Gene editing tool reduces Alzheimer's plaque precursor in mice

by Liz Ahlberg Touchstone,University of Illinois at Urbana-ChampaignSimultaneous editing of splice sites with SPLICER enhances exon skipping. Credit:Nature Communications(2024). DOI:

Updated on: January 08,2025

Gene editing tool reduces Alzheimer's plaque precursor in mice

by Liz Ahlberg Touchstone,University of Illinois at Urbana-ChampaignSimultaneous editing of splice sites with SPLICER enhances exon skipping. Credit:Nature Communications(2024). DOI:

Updated on:January 08,2025

Researchers mark milestone in progress toward investigational new drug for triple-negative breast cancer

by Leslie Cantu,Medical University of South CarolinaDr. Ozgur Sahin, center, with first authors Drs. Ozge Saatci and Metin Cetin. Credit: MUSC Hollings Cancer CenterA new compound developed by r

Updated on: August 01,2024

Researchers mark milestone in progress toward investigational new drug for triple-negative breast cancer

by Leslie Cantu,Medical University of South CarolinaDr. Ozgur Sahin, center, with first authors Drs. Ozge Saatci and Metin Cetin. Credit: MUSC Hollings Cancer CenterA new compound developed by r

Updated on:August 01,2024

No reduction in death or severe brain injury with cerebral oximetry monitoring in extremely preterm infants, finds study

by Justin Jackson , Medical XpressCredit: Unsplash/CC0 Public DomainAn international team of 100 researchers at 70 sites in 17 countries has found no reduction in death for treatment guided by cerebra

Updated on: May 13,2024

No reduction in death or severe brain injury with cerebral oximetry monitoring in extremely preterm infants, finds study

by Justin Jackson , Medical XpressCredit: Unsplash/CC0 Public DomainAn international team of 100 researchers at 70 sites in 17 countries has found no reduction in death for treatment guided by cerebra

Updated on:May 13,2024

Alzheimer's: New study supports amyloid hypothesis but suggests alternative treatment

by Columbia UniversityCREB3L2-ATF4 up-regulation in β-amyloid pathology 5xFAD model. In vivo detection and quantification of CREB3L2-ATF4 dimers by PLA in the dentate gyrus of 10-week-old 5xFAD o

Updated on: April 10,2024

Alzheimer's: New study supports amyloid hypothesis but suggests alternative treatment

by Columbia UniversityCREB3L2-ATF4 up-regulation in β-amyloid pathology 5xFAD model. In vivo detection and quantification of CREB3L2-ATF4 dimers by PLA in the dentate gyrus of 10-week-old 5xFAD o

Updated on:April 10,2024

Right under your nose: A more convenient way to diagnose Alzheimer's disease

by Daegu Gyeongbuk Institute of Science and TechnologyCredit: CC0 Public DomainScientists from the Daegu Gyeongbuk Institute of Science and Technology, Republic of Korea, have discovered a new way to

Updated on: July 04,2024

Right under your nose: A more convenient way to diagnose Alzheimer's disease

by Daegu Gyeongbuk Institute of Science and TechnologyCredit: CC0 Public DomainScientists from the Daegu Gyeongbuk Institute of Science and Technology, Republic of Korea, have discovered a new way to

Updated on:July 04,2024

Can older adults with dementia continue to drive? More study is needed

by American Geriatrics SocietyHow do you know when it's time for an older adult with mild dementia to stop driving? Dementia is a general term for a decline in mental ability severe enough to inte

Updated on: March 07,2024

Can older adults with dementia continue to drive? More study is needed

by American Geriatrics SocietyHow do you know when it's time for an older adult with mild dementia to stop driving? Dementia is a general term for a decline in mental ability severe enough to inte

Updated on:March 07,2024

New template of the human brain enhances neuroimaging data analysis

byDartmouth CollegeVariation in vertex properties across the cortex.a, The distribution of vertices in fsavg, fslr and onavg, as measured by inter-vertex distance.b, Standard deviati

Updated on: July 17,2024

New template of the human brain enhances neuroimaging data analysis

byDartmouth CollegeVariation in vertex properties across the cortex.a, The distribution of vertices in fsavg, fslr and onavg, as measured by inter-vertex distance.b, Standard deviati

Updated on:July 17,2024

Skin may hold key to neurodevelopmental disorder diagnoses

by Rhiannon Koch,University of AdelaideCredit:The American Journal of Human Genetics(2024). DOI: 10.1016/j.ajhg.2024.06.018A genetic diagnostic method using a small sample of skin fr

Updated on: August 08,2024

Skin may hold key to neurodevelopmental disorder diagnoses

by Rhiannon Koch,University of AdelaideCredit:The American Journal of Human Genetics(2024). DOI: 10.1016/j.ajhg.2024.06.018A genetic diagnostic method using a small sample of skin fr

Updated on:August 08,2024

Those with stroke risk factors may be more likely to have severe strokes

byAmerican Academy of NeurologyCredit: Pixabay/CC0 Public DomainPeople with conditions or habits such as high blood pressure, an irregular heartbeat called atrial fibrillation, or smoking, not o

Updated on: November 28,2024

Those with stroke risk factors may be more likely to have severe strokes

byAmerican Academy of NeurologyCredit: Pixabay/CC0 Public DomainPeople with conditions or habits such as high blood pressure, an irregular heartbeat called atrial fibrillation, or smoking, not o

Updated on:November 28,2024

Diabetes drug could influence brain activity in Alzheimer's

by Alzheimer's Research UKResearchers in Denmark have released findings from a small clinical trial of the diabetes drug liraglutide in people living with Alzheimer's disease.Thepil

Updated on: February 28,2024

Diabetes drug could influence brain activity in Alzheimer's

by Alzheimer's Research UKResearchers in Denmark have released findings from a small clinical trial of the diabetes drug liraglutide in people living with Alzheimer's disease.Thepil

Updated on:February 28,2024

Micro-needle insertion into hippocampus helps brain regeneration in animal model of Alzheimer's disease

by Cell Transplantation Center of Excellence for Aging and Brain RepairResearchers testing the potential positive effects of "micro-injury" by brief insertion of a small needle into the hipp

Updated on: February 28,2024

Micro-needle insertion into hippocampus helps brain regeneration in animal model of Alzheimer's disease

by Cell Transplantation Center of Excellence for Aging and Brain RepairResearchers testing the potential positive effects of "micro-injury" by brief insertion of a small needle into the hipp

Updated on:February 28,2024

Study of patients with epilepsy shows how making new neurons benefits cognition

byKeck School of Medicine of USCNewborn neuron (green and purple cell) in brain tissue from patients with epilepsy. Credit: Aswathy Ammothumkandy/Bonaguidi Lab/USC.Cell Stem CellWhy do adu

Updated on: December 17,2024

Study of patients with epilepsy shows how making new neurons benefits cognition

byKeck School of Medicine of USCNewborn neuron (green and purple cell) in brain tissue from patients with epilepsy. Credit: Aswathy Ammothumkandy/Bonaguidi Lab/USC.Cell Stem CellWhy do adu

Updated on:December 17,2024