Reprogramming of energy metabolism restores cardiac function after infarction in mice

byMax Planck SocietyIn mice with an inactive Cpt1b gene, the heart can regenerate after an infarction. Credit: MPI for Heart and Lung Research, created with Biorender.comAfter birth, the human h

Updated on: January 17,2024

Reprogramming of energy metabolism restores cardiac function after infarction in mice

byMax Planck SocietyIn mice with an inactive Cpt1b gene, the heart can regenerate after an infarction. Credit: MPI for Heart and Lung Research, created with Biorender.comAfter birth, the human h

Updated on:January 17,2024

All that sitting at work is shortening your life

by Ernie MundellYour office chair could be a killer.New research shows that folks who spent most of their workday sitting were 16% more prone to anearly death, compared to folks in non-sitting j

Updated on: March 13,2024

All that sitting at work is shortening your life

by Ernie MundellYour office chair could be a killer.New research shows that folks who spent most of their workday sitting were 16% more prone to anearly death, compared to folks in non-sitting j

Updated on:March 13,2024

Nucleic acid drug iSN40 shows promise for osteoporosis treatment

byShinshu UniversityIn a new study, researchers from Japan reveal that iSN40 suppresses osteoclast differentiation and bone matrix resorption, offering a potential therapeutic approach for osteo

Updated on: January 18,2025

Nucleic acid drug iSN40 shows promise for osteoporosis treatment

byShinshu UniversityIn a new study, researchers from Japan reveal that iSN40 suppresses osteoclast differentiation and bone matrix resorption, offering a potential therapeutic approach for osteo

Updated on:January 18,2025

Belly fat hinders digestive disease medications

by Cedars-Sinai Medical CenterCredit: Pixabay/CC0 Public DomainThe mass and composition of our bodies can significantly affect the way medications are metabolized and absorbed. Investigators at C

Updated on: June 20,2024

Belly fat hinders digestive disease medications

by Cedars-Sinai Medical CenterCredit: Pixabay/CC0 Public DomainThe mass and composition of our bodies can significantly affect the way medications are metabolized and absorbed. Investigators at C

Updated on:June 20,2024

SMNDC1 loss induces alpha cells to produce insulin

by Austrian Academy of SciencesImmunofluorescence images of alpha cells highlighting induction of insulin protein upon loss of SMNDC1. Credit: Tamara Casteels,CellReport 2022.Beta cells in

Updated on: January 28,2024

SMNDC1 loss induces alpha cells to produce insulin

by Austrian Academy of SciencesImmunofluorescence images of alpha cells highlighting induction of insulin protein upon loss of SMNDC1. Credit: Tamara Casteels,CellReport 2022.Beta cells in

Updated on:January 28,2024

Is diabetes remission really as hard to achieve as a new study suggests?

by Duane Mellor, Craig Russell and Srikanth Bellary,The ConversationCredit: Pixabay/CC0 Public DomainIn 2017, alandmark studywas published inThe Lancetshowing that type 2

Updated on: March 05,2024

Is diabetes remission really as hard to achieve as a new study suggests?

by Duane Mellor, Craig Russell and Srikanth Bellary,The ConversationCredit: Pixabay/CC0 Public DomainIn 2017, alandmark studywas published inThe Lancetshowing that type 2

Updated on:March 05,2024

Scientists discover arginine drives metabolic reprogramming to promote tumor growth in liver cancer

byUniversity of BaselTumor organoids (green/blue) are used as a model to study the metabolic changes in liver cell cancer. Credit: Dr. Sandro Nuciforo, Department of Biomedicine, University of B

Updated on: January 18,2024

Scientists discover arginine drives metabolic reprogramming to promote tumor growth in liver cancer

byUniversity of BaselTumor organoids (green/blue) are used as a model to study the metabolic changes in liver cell cancer. Credit: Dr. Sandro Nuciforo, Department of Biomedicine, University of B

Updated on:January 18,2024

Expression of p-STAT3 and c-Myc correlates with P2-HNF4α expression in nonalcoholic fatty liver disease (NAFLD)

by Impact Journals LLCExamples of positive nuclear expression of (A) P1-HNF4α; (B) P2-HNF4α; (C) p-STAT3 and (D) c-Myc and human liver biopsies with non-alcoholic fatty liver disease (NAFLD). 20X micr

Updated on: February 03,2024

Expression of p-STAT3 and c-Myc correlates with P2-HNF4α expression in nonalcoholic fatty liver disease (NAFLD)

by Impact Journals LLCExamples of positive nuclear expression of (A) P1-HNF4α; (B) P2-HNF4α; (C) p-STAT3 and (D) c-Myc and human liver biopsies with non-alcoholic fatty liver disease (NAFLD). 20X micr

Updated on:February 03,2024

Menopause and the heart connection

by Deb Balzer3D Model of the heart by Dr. Matthew Bramlet. Credit: NIHWomen experience menopause at different ages—and different ways—which can, among other things, affect their heart health.The avera

Updated on: January 31,2024

Menopause and the heart connection

by Deb Balzer3D Model of the heart by Dr. Matthew Bramlet. Credit: NIHWomen experience menopause at different ages—and different ways—which can, among other things, affect their heart health.The avera

Updated on:January 31,2024

Low-glucose sensor in the brain promotes blood glucose balance

Updated on: January 22,2024

Low-glucose sensor in the brain promotes blood glucose balance

Updated on:January 22,2024

Babies exposed to cannabis in the womb may be at risk for obesity, high blood sugar

byThe Endocrine SocietyCredit: Pixabay/CC0 Public DomainCannabis use among pregnant women is on the rise and may be associated with negative health outcomes in children, according to a new study

Updated on: February 19,2024

Babies exposed to cannabis in the womb may be at risk for obesity, high blood sugar

byThe Endocrine SocietyCredit: Pixabay/CC0 Public DomainCannabis use among pregnant women is on the rise and may be associated with negative health outcomes in children, according to a new study

Updated on:February 19,2024

Hepatic hydrogen sulfide levels are reduced in mouse model of progeria

by Impact Journals LLCHepatic protein levels of H2S producing enzymes. Credit: 2023 Wilkie et al.Hutchinson-Gilford progeria syndrome (HGPS) is a rare human disease characterized by accelerated biolog

Updated on: January 22,2024

Hepatic hydrogen sulfide levels are reduced in mouse model of progeria

by Impact Journals LLCHepatic protein levels of H2S producing enzymes. Credit: 2023 Wilkie et al.Hutchinson-Gilford progeria syndrome (HGPS) is a rare human disease characterized by accelerated biolog

Updated on:January 22,2024