Chronic lactate exposure leads to cellular disruptions implicated in cancer and possibly T2 diabetes

by CU Anschutz Medical CampusCredit: CC0 Public DomainAcute amounts of lactate like those generated during exercise are probably required for healthy cells, but chronic exposure causes cellular d

Updated on: February 05,2024

Chronic lactate exposure leads to cellular disruptions implicated in cancer and possibly T2 diabetes

by CU Anschutz Medical CampusCredit: CC0 Public DomainAcute amounts of lactate like those generated during exercise are probably required for healthy cells, but chronic exposure causes cellular d

Updated on:February 05,2024

Inhibiting production of a key material biosynthesis to slow tumor growth

by Will Doss,Northwestern UniversitySAM inhibitor drastically reduced cancer growth in models of human cancer. Credit: Northwestern UniversityMany cancers hijack a metabolic mechanism known as t

Updated on: February 21,2024

Inhibiting production of a key material biosynthesis to slow tumor growth

by Will Doss,Northwestern UniversitySAM inhibitor drastically reduced cancer growth in models of human cancer. Credit: Northwestern UniversityMany cancers hijack a metabolic mechanism known as t

Updated on:February 21,2024

Scientists redefine obesity with discovery of two major subtypes

by Van Andel Research InstituteDysregulated HDAC-related transcriptome precedes the Nnat+/-p-overgrowth. a, Venn diagram of differential gene expression analyses of islets transcriptome of 6 week

Updated on: February 03,2024

Scientists redefine obesity with discovery of two major subtypes

by Van Andel Research InstituteDysregulated HDAC-related transcriptome precedes the Nnat+/-p-overgrowth. a, Venn diagram of differential gene expression analyses of islets transcriptome of 6 week

Updated on:February 03,2024

Dominant form of heart failure caused by metabolic-immune interaction, review article suggests

by UT Southwestern Medical CenterCredit: Pixabay/CC0 Public DomainThe dominant form of heart failure worldwide appears to be caused by a strong, bidirectional interaction between the body's r

Updated on: February 19,2024

Dominant form of heart failure caused by metabolic-immune interaction, review article suggests

by UT Southwestern Medical CenterCredit: Pixabay/CC0 Public DomainThe dominant form of heart failure worldwide appears to be caused by a strong, bidirectional interaction between the body's r

Updated on:February 19,2024

New guidelines will help pharmacists identify and treat testosterone deficiency as men age

by Gillian Rutherford,University of AlbertaCredit: Unsplash/CC0 Public DomainFatigue, weight gain and low libido are just three of the symptoms middle-aged and older men face as their testostero

Updated on: February 19,2024

New guidelines will help pharmacists identify and treat testosterone deficiency as men age

by Gillian Rutherford,University of AlbertaCredit: Unsplash/CC0 Public DomainFatigue, weight gain and low libido are just three of the symptoms middle-aged and older men face as their testostero

Updated on:February 19,2024

Suppressed ovarian follicle development in women with obesity may explain reduced fertility

by The Endocrine SocietyCredit: CC0 Public DomainWomen with obesity, even those with regular menstrual cycles, have suppressed ovarian follicle development and reduced production of reproductive

Updated on: January 31,2024

Suppressed ovarian follicle development in women with obesity may explain reduced fertility

by The Endocrine SocietyCredit: CC0 Public DomainWomen with obesity, even those with regular menstrual cycles, have suppressed ovarian follicle development and reduced production of reproductive

Updated on:January 31,2024

Does testosterone influence success? Not much, research suggests

by University of BristolBall-and-stick model of the testosterone molecule, C19H28O2, as found in the crystal structure of testosterone monohydrate. Credit: Ben Mills/WikipediaWith the Olympics un

Updated on: February 03,2024

Does testosterone influence success? Not much, research suggests

by University of BristolBall-and-stick model of the testosterone molecule, C19H28O2, as found in the crystal structure of testosterone monohydrate. Credit: Ben Mills/WikipediaWith the Olympics un

Updated on:February 03,2024

New perspectives on metabolic (dysfunction) associated fatty liver disease

by First Hospital of Jilin UniversityCredit: Pixabay/CC0 Public DomainFatty liver disease is a condition characterized by a build-up of fat in the liver and is the most common chronic liver disease th

Updated on: January 17,2024

New perspectives on metabolic (dysfunction) associated fatty liver disease

by First Hospital of Jilin UniversityCredit: Pixabay/CC0 Public DomainFatty liver disease is a condition characterized by a build-up of fat in the liver and is the most common chronic liver disease th

Updated on:January 17,2024

Researchers have uncovered a regulator of body weight that could lead to new treatments for metabolic disorders

by Yale UniversityCredit: Pixabay/CC0 Public DomainYale scientists have discovered that a protein known as augmentor-alpha regulates body weight in mice, an insight that could lead to new treatme

Updated on: February 19,2024

Researchers have uncovered a regulator of body weight that could lead to new treatments for metabolic disorders

by Yale UniversityCredit: Pixabay/CC0 Public DomainYale scientists have discovered that a protein known as augmentor-alpha regulates body weight in mice, an insight that could lead to new treatme

Updated on:February 19,2024

Discovery could help reduce adverse side effects of popular next-generation obesity medications

byMonell Chemical Senses CenterActivating GLP1 receptor-expressing neurons in the nucleus tractus solitarius (magenta) increase sateity without causing nausea or aversion. Credit: Alisha Acosta,

Updated on: July 11,2024

Discovery could help reduce adverse side effects of popular next-generation obesity medications

byMonell Chemical Senses CenterActivating GLP1 receptor-expressing neurons in the nucleus tractus solitarius (magenta) increase sateity without causing nausea or aversion. Credit: Alisha Acosta,

Updated on:July 11,2024

New hope for patients with hereditary metabolic disease

by Fabio Bergamin,ETH ZurichIn methylmalonic aciduria, a specific metabolite accumulates in the body. This often leads to patients requiring intensive medical care. Credit: University Children&#

Updated on: February 19,2024

New hope for patients with hereditary metabolic disease

by Fabio Bergamin,ETH ZurichIn methylmalonic aciduria, a specific metabolite accumulates in the body. This often leads to patients requiring intensive medical care. Credit: University Children&#

Updated on:February 19,2024

Revealing the secrets of cell competition

by Imperial College LondonCredit: CC0 Public DomainCellular competition is a crucial quality control process that ensures that the development of an organism relies on healthy cells. Researchers

Updated on: February 05,2024

Revealing the secrets of cell competition

by Imperial College LondonCredit: CC0 Public DomainCellular competition is a crucial quality control process that ensures that the development of an organism relies on healthy cells. Researchers

Updated on:February 05,2024