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Breakthroughs
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Researchers advance understanding of Parkinson's disease

Researchers advance understanding of Parkinson's disease

byUniversity of GalwaySchematic representation of the experimental design and procedures followed in this study. The study was designed for the region-specific and temporal characterization of t

Researchers advance understanding of Parkinson's disease

byUniversity of GalwaySchematic representation of the experimental design and procedures followed in this study. The study was designed for the region-specific and temporal characterization of t
Precursor of cholesterol protects cells from ferroptosis, study finds

Precursor of cholesterol protects cells from ferroptosis, study finds

JANUARY 31, 2024byUniversity of WürzburgSpace-filling model of the Cholesterol molecule. Credit: RedAndr/WikipediaIn a groundbreaking study, a team led by Würzburg Professor José Pedro Friedmann

Precursor of cholesterol protects cells from ferroptosis, study finds

JANUARY 31, 2024byUniversity of WürzburgSpace-filling model of the Cholesterol molecule. Credit: RedAndr/WikipediaIn a groundbreaking study, a team led by Würzburg Professor José Pedro Friedmann
New approach to the design of therapies that enhance the effect of cholesterol-lowering drugs

New approach to the design of therapies that enhance the effect of cholesterol-lowering drugs

FEBRUARY 1, 2024by Centro Nacional de Investigaciones Cardiovasculares Carlos III (F.S.P.)Graphical summary. Credit:Nature Cardiovascular Research(2024). DOI: 10.1038/s44161-023-00412-wA r

New approach to the design of therapies that enhance the effect of cholesterol-lowering drugs

FEBRUARY 1, 2024by Centro Nacional de Investigaciones Cardiovasculares Carlos III (F.S.P.)Graphical summary. Credit:Nature Cardiovascular Research(2024). DOI: 10.1038/s44161-023-00412-wA r
Study highlights impact of aldehydes on DNA damage and aging

Study highlights impact of aldehydes on DNA damage and aging

byNagoya UniversityHistones are crosslinked with DNA (histone-DPC) following formaldehyde exposure, leading to the malfunction of cellular processes such as transcription. Credit: Reiko Matsushi

Study highlights impact of aldehydes on DNA damage and aging

byNagoya UniversityHistones are crosslinked with DNA (histone-DPC) following formaldehyde exposure, leading to the malfunction of cellular processes such as transcription. Credit: Reiko Matsushi
New findings suggest life span can be increased by making cells less efficient at producing energy

New findings suggest life span can be increased by making cells less efficient at producing energy

by Pennington Biomedical Research CenterChristopher Axelrod, Director, Integrated Physiology and Molecular Medicine Laboratory at Pennington Biomedical Research Center. Credit: PBRCA newstudy&nb

New findings suggest life span can be increased by making cells less efficient at producing energy

by Pennington Biomedical Research CenterChristopher Axelrod, Director, Integrated Physiology and Molecular Medicine Laboratory at Pennington Biomedical Research Center. Credit: PBRCA newstudy&nb
Key mechanism governing bone marrow stem cells opens door to new therapies

Key mechanism governing bone marrow stem cells opens door to new therapies

by King's College LondonCredit: Pixabay/CC0 Public DomainA key mechanism controlling how bone marrow stem cells work has been revealed in a new study, shining a light on the principles of ste

Key mechanism governing bone marrow stem cells opens door to new therapies

by King's College LondonCredit: Pixabay/CC0 Public DomainA key mechanism controlling how bone marrow stem cells work has been revealed in a new study, shining a light on the principles of ste
Researchers define new subtypes of common brain disorder

Researchers define new subtypes of common brain disorder

by Mark Reynolds,Washington University School of MedicineAn MRI scan shows a Chiari type-1 malformation, in which the cerebellum extends beyond the gap in the skull where it connects to the spin

Researchers define new subtypes of common brain disorder

by Mark Reynolds,Washington University School of MedicineAn MRI scan shows a Chiari type-1 malformation, in which the cerebellum extends beyond the gap in the skull where it connects to the spin
Scientists analyze virus protein structure to advance RSV vaccines

Scientists analyze virus protein structure to advance RSV vaccines

byThe Scripps Research InstituteComparative in vitro characterization of previously reported RSV-F designs. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-54287-xIn most

Scientists analyze virus protein structure to advance RSV vaccines

byThe Scripps Research InstituteComparative in vitro characterization of previously reported RSV-F designs. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-54287-xIn most
Flies fed restricted diet in early adulthood found to live longer

Flies fed restricted diet in early adulthood found to live longer

byRIKENA model of lifespan extension by early Met restriction. Methionine restriction in young flies can induce MsrA and decrease MetSO level, leading to lifespan extension. This nutritional res

Flies fed restricted diet in early adulthood found to live longer

byRIKENA model of lifespan extension by early Met restriction. Methionine restriction in young flies can induce MsrA and decrease MetSO level, leading to lifespan extension. This nutritional res
Anti-obesity medications may affect survival in people with knee or hip osteoarthritis

Anti-obesity medications may affect survival in people with knee or hip osteoarthritis

byWileyCredit: Pixabay/CC0 Public DomainNew researchpublishedinArthritis & Rheumatologysuggests that for people overweight or with obesity who also have knee or hip o

Anti-obesity medications may affect survival in people with knee or hip osteoarthritis

byWileyCredit: Pixabay/CC0 Public DomainNew researchpublishedinArthritis & Rheumatologysuggests that for people overweight or with obesity who also have knee or hip o
Imetelstat leads to durable red blood cell transfusion independence

Imetelstat leads to durable red blood cell transfusion independence

by Elana GotkineFor heavily transfused patients with lower-risk myelodysplastic syndromes (LR-MDS) who are not responding to or are ineligible for erythropoiesis-stimulating agents (ESAs), the competi

Imetelstat leads to durable red blood cell transfusion independence

by Elana GotkineFor heavily transfused patients with lower-risk myelodysplastic syndromes (LR-MDS) who are not responding to or are ineligible for erythropoiesis-stimulating agents (ESAs), the competi
Targeting the mRNA of 'undruggable' proteins in the fight against Parkinson's disease

Targeting the mRNA of 'undruggable' proteins in the fight against Parkinson's disease

JANUARY 8, 2024REPORTby Justin Jackson , Medical XpressCredit: Pixabay/CC0 Public DomainResearchers at the Scripps Research Institute, Florida, have developed a new method to counteract α-synucl

Targeting the mRNA of 'undruggable' proteins in the fight against Parkinson's disease

JANUARY 8, 2024REPORTby Justin Jackson , Medical XpressCredit: Pixabay/CC0 Public DomainResearchers at the Scripps Research Institute, Florida, have developed a new method to counteract α-synucl