A therapeutic target for Alzheimer's disease discovered

by Laval UniversityFRET ratio is independent of laser intensity, and imaging depth was comparable between NonTg and 5xFAD mice. (A) Confocal image of the AAV2/9.CaMKIIa.SuperClomeleon (SCLM) infe

Updated on: May 28,2024 8

A therapeutic target for Alzheimer's disease discovered

by Laval UniversityFRET ratio is independent of laser intensity, and imaging depth was comparable between NonTg and 5xFAD mice. (A) Confocal image of the AAV2/9.CaMKIIa.SuperClomeleon (SCLM) infe

Updated on:May 28,2024 8

Alzheimer's disease could be treated with gene therapy, animal study suggests

by Imperial College LondonBrain cells from a mouse cortex that didn't receive the gene therapy. The amyloid plaques are shown in green, and the glial cells, which surround the plaques, are sh

Updated on: May 22,2024 4

Alzheimer's disease could be treated with gene therapy, animal study suggests

by Imperial College LondonBrain cells from a mouse cortex that didn't receive the gene therapy. The amyloid plaques are shown in green, and the glial cells, which surround the plaques, are sh

Updated on:May 22,2024 4

High risk for psychiatric disorders seen before dementia diagnosis

by Lori SolomonPatients with dementia have markedly increased risks for psychiatric disorders before dementia diagnosis, according to a study published online Oct. 17 inJAMA Network Open.Minjia

Updated on: February 24,2024 13

High risk for psychiatric disorders seen before dementia diagnosis

by Lori SolomonPatients with dementia have markedly increased risks for psychiatric disorders before dementia diagnosis, according to a study published online Oct. 17 inJAMA Network Open.Minjia

Updated on:February 24,2024 13

Finding epilepsy hotspots before surgery: A faster, non-invasive approach

by Nancy Fliesler,Children's Hospital BostonCredit: Pixabay/CC0 Public DomainNeurosurgery for patients with drug-resistant epilepsy requires locating the precise brain areas that are generat

Updated on: September 09,2024 0

Finding epilepsy hotspots before surgery: A faster, non-invasive approach

by Nancy Fliesler,Children's Hospital BostonCredit: Pixabay/CC0 Public DomainNeurosurgery for patients with drug-resistant epilepsy requires locating the precise brain areas that are generat

Updated on:September 09,2024 0

Stalked by the fear that dementia is stalking you

by Judith GrahamCredit: CC0 Public DomainDo I know I'm at risk for developing dementia? You bet.My father died of Alzheimer's disease at age 72; my sister was felled byfrontotemporal dem

Updated on: April 29,2024 14

Stalked by the fear that dementia is stalking you

by Judith GrahamCredit: CC0 Public DomainDo I know I'm at risk for developing dementia? You bet.My father died of Alzheimer's disease at age 72; my sister was felled byfrontotemporal dem

Updated on:April 29,2024 14

Black patients face delays in Alzheimer's diagnosis, research finds

by Radiological Society of North AmericaBrain MRI images. Credit: RSNA/Joshua Wibecan, M.D.Black patients underwent medical imaging for cognitive impairment years later than white and Hispanic pa

Updated on: February 24,2024 18

Black patients face delays in Alzheimer's diagnosis, research finds

by Radiological Society of North AmericaBrain MRI images. Credit: RSNA/Joshua Wibecan, M.D.Black patients underwent medical imaging for cognitive impairment years later than white and Hispanic pa

Updated on:February 24,2024 18

New memory drug moves into Phase 1 clinical study

by National Institutes of HealthAn experimental drug that may improve memory is now being tested in a Phase 1 safety trial. The compound, BPN14770, was developed by Tetra Discovery Partners, with

Updated on: February 27,2024 16

New memory drug moves into Phase 1 clinical study

by National Institutes of HealthAn experimental drug that may improve memory is now being tested in a Phase 1 safety trial. The compound, BPN14770, was developed by Tetra Discovery Partners, with

Updated on:February 27,2024 16

Surgery-free brain stimulation could provide new treatment for dementia

by Ryan O'Hare,Imperial College LondonTemporal interference (TI) is non-invasive and delivers electrical stimulation through electrodes placed on the participant's head. Credit: Imperial

Updated on: January 12,2024 17

Surgery-free brain stimulation could provide new treatment for dementia

by Ryan O'Hare,Imperial College LondonTemporal interference (TI) is non-invasive and delivers electrical stimulation through electrodes placed on the participant's head. Credit: Imperial

Updated on:January 12,2024 17

Attention and memory deficits persist for months after recovery from mild COVID

by University of OxfordGraphical abstract. Credit: DOI: 10.1093/braincomms/fcab295Researchers from Oxford's Department of Experimental Psychology and Nuffield Department of Clinical Neuroscie

Updated on: February 18,2024 5

Attention and memory deficits persist for months after recovery from mild COVID

by University of OxfordGraphical abstract. Credit: DOI: 10.1093/braincomms/fcab295Researchers from Oxford's Department of Experimental Psychology and Nuffield Department of Clinical Neuroscie

Updated on:February 18,2024 5

Silence for thought: Special interneuron networks in the human brain

by Max Planck SocietyHuman neuronal networks, mapped from different parts of the cerebral cortex. Connectomic comparison to mouse revealed massively expanded interneuron-to-interneuron networks i

Updated on: February 05,2024 19

Silence for thought: Special interneuron networks in the human brain

by Max Planck SocietyHuman neuronal networks, mapped from different parts of the cerebral cortex. Connectomic comparison to mouse revealed massively expanded interneuron-to-interneuron networks i

Updated on:February 05,2024 19

Alzheimer's drug donanemab has been hailed as a turning point. But what does it mean for people with the disease?

by Steve Macfarlane,The ConversationCredit: AI-generated imageTrial results of a new drug to treat Alzheimer's disease, donanemab, shows it canslow cognitive declineby 35%. The d

Updated on: April 16,2024 18

Alzheimer's drug donanemab has been hailed as a turning point. But what does it mean for people with the disease?

by Steve Macfarlane,The ConversationCredit: AI-generated imageTrial results of a new drug to treat Alzheimer's disease, donanemab, shows it canslow cognitive declineby 35%. The d

Updated on:April 16,2024 18

New study identifies gene believed to be responsible for ALS and dementia

byCase Western Reserve UniversityRepresentative human spinal cord tissue imaged at 4X objective for DAPI (blue), CD80 (red), and Iba1 (green) from an C9ORF72 ALS case and a non-ALS control. Scal

Updated on: April 26,2024 0

New study identifies gene believed to be responsible for ALS and dementia

byCase Western Reserve UniversityRepresentative human spinal cord tissue imaged at 4X objective for DAPI (blue), CD80 (red), and Iba1 (green) from an C9ORF72 ALS case and a non-ALS control. Scal

Updated on:April 26,2024 0