SMNDC1 loss induces alpha cells to produce insulin

by Austrian Academy of SciencesImmunofluorescence images of alpha cells highlighting induction of insulin protein upon loss of SMNDC1. Credit: Tamara Casteels,CellReport 2022.Beta cells in

Updated on: January 28,2024

SMNDC1 loss induces alpha cells to produce insulin

by Austrian Academy of SciencesImmunofluorescence images of alpha cells highlighting induction of insulin protein upon loss of SMNDC1. Credit: Tamara Casteels,CellReport 2022.Beta cells in

Updated on:January 28,2024

Discovery could help reduce adverse side effects of popular next-generation obesity medications

byMonell Chemical Senses CenterActivating GLP1 receptor-expressing neurons in the nucleus tractus solitarius (magenta) increase sateity without causing nausea or aversion. Credit: Alisha Acosta,

Updated on: July 11,2024

Discovery could help reduce adverse side effects of popular next-generation obesity medications

byMonell Chemical Senses CenterActivating GLP1 receptor-expressing neurons in the nucleus tractus solitarius (magenta) increase sateity without causing nausea or aversion. Credit: Alisha Acosta,

Updated on:July 11,2024

Metabolism may be key to future treatment of kidney diseases

by Aarhus UniversityCredit: Pixabay/CC0 Public DomainCan you eat your way out of a kidney disease? Perhaps you can—according to a new study from Aarhus University.In the study, Associate Professo

Updated on: January 31,2024

Metabolism may be key to future treatment of kidney diseases

by Aarhus UniversityCredit: Pixabay/CC0 Public DomainCan you eat your way out of a kidney disease? Perhaps you can—according to a new study from Aarhus University.In the study, Associate Professo

Updated on:January 31,2024

Dominant form of heart failure caused by metabolic-immune interaction, review article suggests

by UT Southwestern Medical CenterCredit: Pixabay/CC0 Public DomainThe dominant form of heart failure worldwide appears to be caused by a strong, bidirectional interaction between the body's r

Updated on: February 19,2024

Dominant form of heart failure caused by metabolic-immune interaction, review article suggests

by UT Southwestern Medical CenterCredit: Pixabay/CC0 Public DomainThe dominant form of heart failure worldwide appears to be caused by a strong, bidirectional interaction between the body's r

Updated on:February 19,2024

Researchers have uncovered a regulator of body weight that could lead to new treatments for metabolic disorders

by Yale UniversityCredit: Pixabay/CC0 Public DomainYale scientists have discovered that a protein known as augmentor-alpha regulates body weight in mice, an insight that could lead to new treatme

Updated on: February 19,2024

Researchers have uncovered a regulator of body weight that could lead to new treatments for metabolic disorders

by Yale UniversityCredit: Pixabay/CC0 Public DomainYale scientists have discovered that a protein known as augmentor-alpha regulates body weight in mice, an insight that could lead to new treatme

Updated on:February 19,2024

Sparse system identification of leptin dynamics in women with obesity

by NYU Tandon School of EngineeringResearchers studyingthe relationship between leptin and obesity found statistically significant relationships between leptin secretion characteristics and

Updated on: January 31,2024

Sparse system identification of leptin dynamics in women with obesity

by NYU Tandon School of EngineeringResearchers studyingthe relationship between leptin and obesity found statistically significant relationships between leptin secretion characteristics and

Updated on:January 31,2024

While waiting for food: The surprising fetal gut cells that make insulin

by Weizmann Institute of ScienceIn both the FIKL cells in the small intestine (top) and beta cells in the pancreas (bottom), the mRNA molecules for making insulin (magenta) are found closer to th

Updated on: January 31,2024

While waiting for food: The surprising fetal gut cells that make insulin

by Weizmann Institute of ScienceIn both the FIKL cells in the small intestine (top) and beta cells in the pancreas (bottom), the mRNA molecules for making insulin (magenta) are found closer to th

Updated on:January 31,2024

Scientific review suggests even normal-weight individuals are susceptible to severe fatty liver disease

by The Translational Genomics Research InstitutePotential contributors to NAFLD in lean individuals. Despite the same pathological findings in the liver, the factors that contribute to NAFLD and

Updated on: February 05,2024

Scientific review suggests even normal-weight individuals are susceptible to severe fatty liver disease

by The Translational Genomics Research InstitutePotential contributors to NAFLD in lean individuals. Despite the same pathological findings in the liver, the factors that contribute to NAFLD and

Updated on:February 05,2024

Chronic lactate exposure leads to cellular disruptions implicated in cancer and possibly T2 diabetes

by CU Anschutz Medical CampusCredit: CC0 Public DomainAcute amounts of lactate like those generated during exercise are probably required for healthy cells, but chronic exposure causes cellular d

Updated on: February 05,2024

Chronic lactate exposure leads to cellular disruptions implicated in cancer and possibly T2 diabetes

by CU Anschutz Medical CampusCredit: CC0 Public DomainAcute amounts of lactate like those generated during exercise are probably required for healthy cells, but chronic exposure causes cellular d

Updated on:February 05,2024

Menopause and the heart connection

by Deb Balzer3D Model of the heart by Dr. Matthew Bramlet. Credit: NIHWomen experience menopause at different ages—and different ways—which can, among other things, affect their heart health.The avera

Updated on: January 31,2024

Menopause and the heart connection

by Deb Balzer3D Model of the heart by Dr. Matthew Bramlet. Credit: NIHWomen experience menopause at different ages—and different ways—which can, among other things, affect their heart health.The avera

Updated on:January 31,2024

Novel biomarker for glucocorticoids could help tailor treatments

by eLifeBall-and-stick model of the cortisol (hydrocortisone) molecule. Credit: Public DomainResearchers have uncovered pathways involved in the body's response to glucocorticoid treatments a

Updated on: February 21,2024

Novel biomarker for glucocorticoids could help tailor treatments

by eLifeBall-and-stick model of the cortisol (hydrocortisone) molecule. Credit: Public DomainResearchers have uncovered pathways involved in the body's response to glucocorticoid treatments a

Updated on:February 21,2024

Inhibiting production of a key material biosynthesis to slow tumor growth

by Will Doss,Northwestern UniversitySAM inhibitor drastically reduced cancer growth in models of human cancer. Credit: Northwestern UniversityMany cancers hijack a metabolic mechanism known as t

Updated on: February 21,2024

Inhibiting production of a key material biosynthesis to slow tumor growth

by Will Doss,Northwestern UniversitySAM inhibitor drastically reduced cancer growth in models of human cancer. Credit: Northwestern UniversityMany cancers hijack a metabolic mechanism known as t

Updated on:February 21,2024