Study links intestinal glycan modifications to obesity and inflammation

byChiba UniversityChst4–/–mice lacking GlcNAc-6-O-sulfation of the mucinO-glycans showed significant weight gain, increased intestinal inflammation, and significantly reduced immunoglobuli

Updated on: January 18,2024

Study links intestinal glycan modifications to obesity and inflammation

byChiba UniversityChst4–/–mice lacking GlcNAc-6-O-sulfation of the mucinO-glycans showed significant weight gain, increased intestinal inflammation, and significantly reduced immunoglobuli

Updated on:January 18,2024

Researchers identify molecular mechanism by which key protein regulates LDL cholesterol

by University of MontrealCredit: CC0 Public DomainIn a crucial step towards understanding the mechanisms involved in cardiovascular disease and certain cancers, a Canadian led research team has s

Updated on: February 19,2024

Researchers identify molecular mechanism by which key protein regulates LDL cholesterol

by University of MontrealCredit: CC0 Public DomainIn a crucial step towards understanding the mechanisms involved in cardiovascular disease and certain cancers, a Canadian led research team has s

Updated on:February 19,2024

Mitochondria's role in diabetes: Could reversing damage offer a cure?

Updated on: March 17,2025

Mitochondria's role in diabetes: Could reversing damage offer a cure?

Updated on:March 17,2025

Parkinson's, cancer, type 2 diabetes share a key element that drives disease

by Salk InstituteParkin protein (green signal) is in a different part of the cell than the mitochondria (red signal) at time 0 (left image) but then co-localizes with the mitochondria after 60 mi

Updated on: February 19,2024

Parkinson's, cancer, type 2 diabetes share a key element that drives disease

by Salk InstituteParkin protein (green signal) is in a different part of the cell than the mitochondria (red signal) at time 0 (left image) but then co-localizes with the mitochondria after 60 mi

Updated on:February 19,2024

New research sheds light on transcription stimulated by estrogen receptor-α

by Molly Chiu,Baylor College of MedicineGraphical abstract. Credit: DOI: 10.1016/j.isci.2021.103227Gene expression is a highly regulated sequence with many players, one being the estrogen recept

Updated on: February 21,2024

New research sheds light on transcription stimulated by estrogen receptor-α

by Molly Chiu,Baylor College of MedicineGraphical abstract. Credit: DOI: 10.1016/j.isci.2021.103227Gene expression is a highly regulated sequence with many players, one being the estrogen recept

Updated on:February 21,2024

Obesity may lead to a decline in lung function in premenopausal and postmenopausal women

by The North American Menopause SocietyCredit: Unsplash/CC0 Public DomainObesity has been linked to a wide array of health problems. A new study suggests that abdominal obesity as measured by bod

Updated on: January 31,2024

Obesity may lead to a decline in lung function in premenopausal and postmenopausal women

by The North American Menopause SocietyCredit: Unsplash/CC0 Public DomainObesity has been linked to a wide array of health problems. A new study suggests that abdominal obesity as measured by bod

Updated on:January 31,2024

Dietary pyruvate targets cytosolic phospholipase A2 to mitigate inflammation and obesity in mice

by Higher Education PressThe mechanism of action of pyruvate by targeting cPLA2 and inhibiting cPLA2-mediated downstream signaling. Credit: Sadaf Hasan, Nabil Ghani, Xiangli Zhao, Julia Good, Amanda H

Updated on: July 25,2024

Dietary pyruvate targets cytosolic phospholipase A2 to mitigate inflammation and obesity in mice

by Higher Education PressThe mechanism of action of pyruvate by targeting cPLA2 and inhibiting cPLA2-mediated downstream signaling. Credit: Sadaf Hasan, Nabil Ghani, Xiangli Zhao, Julia Good, Amanda H

Updated on:July 25,2024

Lab research finds gluten causes brain inflammation in mice

byUniversity of OtagoCredit: CC0 Public DomainIn what is believed to be a world first discovery, University of Otago researchers have found that wheat gluten causes brain inflammation in mice.Th

Updated on: January 24,2024

Lab research finds gluten causes brain inflammation in mice

byUniversity of OtagoCredit: CC0 Public DomainIn what is believed to be a world first discovery, University of Otago researchers have found that wheat gluten causes brain inflammation in mice.Th

Updated on:January 24,2024

It's time to rethink our attitude toward obesity, academic argues

byTaylor & FrancisCredit: Pixabay from PexelsPrejudice against fat people is endemic in our society and public health initiatives aimed at reducing obesity have only worsened the problem, ac

Updated on: July 09,2024

It's time to rethink our attitude toward obesity, academic argues

byTaylor & FrancisCredit: Pixabay from PexelsPrejudice against fat people is endemic in our society and public health initiatives aimed at reducing obesity have only worsened the problem, ac

Updated on:July 09,2024

Study finds potential strategy for fighting obesity

by UT Southwestern Medical CenterA microscope image from Dr. Williams' lab depicts the arcuate nucleus of the hypothalamus. Green cells are POMC neurons, red cells that are neurons that expre

Updated on: February 19,2024

Study finds potential strategy for fighting obesity

by UT Southwestern Medical CenterA microscope image from Dr. Williams' lab depicts the arcuate nucleus of the hypothalamus. Green cells are POMC neurons, red cells that are neurons that expre

Updated on:February 19,2024

Exposure to a group of widely used 'forever chemicals' may increase diabetes risk in middle-aged women

by DiabetologiaCredit: Pixabay/CC0 Public DomainA new study published inDiabetologiafinds that exposure to per- and polyfluoroalkyl substances (PFAS)—a large and diverse group of indu

Updated on: February 05,2024

Exposure to a group of widely used 'forever chemicals' may increase diabetes risk in middle-aged women

by DiabetologiaCredit: Pixabay/CC0 Public DomainA new study published inDiabetologiafinds that exposure to per- and polyfluoroalkyl substances (PFAS)—a large and diverse group of indu

Updated on:February 05,2024

Prenatal phthalate exposure can significantly impact infant behavior and cognition, says study

by Tejas Mahadevan,Beckman Institute for Advanced Science and TechnologyCredit:Neurotoxicology and Teratology(2022). DOI: 10.1016/j.ntt.2022.107102Prenatal exposure to phthalates, a

Updated on: February 21,2024

Prenatal phthalate exposure can significantly impact infant behavior and cognition, says study

by Tejas Mahadevan,Beckman Institute for Advanced Science and TechnologyCredit:Neurotoxicology and Teratology(2022). DOI: 10.1016/j.ntt.2022.107102Prenatal exposure to phthalates, a

Updated on:February 21,2024