Alzheimer's: New study supports amyloid hypothesis but suggests alternative treatment

by Columbia UniversityCREB3L2-ATF4 up-regulation in β-amyloid pathology 5xFAD model. In vivo detection and quantification of CREB3L2-ATF4 dimers by PLA in the dentate gyrus of 10-week-old 5xFAD o

Updated on: April 10,2024

Alzheimer's: New study supports amyloid hypothesis but suggests alternative treatment

by Columbia UniversityCREB3L2-ATF4 up-regulation in β-amyloid pathology 5xFAD model. In vivo detection and quantification of CREB3L2-ATF4 dimers by PLA in the dentate gyrus of 10-week-old 5xFAD o

Updated on:April 10,2024

Experimental Alzheimer's drug improves memory in mice

by Sarah C.p. Williams,University of California, Los AngelesCredit: CC0 Public DomainAn experimental drug known as A03, which was previously developed to treat depression, increases the levels o

Updated on: March 09,2024

Experimental Alzheimer's drug improves memory in mice

by Sarah C.p. Williams,University of California, Los AngelesCredit: CC0 Public DomainAn experimental drug known as A03, which was previously developed to treat depression, increases the levels o

Updated on:March 09,2024

Emergency/urgent hospitalizations linked to accelerated cognitive decline in older adults

by Rush University Medical CenterCredit: CC0 Public DomainEmergency and urgent hospitalizations are associated with an increased rate of cognitive decline in older adults, report researchers at R

Updated on: June 18,2024

Emergency/urgent hospitalizations linked to accelerated cognitive decline in older adults

by Rush University Medical CenterCredit: CC0 Public DomainEmergency and urgent hospitalizations are associated with an increased rate of cognitive decline in older adults, report researchers at R

Updated on:June 18,2024

New discovery for how the brain 'tangles' in Alzheimer's disease

by University of QueenslandCredit: Dr. Juan Polanco et. al., The University of Queensland.University of Queensland researchers have discovered a new 'seeding' process in brain cells that

Updated on: April 16,2024

New discovery for how the brain 'tangles' in Alzheimer's disease

by University of QueenslandCredit: Dr. Juan Polanco et. al., The University of Queensland.University of Queensland researchers have discovered a new 'seeding' process in brain cells that

Updated on:April 16,2024

Study reveals link between playing contact sports and parkinsonism in individuals with chronic traumatic encephalopathy

byBoston University School of MedicineCredit: Pixabay/CC0 Public DomainThe largest study of CTE to date has found a new link between playing contact sports, chronic traumatic encephalopathy (CTE

Updated on: July 17,2024

Study reveals link between playing contact sports and parkinsonism in individuals with chronic traumatic encephalopathy

byBoston University School of MedicineCredit: Pixabay/CC0 Public DomainThe largest study of CTE to date has found a new link between playing contact sports, chronic traumatic encephalopathy (CTE

Updated on:July 17,2024

Mesh-like scaffold is disordered in Alzheimer's-affected cells

by Will Sansom,University of Texas Health Science Center at San AntonioBrain cells from a fruit fly model of Alzheimer's disease were compared to healthy brain cells to show a type of dysfun

Updated on: February 27,2024

Mesh-like scaffold is disordered in Alzheimer's-affected cells

by Will Sansom,University of Texas Health Science Center at San AntonioBrain cells from a fruit fly model of Alzheimer's disease were compared to healthy brain cells to show a type of dysfun

Updated on:February 27,2024

Salt-seeking behavior traced to specific brain neurons

byUniversity of IowaCredit: Pixabay/CC0 Public DomainSalt, or more precisely the sodium it contains, is very much a "Goldilocks" nutrient. Low sodium levels cause a drop in blood volum

Updated on: January 19,2025

Salt-seeking behavior traced to specific brain neurons

byUniversity of IowaCredit: Pixabay/CC0 Public DomainSalt, or more precisely the sodium it contains, is very much a "Goldilocks" nutrient. Low sodium levels cause a drop in blood volum

Updated on:January 19,2025

Degrading modified proteins could treat Alzheimer's, other 'undruggable' diseases

by American Chemical SocietyGraphical abstract. Credit:ACS Central Science(2023). DOI: 10.1021/acscentsci.2c01369Certain diseases, including Alzheimer's, are currently considered

Updated on: June 24,2024

Degrading modified proteins could treat Alzheimer's, other 'undruggable' diseases

by American Chemical SocietyGraphical abstract. Credit:ACS Central Science(2023). DOI: 10.1021/acscentsci.2c01369Certain diseases, including Alzheimer's, are currently considered

Updated on:June 24,2024

Scientists discover a variation of the genome predisposing to Alzheimer's disease

by IDIBELL-Bellvitge Biomedical Research InstituteExample of cells of a patient with advanced Alzheimer's with an altered PM20D1 gene. Credit: IDIBELLAn article published inNature Medic

Updated on: March 09,2024

Scientists discover a variation of the genome predisposing to Alzheimer's disease

by IDIBELL-Bellvitge Biomedical Research InstituteExample of cells of a patient with advanced Alzheimer's with an altered PM20D1 gene. Credit: IDIBELLAn article published inNature Medic

Updated on:March 09,2024

Brain differences seen in young adults at genetic risk of Alzheimer's

by Amy Norton, Healthday ReporterGenetic risk for Alzheimer’s disease is linked to reduced grid-cell-like representations during virtual navigation. Credit: Created by bureaublauwgeel.nl, commissioned

Updated on: February 26,2024

Brain differences seen in young adults at genetic risk of Alzheimer's

by Amy Norton, Healthday ReporterGenetic risk for Alzheimer’s disease is linked to reduced grid-cell-like representations during virtual navigation. Credit: Created by bureaublauwgeel.nl, commissioned

Updated on:February 26,2024

Signs of Alzheimer's disease may be detectable before significant symptoms are obvious

by University of GlasgowCredit: Pixabay/CC0 Public DomainHealthy people with a higher genetic risk of Alzheimer's disease may show differences in brain structure and in cognitive test scores

Updated on: April 08,2024

Signs of Alzheimer's disease may be detectable before significant symptoms are obvious

by University of GlasgowCredit: Pixabay/CC0 Public DomainHealthy people with a higher genetic risk of Alzheimer's disease may show differences in brain structure and in cognitive test scores

Updated on:April 08,2024

New therapy may rapidly reverse life-changing sepsis-induced brain injury, animal study suggests

by Florey Institute of Neuroscience and Mental HealthCredit: Florey Institute of Neuroscience and Mental HealthFlorey researchers have shown that an extremely large "megadose" of sodium asco

Updated on: July 05,2024

New therapy may rapidly reverse life-changing sepsis-induced brain injury, animal study suggests

by Florey Institute of Neuroscience and Mental HealthCredit: Florey Institute of Neuroscience and Mental HealthFlorey researchers have shown that an extremely large "megadose" of sodium asco

Updated on:July 05,2024