Research links single gene to female infertility

byHudson Institute of Medical ResearchLoss of Fgfr2c from the ovary leads to an absence in primordial germ cells (PGCs), the precursors of the eggs. Immunofluorescence analysis for the germ cell

Updated on: January 17,2024

Research links single gene to female infertility

byHudson Institute of Medical ResearchLoss of Fgfr2c from the ovary leads to an absence in primordial germ cells (PGCs), the precursors of the eggs. Immunofluorescence analysis for the germ cell

Updated on:January 17,2024

Inhibiting production of a key material biosynthesis to slow tumor growth

by Will Doss,Northwestern UniversitySAM inhibitor drastically reduced cancer growth in models of human cancer. Credit: Northwestern UniversityMany cancers hijack a metabolic mechanism known as t

Updated on: February 21,2024

Inhibiting production of a key material biosynthesis to slow tumor growth

by Will Doss,Northwestern UniversitySAM inhibitor drastically reduced cancer growth in models of human cancer. Credit: Northwestern UniversityMany cancers hijack a metabolic mechanism known as t

Updated on:February 21,2024

Reducing stress on T cells makes them better cancer fighters

bySalk InstituteExhausted killer T cells with higher expression of the noradrenaline receptor ADRB1 (cyan) surround sympathetic nerves (yellow) in a virally infected spleen. Killer T cells witho

Updated on: January 20,2024

Reducing stress on T cells makes them better cancer fighters

bySalk InstituteExhausted killer T cells with higher expression of the noradrenaline receptor ADRB1 (cyan) surround sympathetic nerves (yellow) in a virally infected spleen. Killer T cells witho

Updated on:January 20,2024

Dominant form of heart failure caused by metabolic-immune interaction, review article suggests

by UT Southwestern Medical CenterCredit: Pixabay/CC0 Public DomainThe dominant form of heart failure worldwide appears to be caused by a strong, bidirectional interaction between the body's r

Updated on: February 19,2024

Dominant form of heart failure caused by metabolic-immune interaction, review article suggests

by UT Southwestern Medical CenterCredit: Pixabay/CC0 Public DomainThe dominant form of heart failure worldwide appears to be caused by a strong, bidirectional interaction between the body's r

Updated on:February 19,2024

Mom's dietary fat rewires male and female brains differently

by Duke UniversityA microglia (in magenta) from a male mouse born to a mom on a high-fat diet, which sequesters more brain serotonin (in green) than males with mom’s eating a typical lab diet. Th

Updated on: February 21,2024

Mom's dietary fat rewires male and female brains differently

by Duke UniversityA microglia (in magenta) from a male mouse born to a mom on a high-fat diet, which sequesters more brain serotonin (in green) than males with mom’s eating a typical lab diet. Th

Updated on:February 21,2024

Chronic lactate exposure leads to cellular disruptions implicated in cancer and possibly T2 diabetes

by CU Anschutz Medical CampusCredit: CC0 Public DomainAcute amounts of lactate like those generated during exercise are probably required for healthy cells, but chronic exposure causes cellular d

Updated on: February 05,2024

Chronic lactate exposure leads to cellular disruptions implicated in cancer and possibly T2 diabetes

by CU Anschutz Medical CampusCredit: CC0 Public DomainAcute amounts of lactate like those generated during exercise are probably required for healthy cells, but chronic exposure causes cellular d

Updated on:February 05,2024

Scientists discover roles of hypothalamic amino acid sensing in antidepressant effects

by Higher Education PressDeprivation of an essential amino acid leucine exhibits antidepressant effects under chronic stress by stimulating GCN2 and neural activity in AgRP neurons. Credit: Feixiang Y

Updated on: February 03,2024

Scientists discover roles of hypothalamic amino acid sensing in antidepressant effects

by Higher Education PressDeprivation of an essential amino acid leucine exhibits antidepressant effects under chronic stress by stimulating GCN2 and neural activity in AgRP neurons. Credit: Feixiang Y

Updated on:February 03,2024

The neonatal ketone body is important for primordial follicle pool formation and regulates ovarian aging in mice

by Higher Education PressThe working model for the function of ketone bodies in formation of primordial follicle pool. Credit: Xin-Ying Wang et alPremature ovarian aging (POA) refers to an early decli

Updated on: February 21,2024

The neonatal ketone body is important for primordial follicle pool formation and regulates ovarian aging in mice

by Higher Education PressThe working model for the function of ketone bodies in formation of primordial follicle pool. Credit: Xin-Ying Wang et alPremature ovarian aging (POA) refers to an early decli

Updated on:February 21,2024

Researchers develop C. elegans as a model for investigating metabolism variations between individuals

by Jim Fessenden,University of Massachusetts Medical SchoolCaenorhabditis elegans. Credit:KbradnamatEnglish Wikipedia/Wikimedia Commons,CC BY-SA 2.5Using four unrelated s

Updated on: February 19,2024

Researchers develop C. elegans as a model for investigating metabolism variations between individuals

by Jim Fessenden,University of Massachusetts Medical SchoolCaenorhabditis elegans. Credit:KbradnamatEnglish Wikipedia/Wikimedia Commons,CC BY-SA 2.5Using four unrelated s

Updated on:February 19,2024

Small, specific subpopulations of hypothalamic neurons play a major role in regulating the thyroid system

byBoston University School of MedicineCredit: Pixabay/CC0 Public DomainRegulation of thyroid hormone (TH) levels is a complex multilevel phenomenon. The paraventricular nucleus (PVN) of the hypo

Updated on: January 22,2024

Small, specific subpopulations of hypothalamic neurons play a major role in regulating the thyroid system

byBoston University School of MedicineCredit: Pixabay/CC0 Public DomainRegulation of thyroid hormone (TH) levels is a complex multilevel phenomenon. The paraventricular nucleus (PVN) of the hypo

Updated on:January 22,2024

Lifestyle may counter genetic risk for thyroid cancer

by Lori Solomon HealthDay ReporterGenetic and lifestyle factors are independently associated with incident thyroid cancer, according to a study published online Dec. 12 inJAMA Network Open.Xiumi

Updated on: February 21,2024

Lifestyle may counter genetic risk for thyroid cancer

by Lori Solomon HealthDay ReporterGenetic and lifestyle factors are independently associated with incident thyroid cancer, according to a study published online Dec. 12 inJAMA Network Open.Xiumi

Updated on:February 21,2024

Removing a protein could prevent aging and obesity from evolving into metabolic diseases, research suggests

byUniversity of CopenhagenThe ribotoxic stress response drives metabolic maladaptation in obesity and aging. ROS are a physiologically relevant source of translational impairment and activation

Updated on: January 18,2024

Removing a protein could prevent aging and obesity from evolving into metabolic diseases, research suggests

byUniversity of CopenhagenThe ribotoxic stress response drives metabolic maladaptation in obesity and aging. ROS are a physiologically relevant source of translational impairment and activation

Updated on:January 18,2024