Degrading modified proteins could treat Alzheimer's, other 'undruggable' diseases

by American Chemical SocietyGraphical abstract. Credit:ACS Central Science(2023). DOI: 10.1021/acscentsci.2c01369Certain diseases, including Alzheimer's, are currently considered

Updated on: June 24,2024 7

Degrading modified proteins could treat Alzheimer's, other 'undruggable' diseases

by American Chemical SocietyGraphical abstract. Credit:ACS Central Science(2023). DOI: 10.1021/acscentsci.2c01369Certain diseases, including Alzheimer's, are currently considered

Updated on:June 24,2024 7

Study finds no uniform brain shrinkage pattern in Alzheimer's

byUniversity College LondonMapped is the proportion of participants with a high rate of atrophy in cortical (left) and subcortical (right) areas. AD, Alzheimer's disease; MCI, mild cognitive

Updated on: October 16,2024 0

Study finds no uniform brain shrinkage pattern in Alzheimer's

byUniversity College LondonMapped is the proportion of participants with a high rate of atrophy in cortical (left) and subcortical (right) areas. AD, Alzheimer's disease; MCI, mild cognitive

Updated on:October 16,2024 0

Alzheimer's disease may cause vicious circle between brain network and immune cell dysfunctions

by Sarah C.p. Williams,Gladstone InstitutesA new study by Gladstone scientists suggests that certain anti-epileptic or tau-reducing treatments could be promising for people in the early stages o

Updated on: April 10,2024 20

Alzheimer's disease may cause vicious circle between brain network and immune cell dysfunctions

by Sarah C.p. Williams,Gladstone InstitutesA new study by Gladstone scientists suggests that certain anti-epileptic or tau-reducing treatments could be promising for people in the early stages o

Updated on:April 10,2024 20

Dietary fat alone does not cause changes in the hypothalamus, mouse study finds

by Deutsches Zentrum fuer Diabetesforschung DZDConfocal image representing the immunolabelling of AgRP and Synaptophysin-TdTomato in the paraventricular nucleus of the hypothalamus anterior (PVH ant)

Updated on: October 18,2024 0

Dietary fat alone does not cause changes in the hypothalamus, mouse study finds

by Deutsches Zentrum fuer Diabetesforschung DZDConfocal image representing the immunolabelling of AgRP and Synaptophysin-TdTomato in the paraventricular nucleus of the hypothalamus anterior (PVH ant)

Updated on:October 18,2024 0

New research shows that the heart has a mini-brain—its own nervous system that controls the heartbeat

byKarolinska InstitutetNeuroanatomy of the adult zebrafish intracardiac nervous system. Neuroanatomy of the adult zebrafish intracardiac nervous system. Credit:Nature Communications(

Updated on: December 18,2024 0

New research shows that the heart has a mini-brain—its own nervous system that controls the heartbeat

byKarolinska InstitutetNeuroanatomy of the adult zebrafish intracardiac nervous system. Neuroanatomy of the adult zebrafish intracardiac nervous system. Credit:Nature Communications(

Updated on:December 18,2024 0

Immune system dysfunction may occur early in Alzheimer's disease

by CU Anschutz Medical CampusPET scan of a human brain with Alzheimer's disease. Credit: public domainAn association between inflammation biomarkers in both blood plasma and cerebrospinal flu

Updated on: April 16,2024 10

Immune system dysfunction may occur early in Alzheimer's disease

by CU Anschutz Medical CampusPET scan of a human brain with Alzheimer's disease. Credit: public domainAn association between inflammation biomarkers in both blood plasma and cerebrospinal flu

Updated on:April 16,2024 10

Research reveals possible link between gastrointestinal syndromes and risk of brain aneurysm

by Society of NeuroInterventional SurgeryCredit: Pixabay/CC0 Public DomainThere is a potential connection between a diagnosis of certain gastrointestinal (GI) syndromes and the formation and rupture o

Updated on: July 31,2024 0

Research reveals possible link between gastrointestinal syndromes and risk of brain aneurysm

by Society of NeuroInterventional SurgeryCredit: Pixabay/CC0 Public DomainThere is a potential connection between a diagnosis of certain gastrointestinal (GI) syndromes and the formation and rupture o

Updated on:July 31,2024 0

Interactive app to assist rehabilitation of Alzheimer's patients

by Asociacion RUVIDTesting the Alzheimer's app prototype in the communityResearchers from the Polytechnic University of Valencia take their new Alzheimer's app out for first testing and f

Updated on: February 27,2024 14

Interactive app to assist rehabilitation of Alzheimer's patients

by Asociacion RUVIDTesting the Alzheimer's app prototype in the communityResearchers from the Polytechnic University of Valencia take their new Alzheimer's app out for first testing and f

Updated on:February 27,2024 14

Study explores how brain waves reflect melody predictions while listening to music

by Ingrid Fadelli , Medical XpressA, Snippet of the sets of regressors obtained from one piece of music used to calculate the TRFs. From top to bottom: acoustic envelope (Env), half-way rectified firs

Updated on: November 28,2024 0

Study explores how brain waves reflect melody predictions while listening to music

by Ingrid Fadelli , Medical XpressA, Snippet of the sets of regressors obtained from one piece of music used to calculate the TRFs. From top to bottom: acoustic envelope (Env), half-way rectified firs

Updated on:November 28,2024 0

Could 'zombie cells' in the skin be aging your brain too?

by Mayo Clinic News NetworkCredit: Pixabay/CC0 Public DomainMayo Clinic researchers have found that senescent cells—non-dividing "zombie" cells—accumulate in the skin as people age and may i

Updated on: November 06,2024 0

Could 'zombie cells' in the skin be aging your brain too?

by Mayo Clinic News NetworkCredit: Pixabay/CC0 Public DomainMayo Clinic researchers have found that senescent cells—non-dividing "zombie" cells—accumulate in the skin as people age and may i

Updated on:November 06,2024 0

Brain blood flow resistance more common in older adults with cognitive problems

byAmerican Physiological SocietyComparisons of cerebrovascular impedance coherence (top) and modulus (Z, bottom) between cognitive normal subjects (CN) and patients with amnestic mild cognitive

Updated on: November 05,2024 0

Brain blood flow resistance more common in older adults with cognitive problems

byAmerican Physiological SocietyComparisons of cerebrovascular impedance coherence (top) and modulus (Z, bottom) between cognitive normal subjects (CN) and patients with amnestic mild cognitive

Updated on:November 05,2024 0

New review suggests evaluating Tibetan medicinal herb as potential treatment for mild cognitive impairment

by Stephanie Baum , Medical XpressCredit:Frontiers in Pharmacology(2024). DOI: 10.3389/fphar.2024.1484040Within Tibetan medicine, the medicinal herb Terminalia chebula (T. chebula) is well

Updated on: November 07,2024 0

New review suggests evaluating Tibetan medicinal herb as potential treatment for mild cognitive impairment

by Stephanie Baum , Medical XpressCredit:Frontiers in Pharmacology(2024). DOI: 10.3389/fphar.2024.1484040Within Tibetan medicine, the medicinal herb Terminalia chebula (T. chebula) is well

Updated on:November 07,2024 0