An anti-apoE4 specific monoclonal antibody counteracts the pathological effects of apoE4 in vivo

by Bentham Science PublishersThe pathological hallmarks of Alzheimer's disease (AD), viz defective Aβ and tau proteins, have been the center of AD-directed therapeutic studies. Although this appro

Updated on: March 07,2024

An anti-apoE4 specific monoclonal antibody counteracts the pathological effects of apoE4 in vivo

by Bentham Science PublishersThe pathological hallmarks of Alzheimer's disease (AD), viz defective Aβ and tau proteins, have been the center of AD-directed therapeutic studies. Although this appro

Updated on:March 07,2024

Dietary fat alone does not cause changes in the hypothalamus, mouse study finds

by Deutsches Zentrum fuer Diabetesforschung DZDConfocal image representing the immunolabelling of AgRP and Synaptophysin-TdTomato in the paraventricular nucleus of the hypothalamus anterior (PVH ant)

Updated on: October 18,2024

Dietary fat alone does not cause changes in the hypothalamus, mouse study finds

by Deutsches Zentrum fuer Diabetesforschung DZDConfocal image representing the immunolabelling of AgRP and Synaptophysin-TdTomato in the paraventricular nucleus of the hypothalamus anterior (PVH ant)

Updated on:October 18,2024

Alzheimer's researchers find clues to toxic forms of amyloid beta

by University of California - Santa CruzDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.Much of the research on Alzheimer's disease has focused

Updated on: April 16,2024

Alzheimer's researchers find clues to toxic forms of amyloid beta

by University of California - Santa CruzDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.Much of the research on Alzheimer's disease has focused

Updated on:April 16,2024

Homocysteine tied to Alzheimer's via A-beta-fibrinogen interaction

(HealthDay)—Plasma homocysteine (HC) and its metabolite homocysteine thiolactone (HCTL) contribute to Alzheimer's disease (AD) pathology via the amyloid-β (Aβ)-fibrinogen interaction, according to

Updated on: February 28,2024

Homocysteine tied to Alzheimer's via A-beta-fibrinogen interaction

(HealthDay)—Plasma homocysteine (HC) and its metabolite homocysteine thiolactone (HCTL) contribute to Alzheimer's disease (AD) pathology via the amyloid-β (Aβ)-fibrinogen interaction, according to

Updated on:February 28,2024

The search for early markers of Alzheimer's Disease

by Ríona Mc Ardle,Public Library of ScienceRegional MRI predictors of MCI-to-dementia progression. Figure courtesy Korolev et al. via PLOS One.This eloquent quote by V.S. Ramachandran expresses

Updated on: February 28,2024

The search for early markers of Alzheimer's Disease

by Ríona Mc Ardle,Public Library of ScienceRegional MRI predictors of MCI-to-dementia progression. Figure courtesy Korolev et al. via PLOS One.This eloquent quote by V.S. Ramachandran expresses

Updated on:February 28,2024

Reimagining preclinical trials: Marmosets as model systems for the study of Alzheimer's disease

by University of PittsburghMarmoset models bridge the current translation gap between human studies and cell and rodent models of AD. Establishment of marmoset models of aging and genetic risk lo

Updated on: March 02,2024

Reimagining preclinical trials: Marmosets as model systems for the study of Alzheimer's disease

by University of PittsburghMarmoset models bridge the current translation gap between human studies and cell and rodent models of AD. Establishment of marmoset models of aging and genetic risk lo

Updated on:March 02,2024

Researchers create a new window on leading genetic cause of Alzheimer's

by Pacific Northwest National LaboratoryWorkflow for molecular characterization of CSF-Lps.Lipoproteins are exchange labeled with a rhodamine-containing phospholipid and size distribution determi

Updated on: March 02,2024

Researchers create a new window on leading genetic cause of Alzheimer's

by Pacific Northwest National LaboratoryWorkflow for molecular characterization of CSF-Lps.Lipoproteins are exchange labeled with a rhodamine-containing phospholipid and size distribution determi

Updated on:March 02,2024

Research provides insight into the role of the western diet in Alzheimer's disease

by Jackson LaboratoryRecent research has established associations between certain environmental factors, including eating a western diet and being sedentary, with an increased susceptibility to A

Updated on: February 28,2024

Research provides insight into the role of the western diet in Alzheimer's disease

by Jackson LaboratoryRecent research has established associations between certain environmental factors, including eating a western diet and being sedentary, with an increased susceptibility to A

Updated on:February 28,2024

Brain's 'speedometer' could help solve part of dementia puzzle

by University of ExeterCredit: Unsplash/CC0 Public DomainNearly one million people in the UK have dementia. People living with the most common form, Alzheimer's disease, can experience diffic

Updated on: May 18,2024

Brain's 'speedometer' could help solve part of dementia puzzle

by University of ExeterCredit: Unsplash/CC0 Public DomainNearly one million people in the UK have dementia. People living with the most common form, Alzheimer's disease, can experience diffic

Updated on:May 18,2024

Using tau imaging as diagnostic marker for Alzheimer disease

by The JAMA Network JournalsThe accumulation of β-Amyloid (Αβ) and tau proteins in the brain is hallmark pathology for Alzheimer disease. Recently developed positron emission tomography (PET) tra

Updated on: March 07,2024

Using tau imaging as diagnostic marker for Alzheimer disease

by The JAMA Network JournalsThe accumulation of β-Amyloid (Αβ) and tau proteins in the brain is hallmark pathology for Alzheimer disease. Recently developed positron emission tomography (PET) tra

Updated on:March 07,2024

Control of the iRhom2 protein may hold the key to preventing Alzheimer's disease

by CORDISCredit: IRHOM2 in ADIt is known that the onset of Alzheimer's disease (AD) is associated with the accumulation of Amyloid beta (Aβ) peptides in small molecular clusters known as olig

Updated on: March 09,2024

Control of the iRhom2 protein may hold the key to preventing Alzheimer's disease

by CORDISCredit: IRHOM2 in ADIt is known that the onset of Alzheimer's disease (AD) is associated with the accumulation of Amyloid beta (Aβ) peptides in small molecular clusters known as olig

Updated on:March 09,2024

Study unveils new insights into how neural stem cells are activated in the adult human brain

Updated on: February 28,2025

Study unveils new insights into how neural stem cells are activated in the adult human brain

Updated on:February 28,2025