Genetic risk factors for Alzheimer's disease may be detectable even in young adults

by American Academy of NeurologyCredit: CC0 Public DomainNew research shows that a genetic risk score may detect those at higher risk for Alzheimer's disease long before symptoms appear—even

Updated on: April 08,2024

Genetic risk factors for Alzheimer's disease may be detectable even in young adults

by American Academy of NeurologyCredit: CC0 Public DomainNew research shows that a genetic risk score may detect those at higher risk for Alzheimer's disease long before symptoms appear—even

Updated on:April 08,2024

Dietary fat alone does not cause changes in the hypothalamus, mouse study finds

by Deutsches Zentrum fuer Diabetesforschung DZDConfocal image representing the immunolabelling of AgRP and Synaptophysin-TdTomato in the paraventricular nucleus of the hypothalamus anterior (PVH ant)

Updated on: October 18,2024

Dietary fat alone does not cause changes in the hypothalamus, mouse study finds

by Deutsches Zentrum fuer Diabetesforschung DZDConfocal image representing the immunolabelling of AgRP and Synaptophysin-TdTomato in the paraventricular nucleus of the hypothalamus anterior (PVH ant)

Updated on:October 18,2024

Sleep deprivation in mice found to reduce brain synapse diversity

by Bob Yirka , Medical XpressCredit:Current Biology(2024). DOI: 10.1016/j.cub.2024.07.032A multi-disciplinary team has found that depriving lab mice of sleep can lead to a reduction in syn

Updated on: August 08,2024

Sleep deprivation in mice found to reduce brain synapse diversity

by Bob Yirka , Medical XpressCredit:Current Biology(2024). DOI: 10.1016/j.cub.2024.07.032A multi-disciplinary team has found that depriving lab mice of sleep can lead to a reduction in syn

Updated on:August 08,2024

An anti-apoE4 specific monoclonal antibody counteracts the pathological effects of apoE4 in vivo

by Bentham Science PublishersThe pathological hallmarks of Alzheimer's disease (AD), viz defective Aβ and tau proteins, have been the center of AD-directed therapeutic studies. Although this appro

Updated on: March 07,2024

An anti-apoE4 specific monoclonal antibody counteracts the pathological effects of apoE4 in vivo

by Bentham Science PublishersThe pathological hallmarks of Alzheimer's disease (AD), viz defective Aβ and tau proteins, have been the center of AD-directed therapeutic studies. Although this appro

Updated on:March 07,2024

Alzheimer's disease: How amyloid aggregates alter neuronal function

by CNRSRat hippocampal neurons in primary culture, showing a fluorescent soluble protein (left) and trajectories corresponding to the movement of the glutamate receptors on its surface, measured

Updated on: April 08,2024

Alzheimer's disease: How amyloid aggregates alter neuronal function

by CNRSRat hippocampal neurons in primary culture, showing a fluorescent soluble protein (left) and trajectories corresponding to the movement of the glutamate receptors on its surface, measured

Updated on:April 08,2024

The search for early markers of Alzheimer's Disease

by Ríona Mc Ardle,Public Library of ScienceRegional MRI predictors of MCI-to-dementia progression. Figure courtesy Korolev et al. via PLOS One.This eloquent quote by V.S. Ramachandran expresses

Updated on: February 28,2024

The search for early markers of Alzheimer's Disease

by Ríona Mc Ardle,Public Library of ScienceRegional MRI predictors of MCI-to-dementia progression. Figure courtesy Korolev et al. via PLOS One.This eloquent quote by V.S. Ramachandran expresses

Updated on:February 28,2024

Reimagining preclinical trials: Marmosets as model systems for the study of Alzheimer's disease

by University of PittsburghMarmoset models bridge the current translation gap between human studies and cell and rodent models of AD. Establishment of marmoset models of aging and genetic risk lo

Updated on: March 02,2024

Reimagining preclinical trials: Marmosets as model systems for the study of Alzheimer's disease

by University of PittsburghMarmoset models bridge the current translation gap between human studies and cell and rodent models of AD. Establishment of marmoset models of aging and genetic risk lo

Updated on:March 02,2024

Control of the iRhom2 protein may hold the key to preventing Alzheimer's disease

by CORDISCredit: IRHOM2 in ADIt is known that the onset of Alzheimer's disease (AD) is associated with the accumulation of Amyloid beta (Aβ) peptides in small molecular clusters known as olig

Updated on: March 09,2024

Control of the iRhom2 protein may hold the key to preventing Alzheimer's disease

by CORDISCredit: IRHOM2 in ADIt is known that the onset of Alzheimer's disease (AD) is associated with the accumulation of Amyloid beta (Aβ) peptides in small molecular clusters known as olig

Updated on:March 09,2024

Rehabilitation approach combines spinal and hip stimulation to improve walking speed in patients with stroke

Updated on: September 02,2025

Rehabilitation approach combines spinal and hip stimulation to improve walking speed in patients with stroke

Updated on:September 02,2025

Research provides insight into the role of the western diet in Alzheimer's disease

by Jackson LaboratoryRecent research has established associations between certain environmental factors, including eating a western diet and being sedentary, with an increased susceptibility to A

Updated on: February 28,2024

Research provides insight into the role of the western diet in Alzheimer's disease

by Jackson LaboratoryRecent research has established associations between certain environmental factors, including eating a western diet and being sedentary, with an increased susceptibility to A

Updated on:February 28,2024

Alzheimer's researchers find clues to toxic forms of amyloid beta

by University of California - Santa CruzDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.Much of the research on Alzheimer's disease has focused

Updated on: April 16,2024

Alzheimer's researchers find clues to toxic forms of amyloid beta

by University of California - Santa CruzDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.Much of the research on Alzheimer's disease has focused

Updated on:April 16,2024

Using tau imaging as diagnostic marker for Alzheimer disease

by The JAMA Network JournalsThe accumulation of β-Amyloid (Αβ) and tau proteins in the brain is hallmark pathology for Alzheimer disease. Recently developed positron emission tomography (PET) tra

Updated on: March 07,2024

Using tau imaging as diagnostic marker for Alzheimer disease

by The JAMA Network JournalsThe accumulation of β-Amyloid (Αβ) and tau proteins in the brain is hallmark pathology for Alzheimer disease. Recently developed positron emission tomography (PET) tra

Updated on:March 07,2024