Study finds tumor growth fueled by nucleotide salvage

byUTSouthwestern Medical CenterGraphical abstract. Credit:Cell(2024). DOI: 10.1016/j.cell.2024.05.011Cancer cells salvage purine nucleotides to fuel tumor growth, including pur

Updated on: August 01,2024

Study finds tumor growth fueled by nucleotide salvage

byUTSouthwestern Medical CenterGraphical abstract. Credit:Cell(2024). DOI: 10.1016/j.cell.2024.05.011Cancer cells salvage purine nucleotides to fuel tumor growth, including pur

Updated on:August 01,2024

Dysfunctional endosomes are early sign of neurodegeneration

by University of California - San DiegoFalse-colored scanning electron micrograph of a human neuron. Credit: Image courtesy of Thomas Deerinck, NCMIR, UC San Diego.Writing in the April 11 issue o

Updated on: February 28,2024

Dysfunctional endosomes are early sign of neurodegeneration

by University of California - San DiegoFalse-colored scanning electron micrograph of a human neuron. Credit: Image courtesy of Thomas Deerinck, NCMIR, UC San Diego.Writing in the April 11 issue o

Updated on:February 28,2024

Dementia prevention study signs up first recruit

by University of EdinburghJulie Duffus from near Edinburgh, Scotland, is the first participant to enrol in a major dementia prevention study led by the University of Edinburgh. Credit: Maverick P

Updated on: May 11,2024

Dementia prevention study signs up first recruit

by University of EdinburghJulie Duffus from near Edinburgh, Scotland, is the first participant to enrol in a major dementia prevention study led by the University of Edinburgh. Credit: Maverick P

Updated on:May 11,2024

An implant to prevent Alzheimer's

by Ecole Polytechnique Federale de LausanneAn infographic of how the implanted capsule releases antibodies to the brain. Credit: Patrick Aebischer (EPFL)In a cutting-edge treatment for Alzheimer&

Updated on: February 28,2024

An implant to prevent Alzheimer's

by Ecole Polytechnique Federale de LausanneAn infographic of how the implanted capsule releases antibodies to the brain. Credit: Patrick Aebischer (EPFL)In a cutting-edge treatment for Alzheimer&

Updated on:February 28,2024

Homocysteine tied to Alzheimer's via A-beta-fibrinogen interaction

(HealthDay)—Plasma homocysteine (HC) and its metabolite homocysteine thiolactone (HCTL) contribute to Alzheimer's disease (AD) pathology via the amyloid-β (Aβ)-fibrinogen interaction, according to

Updated on: February 28,2024

Homocysteine tied to Alzheimer's via A-beta-fibrinogen interaction

(HealthDay)—Plasma homocysteine (HC) and its metabolite homocysteine thiolactone (HCTL) contribute to Alzheimer's disease (AD) pathology via the amyloid-β (Aβ)-fibrinogen interaction, according to

Updated on:February 28,2024

Investigational Alzheimer's drug improves biomarkers of the disease

by Washington University School of MedicineRandall Bateman, MD, director of the Dominantly Inherited Alzheimer Network-Trials Unit (DIAN-TU), an ongoing international clinical trial to evaluate e

Updated on: April 16,2024

Investigational Alzheimer's drug improves biomarkers of the disease

by Washington University School of MedicineRandall Bateman, MD, director of the Dominantly Inherited Alzheimer Network-Trials Unit (DIAN-TU), an ongoing international clinical trial to evaluate e

Updated on:April 16,2024

Benzodiazepines increase mortality in persons with Alzheimer's disease

by University of Eastern FinlandBenzodiazepine and related drug use is associated with a 40 percent increase in mortality among persons with Alzheimer's disease, according to a new study from

Updated on: March 07,2024

Benzodiazepines increase mortality in persons with Alzheimer's disease

by University of Eastern FinlandBenzodiazepine and related drug use is associated with a 40 percent increase in mortality among persons with Alzheimer's disease, according to a new study from

Updated on:March 07,2024

Diabetes drug shows promise for safely treating, detecting Alzheimer's disease

by Boston University Medical CenterAs the number of patients with Alzheimer's disease (AD) rapidly increases, new treatments as well as blood tests that are simple and can be easily performed

Updated on: March 07,2024

Diabetes drug shows promise for safely treating, detecting Alzheimer's disease

by Boston University Medical CenterAs the number of patients with Alzheimer's disease (AD) rapidly increases, new treatments as well as blood tests that are simple and can be easily performed

Updated on:March 07,2024

Modulation of brain cholesterol: A new line of research in Alzheimer's disease treatment?

by Institut National de la Sante et de la Recherche MedicaleFluorescent labelling of the Tau protein in a hNT human cell. Credit: ©Inserm/U837We have known for some years that Alzheimer&#39

Updated on: February 26,2024

Modulation of brain cholesterol: A new line of research in Alzheimer's disease treatment?

by Institut National de la Sante et de la Recherche MedicaleFluorescent labelling of the Tau protein in a hNT human cell. Credit: ©Inserm/U837We have known for some years that Alzheimer&#39

Updated on:February 26,2024

Does persistent pain impact older adults' physical function, cognition, and well-being?

by WileyCredit: Unsplash/CC0 Public DomainIn a study in theJournal of the American Geriatrics Societyof 5,589 US adults aged 65 years and older, persistent pain was common and was lin

Updated on: February 05,2024

Does persistent pain impact older adults' physical function, cognition, and well-being?

by WileyCredit: Unsplash/CC0 Public DomainIn a study in theJournal of the American Geriatrics Societyof 5,589 US adults aged 65 years and older, persistent pain was common and was lin

Updated on:February 05,2024

Neural circuits reveal new insights into how we navigate space and store memories

by Pat Harriman,University of California, IrvineDistinct RSC neuronal circuits corresponding to M2- and AD-projection neurons revealed by retrograde adeno-associated (rAAV2-retro) virus and ante

Updated on: November 28,2024

Neural circuits reveal new insights into how we navigate space and store memories

by Pat Harriman,University of California, IrvineDistinct RSC neuronal circuits corresponding to M2- and AD-projection neurons revealed by retrograde adeno-associated (rAAV2-retro) virus and ante

Updated on:November 28,2024

Extending use of existing Alzheimer's drug could delay move into nursing home

by Alzheimer's Research UKDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.Newly-released follow-up analysis from a 2012 clinical trial led by a

Updated on: February 26,2024

Extending use of existing Alzheimer's drug could delay move into nursing home

by Alzheimer's Research UKDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.Newly-released follow-up analysis from a 2012 clinical trial led by a

Updated on:February 26,2024