Degrading modified proteins could treat Alzheimer's, other 'undruggable' diseases

by American Chemical SocietyGraphical abstract. Credit:ACS Central Science(2023). DOI: 10.1021/acscentsci.2c01369Certain diseases, including Alzheimer's, are currently considered

Updated on: June 24,2024

Degrading modified proteins could treat Alzheimer's, other 'undruggable' diseases

by American Chemical SocietyGraphical abstract. Credit:ACS Central Science(2023). DOI: 10.1021/acscentsci.2c01369Certain diseases, including Alzheimer's, are currently considered

Updated on:June 24,2024

Decoding sleep to reveal our state of health

by Bruno Geoffroy,University of MontrealA Schematic representation of the position of cannulas (in CA1) and electrodes (surface of the cerebral cortex) and timeline of the experimental protocol.

Updated on: March 28,2024

Decoding sleep to reveal our state of health

by Bruno Geoffroy,University of MontrealA Schematic representation of the position of cannulas (in CA1) and electrodes (surface of the cerebral cortex) and timeline of the experimental protocol.

Updated on:March 28,2024

Dementia creates listening issues in quiet, noisy environments

by Acoustical Society of AmericaCredit: CC0 Public DomainListening to the spoken word in noisy environments is challenging for everyone. Acoustic studies show people with mild dementia struggle t

Updated on: May 09,2024

Dementia creates listening issues in quiet, noisy environments

by Acoustical Society of AmericaCredit: CC0 Public DomainListening to the spoken word in noisy environments is challenging for everyone. Acoustic studies show people with mild dementia struggle t

Updated on:May 09,2024

A toxic byproduct of hemoglobin could provide treatments for Creutzfeldt-Jakob Disease

by Case Western Reserve UniversityScientists at Case Western Reserve University School of Medicine have identified a novel mechanism that could be used to protect the brain from damage due to str

Updated on: February 28,2024

A toxic byproduct of hemoglobin could provide treatments for Creutzfeldt-Jakob Disease

by Case Western Reserve UniversityScientists at Case Western Reserve University School of Medicine have identified a novel mechanism that could be used to protect the brain from damage due to str

Updated on:February 28,2024

Emergency/urgent hospitalizations linked to accelerated cognitive decline in older adults

by Rush University Medical CenterCredit: CC0 Public DomainEmergency and urgent hospitalizations are associated with an increased rate of cognitive decline in older adults, report researchers at R

Updated on: June 18,2024

Emergency/urgent hospitalizations linked to accelerated cognitive decline in older adults

by Rush University Medical CenterCredit: CC0 Public DomainEmergency and urgent hospitalizations are associated with an increased rate of cognitive decline in older adults, report researchers at R

Updated on:June 18,2024

Identifying health priorities early helps persons living with dementia

by Crystal Gwizdala,Yale UniversityCredit: Pixabay/CC0 Public DomainAs their disease progresses, persons living with dementia and multiple chronic conditions (MCC) increasingly rely on care part

Updated on: June 18,2024

Identifying health priorities early helps persons living with dementia

by Crystal Gwizdala,Yale UniversityCredit: Pixabay/CC0 Public DomainAs their disease progresses, persons living with dementia and multiple chronic conditions (MCC) increasingly rely on care part

Updated on:June 18,2024

Dementia prevention study signs up first recruit

by University of EdinburghJulie Duffus from near Edinburgh, Scotland, is the first participant to enrol in a major dementia prevention study led by the University of Edinburgh. Credit: Maverick P

Updated on: May 11,2024

Dementia prevention study signs up first recruit

by University of EdinburghJulie Duffus from near Edinburgh, Scotland, is the first participant to enrol in a major dementia prevention study led by the University of Edinburgh. Credit: Maverick P

Updated on:May 11,2024

White matter hyperintensities predate Alzheimer's onset

(HealthDay)—Autosomal dominant Alzheimer's disease is associated with increased white matter hyperintensities (WMH) on magnetic resonance imaging well before expected symptom onset, according to a

Updated on: February 28,2024

White matter hyperintensities predate Alzheimer's onset

(HealthDay)—Autosomal dominant Alzheimer's disease is associated with increased white matter hyperintensities (WMH) on magnetic resonance imaging well before expected symptom onset, according to a

Updated on:February 28,2024

Pimavanserin reduced symptoms of dementia-related psychosis in phase 3 trial

by University of ExeterA large-scale trial has found a treatment with pimavanserin substantially reduced psychotic symptoms and reduced risk of relapse of those symptoms compared to placebo in pe

Updated on: March 07,2024

Pimavanserin reduced symptoms of dementia-related psychosis in phase 3 trial

by University of ExeterA large-scale trial has found a treatment with pimavanserin substantially reduced psychotic symptoms and reduced risk of relapse of those symptoms compared to placebo in pe

Updated on:March 07,2024

Alzheimer's disease destroys neurons that keep us awake

by University of California, San FranciscoCredit: CC0 Public DomainResearchers and caregivers have noted that excessive daytime napping can develop long before the memory problems associated with

Updated on: April 10,2024

Alzheimer's disease destroys neurons that keep us awake

by University of California, San FranciscoCredit: CC0 Public DomainResearchers and caregivers have noted that excessive daytime napping can develop long before the memory problems associated with

Updated on:April 10,2024

Dementia spreads via connected brain networks

by University of California, San FranciscoCredit: CC0 Public DomainIn a new study, UC San Francisco scientists used maps of brain connections to predict how brain atrophy would spread in individu

Updated on: May 11,2024

Dementia spreads via connected brain networks

by University of California, San FranciscoCredit: CC0 Public DomainIn a new study, UC San Francisco scientists used maps of brain connections to predict how brain atrophy would spread in individu

Updated on:May 11,2024

Holiday stress can lead Alzheimer's patients and those with dementia to go missing

by Shelia PooleCredit: Pixabay/CC0 Public DomainHolidays are a time for families and friends to gather, but for older people with Alzheimer's disease and other dementias, it can cause so much stre

Updated on: February 01,2025

Holiday stress can lead Alzheimer's patients and those with dementia to go missing

by Shelia PooleCredit: Pixabay/CC0 Public DomainHolidays are a time for families and friends to gather, but for older people with Alzheimer's disease and other dementias, it can cause so much stre

Updated on:February 01,2025