FoxO6-mediated ApoC3 upregulation promotes hepatic steatosis and hyperlipidemia in HFD aged rats: Study

by Impact Journals LLCAging-related serum changes in insulin resistance and lipogenesis. (A) Glucose levels, (B) insulin levels, and (C) HOMA-IR scores were determined. (D) FFA (free fatty acid), (E)

Updated on: March 28,2024

FoxO6-mediated ApoC3 upregulation promotes hepatic steatosis and hyperlipidemia in HFD aged rats: Study

by Impact Journals LLCAging-related serum changes in insulin resistance and lipogenesis. (A) Glucose levels, (B) insulin levels, and (C) HOMA-IR scores were determined. (D) FFA (free fatty acid), (E)

Updated on:March 28,2024

Ozempic mania's billions in bills are coming for US taxpayers

by Simone Foxman, Laura Nahmias, Bloomberg NewsCredit: Markus Winkler from PexelsState and local governments across the US are grappling with a growing problem: Expensive drugs to treat diabetes and o

Updated on: January 26,2024

Ozempic mania's billions in bills are coming for US taxpayers

by Simone Foxman, Laura Nahmias, Bloomberg NewsCredit: Markus Winkler from PexelsState and local governments across the US are grappling with a growing problem: Expensive drugs to treat diabetes and o

Updated on:January 26,2024

Poison center calls related to injected weight-loss drugs up 1,500%

by Nancy Clanton, The Atlanta Journal-ConstitutionCredit: Pixabay/CC0 Public DomainAmerica's Poison Centers reported nearly 3,000 calls this year involving the weight loss drug semaglutide—a 15-fo

Updated on: January 26,2024

Poison center calls related to injected weight-loss drugs up 1,500%

by Nancy Clanton, The Atlanta Journal-ConstitutionCredit: Pixabay/CC0 Public DomainAmerica's Poison Centers reported nearly 3,000 calls this year involving the weight loss drug semaglutide—a 15-fo

Updated on:January 26,2024

New data shows prevalence of Premenstrual Dysphoric Disorder (PMDD)

New data shows prevalence of Premenstrual Dysphoric Disorder (PMDD)HEALTHMEDICAL SCIENCESMENTAL HEALTHRESEARCH29 January 2024Around 1.6% of women and girls have symptomatic Premenstrual Dysphoric Diso

Updated on: March 11,2024

New data shows prevalence of Premenstrual Dysphoric Disorder (PMDD)

New data shows prevalence of Premenstrual Dysphoric Disorder (PMDD)HEALTHMEDICAL SCIENCESMENTAL HEALTHRESEARCH29 January 2024Around 1.6% of women and girls have symptomatic Premenstrual Dysphoric Diso

Updated on:March 11,2024

Researchers present playbook of best practices for cancer team science in the modern era

by Break Through CancerThe Hallmarks of Cancer Collaboration. Based on Hanahan and Weinberg's seminal "Hallmarks of Cancer," this illustration proposes six Hallmarks of Cancer Collaborat

Updated on: April 06,2024

Researchers present playbook of best practices for cancer team science in the modern era

by Break Through CancerThe Hallmarks of Cancer Collaboration. Based on Hanahan and Weinberg's seminal "Hallmarks of Cancer," this illustration proposes six Hallmarks of Cancer Collaborat

Updated on:April 06,2024

Prolonged use of certain hormone drugs linked to increased brain tumor risk

by British Medical JournalMeningiomas are graded by microscopic appearance, rate of growth and tendency to invade other tissues. Credit: National Cancer InstituteProlonged use of certain progesto

Updated on: March 30,2024

Prolonged use of certain hormone drugs linked to increased brain tumor risk

by British Medical JournalMeningiomas are graded by microscopic appearance, rate of growth and tendency to invade other tissues. Credit: National Cancer InstituteProlonged use of certain progesto

Updated on:March 30,2024

Many antibiotic courses for common infections not in line with guidelines

by British Medical JournalCredit: CC0 Public DomainMany antibiotic courses prescribed for common infections treated in English primary care (general practices and community services) exceed the r

Updated on: March 06,2024

Many antibiotic courses for common infections not in line with guidelines

by British Medical JournalCredit: CC0 Public DomainMany antibiotic courses prescribed for common infections treated in English primary care (general practices and community services) exceed the r

Updated on:March 06,2024

Researchers help design easy-to-open, child-resistant medicine bottle

by Abby Robinson,Georgia Institute of TechnologyEquipment used by Georgia Tech Research Institute (GTRI) product design researchers measures the forces required to open prescription medicine con

Updated on: March 24,2024

Researchers help design easy-to-open, child-resistant medicine bottle

by Abby Robinson,Georgia Institute of TechnologyEquipment used by Georgia Tech Research Institute (GTRI) product design researchers measures the forces required to open prescription medicine con

Updated on:March 24,2024

Drug development advances in beneficial loss-of-function mutation targets validated by human genetics

by Sichuan International Medical Exchange and Promotion AssociationTargets primarily include PCSK9, ANGPTL3, HSD17B13, KHK, ASGR1, GPR75, CIDEB, and INHBE. Drug types primarily include small molecules

Updated on: March 28,2024

Drug development advances in beneficial loss-of-function mutation targets validated by human genetics

by Sichuan International Medical Exchange and Promotion AssociationTargets primarily include PCSK9, ANGPTL3, HSD17B13, KHK, ASGR1, GPR75, CIDEB, and INHBE. Drug types primarily include small molecules

Updated on:March 28,2024

Dicer enzyme cuts down on fats

by Ludwig Maximilian University of MunichDicer knockout in macrophages (right) accelerates atherosclerosis. Credit: Yuanyuan Wei, LMUThe enzyme Dicer cleaves long precursors into short RNA molecu

Updated on: April 12,2024

Dicer enzyme cuts down on fats

by Ludwig Maximilian University of MunichDicer knockout in macrophages (right) accelerates atherosclerosis. Credit: Yuanyuan Wei, LMUThe enzyme Dicer cleaves long precursors into short RNA molecu

Updated on:April 12,2024

The double-edge sword of CRISPR application for in vivo studies

by Impact Journals LLCWorkflow illustration. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.28459A new editorial paper titled "The double-edge sword of CRISPR application for in vi

Updated on: January 02,2024

The double-edge sword of CRISPR application for in vivo studies

by Impact Journals LLCWorkflow illustration. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.28459A new editorial paper titled "The double-edge sword of CRISPR application for in vi

Updated on:January 02,2024

Five-day antibiotic course noninferior for pediatric febrile UTI

by Elana GotkineFor young children with febrile urinary tract infection (fUTI), a five-day amoxicillin-clavulanate course is noninferior to a 10-day course for recurrence of UTI within 30 days after c

Updated on: January 26,2024

Five-day antibiotic course noninferior for pediatric febrile UTI

by Elana GotkineFor young children with febrile urinary tract infection (fUTI), a five-day amoxicillin-clavulanate course is noninferior to a 10-day course for recurrence of UTI within 30 days after c

Updated on:January 26,2024