biotechnology)Diagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.BACE1 is the major drug target for Alzheimer's

Updated on:February 26,2024

Stimulating brain circuits promotes neuron growth in adulthood, improving cognition and mood

by University of North Carolina Health CareNew adult-born neurons that contribute to memory and emotion regulation. Credit: Song Lab, UNC-CHWe humans lose mental acuity as an unfortunate side eff

Updated on: February 18,2024

Stimulating brain circuits promotes neuron growth in adulthood, improving cognition and mood

by University of North Carolina Health CareNew adult-born neurons that contribute to memory and emotion regulation. Credit: Song Lab, UNC-CHWe humans lose mental acuity as an unfortunate side eff

Updated on:February 18,2024