Scientists create first humanized mouse model for rare genetic disease

by European Society of EndocrinologyCredit: CC0 Public DomainMice with a defective human gene responsible for a rare genetic disease called congenital adrenal hyperplasia, have been developed for the

Updated on: February 03,2024 25

Scientists create first humanized mouse model for rare genetic disease

by European Society of EndocrinologyCredit: CC0 Public DomainMice with a defective human gene responsible for a rare genetic disease called congenital adrenal hyperplasia, have been developed for the

Updated on:February 03,2024 25

Important role of intestinal immune cells in iron deficiency identified for the first time

by Medical University of ViennaTSC2 deletion in myeloid cells impairs medullary erythropoiesis. (A) Schematic representation of the genetic background of cre/+ mice vs +/+ controls. TSC2 knockout

Updated on: February 21,2024 15

Important role of intestinal immune cells in iron deficiency identified for the first time

by Medical University of ViennaTSC2 deletion in myeloid cells impairs medullary erythropoiesis. (A) Schematic representation of the genetic background of cre/+ mice vs +/+ controls. TSC2 knockout

Updated on:February 21,2024 15

Hormone exposure in the womb potentially linked to migraine risk in later life

by FrontiersCredit: Pixabay/CC0 Public DomainHormone levels in the womb before birth have been potentially linked to the risk of developing migraine in adulthood, reveals a new study of genetic a

Updated on: February 19,2024 12

Hormone exposure in the womb potentially linked to migraine risk in later life

by FrontiersCredit: Pixabay/CC0 Public DomainHormone levels in the womb before birth have been potentially linked to the risk of developing migraine in adulthood, reveals a new study of genetic a

Updated on:February 19,2024 12

Intermittent fasting improves Alzheimer's pathology in mouse model

Intermittent fasting improves Alzheimer's pathology in mouse modelbyUniversity of California - San DiegoThis confocal microscopy image shows amyloid plaques (blue and red) in the brain of a

Updated on: January 24,2024 18

Intermittent fasting improves Alzheimer's pathology in mouse model

Intermittent fasting improves Alzheimer's pathology in mouse modelbyUniversity of California - San DiegoThis confocal microscopy image shows amyloid plaques (blue and red) in the brain of a

Updated on:January 24,2024 18

Worldwide audit finds testosterone replacement improves blood sugar control in men with type 2 diabetes

byDiabetologiaCredit: CC0 Public DomainReal-world data from an ongoing international audit of testosterone deficiency in men with type 2 diabetes, presented at theAnnual Meeting of The Eur

Updated on: January 17,2024 16

Worldwide audit finds testosterone replacement improves blood sugar control in men with type 2 diabetes

byDiabetologiaCredit: CC0 Public DomainReal-world data from an ongoing international audit of testosterone deficiency in men with type 2 diabetes, presented at theAnnual Meeting of The Eur

Updated on:January 17,2024 16

Could cholesterol explain why childhood obesity leads to early puberty?

by University of CopenhagenDietary cholesterol systemically promotes growth through insulin signaling(A) Larval growth on synthetic medium, reflected in pupal size, increases with increasing diet

Updated on: February 03,2024 10

Could cholesterol explain why childhood obesity leads to early puberty?

by University of CopenhagenDietary cholesterol systemically promotes growth through insulin signaling(A) Larval growth on synthetic medium, reflected in pupal size, increases with increasing diet

Updated on:February 03,2024 10

Bariatric surgery may cut risk of obesity-related cancers by more than half

by Digestive Disease WeekCredit: Pixabay/CC0 Public DomainJust 4% of patients with obesity who underwent bariatric surgery developed obesity-associated cancer in a 10-year follow up, compared to 8.9%

Updated on: June 12,2024 7

Bariatric surgery may cut risk of obesity-related cancers by more than half

by Digestive Disease WeekCredit: Pixabay/CC0 Public DomainJust 4% of patients with obesity who underwent bariatric surgery developed obesity-associated cancer in a 10-year follow up, compared to 8.9%

Updated on:June 12,2024 7

Molecule boosts fat burning

by University of BonnHuman brown adipocytes, lipid stained red (RedO oil stain). Credit: Laia Reverte Salisa / University of BonnNormally, fat cells store energy. In brown fat cells, however, ene

Updated on: February 03,2024 11

Molecule boosts fat burning

by University of BonnHuman brown adipocytes, lipid stained red (RedO oil stain). Credit: Laia Reverte Salisa / University of BonnNormally, fat cells store energy. In brown fat cells, however, ene

Updated on:February 03,2024 11

A new way to fight diseases? Stop viruses from stealing nutrients

by Leslie Tate,Tulane UniversityHost nutrient metabolism is altered in response to viruses. a, Viruses such as HCV and SARS-CoV-2 interact with entry/metabolic factors to increase fatty acid syn

Updated on: January 31,2024 16

A new way to fight diseases? Stop viruses from stealing nutrients

by Leslie Tate,Tulane UniversityHost nutrient metabolism is altered in response to viruses. a, Viruses such as HCV and SARS-CoV-2 interact with entry/metabolic factors to increase fatty acid syn

Updated on:January 31,2024 16

Longer siestas linked to higher risk of obesity, metabolic syndrome and high blood pressure

byBrigham and Women's Hospital(A) Mediated total effect of long siestas vs. no siesta on BMI. (B) Mediated total effect of long siestas vs. no siesta on glucose. (C) Mediated total effect of

Updated on: February 21,2024 8

Longer siestas linked to higher risk of obesity, metabolic syndrome and high blood pressure

byBrigham and Women's Hospital(A) Mediated total effect of long siestas vs. no siesta on BMI. (B) Mediated total effect of long siestas vs. no siesta on glucose. (C) Mediated total effect of

Updated on:February 21,2024 8

Scientists demonstrate a combination treatment can increase human insulin-producing cells in vivo

byThe Mount Sinai HospitalCredit: CC0 Public DomainIn preclinical studies, a team of researchers from Mount Sinai Health System in New York City and City of Hope in Los Angeles report new findin

Updated on: July 17,2024 0

Scientists demonstrate a combination treatment can increase human insulin-producing cells in vivo

byThe Mount Sinai HospitalCredit: CC0 Public DomainIn preclinical studies, a team of researchers from Mount Sinai Health System in New York City and City of Hope in Los Angeles report new findin

Updated on:July 17,2024 0

Metabolism meets signaling to fine-tune cell growth

by Maren Berghoff,Max Planck SocietyFunctional pharmacogenetic interactions between TOR-pathway genes, and Acc1 and Fas1 activity in yeast.a, Schematic diagram of de novo FA biosynthesis.

Updated on: January 24,2024 10

Metabolism meets signaling to fine-tune cell growth

by Maren Berghoff,Max Planck SocietyFunctional pharmacogenetic interactions between TOR-pathway genes, and Acc1 and Fas1 activity in yeast.a, Schematic diagram of de novo FA biosynthesis.

Updated on:January 24,2024 10