Scientists discover roles of hypothalamic amino acid sensing in antidepressant effects

by Higher Education PressDeprivation of an essential amino acid leucine exhibits antidepressant effects under chronic stress by stimulating GCN2 and neural activity in AgRP neurons. Credit: Feixiang Y

Updated on: February 03,2024

Scientists discover roles of hypothalamic amino acid sensing in antidepressant effects

by Higher Education PressDeprivation of an essential amino acid leucine exhibits antidepressant effects under chronic stress by stimulating GCN2 and neural activity in AgRP neurons. Credit: Feixiang Y

Updated on:February 03,2024

Light physical activity shows promise in reversing childhood obesity caused by being sedentary

by University of Eastern FinlandMean trajectories of movement behaviors from ages 11 through 24 years in 6059 participants and temporal causal longitudinal associations between moderate-to-vigoro

Updated on: March 13,2024

Light physical activity shows promise in reversing childhood obesity caused by being sedentary

by University of Eastern FinlandMean trajectories of movement behaviors from ages 11 through 24 years in 6059 participants and temporal causal longitudinal associations between moderate-to-vigoro

Updated on:March 13,2024

Unveiling a new mechanism that accelerates aging of adipose tissues

Unveiling a new mechanism that accelerates aging of adipose tissuesbyPohang University of Science and TechnologyMetabolic phenotype affected by aging and adipocyte-specific Crtc2 knockout. Adipo

Updated on: January 24,2024

Unveiling a new mechanism that accelerates aging of adipose tissues

Unveiling a new mechanism that accelerates aging of adipose tissuesbyPohang University of Science and TechnologyMetabolic phenotype affected by aging and adipocyte-specific Crtc2 knockout. Adipo

Updated on:January 24,2024

The neonatal ketone body is important for primordial follicle pool formation and regulates ovarian aging in mice

by Higher Education PressThe working model for the function of ketone bodies in formation of primordial follicle pool. Credit: Xin-Ying Wang et alPremature ovarian aging (POA) refers to an early decli

Updated on: February 21,2024

The neonatal ketone body is important for primordial follicle pool formation and regulates ovarian aging in mice

by Higher Education PressThe working model for the function of ketone bodies in formation of primordial follicle pool. Credit: Xin-Ying Wang et alPremature ovarian aging (POA) refers to an early decli

Updated on:February 21,2024

Excess calories during development may alter the brain and spur adult overeating

by Rutgers UniversityBNST→LHA connectivity is primarily GABAergic and is negatively correlated with early life growth rate. A. Experimental schematic. AAV-Syn-ChR2-eYFP was injected in BNST. B. E

Updated on: February 03,2024

Excess calories during development may alter the brain and spur adult overeating

by Rutgers UniversityBNST→LHA connectivity is primarily GABAergic and is negatively correlated with early life growth rate. A. Experimental schematic. AAV-Syn-ChR2-eYFP was injected in BNST. B. E

Updated on:February 03,2024

Letting go of extra weight to control sleeping sickness

byInstituto de Medicina MolecularProtective effect of adipocyte lipolysis in murine T. brucei infection. Graphical representation of the effects of ATGL-dependent lipolysis. ATGL activity promot

Updated on: January 17,2024

Letting go of extra weight to control sleeping sickness

byInstituto de Medicina MolecularProtective effect of adipocyte lipolysis in murine T. brucei infection. Graphical representation of the effects of ATGL-dependent lipolysis. ATGL activity promot

Updated on:January 17,2024

We are more satisfied with life as we age, thanks to this neurochemical

by FrontiersSpacefilling model of oxytocin. Created using ACD/ChemSketch 8.0, ACD/3D Viewer and The GIMP. Credit: Wikipedia.People whose brains release more of the neurochemical oxytocin are kind

Updated on: February 19,2024

We are more satisfied with life as we age, thanks to this neurochemical

by FrontiersSpacefilling model of oxytocin. Created using ACD/ChemSketch 8.0, ACD/3D Viewer and The GIMP. Credit: Wikipedia.People whose brains release more of the neurochemical oxytocin are kind

Updated on:February 19,2024

Longer siestas linked to higher risk of obesity, metabolic syndrome and high blood pressure

byBrigham and Women's Hospital(A) Mediated total effect of long siestas vs. no siesta on BMI. (B) Mediated total effect of long siestas vs. no siesta on glucose. (C) Mediated total effect of

Updated on: February 21,2024

Longer siestas linked to higher risk of obesity, metabolic syndrome and high blood pressure

byBrigham and Women's Hospital(A) Mediated total effect of long siestas vs. no siesta on BMI. (B) Mediated total effect of long siestas vs. no siesta on glucose. (C) Mediated total effect of

Updated on:February 21,2024

Understanding the differences between healthy and type 2 diabetes-affected pancreatic islets

by Ananya Sen,University of Illinois at Urbana-ChampaignMass spectroscopic data acquired from multiple samples of the islets of Langerhans have been overlaid on isolated individual human islet o

Updated on: February 03,2024

Understanding the differences between healthy and type 2 diabetes-affected pancreatic islets

by Ananya Sen,University of Illinois at Urbana-ChampaignMass spectroscopic data acquired from multiple samples of the islets of Langerhans have been overlaid on isolated individual human islet o

Updated on:February 03,2024

Removing a protein could prevent aging and obesity from evolving into metabolic diseases, research suggests

byUniversity of CopenhagenThe ribotoxic stress response drives metabolic maladaptation in obesity and aging. ROS are a physiologically relevant source of translational impairment and activation

Updated on: January 18,2024

Removing a protein could prevent aging and obesity from evolving into metabolic diseases, research suggests

byUniversity of CopenhagenThe ribotoxic stress response drives metabolic maladaptation in obesity and aging. ROS are a physiologically relevant source of translational impairment and activation

Updated on:January 18,2024

Osteoporosis drug prescribing often does not follow guidelines

by The Endocrine SocietyCredit: CC0 Public DomainLess than one in 10 commercially insured patients in the United States who broke a hip, a major complication of osteoporosis, receive any osteopor

Updated on: January 31,2024

Osteoporosis drug prescribing often does not follow guidelines

by The Endocrine SocietyCredit: CC0 Public DomainLess than one in 10 commercially insured patients in the United States who broke a hip, a major complication of osteoporosis, receive any osteopor

Updated on:January 31,2024

Exposure to dioxins can worsen thyroid function

byThe Endocrine SocietyCredit: Pixabay/CC0 Public DomainExposure to dioxins can negatively impact thyroid function, according to a study presented Thursday at ENDO 2023, the Endocrine Society&#3

Updated on: January 22,2024

Exposure to dioxins can worsen thyroid function

byThe Endocrine SocietyCredit: Pixabay/CC0 Public DomainExposure to dioxins can negatively impact thyroid function, according to a study presented Thursday at ENDO 2023, the Endocrine Society&#3

Updated on:January 22,2024