Chronic lactate exposure leads to cellular disruptions implicated in cancer and possibly T2 diabetes

by CU Anschutz Medical CampusCredit: CC0 Public DomainAcute amounts of lactate like those generated during exercise are probably required for healthy cells, but chronic exposure causes cellular d

Updated on: February 05,2024

Chronic lactate exposure leads to cellular disruptions implicated in cancer and possibly T2 diabetes

by CU Anschutz Medical CampusCredit: CC0 Public DomainAcute amounts of lactate like those generated during exercise are probably required for healthy cells, but chronic exposure causes cellular d

Updated on:February 05,2024

The neonatal ketone body is important for primordial follicle pool formation and regulates ovarian aging in mice

by Higher Education PressThe working model for the function of ketone bodies in formation of primordial follicle pool. Credit: Xin-Ying Wang et alPremature ovarian aging (POA) refers to an early decli

Updated on: February 21,2024

The neonatal ketone body is important for primordial follicle pool formation and regulates ovarian aging in mice

by Higher Education PressThe working model for the function of ketone bodies in formation of primordial follicle pool. Credit: Xin-Ying Wang et alPremature ovarian aging (POA) refers to an early decli

Updated on:February 21,2024

GDF15 hormone found to make insulin work better

byUniversity of CopenhagenGraphical abstract. Credit:Cell Metabolism(2023). DOI: 10.1016/j.cmet.2023.06.016More than 500 million people worldwide suffer from diabetes. Roughly 2.6 bi

Updated on: January 17,2024

GDF15 hormone found to make insulin work better

byUniversity of CopenhagenGraphical abstract. Credit:Cell Metabolism(2023). DOI: 10.1016/j.cmet.2023.06.016More than 500 million people worldwide suffer from diabetes. Roughly 2.6 bi

Updated on:January 17,2024

Reducing stress on T cells makes them better cancer fighters

bySalk InstituteExhausted killer T cells with higher expression of the noradrenaline receptor ADRB1 (cyan) surround sympathetic nerves (yellow) in a virally infected spleen. Killer T cells witho

Updated on: January 20,2024

Reducing stress on T cells makes them better cancer fighters

bySalk InstituteExhausted killer T cells with higher expression of the noradrenaline receptor ADRB1 (cyan) surround sympathetic nerves (yellow) in a virally infected spleen. Killer T cells witho

Updated on:January 20,2024

Increasing skeletal muscle mitochondrial efficiency after weight loss as a novel mechanism for lower energy expenditure

by Higher Education PressTLCL deficiency reduces OXPHOS efficiency. Credit: Patrick J Ferrara, Marisa J Lang, Jordan M Johnson, Shinya Watanabe, Kelsey L McLaughlin, J Alan Maschek, Anthony R P Verker

Updated on: February 05,2024

Increasing skeletal muscle mitochondrial efficiency after weight loss as a novel mechanism for lower energy expenditure

by Higher Education PressTLCL deficiency reduces OXPHOS efficiency. Credit: Patrick J Ferrara, Marisa J Lang, Jordan M Johnson, Shinya Watanabe, Kelsey L McLaughlin, J Alan Maschek, Anthony R P Verker

Updated on:February 05,2024

White adipose tissue is found to be the most vulnerable to metabolic changes caused by obesity

by University of BarcelonaThis is an image of a weight scale. Credit: CDC/Debora CartagenaWhen the body is subjected to a high-calorie diet, the physiological response is not homogeneous and some

Updated on: February 19,2024

White adipose tissue is found to be the most vulnerable to metabolic changes caused by obesity

by University of BarcelonaThis is an image of a weight scale. Credit: CDC/Debora CartagenaWhen the body is subjected to a high-calorie diet, the physiological response is not homogeneous and some

Updated on:February 19,2024

Is diabetes remission really as hard to achieve as a new study suggests?

by Duane Mellor, Craig Russell and Srikanth Bellary,The ConversationCredit: Pixabay/CC0 Public DomainIn 2017, alandmark studywas published inThe Lancetshowing that type 2

Updated on: March 05,2024

Is diabetes remission really as hard to achieve as a new study suggests?

by Duane Mellor, Craig Russell and Srikanth Bellary,The ConversationCredit: Pixabay/CC0 Public DomainIn 2017, alandmark studywas published inThe Lancetshowing that type 2

Updated on:March 05,2024

Mom's dietary fat rewires male and female brains differently

by Duke UniversityA microglia (in magenta) from a male mouse born to a mom on a high-fat diet, which sequesters more brain serotonin (in green) than males with mom’s eating a typical lab diet. Th

Updated on: February 21,2024

Mom's dietary fat rewires male and female brains differently

by Duke UniversityA microglia (in magenta) from a male mouse born to a mom on a high-fat diet, which sequesters more brain serotonin (in green) than males with mom’s eating a typical lab diet. Th

Updated on:February 21,2024

Clinical trial identifies potential new treatment for liver disease

Clinical trial identifies potential new treatment for liver diseasebyUniversity of California - San DiegoCredit: Pixabay/CC0 Public DomainResearchers at the University of California San Diego Sc

Updated on: January 24,2024

Clinical trial identifies potential new treatment for liver disease

Clinical trial identifies potential new treatment for liver diseasebyUniversity of California - San DiegoCredit: Pixabay/CC0 Public DomainResearchers at the University of California San Diego Sc

Updated on:January 24,2024

Implanted cells triggered by electricity used to drive in vivo gene expression

by Justin Jackson , Medical XpressDesign of the direct-current-activated transgene expression switch in mammalian cells.a, Schematic illustration of the stimulation setup for monolayer cultures.

Updated on: January 24,2024

Implanted cells triggered by electricity used to drive in vivo gene expression

by Justin Jackson , Medical XpressDesign of the direct-current-activated transgene expression switch in mammalian cells.a, Schematic illustration of the stimulation setup for monolayer cultures.

Updated on:January 24,2024

Study offers explanation for why only some develop posttraumatic stress disorder

by Nik Papageorgiou,Ecole Polytechnique Federale de LausanneA map of voxelwise differences in gray matter volume between low-CR and Ctr rats calculated from exvivo magnetic resonance image

Updated on: January 09,2024

Study offers explanation for why only some develop posttraumatic stress disorder

by Nik Papageorgiou,Ecole Polytechnique Federale de LausanneA map of voxelwise differences in gray matter volume between low-CR and Ctr rats calculated from exvivo magnetic resonance image

Updated on:January 09,2024

Exposure to dioxins can worsen thyroid function

byThe Endocrine SocietyCredit: Pixabay/CC0 Public DomainExposure to dioxins can negatively impact thyroid function, according to a study presented Thursday at ENDO 2023, the Endocrine Society&#3

Updated on: January 22,2024

Exposure to dioxins can worsen thyroid function

byThe Endocrine SocietyCredit: Pixabay/CC0 Public DomainExposure to dioxins can negatively impact thyroid function, according to a study presented Thursday at ENDO 2023, the Endocrine Society&#3

Updated on:January 22,2024