Discovery could help reduce adverse side effects of popular next-generation obesity medications

byMonell Chemical Senses CenterActivating GLP1 receptor-expressing neurons in the nucleus tractus solitarius (magenta) increase sateity without causing nausea or aversion. Credit: Alisha Acosta,

Updated on: July 11,2024

Discovery could help reduce adverse side effects of popular next-generation obesity medications

byMonell Chemical Senses CenterActivating GLP1 receptor-expressing neurons in the nucleus tractus solitarius (magenta) increase sateity without causing nausea or aversion. Credit: Alisha Acosta,

Updated on:July 11,2024

Sparse system identification of leptin dynamics in women with obesity

by NYU Tandon School of EngineeringResearchers studyingthe relationship between leptin and obesity found statistically significant relationships between leptin secretion characteristics and

Updated on: January 31,2024

Sparse system identification of leptin dynamics in women with obesity

by NYU Tandon School of EngineeringResearchers studyingthe relationship between leptin and obesity found statistically significant relationships between leptin secretion characteristics and

Updated on:January 31,2024

Suppressed ovarian follicle development in women with obesity may explain reduced fertility

by The Endocrine SocietyCredit: CC0 Public DomainWomen with obesity, even those with regular menstrual cycles, have suppressed ovarian follicle development and reduced production of reproductive

Updated on: January 31,2024

Suppressed ovarian follicle development in women with obesity may explain reduced fertility

by The Endocrine SocietyCredit: CC0 Public DomainWomen with obesity, even those with regular menstrual cycles, have suppressed ovarian follicle development and reduced production of reproductive

Updated on:January 31,2024

Chronic lactate exposure leads to cellular disruptions implicated in cancer and possibly T2 diabetes

by CU Anschutz Medical CampusCredit: CC0 Public DomainAcute amounts of lactate like those generated during exercise are probably required for healthy cells, but chronic exposure causes cellular d

Updated on: February 05,2024

Chronic lactate exposure leads to cellular disruptions implicated in cancer and possibly T2 diabetes

by CU Anschutz Medical CampusCredit: CC0 Public DomainAcute amounts of lactate like those generated during exercise are probably required for healthy cells, but chronic exposure causes cellular d

Updated on:February 05,2024

Inhibiting production of a key material biosynthesis to slow tumor growth

by Will Doss,Northwestern UniversitySAM inhibitor drastically reduced cancer growth in models of human cancer. Credit: Northwestern UniversityMany cancers hijack a metabolic mechanism known as t

Updated on: February 21,2024

Inhibiting production of a key material biosynthesis to slow tumor growth

by Will Doss,Northwestern UniversitySAM inhibitor drastically reduced cancer growth in models of human cancer. Credit: Northwestern UniversityMany cancers hijack a metabolic mechanism known as t

Updated on:February 21,2024

Dominant form of heart failure caused by metabolic-immune interaction, review article suggests

by UT Southwestern Medical CenterCredit: Pixabay/CC0 Public DomainThe dominant form of heart failure worldwide appears to be caused by a strong, bidirectional interaction between the body's r

Updated on: February 19,2024

Dominant form of heart failure caused by metabolic-immune interaction, review article suggests

by UT Southwestern Medical CenterCredit: Pixabay/CC0 Public DomainThe dominant form of heart failure worldwide appears to be caused by a strong, bidirectional interaction between the body's r

Updated on:February 19,2024

Small, specific subpopulations of hypothalamic neurons play a major role in regulating the thyroid system

byBoston University School of MedicineCredit: Pixabay/CC0 Public DomainRegulation of thyroid hormone (TH) levels is a complex multilevel phenomenon. The paraventricular nucleus (PVN) of the hypo

Updated on: January 22,2024

Small, specific subpopulations of hypothalamic neurons play a major role in regulating the thyroid system

byBoston University School of MedicineCredit: Pixabay/CC0 Public DomainRegulation of thyroid hormone (TH) levels is a complex multilevel phenomenon. The paraventricular nucleus (PVN) of the hypo

Updated on:January 22,2024

GDF15 hormone found to make insulin work better

byUniversity of CopenhagenGraphical abstract. Credit:Cell Metabolism(2023). DOI: 10.1016/j.cmet.2023.06.016More than 500 million people worldwide suffer from diabetes. Roughly 2.6 bi

Updated on: January 17,2024

GDF15 hormone found to make insulin work better

byUniversity of CopenhagenGraphical abstract. Credit:Cell Metabolism(2023). DOI: 10.1016/j.cmet.2023.06.016More than 500 million people worldwide suffer from diabetes. Roughly 2.6 bi

Updated on:January 17,2024

The neonatal ketone body is important for primordial follicle pool formation and regulates ovarian aging in mice

by Higher Education PressThe working model for the function of ketone bodies in formation of primordial follicle pool. Credit: Xin-Ying Wang et alPremature ovarian aging (POA) refers to an early decli

Updated on: February 21,2024

The neonatal ketone body is important for primordial follicle pool formation and regulates ovarian aging in mice

by Higher Education PressThe working model for the function of ketone bodies in formation of primordial follicle pool. Credit: Xin-Ying Wang et alPremature ovarian aging (POA) refers to an early decli

Updated on:February 21,2024

Reducing stress on T cells makes them better cancer fighters

bySalk InstituteExhausted killer T cells with higher expression of the noradrenaline receptor ADRB1 (cyan) surround sympathetic nerves (yellow) in a virally infected spleen. Killer T cells witho

Updated on: January 20,2024

Reducing stress on T cells makes them better cancer fighters

bySalk InstituteExhausted killer T cells with higher expression of the noradrenaline receptor ADRB1 (cyan) surround sympathetic nerves (yellow) in a virally infected spleen. Killer T cells witho

Updated on:January 20,2024

A coming wave of diabetes? The link with COVID-19

by Alice McCarthy,Children's Hospital BostonCredit: Unsplash/CC0 Public DomainResearchers are observing a new long-term health concern in patients hospitalized with COVID-19—an increase in n

Updated on: February 03,2024

A coming wave of diabetes? The link with COVID-19

by Alice McCarthy,Children's Hospital BostonCredit: Unsplash/CC0 Public DomainResearchers are observing a new long-term health concern in patients hospitalized with COVID-19—an increase in n

Updated on:February 03,2024

Mouse study: A neural circuit for the suppression of feeding under persistent pain

by Bob Yirka , Medical XpressCredit: Pixabay/CC0 Public DomainA team of researchers from the University of Science and Technology of China and The Second Affiliated Hospital of Anhui Medical Universit

Updated on: February 21,2024

Mouse study: A neural circuit for the suppression of feeding under persistent pain

by Bob Yirka , Medical XpressCredit: Pixabay/CC0 Public DomainA team of researchers from the University of Science and Technology of China and The Second Affiliated Hospital of Anhui Medical Universit

Updated on:February 21,2024