Reducing stress on T cells makes them better cancer fighters

bySalk InstituteExhausted killer T cells with higher expression of the noradrenaline receptor ADRB1 (cyan) surround sympathetic nerves (yellow) in a virally infected spleen. Killer T cells witho

Updated on: January 20,2024

Reducing stress on T cells makes them better cancer fighters

bySalk InstituteExhausted killer T cells with higher expression of the noradrenaline receptor ADRB1 (cyan) surround sympathetic nerves (yellow) in a virally infected spleen. Killer T cells witho

Updated on:January 20,2024

Is diabetes remission really as hard to achieve as a new study suggests?

by Duane Mellor, Craig Russell and Srikanth Bellary,The ConversationCredit: Pixabay/CC0 Public DomainIn 2017, alandmark studywas published inThe Lancetshowing that type 2

Updated on: March 05,2024

Is diabetes remission really as hard to achieve as a new study suggests?

by Duane Mellor, Craig Russell and Srikanth Bellary,The ConversationCredit: Pixabay/CC0 Public DomainIn 2017, alandmark studywas published inThe Lancetshowing that type 2

Updated on:March 05,2024

New study questions the role of supercomplexes in metabolism and disease

byKarolinska InstitutetSupercomplexes. Credit: Nils-Göran Larsson's labA new study published inCell Metabolismby the research group of Professor Nils-Göran Larsson, at the Depart

Updated on: January 17,2024

New study questions the role of supercomplexes in metabolism and disease

byKarolinska InstitutetSupercomplexes. Credit: Nils-Göran Larsson's labA new study published inCell Metabolismby the research group of Professor Nils-Göran Larsson, at the Depart

Updated on:January 17,2024

White adipose tissue is found to be the most vulnerable to metabolic changes caused by obesity

by University of BarcelonaThis is an image of a weight scale. Credit: CDC/Debora CartagenaWhen the body is subjected to a high-calorie diet, the physiological response is not homogeneous and some

Updated on: February 19,2024

White adipose tissue is found to be the most vulnerable to metabolic changes caused by obesity

by University of BarcelonaThis is an image of a weight scale. Credit: CDC/Debora CartagenaWhen the body is subjected to a high-calorie diet, the physiological response is not homogeneous and some

Updated on:February 19,2024

Isolation severely impacts diabetes management

by Anglia Ruskin UniversityCredit: Unsplash/CC0 Public DomainNew research has found that patients' self-management of their diabetes has suffered during the COVID-19 pandemic, particularly du

Updated on: January 31,2024

Isolation severely impacts diabetes management

by Anglia Ruskin UniversityCredit: Unsplash/CC0 Public DomainNew research has found that patients' self-management of their diabetes has suffered during the COVID-19 pandemic, particularly du

Updated on:January 31,2024

Inhibiting production of a key material biosynthesis to slow tumor growth

by Will Doss,Northwestern UniversitySAM inhibitor drastically reduced cancer growth in models of human cancer. Credit: Northwestern UniversityMany cancers hijack a metabolic mechanism known as t

Updated on: February 21,2024

Inhibiting production of a key material biosynthesis to slow tumor growth

by Will Doss,Northwestern UniversitySAM inhibitor drastically reduced cancer growth in models of human cancer. Credit: Northwestern UniversityMany cancers hijack a metabolic mechanism known as t

Updated on:February 21,2024

Dominant form of heart failure caused by metabolic-immune interaction, review article suggests

by UT Southwestern Medical CenterCredit: Pixabay/CC0 Public DomainThe dominant form of heart failure worldwide appears to be caused by a strong, bidirectional interaction between the body's r

Updated on: February 19,2024

Dominant form of heart failure caused by metabolic-immune interaction, review article suggests

by UT Southwestern Medical CenterCredit: Pixabay/CC0 Public DomainThe dominant form of heart failure worldwide appears to be caused by a strong, bidirectional interaction between the body's r

Updated on:February 19,2024

SMNDC1 loss induces alpha cells to produce insulin

by Austrian Academy of SciencesImmunofluorescence images of alpha cells highlighting induction of insulin protein upon loss of SMNDC1. Credit: Tamara Casteels,CellReport 2022.Beta cells in

Updated on: January 28,2024

SMNDC1 loss induces alpha cells to produce insulin

by Austrian Academy of SciencesImmunofluorescence images of alpha cells highlighting induction of insulin protein upon loss of SMNDC1. Credit: Tamara Casteels,CellReport 2022.Beta cells in

Updated on:January 28,2024

Mom's dietary fat rewires male and female brains differently

by Duke UniversityA microglia (in magenta) from a male mouse born to a mom on a high-fat diet, which sequesters more brain serotonin (in green) than males with mom’s eating a typical lab diet. Th

Updated on: February 21,2024

Mom's dietary fat rewires male and female brains differently

by Duke UniversityA microglia (in magenta) from a male mouse born to a mom on a high-fat diet, which sequesters more brain serotonin (in green) than males with mom’s eating a typical lab diet. Th

Updated on:February 21,2024

GDF15 hormone found to make insulin work better

byUniversity of CopenhagenGraphical abstract. Credit:Cell Metabolism(2023). DOI: 10.1016/j.cmet.2023.06.016More than 500 million people worldwide suffer from diabetes. Roughly 2.6 bi

Updated on: January 17,2024

GDF15 hormone found to make insulin work better

byUniversity of CopenhagenGraphical abstract. Credit:Cell Metabolism(2023). DOI: 10.1016/j.cmet.2023.06.016More than 500 million people worldwide suffer from diabetes. Roughly 2.6 bi

Updated on:January 17,2024

Increasing skeletal muscle mitochondrial efficiency after weight loss as a novel mechanism for lower energy expenditure

by Higher Education PressTLCL deficiency reduces OXPHOS efficiency. Credit: Patrick J Ferrara, Marisa J Lang, Jordan M Johnson, Shinya Watanabe, Kelsey L McLaughlin, J Alan Maschek, Anthony R P Verker

Updated on: February 05,2024

Increasing skeletal muscle mitochondrial efficiency after weight loss as a novel mechanism for lower energy expenditure

by Higher Education PressTLCL deficiency reduces OXPHOS efficiency. Credit: Patrick J Ferrara, Marisa J Lang, Jordan M Johnson, Shinya Watanabe, Kelsey L McLaughlin, J Alan Maschek, Anthony R P Verker

Updated on:February 05,2024

Chronic lactate exposure leads to cellular disruptions implicated in cancer and possibly T2 diabetes

by CU Anschutz Medical CampusCredit: CC0 Public DomainAcute amounts of lactate like those generated during exercise are probably required for healthy cells, but chronic exposure causes cellular d

Updated on: February 05,2024

Chronic lactate exposure leads to cellular disruptions implicated in cancer and possibly T2 diabetes

by CU Anschutz Medical CampusCredit: CC0 Public DomainAcute amounts of lactate like those generated during exercise are probably required for healthy cells, but chronic exposure causes cellular d

Updated on:February 05,2024