Infecting gut microbes with CRISPR-loaded virus demonstrates potential for microbiome gene editing

by Lindzi Wessel,University of California, San FranciscoEscherichia coli (E. Coli) bacteria. Credit: University of California, San FranciscoIn a first, researchers at the UC San Francisco have s

Updated on: March 28,2024

Infecting gut microbes with CRISPR-loaded virus demonstrates potential for microbiome gene editing

by Lindzi Wessel,University of California, San FranciscoEscherichia coli (E. Coli) bacteria. Credit: University of California, San FranciscoIn a first, researchers at the UC San Francisco have s

Updated on:March 28,2024

Researchers grow intestinal cells from human-induced pluripotent stem cells

by Tokyo Institute of TechnologyHuman-induced pluripotent stem cells derived enterocyte-like cells exhibit P-gp- and BCRP-mediated efflux and cytochrome P450 (CYP3A4)-mediated metabolism. We conc

Updated on: April 09,2024

Researchers grow intestinal cells from human-induced pluripotent stem cells

by Tokyo Institute of TechnologyHuman-induced pluripotent stem cells derived enterocyte-like cells exhibit P-gp- and BCRP-mediated efflux and cytochrome P450 (CYP3A4)-mediated metabolism. We conc

Updated on:April 09,2024

Deep dive into the gut unlocks new disease treatments

byHudson Institute of Medical ResearchAssociate Professor Samuel Forster from Hudson Institute of Medical Research is developing new ways of understanding interactions within the human gut micro

Updated on: January 24,2024

Deep dive into the gut unlocks new disease treatments

byHudson Institute of Medical ResearchAssociate Professor Samuel Forster from Hudson Institute of Medical Research is developing new ways of understanding interactions within the human gut micro

Updated on:January 24,2024

Anti-inflammatory nanoparticles mimic glycocalyx in IBD patients

by WileySchematic summary of the overall flow of the study. A library of glycopolymers was constructed via RAFT polymerization of random combinations of five different sugar moieties at a total f

Updated on: June 06,2024

Anti-inflammatory nanoparticles mimic glycocalyx in IBD patients

by WileySchematic summary of the overall flow of the study. A library of glycopolymers was constructed via RAFT polymerization of random combinations of five different sugar moieties at a total f

Updated on:June 06,2024

Right-sided colon cancer patients have poorer survival than those with left-sided disease

by American College of SurgeonsKiller T cells surround a cancer cell. Credit: NIHORLANDO (July 23, 2018): Patients with colorectal cancer tumors on the right side may have poorer five-year surviv

Updated on: May 07,2024

Right-sided colon cancer patients have poorer survival than those with left-sided disease

by American College of SurgeonsKiller T cells surround a cancer cell. Credit: NIHORLANDO (July 23, 2018): Patients with colorectal cancer tumors on the right side may have poorer five-year surviv

Updated on:May 07,2024

Prevalence of primary sclerosing cholangitis in inflammatory bowel disease explored

(HealthDay)—The pooled prevalence of primary sclerosing cholangitis (PSC) is 2.16 percent in patients with inflammatory bowel disease (IBD), according to a review published in the December issue of&nb

Updated on: May 19,2024

Prevalence of primary sclerosing cholangitis in inflammatory bowel disease explored

(HealthDay)—The pooled prevalence of primary sclerosing cholangitis (PSC) is 2.16 percent in patients with inflammatory bowel disease (IBD), according to a review published in the December issue of&nb

Updated on:May 19,2024

Novel late-stage colorectal cancer treatment proves effective in preclinical models

by Angel Mendez,University of Minnesota Medical SchoolThe low T cells are due to exosomal, immunosuppressive miRNAs that disrupt T cell function and loss of T cells in the tumor environment. Cre

Updated on: April 29,2024

Novel late-stage colorectal cancer treatment proves effective in preclinical models

by Angel Mendez,University of Minnesota Medical SchoolThe low T cells are due to exosomal, immunosuppressive miRNAs that disrupt T cell function and loss of T cells in the tumor environment. Cre

Updated on:April 29,2024

Crohn's disease may be caused by immune signaling failure

by The Scripps Research InstituteScripps Research immunologist Mark Sundrud, PhD, finds a new direction for Crohn's disease research lies in the interplay between bile acids and T cells in th

Updated on: June 01,2024

Crohn's disease may be caused by immune signaling failure

by The Scripps Research InstituteScripps Research immunologist Mark Sundrud, PhD, finds a new direction for Crohn's disease research lies in the interplay between bile acids and T cells in th

Updated on:June 01,2024

Food allergies can be reversed in mice by targeting the microbiome

by American Chemical SocietyCredit: Pixabay/CC0 Public DomainAlthough many people with dietary allergies experience mild symptoms when exposed to triggering foods, some face potentially fatal con

Updated on: March 26,2024

Food allergies can be reversed in mice by targeting the microbiome

by American Chemical SocietyCredit: Pixabay/CC0 Public DomainAlthough many people with dietary allergies experience mild symptoms when exposed to triggering foods, some face potentially fatal con

Updated on:March 26,2024

Novel hybrid operation to treat gastrointestinal bleeding caused by portal vein obstruction

by KeAi Communications Co.Credit: The AuthorsThe portal vein is responsible for collecting blood from the stomach, intestines, and spleen, and transporting it into the liver. However, in some cases, t

Updated on: April 29,2024

Novel hybrid operation to treat gastrointestinal bleeding caused by portal vein obstruction

by KeAi Communications Co.Credit: The AuthorsThe portal vein is responsible for collecting blood from the stomach, intestines, and spleen, and transporting it into the liver. However, in some cases, t

Updated on:April 29,2024

Creating organoids with immune systems

by Cincinnati Children's Hospital Medical CenterCredit:Nature Biotechnology(2023). DOI: 10.1038/s41587-022-01558-xIn many ways, our intestines serve as the front gate between our

Updated on: July 03,2024

Creating organoids with immune systems

by Cincinnati Children's Hospital Medical CenterCredit:Nature Biotechnology(2023). DOI: 10.1038/s41587-022-01558-xIn many ways, our intestines serve as the front gate between our

Updated on:July 03,2024

Gas-related intestinal symptoms affect nearly all adults and are associated with psychological distress

by United European GastroenterologyCredit: Pixabay/CC0 Public DomainGas-related symptoms are associated with poorer quality of life, and higher stress, anxiety and depression, with breaking wind being

Updated on: March 26,2024

Gas-related intestinal symptoms affect nearly all adults and are associated with psychological distress

by United European GastroenterologyCredit: Pixabay/CC0 Public DomainGas-related symptoms are associated with poorer quality of life, and higher stress, anxiety and depression, with breaking wind being

Updated on:March 26,2024