Scientists discover roles of hypothalamic amino acid sensing in antidepressant effects

by Higher Education PressDeprivation of an essential amino acid leucine exhibits antidepressant effects under chronic stress by stimulating GCN2 and neural activity in AgRP neurons. Credit: Feixiang Y

Updated on: February 03,2024

Scientists discover roles of hypothalamic amino acid sensing in antidepressant effects

by Higher Education PressDeprivation of an essential amino acid leucine exhibits antidepressant effects under chronic stress by stimulating GCN2 and neural activity in AgRP neurons. Credit: Feixiang Y

Updated on:February 03,2024

Light physical activity shows promise in reversing childhood obesity caused by being sedentary

by University of Eastern FinlandMean trajectories of movement behaviors from ages 11 through 24 years in 6059 participants and temporal causal longitudinal associations between moderate-to-vigoro

Updated on: March 13,2024

Light physical activity shows promise in reversing childhood obesity caused by being sedentary

by University of Eastern FinlandMean trajectories of movement behaviors from ages 11 through 24 years in 6059 participants and temporal causal longitudinal associations between moderate-to-vigoro

Updated on:March 13,2024

Unveiling a new mechanism that accelerates aging of adipose tissues

Unveiling a new mechanism that accelerates aging of adipose tissuesbyPohang University of Science and TechnologyMetabolic phenotype affected by aging and adipocyte-specific Crtc2 knockout. Adipo

Updated on: January 24,2024

Unveiling a new mechanism that accelerates aging of adipose tissues

Unveiling a new mechanism that accelerates aging of adipose tissuesbyPohang University of Science and TechnologyMetabolic phenotype affected by aging and adipocyte-specific Crtc2 knockout. Adipo

Updated on:January 24,2024

GDF15 hormone found to make insulin work better

byUniversity of CopenhagenGraphical abstract. Credit:Cell Metabolism(2023). DOI: 10.1016/j.cmet.2023.06.016More than 500 million people worldwide suffer from diabetes. Roughly 2.6 bi

Updated on: January 17,2024

GDF15 hormone found to make insulin work better

byUniversity of CopenhagenGraphical abstract. Credit:Cell Metabolism(2023). DOI: 10.1016/j.cmet.2023.06.016More than 500 million people worldwide suffer from diabetes. Roughly 2.6 bi

Updated on:January 17,2024

Islet transplantation with blood vessel cells shows promise to treat type 1 diabetes

Updated on: April 17,2025

Islet transplantation with blood vessel cells shows promise to treat type 1 diabetes

Updated on:April 17,2025

Excess calories during development may alter the brain and spur adult overeating

by Rutgers UniversityBNST→LHA connectivity is primarily GABAergic and is negatively correlated with early life growth rate. A. Experimental schematic. AAV-Syn-ChR2-eYFP was injected in BNST. B. E

Updated on: February 03,2024

Excess calories during development may alter the brain and spur adult overeating

by Rutgers UniversityBNST→LHA connectivity is primarily GABAergic and is negatively correlated with early life growth rate. A. Experimental schematic. AAV-Syn-ChR2-eYFP was injected in BNST. B. E

Updated on:February 03,2024

Modeling diabetes in minipigs for more accurate testing of potential cell therapies

byKyoto UniversityCredit:Cell Transplantation(2024). DOI: 10.1177/09636897241288932Since the discovery of human iPS cells, a principal goal for researchers worldwide has been to use

Updated on: October 31,2024

Modeling diabetes in minipigs for more accurate testing of potential cell therapies

byKyoto UniversityCredit:Cell Transplantation(2024). DOI: 10.1177/09636897241288932Since the discovery of human iPS cells, a principal goal for researchers worldwide has been to use

Updated on:October 31,2024

Revealing the secrets of cell competition

by Imperial College LondonCredit: CC0 Public DomainCellular competition is a crucial quality control process that ensures that the development of an organism relies on healthy cells. Researchers

Updated on: February 05,2024

Revealing the secrets of cell competition

by Imperial College LondonCredit: CC0 Public DomainCellular competition is a crucial quality control process that ensures that the development of an organism relies on healthy cells. Researchers

Updated on:February 05,2024

GKA improves glucose tolerance and induces hepatic lipid accumulation in mice with diet-induced obesity

by KeAi Communications Co.GKA treatment improved glucose tolerance in diet-induced obese mice. (A) Cartoon of the experimental design. (B) The body weight of the chow diet (CD) and high-fat diet (HFD)

Updated on: January 24,2024

GKA improves glucose tolerance and induces hepatic lipid accumulation in mice with diet-induced obesity

by KeAi Communications Co.GKA treatment improved glucose tolerance in diet-induced obese mice. (A) Cartoon of the experimental design. (B) The body weight of the chow diet (CD) and high-fat diet (HFD)

Updated on:January 24,2024

New link between diet, intestinal stem cells and disease discovered

by Helmholtz Association of German Research CentresIntestinal stem cells in green, cell division in red. Credit: Helmholtz Munich / Anika BöttcherThe intestine is essential for maintaining our en

Updated on: February 03,2024

New link between diet, intestinal stem cells and disease discovered

by Helmholtz Association of German Research CentresIntestinal stem cells in green, cell division in red. Credit: Helmholtz Munich / Anika BöttcherThe intestine is essential for maintaining our en

Updated on:February 03,2024

Exposure to dioxins can worsen thyroid function

byThe Endocrine SocietyCredit: Pixabay/CC0 Public DomainExposure to dioxins can negatively impact thyroid function, according to a study presented Thursday at ENDO 2023, the Endocrine Society&#3

Updated on: January 22,2024

Exposure to dioxins can worsen thyroid function

byThe Endocrine SocietyCredit: Pixabay/CC0 Public DomainExposure to dioxins can negatively impact thyroid function, according to a study presented Thursday at ENDO 2023, the Endocrine Society&#3

Updated on:January 22,2024

The neonatal ketone body is important for primordial follicle pool formation and regulates ovarian aging in mice

by Higher Education PressThe working model for the function of ketone bodies in formation of primordial follicle pool. Credit: Xin-Ying Wang et alPremature ovarian aging (POA) refers to an early decli

Updated on: February 21,2024

The neonatal ketone body is important for primordial follicle pool formation and regulates ovarian aging in mice

by Higher Education PressThe working model for the function of ketone bodies in formation of primordial follicle pool. Credit: Xin-Ying Wang et alPremature ovarian aging (POA) refers to an early decli

Updated on:February 21,2024