Chronic lactate exposure leads to cellular disruptions implicated in cancer and possibly T2 diabetes

by CU Anschutz Medical CampusCredit: CC0 Public DomainAcute amounts of lactate like those generated during exercise are probably required for healthy cells, but chronic exposure causes cellular d

Updated on: February 05,2024

Chronic lactate exposure leads to cellular disruptions implicated in cancer and possibly T2 diabetes

by CU Anschutz Medical CampusCredit: CC0 Public DomainAcute amounts of lactate like those generated during exercise are probably required for healthy cells, but chronic exposure causes cellular d

Updated on:February 05,2024

Reducing stress on T cells makes them better cancer fighters

bySalk InstituteExhausted killer T cells with higher expression of the noradrenaline receptor ADRB1 (cyan) surround sympathetic nerves (yellow) in a virally infected spleen. Killer T cells witho

Updated on: January 20,2024

Reducing stress on T cells makes them better cancer fighters

bySalk InstituteExhausted killer T cells with higher expression of the noradrenaline receptor ADRB1 (cyan) surround sympathetic nerves (yellow) in a virally infected spleen. Killer T cells witho

Updated on:January 20,2024

The neonatal ketone body is important for primordial follicle pool formation and regulates ovarian aging in mice

by Higher Education PressThe working model for the function of ketone bodies in formation of primordial follicle pool. Credit: Xin-Ying Wang et alPremature ovarian aging (POA) refers to an early decli

Updated on: February 21,2024

The neonatal ketone body is important for primordial follicle pool formation and regulates ovarian aging in mice

by Higher Education PressThe working model for the function of ketone bodies in formation of primordial follicle pool. Credit: Xin-Ying Wang et alPremature ovarian aging (POA) refers to an early decli

Updated on:February 21,2024

Clinical trial identifies potential new treatment for liver disease

Clinical trial identifies potential new treatment for liver diseasebyUniversity of California - San DiegoCredit: Pixabay/CC0 Public DomainResearchers at the University of California San Diego Sc

Updated on: January 24,2024

Clinical trial identifies potential new treatment for liver disease

Clinical trial identifies potential new treatment for liver diseasebyUniversity of California - San DiegoCredit: Pixabay/CC0 Public DomainResearchers at the University of California San Diego Sc

Updated on:January 24,2024

GDF15 hormone found to make insulin work better

byUniversity of CopenhagenGraphical abstract. Credit:Cell Metabolism(2023). DOI: 10.1016/j.cmet.2023.06.016More than 500 million people worldwide suffer from diabetes. Roughly 2.6 bi

Updated on: January 17,2024

GDF15 hormone found to make insulin work better

byUniversity of CopenhagenGraphical abstract. Credit:Cell Metabolism(2023). DOI: 10.1016/j.cmet.2023.06.016More than 500 million people worldwide suffer from diabetes. Roughly 2.6 bi

Updated on:January 17,2024

Is diabetes remission really as hard to achieve as a new study suggests?

by Duane Mellor, Craig Russell and Srikanth Bellary,The ConversationCredit: Pixabay/CC0 Public DomainIn 2017, alandmark studywas published inThe Lancetshowing that type 2

Updated on: March 05,2024

Is diabetes remission really as hard to achieve as a new study suggests?

by Duane Mellor, Craig Russell and Srikanth Bellary,The ConversationCredit: Pixabay/CC0 Public DomainIn 2017, alandmark studywas published inThe Lancetshowing that type 2

Updated on:March 05,2024

Inhibiting production of a key material biosynthesis to slow tumor growth

by Will Doss,Northwestern UniversitySAM inhibitor drastically reduced cancer growth in models of human cancer. Credit: Northwestern UniversityMany cancers hijack a metabolic mechanism known as t

Updated on: February 21,2024

Inhibiting production of a key material biosynthesis to slow tumor growth

by Will Doss,Northwestern UniversitySAM inhibitor drastically reduced cancer growth in models of human cancer. Credit: Northwestern UniversityMany cancers hijack a metabolic mechanism known as t

Updated on:February 21,2024

Dominant form of heart failure caused by metabolic-immune interaction, review article suggests

by UT Southwestern Medical CenterCredit: Pixabay/CC0 Public DomainThe dominant form of heart failure worldwide appears to be caused by a strong, bidirectional interaction between the body's r

Updated on: February 19,2024

Dominant form of heart failure caused by metabolic-immune interaction, review article suggests

by UT Southwestern Medical CenterCredit: Pixabay/CC0 Public DomainThe dominant form of heart failure worldwide appears to be caused by a strong, bidirectional interaction between the body's r

Updated on:February 19,2024

White adipose tissue is found to be the most vulnerable to metabolic changes caused by obesity

by University of BarcelonaThis is an image of a weight scale. Credit: CDC/Debora CartagenaWhen the body is subjected to a high-calorie diet, the physiological response is not homogeneous and some

Updated on: February 19,2024

White adipose tissue is found to be the most vulnerable to metabolic changes caused by obesity

by University of BarcelonaThis is an image of a weight scale. Credit: CDC/Debora CartagenaWhen the body is subjected to a high-calorie diet, the physiological response is not homogeneous and some

Updated on:February 19,2024

Mom's dietary fat rewires male and female brains differently

by Duke UniversityA microglia (in magenta) from a male mouse born to a mom on a high-fat diet, which sequesters more brain serotonin (in green) than males with mom’s eating a typical lab diet. Th

Updated on: February 21,2024

Mom's dietary fat rewires male and female brains differently

by Duke UniversityA microglia (in magenta) from a male mouse born to a mom on a high-fat diet, which sequesters more brain serotonin (in green) than males with mom’s eating a typical lab diet. Th

Updated on:February 21,2024

Timing calorie intake synchronizes circadian rhythms across multiple systems in mice

by Salk InstituteGraphical abstract. Credit:Cell Metabolism(2023). DOI: 10.1016/j.cmet.2022.12.006Numerous studies have shown health benefits of time-restricted eating including incre

Updated on: January 31,2024

Timing calorie intake synchronizes circadian rhythms across multiple systems in mice

by Salk InstituteGraphical abstract. Credit:Cell Metabolism(2023). DOI: 10.1016/j.cmet.2022.12.006Numerous studies have shown health benefits of time-restricted eating including incre

Updated on:January 31,2024

Doctors could soon use facial temperature for early diagnosis of metabolic diseases

byCell PressAverage facial temperatures of three aging-status groups among women 50–60 years old. Credit: Zhengqing Yu and Jing-Dong J HanA colder nose and warmer cheeks may be a telltale sign o

Updated on: July 05,2024

Doctors could soon use facial temperature for early diagnosis of metabolic diseases

byCell PressAverage facial temperatures of three aging-status groups among women 50–60 years old. Credit: Zhengqing Yu and Jing-Dong J HanA colder nose and warmer cheeks may be a telltale sign o

Updated on:July 05,2024