Timing calorie intake synchronizes circadian rhythms across multiple systems in mice

by Salk InstituteGraphical abstract. Credit:Cell Metabolism(2023). DOI: 10.1016/j.cmet.2022.12.006Numerous studies have shown health benefits of time-restricted eating including incre

Updated on: January 31,2024

Timing calorie intake synchronizes circadian rhythms across multiple systems in mice

by Salk InstituteGraphical abstract. Credit:Cell Metabolism(2023). DOI: 10.1016/j.cmet.2022.12.006Numerous studies have shown health benefits of time-restricted eating including incre

Updated on:January 31,2024

Implanted cells triggered by electricity used to drive in vivo gene expression

by Justin Jackson , Medical XpressDesign of the direct-current-activated transgene expression switch in mammalian cells.a, Schematic illustration of the stimulation setup for monolayer cultures.

Updated on: January 24,2024

Implanted cells triggered by electricity used to drive in vivo gene expression

by Justin Jackson , Medical XpressDesign of the direct-current-activated transgene expression switch in mammalian cells.a, Schematic illustration of the stimulation setup for monolayer cultures.

Updated on:January 24,2024

New link between diet, intestinal stem cells and disease discovered

by Helmholtz Association of German Research CentresIntestinal stem cells in green, cell division in red. Credit: Helmholtz Munich / Anika BöttcherThe intestine is essential for maintaining our en

Updated on: February 03,2024

New link between diet, intestinal stem cells and disease discovered

by Helmholtz Association of German Research CentresIntestinal stem cells in green, cell division in red. Credit: Helmholtz Munich / Anika BöttcherThe intestine is essential for maintaining our en

Updated on:February 03,2024

Increasing skeletal muscle mitochondrial efficiency after weight loss as a novel mechanism for lower energy expenditure

by Higher Education PressTLCL deficiency reduces OXPHOS efficiency. Credit: Patrick J Ferrara, Marisa J Lang, Jordan M Johnson, Shinya Watanabe, Kelsey L McLaughlin, J Alan Maschek, Anthony R P Verker

Updated on: February 05,2024

Increasing skeletal muscle mitochondrial efficiency after weight loss as a novel mechanism for lower energy expenditure

by Higher Education PressTLCL deficiency reduces OXPHOS efficiency. Credit: Patrick J Ferrara, Marisa J Lang, Jordan M Johnson, Shinya Watanabe, Kelsey L McLaughlin, J Alan Maschek, Anthony R P Verker

Updated on:February 05,2024

Chronic lactate exposure leads to cellular disruptions implicated in cancer and possibly T2 diabetes

by CU Anschutz Medical CampusCredit: CC0 Public DomainAcute amounts of lactate like those generated during exercise are probably required for healthy cells, but chronic exposure causes cellular d

Updated on: February 05,2024

Chronic lactate exposure leads to cellular disruptions implicated in cancer and possibly T2 diabetes

by CU Anschutz Medical CampusCredit: CC0 Public DomainAcute amounts of lactate like those generated during exercise are probably required for healthy cells, but chronic exposure causes cellular d

Updated on:February 05,2024

GKA improves glucose tolerance and induces hepatic lipid accumulation in mice with diet-induced obesity

by KeAi Communications Co.GKA treatment improved glucose tolerance in diet-induced obese mice. (A) Cartoon of the experimental design. (B) The body weight of the chow diet (CD) and high-fat diet (HFD)

Updated on: January 24,2024

GKA improves glucose tolerance and induces hepatic lipid accumulation in mice with diet-induced obesity

by KeAi Communications Co.GKA treatment improved glucose tolerance in diet-induced obese mice. (A) Cartoon of the experimental design. (B) The body weight of the chow diet (CD) and high-fat diet (HFD)

Updated on:January 24,2024

Menopause and the heart connection

by Deb Balzer3D Model of the heart by Dr. Matthew Bramlet. Credit: NIHWomen experience menopause at different ages—and different ways—which can, among other things, affect their heart health.The avera

Updated on: January 31,2024

Menopause and the heart connection

by Deb Balzer3D Model of the heart by Dr. Matthew Bramlet. Credit: NIHWomen experience menopause at different ages—and different ways—which can, among other things, affect their heart health.The avera

Updated on:January 31,2024

People with diabetes may benefit more from a pancreas transplant than other treatments

by The Endocrine SocietyCredit: Pixabay/CC0 Public DomainResults of pancreas transplantation continue to improve and up to 90% of recipients with diabetes enjoy freedom from both insulin therapy

Updated on: February 19,2024

People with diabetes may benefit more from a pancreas transplant than other treatments

by The Endocrine SocietyCredit: Pixabay/CC0 Public DomainResults of pancreas transplantation continue to improve and up to 90% of recipients with diabetes enjoy freedom from both insulin therapy

Updated on:February 19,2024

SMNDC1 loss induces alpha cells to produce insulin

by Austrian Academy of SciencesImmunofluorescence images of alpha cells highlighting induction of insulin protein upon loss of SMNDC1. Credit: Tamara Casteels,CellReport 2022.Beta cells in

Updated on: January 28,2024

SMNDC1 loss induces alpha cells to produce insulin

by Austrian Academy of SciencesImmunofluorescence images of alpha cells highlighting induction of insulin protein upon loss of SMNDC1. Credit: Tamara Casteels,CellReport 2022.Beta cells in

Updated on:January 28,2024

Mouse study: A neural circuit for the suppression of feeding under persistent pain

by Bob Yirka , Medical XpressCredit: Pixabay/CC0 Public DomainA team of researchers from the University of Science and Technology of China and The Second Affiliated Hospital of Anhui Medical Universit

Updated on: February 21,2024

Mouse study: A neural circuit for the suppression of feeding under persistent pain

by Bob Yirka , Medical XpressCredit: Pixabay/CC0 Public DomainA team of researchers from the University of Science and Technology of China and The Second Affiliated Hospital of Anhui Medical Universit

Updated on:February 21,2024

Light physical activity shows promise in reversing childhood obesity caused by being sedentary

by University of Eastern FinlandMean trajectories of movement behaviors from ages 11 through 24 years in 6059 participants and temporal causal longitudinal associations between moderate-to-vigoro

Updated on: March 13,2024

Light physical activity shows promise in reversing childhood obesity caused by being sedentary

by University of Eastern FinlandMean trajectories of movement behaviors from ages 11 through 24 years in 6059 participants and temporal causal longitudinal associations between moderate-to-vigoro

Updated on:March 13,2024

Study offers explanation for why only some develop posttraumatic stress disorder

by Nik Papageorgiou,Ecole Polytechnique Federale de LausanneA map of voxelwise differences in gray matter volume between low-CR and Ctr rats calculated from exvivo magnetic resonance image

Updated on: January 09,2024

Study offers explanation for why only some develop posttraumatic stress disorder

by Nik Papageorgiou,Ecole Polytechnique Federale de LausanneA map of voxelwise differences in gray matter volume between low-CR and Ctr rats calculated from exvivo magnetic resonance image

Updated on:January 09,2024