Immune cells identified as key players in brain health

byThe Mount Sinai HospitalThe Icahn Mount Sinai researchers nominated and validated transcription factors BHLHE40 and BHLHE41 that regulate clearance processes in immune cells, including brain i

Updated on: March 27,2024

Immune cells identified as key players in brain health

byThe Mount Sinai HospitalThe Icahn Mount Sinai researchers nominated and validated transcription factors BHLHE40 and BHLHE41 that regulate clearance processes in immune cells, including brain i

Updated on:March 27,2024

Specialized motor neuron region affected in amyotrophic lateral sclerosis, new study finds

byKing's College LondonCredit:Cell Reports(2023). DOI: 10.1016/j.celrep.2023.113509A new study,publishedinCell Reports, reports a novel mechanism behind dysregu

Updated on: April 09,2024

Specialized motor neuron region affected in amyotrophic lateral sclerosis, new study finds

byKing's College LondonCredit:Cell Reports(2023). DOI: 10.1016/j.celrep.2023.113509A new study,publishedinCell Reports, reports a novel mechanism behind dysregu

Updated on:April 09,2024

Gene mutation may speed up memory loss in Alzheimer's disease

by American Academy of NeurologyDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.A gene mutation may accelerate the loss of memory and thinking skill

Updated on: June 14,2024

Gene mutation may speed up memory loss in Alzheimer's disease

by American Academy of NeurologyDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.A gene mutation may accelerate the loss of memory and thinking skill

Updated on:June 14,2024

Machine-learning program reveals genes responsible for sex-specific differences in Alzheimer's disease progression

by Texas Children's HospitalThe top 98 EAML genes are connected to GWAS genes, dysregulated in AD patients, and capable of separating AD and healthy control samples. Credit:Nature Commu

Updated on: June 11,2024

Machine-learning program reveals genes responsible for sex-specific differences in Alzheimer's disease progression

by Texas Children's HospitalThe top 98 EAML genes are connected to GWAS genes, dysregulated in AD patients, and capable of separating AD and healthy control samples. Credit:Nature Commu

Updated on:June 11,2024

New studies suggest millions with mild cognitive impairment go undiagnosed, often until it's too late

by Soeren Mattke and Ying Liu,The ConversationCredit: Pixabay/CC0 Public DomainMild cognitive impairment—an early stage of dementia—is widely underdiagnosed in people 65 and older. That is the k

Updated on: March 28,2024

New studies suggest millions with mild cognitive impairment go undiagnosed, often until it's too late

by Soeren Mattke and Ying Liu,The ConversationCredit: Pixabay/CC0 Public DomainMild cognitive impairment—an early stage of dementia—is widely underdiagnosed in people 65 and older. That is the k

Updated on:March 28,2024

Aβ43 generation in familial Alzheimer's disease: New insights into disease onset

by Doshisha UniversityIn this study, γ-secretase was extracted from wild type (WT) cells and cells carrying FAD-related genetic mutations (mutations in presenilin 1: L85P, I143T, H163R, L166P, G206V,

Updated on: June 20,2024

Aβ43 generation in familial Alzheimer's disease: New insights into disease onset

by Doshisha UniversityIn this study, γ-secretase was extracted from wild type (WT) cells and cells carrying FAD-related genetic mutations (mutations in presenilin 1: L85P, I143T, H163R, L166P, G206V,

Updated on:June 20,2024

A new drug could turn back the clock on multiple sclerosis

byUniversity of California, San FranciscoM1R+OPCs are present in rat and human brain tissue sections. Credit:Proceedings of the National Academy of Sciences(2024). DOI: 10.1073

Updated on: August 26,2024

A new drug could turn back the clock on multiple sclerosis

byUniversity of California, San FranciscoM1R+OPCs are present in rat and human brain tissue sections. Credit:Proceedings of the National Academy of Sciences(2024). DOI: 10.1073

Updated on:August 26,2024

Study: Age-related alterations in the oscillatory dynamics serving verbal working memory processing

by Impact Journals LLCEffect of age on alpha and beta oscillations during the encoding, maintenance, and retrieval phases. Credit: 2023 Springer et al.A new research paper was published on the cover o

Updated on: January 09,2024

Study: Age-related alterations in the oscillatory dynamics serving verbal working memory processing

by Impact Journals LLCEffect of age on alpha and beta oscillations during the encoding, maintenance, and retrieval phases. Credit: 2023 Springer et al.A new research paper was published on the cover o

Updated on:January 09,2024

Attention and memory deficits persist for months after recovery from mild COVID

by University of OxfordGraphical abstract. Credit: DOI: 10.1093/braincomms/fcab295Researchers from Oxford's Department of Experimental Psychology and Nuffield Department of Clinical Neuroscie

Updated on: February 18,2024

Attention and memory deficits persist for months after recovery from mild COVID

by University of OxfordGraphical abstract. Credit: DOI: 10.1093/braincomms/fcab295Researchers from Oxford's Department of Experimental Psychology and Nuffield Department of Clinical Neuroscie

Updated on:February 18,2024

COVID-19 sees prescriptions increase for dementia drugs linked with serious side-effects

by Alzheimer's Research UKCredit: CC0 Public DomainNew research published inThe Lancetonline finds that not only are dementia deaths up 79% (ONS figures—19th Oct) compared to prev

Updated on: March 26,2024

COVID-19 sees prescriptions increase for dementia drugs linked with serious side-effects

by Alzheimer's Research UKCredit: CC0 Public DomainNew research published inThe Lancetonline finds that not only are dementia deaths up 79% (ONS figures—19th Oct) compared to prev

Updated on:March 26,2024

Gold nanoclusters: New frontier for developing medication for treatment of Alzheimer's disease

by Science China PressAu23(CR)14 Nanocluster functions in multiple stages of the progression from Aβ monomer to Aβ plaques. Credit: ©Science China PressAlzheimer's disease (AD) is a progressi

Updated on: July 01,2024

Gold nanoclusters: New frontier for developing medication for treatment of Alzheimer's disease

by Science China PressAu23(CR)14 Nanocluster functions in multiple stages of the progression from Aβ monomer to Aβ plaques. Credit: ©Science China PressAlzheimer's disease (AD) is a progressi

Updated on:July 01,2024

Researchers map converging trajectories of cognitive development through adolescence

byUniversity of PittsburghScaled domain general executive function scores generate reproducible adolescent growth charts across datasets and tasks. Accuracy (A) and latency (B) composite (z scor

Updated on: January 12,2024

Researchers map converging trajectories of cognitive development through adolescence

byUniversity of PittsburghScaled domain general executive function scores generate reproducible adolescent growth charts across datasets and tasks. Accuracy (A) and latency (B) composite (z scor

Updated on:January 12,2024