Neuronal heparan sulfates play role in amyloid pathology

(HealthDay)—Neuronal heparan sulfates (HSs) modulate brain amyloid-β (Aβ) clearance and aggregation in a mouse model of Alzheimer's disease (AD), according to an experimental study published in th

Updated on: February 28,2024

Neuronal heparan sulfates play role in amyloid pathology

(HealthDay)—Neuronal heparan sulfates (HSs) modulate brain amyloid-β (Aβ) clearance and aggregation in a mouse model of Alzheimer's disease (AD), according to an experimental study published in th

Updated on:February 28,2024

Long-term use of opioid patches common among persons with Alzheimer's disease

by University of Eastern FinlandApproximately seven per cent of persons with Alzheimer's disease use strong pain medicines, opioids, for non-cancer pain for a period longer than six months, a

Updated on: March 07,2024

Long-term use of opioid patches common among persons with Alzheimer's disease

by University of Eastern FinlandApproximately seven per cent of persons with Alzheimer's disease use strong pain medicines, opioids, for non-cancer pain for a period longer than six months, a

Updated on:March 07,2024

Brain takes a beating as arteries age

by Umea UniversityCredit: CC0 Public DomainResearchers in Umeå, Sweden, have presented a model that explains why memory deteriorates as the body ages. With age, the brain receives an increased lo

Updated on: May 20,2024

Brain takes a beating as arteries age

by Umea UniversityCredit: CC0 Public DomainResearchers in Umeå, Sweden, have presented a model that explains why memory deteriorates as the body ages. With age, the brain receives an increased lo

Updated on:May 20,2024

Reimagining preclinical trials: Marmosets as model systems for the study of Alzheimer's disease

by University of PittsburghMarmoset models bridge the current translation gap between human studies and cell and rodent models of AD. Establishment of marmoset models of aging and genetic risk lo

Updated on: March 02,2024

Reimagining preclinical trials: Marmosets as model systems for the study of Alzheimer's disease

by University of PittsburghMarmoset models bridge the current translation gap between human studies and cell and rodent models of AD. Establishment of marmoset models of aging and genetic risk lo

Updated on:March 02,2024

Optogenetics approach reveals how alcohol use disorder impairs cognitive flexibility

by Danielle Michaud,Texas A&M UniversityExcessive alcohol intake reduces thalamically evoked burst-pause response in DMS CINs and impairs reversal of operant conditioning. Credit:Scien

Updated on: January 15,2025

Optogenetics approach reveals how alcohol use disorder impairs cognitive flexibility

by Danielle Michaud,Texas A&M UniversityExcessive alcohol intake reduces thalamically evoked burst-pause response in DMS CINs and impairs reversal of operant conditioning. Credit:Scien

Updated on:January 15,2025

Comparing the polarimetric properties of fresh and preserved brain tissue

by SPIEWhile preserving brain tissue samples in formalin slightly alters their polarimetric properties, they are still similar to those of fresh samples, making them suitable for training machine

Updated on: February 05,2024

Comparing the polarimetric properties of fresh and preserved brain tissue

by SPIEWhile preserving brain tissue samples in formalin slightly alters their polarimetric properties, they are still similar to those of fresh samples, making them suitable for training machine

Updated on:February 05,2024

Alzheimer's patients are more often hospitalized after initiating antibiotic use

by University of Eastern FinlandCredit: CC0 Public DomainPeople with Alzheimer's disease (AD) are more often hospitalized after antibiotic initiation than people without AD, a new study from

Updated on: March 09,2024

Alzheimer's patients are more often hospitalized after initiating antibiotic use

by University of Eastern FinlandCredit: CC0 Public DomainPeople with Alzheimer's disease (AD) are more often hospitalized after antibiotic initiation than people without AD, a new study from

Updated on:March 09,2024

Investigational Alzheimer's drug improves biomarkers of the disease

by Washington University School of MedicineRandall Bateman, MD, director of the Dominantly Inherited Alzheimer Network-Trials Unit (DIAN-TU), an ongoing international clinical trial to evaluate e

Updated on: April 16,2024

Investigational Alzheimer's drug improves biomarkers of the disease

by Washington University School of MedicineRandall Bateman, MD, director of the Dominantly Inherited Alzheimer Network-Trials Unit (DIAN-TU), an ongoing international clinical trial to evaluate e

Updated on:April 16,2024

Detecting dementia in the blood

by Swiss Federal Laboratories for Materials Science and TechnologyEmpa researcher Peter Nirmalraj analyzes blood samples using atomic force microscopy (AFM). Credit: EmpaIf the suspicion of Alzhe

Updated on: March 30,2024

Detecting dementia in the blood

by Swiss Federal Laboratories for Materials Science and TechnologyEmpa researcher Peter Nirmalraj analyzes blood samples using atomic force microscopy (AFM). Credit: EmpaIf the suspicion of Alzhe

Updated on:March 30,2024

Neuroscientists find that animals replay incidentally encoded episodic memories

byIndiana UniversityGraphical abstract. Credit:Current Biology(2024). DOI: 10.1016/j.cub.2023.12.043Indiana University neuroscientists have found the first evidence that rodents can

Updated on: March 13,2024

Neuroscientists find that animals replay incidentally encoded episodic memories

byIndiana UniversityGraphical abstract. Credit:Current Biology(2024). DOI: 10.1016/j.cub.2023.12.043Indiana University neuroscientists have found the first evidence that rodents can

Updated on:March 13,2024

Accurate and continuous remote monitoring of step length can be sensitive marker for neurological diseases and aging

byTel-Aviv UniversityA person walking in a state-of-the-art gait lab, with a wearable sensor positioned on his lower back. He is walking over a gait mat embedded with force-sensitive sensors. Th

Updated on: July 17,2024

Accurate and continuous remote monitoring of step length can be sensitive marker for neurological diseases and aging

byTel-Aviv UniversityA person walking in a state-of-the-art gait lab, with a wearable sensor positioned on his lower back. He is walking over a gait mat embedded with force-sensitive sensors. Th

Updated on:July 17,2024

When memory loss should concern you

by Lauren Woods,University of ConnecticutCredit: AI-generated imageAlthough there is currently no cure for Alzheimer's Disease, Dr. Patrick Coll of UConn's Center on Aging recommends ear

Updated on: February 27,2024

When memory loss should concern you

by Lauren Woods,University of ConnecticutCredit: AI-generated imageAlthough there is currently no cure for Alzheimer's Disease, Dr. Patrick Coll of UConn's Center on Aging recommends ear

Updated on:February 27,2024