Alzheimer's: New study supports amyloid hypothesis but suggests alternative treatment

by Columbia UniversityCREB3L2-ATF4 up-regulation in β-amyloid pathology 5xFAD model. In vivo detection and quantification of CREB3L2-ATF4 dimers by PLA in the dentate gyrus of 10-week-old 5xFAD o

Updated on: April 10,2024

Alzheimer's: New study supports amyloid hypothesis but suggests alternative treatment

by Columbia UniversityCREB3L2-ATF4 up-regulation in β-amyloid pathology 5xFAD model. In vivo detection and quantification of CREB3L2-ATF4 dimers by PLA in the dentate gyrus of 10-week-old 5xFAD o

Updated on:April 10,2024

Rehabilitation approach combines spinal and hip stimulation to improve walking speed in patients with stroke

Updated on: September 02,2025

Rehabilitation approach combines spinal and hip stimulation to improve walking speed in patients with stroke

Updated on:September 02,2025

Hope for Alzheimer's blood test

by Macquarie UniversityBoxplots comparing plasma Aβ1-42/Aβ1-40 ratio, p-tau181, GFAP, and NfL between CU Aβ−, CU Aβ+, MCI Aβ−, MCI Aβ+, and AD Aβ+ groups at timepoint 1. Plasma measures were comp

Updated on: March 30,2024

Hope for Alzheimer's blood test

by Macquarie UniversityBoxplots comparing plasma Aβ1-42/Aβ1-40 ratio, p-tau181, GFAP, and NfL between CU Aβ−, CU Aβ+, MCI Aβ−, MCI Aβ+, and AD Aβ+ groups at timepoint 1. Plasma measures were comp

Updated on:March 30,2024

Identification of a central regulator

by Ludwig Maximilian University of MunichC1q (green) and ApoE (red) proteins form deposits in the choroid plexus, as the researchers revealed by super-resolution microscopy. Bar 1 µm. Credit: C.

Updated on: March 09,2024

Identification of a central regulator

by Ludwig Maximilian University of MunichC1q (green) and ApoE (red) proteins form deposits in the choroid plexus, as the researchers revealed by super-resolution microscopy. Bar 1 µm. Credit: C.

Updated on:March 09,2024

Can older adults with dementia continue to drive? More study is needed

by American Geriatrics SocietyHow do you know when it's time for an older adult with mild dementia to stop driving? Dementia is a general term for a decline in mental ability severe enough to inte

Updated on: March 07,2024

Can older adults with dementia continue to drive? More study is needed

by American Geriatrics SocietyHow do you know when it's time for an older adult with mild dementia to stop driving? Dementia is a general term for a decline in mental ability severe enough to inte

Updated on:March 07,2024

New template of the human brain enhances neuroimaging data analysis

byDartmouth CollegeVariation in vertex properties across the cortex.a, The distribution of vertices in fsavg, fslr and onavg, as measured by inter-vertex distance.b, Standard deviati

Updated on: July 17,2024

New template of the human brain enhances neuroimaging data analysis

byDartmouth CollegeVariation in vertex properties across the cortex.a, The distribution of vertices in fsavg, fslr and onavg, as measured by inter-vertex distance.b, Standard deviati

Updated on:July 17,2024

How 40Hz sensory gamma rhythm stimulation clears amyloid in Alzheimer's mice

by Massachusetts Institute of TechnologyBright staining highlights VIP-expressing interneurons in this coronal cross-section of a mouse brain. The neurons may help drive glymphatic clearance of a

Updated on: March 08,2024

How 40Hz sensory gamma rhythm stimulation clears amyloid in Alzheimer's mice

by Massachusetts Institute of TechnologyBright staining highlights VIP-expressing interneurons in this coronal cross-section of a mouse brain. The neurons may help drive glymphatic clearance of a

Updated on:March 08,2024

Gene editing tool reduces Alzheimer's plaque precursor in mice

by Liz Ahlberg Touchstone,University of Illinois at Urbana-ChampaignSimultaneous editing of splice sites with SPLICER enhances exon skipping. Credit:Nature Communications(2024). DOI:

Updated on: January 08,2025

Gene editing tool reduces Alzheimer's plaque precursor in mice

by Liz Ahlberg Touchstone,University of Illinois at Urbana-ChampaignSimultaneous editing of splice sites with SPLICER enhances exon skipping. Credit:Nature Communications(2024). DOI:

Updated on:January 08,2025

Gut microbiome changes linked to multiple sclerosis, study finds

Updated on: March 25,2025

Gut microbiome changes linked to multiple sclerosis, study finds

Updated on:March 25,2025

Scientists highlight negative impacts of sleep disruption on early brain development

byUniversity of North Carolina at Chapel Hill School of MedicineCredit: CC0 Public DomainSleep deprivation in adults has long been proven to cause long-term mental and physical health issues, in

Updated on: November 07,2024

Scientists highlight negative impacts of sleep disruption on early brain development

byUniversity of North Carolina at Chapel Hill School of MedicineCredit: CC0 Public DomainSleep deprivation in adults has long been proven to cause long-term mental and physical health issues, in

Updated on:November 07,2024

Alzheimer's more versatile than previously known

by Lund UniversityThe illuminated spotes (red, yellow and green) indicate an accumulation of the protein beta-amyloid. The top row shows the brain of a patient diagnosed with Alzheimer's dise

Updated on: February 28,2024

Alzheimer's more versatile than previously known

by Lund UniversityThe illuminated spotes (red, yellow and green) indicate an accumulation of the protein beta-amyloid. The top row shows the brain of a patient diagnosed with Alzheimer's dise

Updated on:February 28,2024

Study of older people shows lower risk of dementia with higher levels of apolipoprotein E in HDL

by Bob Yirka , Medical XpressA team of researchers affiliated with multiple institutions across the U.S. has found that older people who have heightened levels of apolipoprotein E in their high-densit

Updated on: March 07,2024

Study of older people shows lower risk of dementia with higher levels of apolipoprotein E in HDL

by Bob Yirka , Medical XpressA team of researchers affiliated with multiple institutions across the U.S. has found that older people who have heightened levels of apolipoprotein E in their high-densit

Updated on:March 07,2024