Optogenetics approach reveals how alcohol use disorder impairs cognitive flexibility

by Danielle Michaud,Texas A&M UniversityExcessive alcohol intake reduces thalamically evoked burst-pause response in DMS CINs and impairs reversal of operant conditioning. Credit:Scien

Updated on: January 15,2025

Optogenetics approach reveals how alcohol use disorder impairs cognitive flexibility

by Danielle Michaud,Texas A&M UniversityExcessive alcohol intake reduces thalamically evoked burst-pause response in DMS CINs and impairs reversal of operant conditioning. Credit:Scien

Updated on:January 15,2025

Increased dementia risk in women—a matter of proteins?

by BioMed CentralGender-specific differences between the levels and structures of proteins present in the white matter and the mitochondria of the brains of men and women suffering from dementia

Updated on: February 28,2024

Increased dementia risk in women—a matter of proteins?

by BioMed CentralGender-specific differences between the levels and structures of proteins present in the white matter and the mitochondria of the brains of men and women suffering from dementia

Updated on:February 28,2024

Genetic variants linked to Alzheimer's trigger brain inflammation in females, preclinical study finds

byWeill Cornell Medical CollegeInflammatory microglia from afemalebrainin amouse model ofAlzheimer's disease. The mice also carry the APOE4 and TREM2 genetic ri

Updated on: October 09,2024

Genetic variants linked to Alzheimer's trigger brain inflammation in females, preclinical study finds

byWeill Cornell Medical CollegeInflammatory microglia from afemalebrainin amouse model ofAlzheimer's disease. The mice also carry the APOE4 and TREM2 genetic ri

Updated on:October 09,2024

Dementia perceived as "illness" rather than aging symptom can lower mood

by Louise Vennells,University of ExeterPeople who perceive dementia symptoms as an illness feel more negative than those who see it as an inevitable part of getting older, a new study indicates.

Updated on: February 28,2024

Dementia perceived as "illness" rather than aging symptom can lower mood

by Louise Vennells,University of ExeterPeople who perceive dementia symptoms as an illness feel more negative than those who see it as an inevitable part of getting older, a new study indicates.

Updated on:February 28,2024

Cheap, simple tests could improve Alzheimer's disease management at the bedside

by ElsevierA portable biosensor that could show how disease is progressing in patients with Alzheimer's could greatly improve people's quality of life in the future, according to a new re

Updated on: February 28,2024

Cheap, simple tests could improve Alzheimer's disease management at the bedside

by ElsevierA portable biosensor that could show how disease is progressing in patients with Alzheimer's could greatly improve people's quality of life in the future, according to a new re

Updated on:February 28,2024

Neural circuits reveal new insights into how we navigate space and store memories

by Pat Harriman,University of California, IrvineDistinct RSC neuronal circuits corresponding to M2- and AD-projection neurons revealed by retrograde adeno-associated (rAAV2-retro) virus and ante

Updated on: November 28,2024

Neural circuits reveal new insights into how we navigate space and store memories

by Pat Harriman,University of California, IrvineDistinct RSC neuronal circuits corresponding to M2- and AD-projection neurons revealed by retrograde adeno-associated (rAAV2-retro) virus and ante

Updated on:November 28,2024

Experimental study in rats and humans show cognitive effort whets the appetite for reward

by PNAS NexusEffects of cognitive effort without rest on cocaine self-administration. Experimental design (A), time course (B) and average in the last 3 days of self-administration (C) of number of in

Updated on: November 07,2024

Experimental study in rats and humans show cognitive effort whets the appetite for reward

by PNAS NexusEffects of cognitive effort without rest on cocaine self-administration. Experimental design (A), time course (B) and average in the last 3 days of self-administration (C) of number of in

Updated on:November 07,2024

Hippocampus study shows chronic pain can be predicted within three days of whiplash injury

byNorthwestern UniversityHippocampal head, body, and tail seeds were defined from the hippocampal parcellation of ref, and target hippocampal network ROIs were defined using the Harvard–Oxford C

Updated on: November 06,2024

Hippocampus study shows chronic pain can be predicted within three days of whiplash injury

byNorthwestern UniversityHippocampal head, body, and tail seeds were defined from the hippocampal parcellation of ref, and target hippocampal network ROIs were defined using the Harvard–Oxford C

Updated on:November 06,2024

Stroke associated with accelerated long-term cognitive decline

by Helena Hudson,University of New South WalesCredit: Pixabay/CC0 Public DomainNew evidence from the Centre for Healthy Brain Ageing (CHeBA) indicates that older adults who experience a stroke f

Updated on: October 21,2024

Stroke associated with accelerated long-term cognitive decline

by Helena Hudson,University of New South WalesCredit: Pixabay/CC0 Public DomainNew evidence from the Centre for Healthy Brain Ageing (CHeBA) indicates that older adults who experience a stroke f

Updated on:October 21,2024

Skin may hold key to neurodevelopmental disorder diagnoses

by Rhiannon Koch,University of AdelaideCredit:The American Journal of Human Genetics(2024). DOI: 10.1016/j.ajhg.2024.06.018A genetic diagnostic method using a small sample of skin fr

Updated on: August 08,2024

Skin may hold key to neurodevelopmental disorder diagnoses

by Rhiannon Koch,University of AdelaideCredit:The American Journal of Human Genetics(2024). DOI: 10.1016/j.ajhg.2024.06.018A genetic diagnostic method using a small sample of skin fr

Updated on:August 08,2024

Hearing loss linked to early memory and thinking problems

by Alzheimer's Research UKResearchers at the Alzheimer's Association International Conference 2017 have suggested that people with a family history of Alzheimer's disease who experien

Updated on: March 07,2024

Hearing loss linked to early memory and thinking problems

by Alzheimer's Research UKResearchers at the Alzheimer's Association International Conference 2017 have suggested that people with a family history of Alzheimer's disease who experien

Updated on:March 07,2024

Gene variant could protect against ultra-rare seizure disorder, fruit fly research finds

byUniversity of Utah Health SciencesFruit flies for research purposes in a vial in lab. Credit: Charlie Ehlert / University of Utah HealthOne in 10 Americans live with a rare disease, which ofte

Updated on: February 18,2025

Gene variant could protect against ultra-rare seizure disorder, fruit fly research finds

byUniversity of Utah Health SciencesFruit flies for research purposes in a vial in lab. Credit: Charlie Ehlert / University of Utah HealthOne in 10 Americans live with a rare disease, which ofte

Updated on:February 18,2025