New hope for patients with hereditary metabolic disease

by Fabio Bergamin,ETH ZurichIn methylmalonic aciduria, a specific metabolite accumulates in the body. This often leads to patients requiring intensive medical care. Credit: University Children&#

Updated on: February 19,2024

New hope for patients with hereditary metabolic disease

by Fabio Bergamin,ETH ZurichIn methylmalonic aciduria, a specific metabolite accumulates in the body. This often leads to patients requiring intensive medical care. Credit: University Children&#

Updated on:February 19,2024

Chronic lactate exposure leads to cellular disruptions implicated in cancer and possibly T2 diabetes

by CU Anschutz Medical CampusCredit: CC0 Public DomainAcute amounts of lactate like those generated during exercise are probably required for healthy cells, but chronic exposure causes cellular d

Updated on: February 05,2024

Chronic lactate exposure leads to cellular disruptions implicated in cancer and possibly T2 diabetes

by CU Anschutz Medical CampusCredit: CC0 Public DomainAcute amounts of lactate like those generated during exercise are probably required for healthy cells, but chronic exposure causes cellular d

Updated on:February 05,2024

The neonatal ketone body is important for primordial follicle pool formation and regulates ovarian aging in mice

by Higher Education PressThe working model for the function of ketone bodies in formation of primordial follicle pool. Credit: Xin-Ying Wang et alPremature ovarian aging (POA) refers to an early decli

Updated on: February 21,2024

The neonatal ketone body is important for primordial follicle pool formation and regulates ovarian aging in mice

by Higher Education PressThe working model for the function of ketone bodies in formation of primordial follicle pool. Credit: Xin-Ying Wang et alPremature ovarian aging (POA) refers to an early decli

Updated on:February 21,2024

Scientists create first humanized mouse model for rare genetic disease

by European Society of EndocrinologyCredit: CC0 Public DomainMice with a defective human gene responsible for a rare genetic disease called congenital adrenal hyperplasia, have been developed for the

Updated on: February 03,2024

Scientists create first humanized mouse model for rare genetic disease

by European Society of EndocrinologyCredit: CC0 Public DomainMice with a defective human gene responsible for a rare genetic disease called congenital adrenal hyperplasia, have been developed for the

Updated on:February 03,2024

Letting go of extra weight to control sleeping sickness

byInstituto de Medicina MolecularProtective effect of adipocyte lipolysis in murine T. brucei infection. Graphical representation of the effects of ATGL-dependent lipolysis. ATGL activity promot

Updated on: January 17,2024

Letting go of extra weight to control sleeping sickness

byInstituto de Medicina MolecularProtective effect of adipocyte lipolysis in murine T. brucei infection. Graphical representation of the effects of ATGL-dependent lipolysis. ATGL activity promot

Updated on:January 17,2024

New machine-learning method predicts body clock timing to improve sleep and health decisions

by University of SurreyCredit: Pixabay/CC0 Public DomainA new machine-learning method could help us gauge the time of our internal body clock, helping us all make better health decisions, includi

Updated on: February 21,2024

New machine-learning method predicts body clock timing to improve sleep and health decisions

by University of SurreyCredit: Pixabay/CC0 Public DomainA new machine-learning method could help us gauge the time of our internal body clock, helping us all make better health decisions, includi

Updated on:February 21,2024

Increasing skeletal muscle mitochondrial efficiency after weight loss as a novel mechanism for lower energy expenditure

by Higher Education PressTLCL deficiency reduces OXPHOS efficiency. Credit: Patrick J Ferrara, Marisa J Lang, Jordan M Johnson, Shinya Watanabe, Kelsey L McLaughlin, J Alan Maschek, Anthony R P Verker

Updated on: February 05,2024

Increasing skeletal muscle mitochondrial efficiency after weight loss as a novel mechanism for lower energy expenditure

by Higher Education PressTLCL deficiency reduces OXPHOS efficiency. Credit: Patrick J Ferrara, Marisa J Lang, Jordan M Johnson, Shinya Watanabe, Kelsey L McLaughlin, J Alan Maschek, Anthony R P Verker

Updated on:February 05,2024

High aerobic fitness does not protect children from metabolic syndrome, study finds

by University of JyväskyläDifferences in V̇O2peakamong children with different numbers of cardiometabolic risk factors. The metabolic syndrome was defined using the modified National Choles

Updated on: February 21,2024

High aerobic fitness does not protect children from metabolic syndrome, study finds

by University of JyväskyläDifferences in V̇O2peakamong children with different numbers of cardiometabolic risk factors. The metabolic syndrome was defined using the modified National Choles

Updated on:February 21,2024

Non-COVID-19 deaths among people with diabetes jumped during pandemic, global study reveals

by University of Massachusetts AmherstCredit: Pixabay/CC0 Public DomainNon-COVID-19-related deaths among people with diabetes increased during the pandemic, as did the diabetes complication of si

Updated on: March 05,2024

Non-COVID-19 deaths among people with diabetes jumped during pandemic, global study reveals

by University of Massachusetts AmherstCredit: Pixabay/CC0 Public DomainNon-COVID-19-related deaths among people with diabetes increased during the pandemic, as did the diabetes complication of si

Updated on:March 05,2024

Sparse system identification of leptin dynamics in women with obesity

by NYU Tandon School of EngineeringResearchers studyingthe relationship between leptin and obesity found statistically significant relationships between leptin secretion characteristics and

Updated on: January 31,2024

Sparse system identification of leptin dynamics in women with obesity

by NYU Tandon School of EngineeringResearchers studyingthe relationship between leptin and obesity found statistically significant relationships between leptin secretion characteristics and

Updated on:January 31,2024

Fat buildup in liver linked to heightened heart failure risk over next decade

by British Medical JournalCredit: Pixabay/CC0 Public DomainThe buildup of fat in the liver, known as non-alcoholic fatty liver disease, or NAFLD for short, is linked to a heightened risk of heart

Updated on: February 03,2024

Fat buildup in liver linked to heightened heart failure risk over next decade

by British Medical JournalCredit: Pixabay/CC0 Public DomainThe buildup of fat in the liver, known as non-alcoholic fatty liver disease, or NAFLD for short, is linked to a heightened risk of heart

Updated on:February 03,2024

Suppressed ovarian follicle development in women with obesity may explain reduced fertility

by The Endocrine SocietyCredit: CC0 Public DomainWomen with obesity, even those with regular menstrual cycles, have suppressed ovarian follicle development and reduced production of reproductive

Updated on: January 31,2024

Suppressed ovarian follicle development in women with obesity may explain reduced fertility

by The Endocrine SocietyCredit: CC0 Public DomainWomen with obesity, even those with regular menstrual cycles, have suppressed ovarian follicle development and reduced production of reproductive

Updated on:January 31,2024